The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||||||
UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | ||||
VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | |||||
NAME OF ISSUER | TITLE OF CLASS | CUSIP | (x$1000) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
10X GENOMICS INC | CL A COM | 88025U109 | 16,097 | 108,063 | SH | DFND | 1 | 108,063 | 0 | 0 | |
2U INC | COM | 90214J101 | 2,341 | 116,653 | SH | DFND | 1 | 116,653 | 0 | 0 | |
2U INC | NOTE 2.250% 5/0 | 90214JAB7 | 1,222 | 1,150,000 | SH | DFND | 1 | 1,150,000 | 0 | 0 | |
51JOB INC | SPONSORED ADS | 316827104 | 715 | 14,622 | SH | DFND | 1 | 14,622 | 0 | 0 | |
ABBOTT LABS | COM | 002824100 | 26,169 | 185,937 | SH | DFND | 1 | 185,937 | 0 | 0 | |
ABBVIE INC | COM | 00287Y109 | 6,279 | 46,376 | SH | DFND | 1 | 46,376 | 0 | 0 | |
ACADIA HEALTHCARE COMPANY IN | COM | 00404A109 | 75,676 | 1,246,729 | SH | DFND | 1 | 1,246,729 | 0 | 0 | |
ACUITY BRANDS INC | COM | 00508Y102 | 580 | 2,740 | SH | DFND | 1 | 2,740 | 0 | 0 | |
ADDUS HOMECARE CORP | COM | 006739106 | 40,497 | 433,077 | SH | DFND | 1 | 433,077 | 0 | 0 | |
ADICET BIO INC | COM | 007002108 | 26,712 | 1,527,273 | SH | DFND | 1 | 1,527,273 | 0 | 0 | |
ADOBE SYSTEMS INCORPORATED | COM | 00724F101 | 191,500 | 337,706 | SH | DFND | 1 | 337,706 | 0 | 0 | |
ADVANCED ENERGY INDS | COM | 007973100 | 269 | 2,950 | SH | DFND | 1 | 2,950 | 0 | 0 | |
ADVANCED MICRO DEVICES INC | COM | 007903107 | 479,041 | 3,328,986 | SH | DFND | 1 | 3,328,986 | 0 | 0 | |
AEVA TECHNOLOGIES INC | COM | 00835Q103 | 171 | 22,601 | SH | DFND | 1 | 22,601 | 0 | 0 | |
AEYE INC | CL A COM | 008183105 | 79 | 16,327 | SH | DFND | 1 | 16,327 | 0 | 0 | |
AFFILIATED MANAGERS GROUP IN | COM | 008252108 | 23,527 | 143,012 | SH | DFND | 1 | 143,012 | 0 | 0 | |
AFLAC INC | COM | 001055102 | 24,962 | 427,500 | SH | DFND | 1 | 427,500 | 0 | 0 | |
AIR PRODS & CHEMS INC | COM | 009158106 | 1,839 | 6,045 | SH | DFND | 1 | 6,045 | 0 | 0 | |
AIR TRANS SVCS GROUP INC | NOTE 1.125%10/1 | 00922RAB1 | 21,920 | 19,615,000 | SH | DFND | 1 | 19,615,000 | 0 | 0 | |
AIRBNB INC | COM CL A | 009066101 | 163,057 | 979,381 | SH | DFND | 1 | 979,381 | 0 | 0 | |
AKAMAI TECHNOLOGIES INC | NOTE 0.375% 9/0 | 00971TAL5 | 17,616 | 15,000,000 | SH | DFND | 1 | 15,000,000 | 0 | 0 | |
AKOYA BIOSCIENCES INC | COM | 00974H104 | 20,140 | 1,315,470 | SH | DFND | 1 | 1,315,470 | 0 | 0 | |
ALARM COM HLDGS INC | COM | 011642105 | 332 | 3,920 | SH | DFND | 1 | 3,920 | 0 | 0 | |
ALBEMARLE CORP | COM | 012653101 | 2,926 | 12,518 | SH | DFND | 1 | 12,518 | 0 | 0 | |
ALCON AG | ORD SHS | H01301128 | 78,774 | 931,494 | SH | DFND | 1,2 | 931,494 | 0 | 0 | |
ALIBABA GROUP HLDG LTD | SPONSORED ADS | 01609W102 | 1,199 | 10,093 | SH | DFND | 1 | 10,093 | 0 | 0 | |
ALIGN TECHNOLOGY INC | COM | 016255101 | 18,007 | 27,400 | SH | DFND | 1 | 27,400 | 0 | 0 | |
ALLEGHANY CORP MD | COM | 017175100 | 109,017 | 163,300 | SH | DFND | 1 | 163,300 | 0 | 0 | |
ALLEGRO MICROSYSTEMS INC | COM | 01749D105 | 725 | 20,033 | SH | DFND | 1 | 20,033 | 0 | 0 | |
ALNYLAM PHARMACEUTICALS INC | COM | 02043Q107 | 90,832 | 535,631 | SH | DFND | 1 | 535,631 | 0 | 0 | |
ALPHABET INC | CAP STK CL A | 02079K305 | 610,766 | 210,824 | SH | DFND | 1 | 210,824 | 0 | 0 | |
ALPHABET INC | CAP STK CL A | 02079K305 | 456,284 | 157,500 | SH | Call | DFND | 1 | 157,500 | 0 | 0 |
ALPHABET INC | CAP STK CL C | 02079K107 | 659,134 | 227,791 | SH | DFND | 1,2 | 227,791 | 0 | 0 | |
ALTAIR ENGR INC | COM CL A | 021369103 | 644 | 8,326 | SH | DFND | 1 | 8,326 | 0 | 0 | |
AMAZON COM INC | COM | 023135106 | 409,657 | 122,860 | SH | DFND | 1 | 122,860 | 0 | 0 | |
AMBARELLA INC | SHS | G037AX101 | 92,622 | 456,514 | SH | DFND | 1 | 456,514 | 0 | 0 | |
AMEDISYS INC | COM | 023436108 | 16,330 | 100,880 | SH | DFND | 1 | 100,880 | 0 | 0 | |
AMERESCO INC | CL A | 02361E108 | 329 | 4,037 | SH | DFND | 1 | 4,037 | 0 | 0 | |
AMERISOURCEBERGEN CORP | COM | 03073E105 | 15,486 | 116,532 | SH | DFND | 1 | 116,532 | 0 | 0 | |
AMETEK INC | COM | 031100100 | 21,505 | 146,250 | SH | DFND | 1 | 146,250 | 0 | 0 | |
AMGEN INC | COM | 031162100 | 6,460 | 28,717 | SH | DFND | 1 | 28,717 | 0 | 0 | |
ANALOG DEVICES INC | COM | 032654105 | 38,496 | 219,011 | SH | DFND | 1 | 219,011 | 0 | 0 | |
ANGIODYNAMICS INC | COM | 03475V101 | 42,686 | 1,547,726 | SH | DFND | 1 | 1,547,726 | 0 | 0 | |
ANSYS INC | COM | 03662Q105 | 6,006 | 14,972 | SH | DFND | 1 | 14,972 | 0 | 0 | |
ANTHEM INC | COM | 036752103 | 37,435 | 80,760 | SH | DFND | 1 | 80,760 | 0 | 0 | |
AON PLC | SHS CL A | G0403H108 | 101,439 | 337,500 | SH | DFND | 1 | 337,500 | 0 | 0 | |
APPLE INC | COM | 037833100 | 894,400 | 5,036,885 | SH | DFND | 1 | 5,036,885 | 0 | 0 | |
APPLE INC | COM | 037833100 | 852,336 | 4,800,000 | SH | Call | DFND | 1 | 4,800,000 | 0 | 0 |
APPLIED MATLS INC | COM | 038222105 | 203,966 | 1,296,174 | SH | DFND | 1 | 1,296,174 | 0 | 0 | |
APTARGROUP INC | COM | 038336103 | 62,658 | 511,577 | SH | DFND | 1 | 511,577 | 0 | 0 | |
APTIV PLC | SHS | G6095L109 | 99,412 | 602,682 | SH | DFND | 1 | 602,682 | 0 | 0 | |
ARCH CAP GROUP LTD | ORD | G0450A105 | 245,515 | 5,523,395 | SH | DFND | 1 | 5,523,395 | 0 | 0 | |
ARCHER AVIATION INC | COM CL A | 03945R102 | 151 | 25,064 | SH | DFND | 1 | 25,064 | 0 | 0 | |
ARCO PLATFORM LTD | COM CL A | G04553106 | 9,455 | 452,594 | SH | DFND | 1 | 452,594 | 0 | 0 | |
ARCUTIS BIOTHERAPEUTICS INC | COM | 03969K108 | 37,000 | 1,784,005 | SH | DFND | 1 | 1,784,005 | 0 | 0 | |
ARENA PHARMACEUTICALS INC | COM NEW | 040047607 | 4,176 | 44,930 | SH | DFND | 1 | 44,930 | 0 | 0 | |
ARES CAPITAL CORP | COM | 04010L103 | 5,424 | 255,972 | SH | DFND | 1 | 255,972 | 0 | 0 | |
ARISTA NETWORKS INC | COM | 040413106 | 258,603 | 1,798,978 | SH | DFND | 1 | 1,798,978 | 0 | 0 | |
ARRAY TECHNOLOGIES INC | COM SHS | 04271T100 | 166 | 10,573 | SH | DFND | 1 | 10,573 | 0 | 0 | |
ARRIVAL GROUP | SHS | L0423Q108 | 495 | 66,714 | SH | DFND | 1 | 66,714 | 0 | 0 | |
ARROWHEAD PHARMACEUTICALS IN | COM | 04280A100 | 1,139 | 17,182 | SH | DFND | 1 | 17,182 | 0 | 0 | |
ATLASSIAN CORP PLC | CL A | G06242104 | 6,589 | 17,280 | SH | DFND | 1 | 17,280 | 0 | 0 | |
ATRICURE INC | COM | 04963C209 | 36,625 | 526,758 | SH | DFND | 1 | 526,758 | 0 | 0 | |
AUTODESK INC | COM | 052769106 | 783 | 2,785 | SH | DFND | 1 | 2,785 | 0 | 0 | |
AVADEL PHARMACEUTICALS PLC | SPONSORED ADR | 05337M104 | 22,581 | 2,794,673 | SH | DFND | 1 | 2,794,673 | 0 | 0 | |
AVANTOR INC | COM | 05352A100 | 75,747 | 1,797,503 | SH | DFND | 1 | 1,797,503 | 0 | 0 | |
AXON ENTERPRISE INC | COM | 05464C101 | 30,826 | 196,342 | SH | DFND | 1 | 196,342 | 0 | 0 | |
AXONICS INC | COM | 05465P101 | 40,853 | 729,518 | SH | DFND | 1 | 729,518 | 0 | 0 | |
BALLARD PWR SYS INC NEW | COM | 058586108 | 776 | 54,746 | SH | DFND | 1 | 54,746 | 0 | 0 | |
BANDWIDTH INC | NOTE 0.250% 3/0 | 05988JAB9 | 1,063 | 1,000,000 | SH | DFND | 1 | 1,000,000 | 0 | 0 | |
BANK OF NT BUTTERFIELD&SON L | SHS NEW | G0772R208 | 7,815 | 205,061 | SH | DFND | 1 | 205,061 | 0 | 0 | |
BAXTER INTL INC | COM | 071813109 | 21,631 | 251,993 | SH | DFND | 1 | 251,993 | 0 | 0 | |
BELLUS HEALTH INC NEW | COM NEW | 07987C204 | 16,100 | 2,000,000 | SH | DFND | 1 | 2,000,000 | 0 | 0 | |
BERKLEY W R CORP | COM | 084423102 | 97,941 | 1,188,750 | SH | DFND | 1 | 1,188,750 | 0 | 0 | |
BERKSHIRE HATHAWAY INC DEL | CL B NEW | 084670702 | 79,992 | 267,531 | SH | DFND | 1 | 267,531 | 0 | 0 | |
BILIBILI INC | SPONS ADS REP Z | 090040106 | 262 | 5,646 | SH | DFND | 1 | 5,646 | 0 | 0 | |
BIO RAD LABS INC | CL A | 090572207 | 78,501 | 103,896 | SH | DFND | 1 | 103,896 | 0 | 0 | |
BIOGEN INC | COM | 09062X103 | 35,988 | 150,000 | SH | DFND | 1 | 150,000 | 0 | 0 | |
BIOHAVEN PHARMACTL HLDG CO L | COM | G11196105 | 177,028 | 1,284,580 | SH | DFND | 1 | 1,284,580 | 0 | 0 | |
BIOMARIN PHARMACEUTICAL INC | COM | 09061G101 | 11,044 | 125,000 | SH | DFND | 1 | 125,000 | 0 | 0 | |
BK OF AMERICA CORP | COM | 060505104 | 27,290 | 613,389 | SH | DFND | 1 | 613,389 | 0 | 0 | |
BLACKLINE INC | COM | 09239B109 | 14,781 | 142,754 | SH | DFND | 1 | 142,754 | 0 | 0 | |
BLACKSTONE INC | COM | 09260D107 | 10,491 | 81,078 | SH | DFND | 1 | 81,078 | 0 | 0 | |
BLINK CHARGING CO | COM | 09354A100 | 206 | 7,762 | SH | DFND | 1 | 7,762 | 0 | 0 | |
BLOCK INC | CL A | 852234103 | 14,312 | 88,615 | SH | DFND | 1 | 88,615 | 0 | 0 | |
BLOOM ENERGY CORP | COM CL A | 093712107 | 301 | 13,739 | SH | DFND | 1 | 13,739 | 0 | 0 | |
BLUEPRINT MEDICINES CORP | COM | 09627Y109 | 26,778 | 250,000 | SH | DFND | 1 | 250,000 | 0 | 0 | |
BOOKING HOLDINGS INC | COM | 09857L108 | 13,162 | 5,486 | SH | DFND | 1 | 5,486 | 0 | 0 | |
BORGWARNER INC | COM | 099724106 | 1,056 | 23,432 | SH | DFND | 1 | 23,432 | 0 | 0 | |
BOSTON SCIENTIFIC CORP | COM | 101137107 | 90,357 | 2,127,059 | SH | DFND | 1 | 2,127,059 | 0 | 0 | |
BRISTOL-MYERS SQUIBB CO | COM | 110122108 | 64,588 | 1,035,901 | SH | DFND | 1 | 1,035,901 | 0 | 0 | |
BROADCOM INC | COM | 11135F101 | 783 | 1,177 | SH | DFND | 1 | 1,177 | 0 | 0 | |
CANADIAN NAT RES LTD | COM | 136385101 | 30,715 | 644,149 | SH | DFND | 1 | 644,149 | 0 | 0 | |
CANNAE HLDGS INC | COM | 13765N107 | 17,683 | 503,086 | SH | DFND | 1 | 503,086 | 0 | 0 | |
CANOO INC | COM CL A | 13803R102 | 195 | 25,218 | SH | DFND | 1 | 25,218 | 0 | 0 | |
CARRIER GLOBAL CORPORATION | COM | 14448C104 | 783 | 14,435 | SH | DFND | 1 | 14,435 | 0 | 0 | |
CASTLE BIOSCIENCES INC | COM | 14843C105 | 1,929 | 44,985 | SH | DFND | 1 | 44,985 | 0 | 0 | |
CATALENT INC | COM | 148806102 | 6,213 | 48,527 | SH | DFND | 1 | 48,527 | 0 | 0 | |
CELLDEX THERAPEUTICS INC NEW | COM NEW | 15117B202 | 38,640 | 1,000,000 | SH | DFND | 1 | 1,000,000 | 0 | 0 | |
CENTENE CORP DEL | COM | 15135B101 | 32,270 | 391,632 | SH | DFND | 1 | 391,632 | 0 | 0 | |
CERENCE INC | COM | 156727109 | 317 | 4,136 | SH | DFND | 1 | 4,136 | 0 | 0 | |
CEREVEL THERAPEUTICS HLDNG I | COM | 15678U128 | 24,315 | 750,000 | SH | DFND | 1 | 750,000 | 0 | 0 | |
CERUS CORP | COM | 157085101 | 13,546 | 1,989,199 | SH | DFND | 1 | 1,989,199 | 0 | 0 | |
CHANGE HEALTHCARE INC | UNIT 99/99/9999 | 15912K209 | 38,891 | 553,452 | SH | DFND | 1 | 553,452 | 0 | 0 | |
CHARGEPOINT HOLDINGS INC | COM CL A | 15961R105 | 1,187 | 62,322 | SH | DFND | 1 | 62,322 | 0 | 0 | |
CHART INDS INC | COM | 16115Q308 | 1,067 | 6,692 | SH | DFND | 1 | 6,692 | 0 | 0 | |
CHEGG INC | NOTE 0.125% 3/1 | 163092AD1 | 1,733 | 1,750,000 | SH | DFND | 1 | 1,750,000 | 0 | 0 | |
CHEMED CORP NEW | COM | 16359R103 | 7,163 | 13,539 | SH | DFND | 1 | 13,539 | 0 | 0 | |
CHUBB LIMITED | COM | H1467J104 | 199,541 | 1,032,232 | SH | DFND | 1 | 1,032,232 | 0 | 0 | |
CITIGROUP INC | COM NEW | 172967424 | 14,790 | 244,915 | SH | DFND | 1 | 244,915 | 0 | 0 | |
CITIZENS FINL GROUP INC | COM | 174610105 | 19,203 | 406,411 | SH | DFND | 1 | 406,411 | 0 | 0 | |
CITRIX SYS INC | COM | 177376100 | 783 | 8,277 | SH | DFND | 1 | 8,277 | 0 | 0 | |
COGNEX CORP | COM | 192422103 | 7,500 | 96,450 | SH | DFND | 1 | 96,450 | 0 | 0 | |
CONMED CORP | COM | 207410101 | 1,413 | 9,969 | SH | DFND | 1 | 9,969 | 0 | 0 | |
CONSTELLIUM SE | CL A SHS | F21107101 | 265 | 14,784 | SH | DFND | 1 | 14,784 | 0 | 0 | |
COOPER COS INC | COM NEW | 216648402 | 77,715 | 185,504 | SH | DFND | 1 | 185,504 | 0 | 0 | |
COUPA SOFTWARE INC | COM | 22266L106 | 52,028 | 329,185 | SH | DFND | 1 | 329,185 | 0 | 0 | |
CRITEO S A | SPONS ADS | 226718104 | 7,749 | 199,345 | SH | DFND | 1 | 199,345 | 0 | 0 | |
CROWDSTRIKE HLDGS INC | CL A | 22788C105 | 102,742 | 501,791 | SH | DFND | 1 | 501,791 | 0 | 0 | |
CS DISCO INC | COM | 126327105 | 5,480 | 153,289 | SH | DFND | 1 | 153,289 | 0 | 0 | |
CSG SYS INTL INC | NOTE 4.250% 3/1 | 126349AF6 | 28,671 | 27,000,000 | SH | DFND | 1 | 27,000,000 | 0 | 0 | |
CUMMINS INC | COM | 231021106 | 1,056 | 4,841 | SH | DFND | 1 | 4,841 | 0 | 0 | |
CURIS INC | COM NEW | 231269200 | 3,402 | 714,700 | SH | DFND | 1 | 714,700 | 0 | 0 | |
CVS HEALTH CORP | COM | 126650100 | 82,279 | 797,585 | SH | DFND | 1 | 797,585 | 0 | 0 | |
CYBERARK SOFTWARE LTD | NOTE 11/1 | 23248VAB1 | 3,795 | 3,000,000 | SH | DFND | 1 | 3,000,000 | 0 | 0 | |
CYBERARK SOFTWARE LTD | SHS | M2682V108 | 128,898 | 743,870 | SH | DFND | 1 | 743,870 | 0 | 0 | |
CYTOKINETICS INC | COM NEW | 23282W605 | 167,368 | 3,671,969 | SH | DFND | 1 | 3,671,969 | 0 | 0 | |
DANA INC | COM | 235825205 | 348 | 15,233 | SH | DFND | 1 | 15,233 | 0 | 0 | |
DECIPHERA PHARMACEUTICALS IN | COM | 24344T101 | 1,593 | 163,100 | SH | DFND | 1 | 163,100 | 0 | 0 | |
DENALI THERAPEUTICS INC | COM | 24823R105 | 2,401 | 53,835 | SH | DFND | 1 | 53,835 | 0 | 0 | |
DEXCOM INC | COM | 252131107 | 23,935 | 44,576 | SH | DFND | 1 | 44,576 | 0 | 0 | |
DEXCOM INC | NOTE 0.250%11/1 | 252131AK3 | 8,939 | 7,500,000 | SH | DFND | 1 | 7,500,000 | 0 | 0 | |
DIDI GLOBAL INC | SPONSORED ADS | 23292E108 | 1,056 | 212,061 | SH | DFND | 1 | 212,061 | 0 | 0 | |
DIODES INC | COM | 254543101 | 387 | 3,525 | SH | DFND | 1 | 3,525 | 0 | 0 | |
DOCUSIGN INC | COM | 256163106 | 60,328 | 396,089 | SH | DFND | 1 | 396,089 | 0 | 0 | |
DOLBY LABORATORIES INC | COM CL A | 25659T107 | 92,042 | 966,626 | SH | DFND | 1 | 966,626 | 0 | 0 | |
DOLLAR GEN CORP NEW | COM | 256677105 | 4,217 | 17,882 | SH | DFND | 2 | 17,882 | 0 | 0 | |
DUN & BRADSTREET HLDGS INC | COM | 26484T106 | 4,850 | 236,714 | SH | DFND | 2 | 236,714 | 0 | 0 | |
EAST WEST BANCORP INC | COM | 27579R104 | 14,525 | 184,609 | SH | DFND | 1 | 184,609 | 0 | 0 | |
EATON CORP PLC | SHS | G29183103 | 783 | 4,531 | SH | DFND | 1 | 4,531 | 0 | 0 | |
EBAY INC. | COM | 278642103 | 8,686 | 130,614 | SH | DFND | 1 | 130,614 | 0 | 0 | |
EDWARDS LIFESCIENCES CORP | COM | 28176E108 | 12,253 | 94,583 | SH | DFND | 1 | 94,583 | 0 | 0 | |
ELASTIC N V | ORD SHS | N14506104 | 132,683 | 1,077,938 | SH | DFND | 1 | 1,077,938 | 0 | 0 | |
ELECTRAMECCANICA VEHS CORP | COM NEW | 284849205 | 28 | 12,139 | SH | DFND | 1 | 12,139 | 0 | 0 | |
ELECTRIC LAST MILE SOLUTNS I | CLASS A COM | 28489L104 | 97 | 13,759 | SH | DFND | 1 | 13,759 | 0 | 0 | |
EMERSON ELEC CO | COM | 291011104 | 16,199 | 174,234 | SH | DFND | 1 | 174,234 | 0 | 0 | |
ENCOMPASS HEALTH CORP | COM | 29261A100 | 59,331 | 909,154 | SH | DFND | 1 | 909,154 | 0 | 0 | |
ENERSYS | COM | 29275Y102 | 2,892 | 36,580 | SH | DFND | 1 | 36,580 | 0 | 0 | |
ENOVIX CORPORATION | COM | 293594107 | 729 | 26,710 | SH | DFND | 1 | 26,710 | 0 | 0 | |
ENPHASE ENERGY INC | COM | 29355A107 | 783 | 4,280 | SH | DFND | 1 | 4,280 | 0 | 0 | |
ENTERPRISE FINL SVCS CORP | COM | 293712105 | 9,223 | 195,869 | SH | DFND | 1 | 195,869 | 0 | 0 | |
ENVISTA HOLDINGS CORPORATION | COM | 29415F104 | 83,684 | 1,857,166 | SH | DFND | 1 | 1,857,166 | 0 | 0 | |
EPAM SYS INC | COM | 29414B104 | 24,701 | 36,952 | SH | DFND | 1 | 36,952 | 0 | 0 | |
ESQUIRE FINL HLDGS INC | COM | 29667J101 | 749 | 23,774 | SH | DFND | 1 | 23,774 | 0 | 0 | |
ESSENT GROUP LTD | COM | G3198U102 | 98,891 | 2,172,000 | SH | DFND | 1 | 2,172,000 | 0 | 0 | |
ESTABLISHMENT LABS HLDGS INC | COM | G31249108 | 666 | 9,847 | SH | DFND | 1 | 9,847 | 0 | 0 | |
EURONET WORLDWIDE INC | COM | 298736109 | 1,251 | 10,500 | SH | DFND | 2 | 10,500 | 0 | 0 | |
EVERBRIDGE INC | COM | 29978A104 | 74,879 | 1,112,124 | SH | DFND | 1 | 1,112,124 | 0 | 0 | |
EVEREST RE GROUP LTD | COM | G3223R108 | 69,370 | 253,250 | SH | DFND | 1 | 253,250 | 0 | 0 | |
EVGO INC | CL A COM | 30052F100 | 484 | 48,649 | SH | DFND | 1 | 48,649 | 0 | 0 | |
EVOLENT HEALTH INC | CL A | 30050B101 | 1,084 | 39,188 | SH | DFND | 1 | 39,188 | 0 | 0 | |
EXELIXIS INC | COM | 30161Q104 | 80,471 | 4,402,147 | SH | DFND | 1 | 4,402,147 | 0 | 0 | |
FARADAY FUTRE INTLGT ELCTR I | COM | 307359109 | 317 | 59,651 | SH | DFND | 1 | 59,651 | 0 | 0 | |
FERGUSON PLC NEW | SHS | G3421J106 | 5,572,147 | 262,157 | SH | DFND | 1 | 262,157 | 0 | 0 | |
FIDELITY NATL INFORMATION SV | COM | 31620M106 | 19,680 | 180,302 | SH | DFND | 2 | 180,302 | 0 | 0 | |
FIRST AMERN FINL CORP | COM | 31847R102 | 40,640 | 519,500 | SH | DFND | 1 | 519,500 | 0 | 0 | |
FIRST REP BK SAN FRANCISCO C | COM | 33616C100 | 5,883 | 28,490 | SH | DFND | 1 | 28,490 | 0 | 0 | |
FIRST SOLAR INC | COM | 336433107 | 726 | 8,326 | SH | DFND | 1 | 8,326 | 0 | 0 | |
FISERV INC | COM | 337738108 | 19,517 | 188,040 | SH | DFND | 1 | 188,040 | 0 | 0 | |
FISKER INC | CL A COM STK | 33813J106 | 858 | 54,569 | SH | DFND | 1 | 54,569 | 0 | 0 | |
FIVE9 INC | COM | 338307101 | 153,796 | 1,119,985 | SH | DFND | 1 | 1,119,985 | 0 | 0 | |
FREYR BATTERY | SHS | L4135L100 | 239 | 21,412 | SH | DFND | 1 | 21,412 | 0 | 0 | |
FUELCELL ENERGY INC | COM | 35952H601 | 149 | 28,710 | SH | DFND | 1 | 28,710 | 0 | 0 | |
FULCRUM THERAPEUTICS INC | COM | 359616109 | 8,845 | 500,000 | SH | DFND | 1 | 500,000 | 0 | 0 | |
GARMIN LTD | SHS | H2906T109 | 1,150 | 8,446 | SH | DFND | 1 | 8,446 | 0 | 0 | |
GENERAC HLDGS INC | COM | 368736104 | 783 | 2,224 | SH | DFND | 1 | 2,224 | 0 | 0 | |
GENERAL DYNAMICS CORP | COM | 369550108 | 2,208 | 10,591 | SH | DFND | 2 | 10,591 | 0 | 0 | |
GENTEX CORP | COM | 371901109 | 871 | 24,979 | SH | DFND | 1 | 24,979 | 0 | 0 | |
GLOBAL BLOOD THERAPEUTICS IN | COM | 37890U108 | 26,952 | 920,810 | SH | DFND | 1 | 920,810 | 0 | 0 | |
GLOBUS MED INC | CL A | 379577208 | 54,454 | 754,204 | SH | DFND | 1 | 754,204 | 0 | 0 | |
GOLUB CAP BDC INC | COM | 38173M102 | 4,444 | 287,850 | SH | DFND | 1 | 287,850 | 0 | 0 | |
GUARDANT HEALTH INC | COM | 40131M109 | 13,048 | 130,458 | SH | DFND | 1 | 130,458 | 0 | 0 | |
HDFC BANK LTD | SPONSORED ADS | 40415F101 | 637 | 9,786 | SH | DFND | 1 | 9,786 | 0 | 0 | |
HEALTH CATALYST INC | COM | 42225T107 | 277 | 7,000 | SH | DFND | 1 | 7,000 | 0 | 0 | |
HEALTHEQUITY INC | COM | 42226A107 | 476 | 10,770 | SH | DFND | 1 | 10,770 | 0 | 0 | |
HOLOGIC INC | COM | 436440101 | 15,154 | 197,937 | SH | DFND | 1 | 197,937 | 0 | 0 | |
HORIZON THERAPEUTICS PUB L | SHS | G46188101 | 177,183 | 1,644,241 | SH | DFND | 1 | 1,644,241 | 0 | 0 | |
HUBBELL INC | COM | 443510607 | 783 | 3,760 | SH | DFND | 1 | 3,760 | 0 | 0 | |
HUBSPOT INC | COM | 443573100 | 165,270 | 250,732 | SH | DFND | 1 | 250,732 | 0 | 0 | |
HYLIION HOLDINGS CORP | COMMON STOCK | 449109107 | 198 | 31,874 | SH | DFND | 1 | 31,874 | 0 | 0 | |
HYZON MOTORS INC | COM CL A | 44951Y102 | 170 | 26,153 | SH | DFND | 1 | 26,153 | 0 | 0 | |
IAC INTERACTIVECORP NEW | COM NEW | 44891N208 | 19,442 | 148,741 | SH | DFND | 1 | 148,741 | 0 | 0 | |
ICON PLC | SHS | G4705A100 | 32,221 | 104,039 | SH | DFND | 1 | 104,039 | 0 | 0 | |
IDEANOMICS INC | COM | 45166V106 | 63 | 52,558 | SH | DFND | 1 | 52,558 | 0 | 0 | |
IGM BIOSCIENCES INC | COM | 449585108 | 3,122 | 106,436 | SH | DFND | 1 | 106,436 | 0 | 0 | |
II-VI INC | COM | 902104108 | 568 | 8,311 | SH | DFND | 1 | 8,311 | 0 | 0 | |
ILLUMINA INC | COM | 452327109 | 344 | 904 | SH | DFND | 1 | 904 | 0 | 0 | |
IMPINJ INC | COM | 453204109 | 5,191 | 58,527 | SH | DFND | 1 | 58,527 | 0 | 0 | |
INCYTE CORP | COM | 45337C102 | 37,095 | 505,386 | SH | DFND | 1 | 505,386 | 0 | 0 | |
INDIE SEMICONDUCTOR INC | CLASS A COM | 45569U101 | 165 | 13,737 | SH | DFND | 1 | 13,737 | 0 | 0 | |
INFINITY PHARMACEUTICALS INC | COM | 45665G303 | 11,250 | 5,000,000 | SH | DFND | 1 | 5,000,000 | 0 | 0 | |
INNOVIZ TECHNOLOGIES LTD | SHS | M5R635108 | 90 | 14,120 | SH | DFND | 1 | 14,120 | 0 | 0 | |
INSMED INC | COM PAR $.01 | 457669307 | 48,983 | 1,798,209 | SH | DFND | 1 | 1,798,209 | 0 | 0 | |
INSPIRE MED SYS INC | COM | 457730109 | 477 | 2,075 | SH | DFND | 1 | 2,075 | 0 | 0 | |
INTERCONTINENTAL EXCHANGE IN | COM | 45866F104 | 20,997 | 153,523 | SH | DFND | 1 | 153,523 | 0 | 0 | |
INTRA-CELLULAR THERAPIES INC | COM | 46116X101 | 4,801 | 91,735 | SH | DFND | 1 | 91,735 | 0 | 0 | |
INTUITIVE SURGICAL INC | COM NEW | 46120E602 | 12,309 | 34,259 | SH | DFND | 1 | 34,259 | 0 | 0 | |
IPG PHOTONICS CORP | COM | 44980X109 | 719 | 4,174 | SH | DFND | 1 | 4,174 | 0 | 0 | |
IQIYI INC | NOTE 2.000% 4/0 | 46267XAD0 | 73 | 100,000 | SH | DFND | 1 | 100,000 | 0 | 0 | |
ITRON INC | COM | 465741106 | 972 | 14,185 | SH | DFND | 1 | 14,185 | 0 | 0 | |
IVERIC BIO INC | COM | 46583P102 | 31,096 | 1,859,817 | SH | DFND | 1 | 1,859,817 | 0 | 0 | |
JAMES RIV GROUP LTD | COM | G5005R107 | 25,929 | 900,000 | SH | DFND | 1 | 900,000 | 0 | 0 | |
JAZZ PHARMACEUTICALS PLC | SHS USD | G50871105 | 44,590 | 350,000 | SH | DFND | 1 | 350,000 | 0 | 0 | |
JD.COM INC | SPON ADR CL A | 47215P106 | 864 | 12,335 | SH | DFND | 1 | 12,335 | 0 | 0 | |
JOBY AVIATION INC | COMMON STOCK | G65163100 | 466 | 63,776 | SH | DFND | 1 | 63,776 | 0 | 0 | |
JOHNSON & JOHNSON | COM | 478160104 | 50,393 | 294,575 | SH | DFND | 1 | 294,575 | 0 | 0 | |
JOHNSON CTLS INTL PLC | SHS | G51502105 | 3,426 | 42,130 | SH | DFND | 1 | 42,130 | 0 | 0 | |
JPMORGAN CHASE & CO | COM | 46625H100 | 38,791 | 244,968 | SH | DFND | 1 | 244,968 | 0 | 0 | |
KE HLDGS INC | SPONSORED ADS | 482497104 | 319 | 15,861 | SH | DFND | 1 | 15,861 | 0 | 0 | |
KLA CORP | COM NEW | 482480100 | 182,281 | 423,801 | SH | DFND | 1 | 423,801 | 0 | 0 | |
KORNIT DIGITAL LTD | SHS | M6372Q113 | 68,036 | 446,873 | SH | DFND | 1 | 446,873 | 0 | 0 | |
LABORATORY CORP AMER HLDGS | COM NEW | 50540R409 | 9,384 | 29,864 | SH | DFND | 1,2 | 29,864 | 0 | 0 | |
LANTHEUS HLDGS INC | COM | 516544103 | 1,316 | 45,543 | SH | DFND | 1 | 45,543 | 0 | 0 | |
LATTICE SEMICONDUCTOR CORP | COM | 518415104 | 161,661 | 2,097,857 | SH | DFND | 1 | 2,097,857 | 0 | 0 | |
LEAR CORP | COM NEW | 521865204 | 1,056 | 5,773 | SH | DFND | 1 | 5,773 | 0 | 0 | |
LI AUTO INC | SPONSORED ADS | 50202M102 | 1,839 | 57,292 | SH | DFND | 1 | 57,292 | 0 | 0 | |
LIBERTY MEDIA CORP DEL | COM SER C FRMLA | 531229854 | 16,113 | 254,791 | SH | DFND | 1 | 254,791 | 0 | 0 | |
LI-CYCLE HOLDINGS CORP | COMMON SHARES | 50202P105 | 299 | 30,008 | SH | DFND | 1 | 30,008 | 0 | 0 | |
LILIUM N V | CLASS A ORD SHS | N52586109 | 208 | 30,004 | SH | DFND | 1 | 30,004 | 0 | 0 | |
LILLY ELI & CO | COM | 532457108 | 12,993 | 47,040 | SH | DFND | 1 | 47,040 | 0 | 0 | |
LINDE PLC | SHS | G5494J103 | 4,459 | 11,539 | SH | DFND | 1 | 11,539 | 0 | 0 | |
LITHIUM AMERS CORP NEW | COM NEW | 53680Q207 | 726 | 22,108 | SH | DFND | 1 | 22,108 | 0 | 0 | |
LITTELFUSE INC | COM | 537008104 | 34,996 | 111,212 | SH | DFND | 1 | 111,212 | 0 | 0 | |
LIVANOVA PLC | SHS | G5509L101 | 64,582 | 738,666 | SH | DFND | 1 | 738,666 | 0 | 0 | |
LIVE NATION ENTERTAINMENT IN | NOTE 2.500% 3/1 | 538034AQ2 | 1,810 | 1,000,000 | SH | DFND | 1 | 1,000,000 | 0 | 0 | |
LIVENT CORP | COM | 53814L108 | 1,017 | 41,714 | SH | DFND | 1 | 41,714 | 0 | 0 | |
LIVERAMP HLDGS INC | COM | 53815P108 | 10,963 | 228,642 | SH | DFND | 1 | 228,642 | 0 | 0 | |
LOGITECH INTL S A | SHS | H50430232 | 17,482 | 217,101 | SH | DFND | 1 | 217,101 | 0 | 0 | |
LORDSTOWN MOTORS CORP | COM CL A | 54405Q100 | 70 | 20,300 | SH | DFND | 1 | 20,300 | 0 | 0 | |
LPL FINL HLDGS INC | COM | 50212V100 | 20,789 | 129,858 | SH | DFND | 1 | 129,858 | 0 | 0 | |
LUCID GROUP INC | COM | 549498103 | 1,839 | 48,332 | SH | DFND | 1 | 48,332 | 0 | 0 | |
LUMENTUM HLDGS INC | COM | 55024U109 | 2,534 | 23,961 | SH | DFND | 1 | 23,961 | 0 | 0 | |
LUMENTUM HLDGS INC | NOTE 0.500%12/1 | 55024UAD1 | 6,868 | 5,500,000 | SH | DFND | 1 | 5,500,000 | 0 | 0 | |
LUMINAR TECHNOLOGIES INC | COM CL A | 550424105 | 646 | 38,182 | SH | DFND | 1 | 38,182 | 0 | 0 | |
LYFT INC | CL A COM | 55087P104 | 1,056 | 24,714 | SH | DFND | 1 | 24,714 | 0 | 0 | |
MAGNA INTL INC | COM | 559222401 | 1,192 | 13,052 | SH | DFND | 1 | 13,052 | 0 | 0 | |
MARKEL CORP | COM | 570535104 | 123,462 | 100,050 | SH | DFND | 1 | 100,050 | 0 | 0 | |
MARSH & MCLENNAN COS INC | COM | 571748102 | 184,249 | 1,060,000 | SH | DFND | 1 | 1,060,000 | 0 | 0 | |
MARVELL TECHNOLOGY INC | COM | 573874104 | 290,915 | 3,325,125 | SH | DFND | 1 | 3,325,125 | 0 | 0 | |
MASIMO CORP | COM | 574795100 | 3,965 | 13,544 | SH | DFND | 1 | 13,544 | 0 | 0 | |
MASTEC INC | COM | 576323109 | 537 | 5,818 | SH | DFND | 1 | 5,818 | 0 | 0 | |
MASTERCARD INCORPORATED | CL A | 57636Q104 | 85,660 | 238,396 | SH | DFND | 1 | 238,396 | 0 | 0 | |
MATCH GROUP INC NEW | COM | 57667L107 | 58,614 | 443,205 | SH | DFND | 1 | 443,205 | 0 | 0 | |
MEDTRONIC PLC | SHS | G5960L103 | 22,462 | 217,132 | SH | DFND | 1 | 217,132 | 0 | 0 | |
MERCADOLIBRE INC | COM | 58733R102 | 45,762 | 33,938 | SH | DFND | 1 | 33,938 | 0 | 0 | |
MERIDIAN BIOSCIENCE INC | COM | 589584101 | 683 | 33,463 | SH | DFND | 1 | 33,463 | 0 | 0 | |
MERIT MED SYS INC | COM | 589889104 | 38,353 | 615,621 | SH | DFND | 1 | 615,621 | 0 | 0 | |
META PLATFORMS INC | CL A | 30303M102 | 465,558 | 1,384,146 | SH | DFND | 1 | 1,384,146 | 0 | 0 | |
MICROCHIP TECHNOLOGY INC. | COM | 595017104 | 783 | 8,994 | SH | DFND | 1 | 8,994 | 0 | 0 | |
MICRON TECHNOLOGY INC | COM | 595112103 | 239,559 | 2,571,757 | SH | DFND | 1 | 2,571,757 | 0 | 0 | |
MICROSOFT CORP | COM | 594918104 | 1,272,897 | 3,784,778 | SH | DFND | 1,2 | 3,784,778 | 0 | 0 | |
MICROSOFT CORP | COM | 594918104 | 479,256 | 1,425,000 | SH | Call | DFND | 1 | 1,425,000 | 0 | 0 |
MICROVAST HOLDINGS INC | COM | 59516C106 | 313 | 55,267 | SH | DFND | 1 | 55,267 | 0 | 0 | |
MIRATI THERAPEUTICS INC | COM | 60468T105 | 3,911 | 26,662 | SH | DFND | 1 | 26,662 | 0 | 0 | |
MKS INSTRS INC | COM | 55306N104 | 26,726 | 153,450 | SH | DFND | 1 | 153,450 | 0 | 0 | |
MODIVCARE INC | COM | 60783X104 | 52,078 | 351,191 | SH | DFND | 1 | 351,191 | 0 | 0 | |
MOHAWK INDS INC | COM | 608190104 | 11,128 | 61,084 | SH | DFND | 1 | 61,084 | 0 | 0 | |
MOLINA HEALTHCARE INC | COM | 60855R100 | 88,569 | 278,449 | SH | DFND | 1 | 278,449 | 0 | 0 | |
MONGODB INC | CL A | 60937P106 | 127,291 | 240,466 | SH | DFND | 1 | 240,466 | 0 | 0 | |
MONOLITHIC PWR SYS INC | COM | 609839105 | 61,940 | 125,555 | SH | DFND | 1 | 125,555 | 0 | 0 | |
MORGAN STANLEY | COM NEW | 617446448 | 13,516 | 137,695 | SH | DFND | 1 | 137,695 | 0 | 0 | |
MORPHIC HLDG INC | COM | 61775R105 | 15,399 | 325,000 | SH | DFND | 1 | 325,000 | 0 | 0 | |
MP MATERIALS CORP | COM CL A | 553368101 | 1,486 | 32,712 | SH | DFND | 1 | 32,712 | 0 | 0 | |
NANOSTRING TECHNOLOGIES INC | COM | 63009R109 | 49,986 | 1,183,652 | SH | DFND | 1 | 1,183,652 | 0 | 0 | |
NATERA INC | COM | 632307104 | 11,928 | 127,718 | SH | DFND | 1 | 127,718 | 0 | 0 | |
NATIONAL INSTRS CORP | COM | 636518102 | 451 | 10,326 | SH | DFND | 1 | 10,326 | 0 | 0 | |
NETEASE INC | SPONSORED ADS | 64110W102 | 572 | 5,618 | SH | DFND | 1 | 5,618 | 0 | 0 | |
NETFLIX INC | COM | 64110L106 | 190,049 | 315,466 | SH | DFND | 1 | 315,466 | 0 | 0 | |
NEUROCRINE BIOSCIENCES INC | COM | 64125C109 | 2,920 | 34,287 | SH | DFND | 1 | 34,287 | 0 | 0 | |
NEVRO CORP | COM | 64157F103 | 3,782 | 46,647 | SH | DFND | 1 | 46,647 | 0 | 0 | |
NIKOLA CORP | COM | 654110105 | 424 | 42,970 | SH | DFND | 1 | 42,970 | 0 | 0 | |
NIO INC | SPON ADS | 62914V106 | 3,011 | 95,049 | SH | DFND | 1 | 95,049 | 0 | 0 | |
NIU TECHNOLOGIES | ADS | 65481N100 | 226 | 14,029 | SH | DFND | 1 | 14,029 | 0 | 0 | |
NVIDIA CORPORATION | COM | 67066G104 | 524,220 | 1,782,396 | SH | DFND | 1 | 1,782,396 | 0 | 0 | |
NXP SEMICONDUCTORS N V | COM | N6596X109 | 1,953 | 8,575 | SH | DFND | 1 | 8,575 | 0 | 0 | |
OAK STR HEALTH INC | COM | 67181A107 | 2,833 | 85,500 | SH | DFND | 1 | 85,500 | 0 | 0 | |
OCULAR THERAPEUTIX INC | COM | 67576A100 | 263 | 37,790 | SH | DFND | 1 | 37,790 | 0 | 0 | |
OKTA INC | CL A | 679295105 | 179,088 | 798,893 | SH | DFND | 1 | 798,893 | 0 | 0 | |
OMNICELL COM | COM | 68213N109 | 1,062 | 5,887 | SH | DFND | 1 | 5,887 | 0 | 0 | |
ON SEMICONDUCTOR CORP | COM | 682189105 | 162,158 | 2,387,490 | SH | DFND | 1 | 2,387,490 | 0 | 0 | |
ONCOCYTE CORP | COM | 68235C107 | 231 | 106,422 | SH | DFND | 1 | 106,422 | 0 | 0 | |
OPTION CARE HEALTH INC | COM NEW | 68404L201 | 56,601 | 1,990,195 | SH | DFND | 1 | 1,990,195 | 0 | 0 | |
ORACLE CORP | COM | 68389X105 | 3,782 | 43,371 | SH | DFND | 2 | 43,371 | 0 | 0 | |
OREILLY AUTOMOTIVE INC | COM | 67103H107 | 2,981 | 4,221 | SH | DFND | 2 | 4,221 | 0 | 0 | |
OTONOMO TECHNOLOGIES LTD | ORDINARY SHARES | M7571L103 | 57 | 13,962 | SH | DFND | 1 | 13,962 | 0 | 0 | |
OUSTER INC | COM | 68989M103 | 94 | 18,122 | SH | DFND | 1 | 18,122 | 0 | 0 | |
OWENS & MINOR INC NEW | COM | 690732102 | 1,437 | 33,026 | SH | DFND | 1 | 33,026 | 0 | 0 | |
PACIFIC PREMIER BANCORP | COM | 69478X105 | 6,927 | 173,053 | SH | DFND | 1 | 173,053 | 0 | 0 | |
PACIRA BIOSCIENCES INC | COM | 695127100 | 1,045 | 17,368 | SH | DFND | 1 | 17,368 | 0 | 0 | |
PACWEST BANCORP DEL | COM | 695263103 | 10,568 | 233,964 | SH | DFND | 1 | 233,964 | 0 | 0 | |
PALO ALTO NETWORKS INC | NOTE 0.375% 6/0 | 697435AF2 | 7,218 | 3,800,000 | SH | DFND | 1 | 3,800,000 | 0 | 0 | |
PAYCOM SOFTWARE INC | COM | 70432V102 | 18,149 | 43,713 | SH | DFND | 1 | 43,713 | 0 | 0 | |
PENUMBRA INC | COM | 70975L107 | 4,463 | 15,534 | SH | DFND | 1 | 15,534 | 0 | 0 | |
PG&E CORP | UNIT 99/99/9999 | 69331C140 | 115,680 | 1,000,000 | SH | DFND | 1 | 1,000,000 | 0 | 0 | |
PHOENIX NEW MEDIA LTD | SPONSORED ADS | 71910C103 | 113 | 130,876 | SH | DFND | 1 | 130,876 | 0 | 0 | |
PINTEREST INC | CL A | 72352L106 | 16,007 | 440,357 | SH | DFND | 1 | 440,357 | 0 | 0 | |
PIONEER NAT RES CO | NOTE 0.250% 5/1 | 723787AP2 | 1,787 | 1,000,000 | SH | DFND | 1 | 1,000,000 | 0 | 0 | |
PLUG POWER INC | COM NEW | 72919P202 | 3,505 | 124,146 | SH | DFND | 1 | 124,146 | 0 | 0 | |
PNC FINL SVCS GROUP INC | COM | 693475105 | 16,240 | 80,989 | SH | DFND | 1 | 80,989 | 0 | 0 | |
POWER INTEGRATIONS INC | COM | 739276103 | 84,375 | 908,328 | SH | DFND | 1 | 908,328 | 0 | 0 | |
PROASSURANCE CORP | COM | 74267C106 | 30,360 | 1,200,000 | SH | DFND | 1 | 1,200,000 | 0 | 0 | |
PROGRESSIVE CORP | COM | 743315103 | 62,540 | 609,250 | SH | DFND | 1 | 609,250 | 0 | 0 | |
PROGYNY INC | COM | 74340E103 | 915 | 18,175 | SH | DFND | 1 | 18,175 | 0 | 0 | |
PROTAGONIST THERAPEUTICS INC | COM | 74366E102 | 10,377 | 303,429 | SH | DFND | 1 | 303,429 | 0 | 0 | |
PROTERRA INC | COM | 74374T109 | 204 | 23,055 | SH | DFND | 1 | 23,055 | 0 | 0 | |
PTC INC | COM | 69370C100 | 783 | 6,463 | SH | DFND | 1 | 6,463 | 0 | 0 | |
PURE STORAGE INC | CL A | 74624M102 | 120,911 | 3,714,635 | SH | DFND | 1 | 3,714,635 | 0 | 0 | |
QIAGEN NV | SHS NEW | N72482123 | 2,878 | 46,522 | SH | DFND | 1 | 46,522 | 0 | 0 | |
QORVO INC | COM | 74736K101 | 2,918 | 18,656 | SH | DFND | 1 | 18,656 | 0 | 0 | |
QUALCOMM INC | COM | 747525103 | 204,553 | 1,118,571 | SH | DFND | 1 | 1,118,571 | 0 | 0 | |
QUANTA SVCS INC | COM | 74762E102 | 783 | 6,829 | SH | DFND | 1 | 6,829 | 0 | 0 | |
QUANTUMSCAPE CORP | COM CL A | 74767V109 | 1,725 | 77,716 | SH | DFND | 1 | 77,716 | 0 | 0 | |
QUOTIENT LTD | SHS | G73268107 | 23,962 | 9,251,653 | SH | DFND | 1 | 9,251,653 | 0 | 0 | |
R1 RCM INC | COM | 749397105 | 14,319 | 561,737 | SH | DFND | 1 | 561,737 | 0 | 0 | |
RECRO PHARMA INC | COM | 75629F109 | 514 | 300,747 | SH | DFND | 1 | 300,747 | 0 | 0 | |
REE AUTOMOTIVE LTD | CLASS A ORD SHS | M8287R103 | 184 | 33,092 | SH | DFND | 1 | 33,092 | 0 | 0 | |
REGAL REXNORD CORPORATION | COM | 758750103 | 1,361 | 8,000 | SH | DFND | 1 | 8,000 | 0 | 0 | |
REGENERON PHARMACEUTICALS | COM | 75886F107 | 107,358 | 170,000 | SH | DFND | 1 | 170,000 | 0 | 0 | |
REINSURANCE GRP OF AMERICA I | COM NEW | 759351604 | 59,398 | 542,500 | SH | DFND | 1 | 542,500 | 0 | 0 | |
RENAISSANCERE HLDGS LTD | COM | G7496G103 | 133,830 | 790,353 | SH | DFND | 1,2 | 790,353 | 0 | 0 | |
RESIDEO TECHNOLOGIES INC | COM | 76118Y104 | 1,101 | 42,305 | SH | DFND | 1 | 42,305 | 0 | 0 | |
REVANCE THERAPEUTICS INC | COM | 761330109 | 36,878 | 2,259,700 | SH | DFND | 1 | 2,259,700 | 0 | 0 | |
RINGCENTRAL INC | NOTE 3/0 | 76680RAF4 | 7,556 | 8,000,000 | SH | DFND | 1 | 8,000,000 | 0 | 0 | |
RLI CORP | COM | 749607107 | 30,828 | 275,000 | SH | DFND | 1 | 275,000 | 0 | 0 | |
ROBLOX CORP | CL A | 771049103 | 126,472 | 1,225,977 | SH | DFND | 1 | 1,225,977 | 0 | 0 | |
ROCKWELL AUTOMATION INC | COM | 773903109 | 20,019 | 57,387 | SH | DFND | 1 | 57,387 | 0 | 0 | |
ROMEO POWER INC | COM | 776153108 | 90 | 24,669 | SH | DFND | 1 | 24,669 | 0 | 0 | |
RYAN SPECIALTY GROUP HLDGS I | CL A | 78351F107 | 17,552 | 435,000 | SH | DFND | 1 | 435,000 | 0 | 0 | |
S&P GLOBAL INC | COM | 78409V104 | 28,198 | 59,751 | SH | DFND | 1 | 59,751 | 0 | 0 | |
SALESFORCE COM INC | COM | 79466L302 | 98,662 | 388,235 | SH | DFND | 1 | 388,235 | 0 | 0 | |
SEA LTD | NOTE 0.250% 9/1 | 81141RAG5 | 12,942 | 14,000,000 | SH | DFND | 1 | 14,000,000 | 0 | 0 | |
SEA LTD | SPONSORD ADS | 81141R100 | 39,993 | 178,772 | SH | DFND | 1 | 178,772 | 0 | 0 | |
SEAGATE TECHNOLOGY HLDNGS PL | ORD SHS | G7997R103 | 265,870 | 2,353,246 | SH | DFND | 1 | 2,353,246 | 0 | 0 | |
SEAGEN INC | COM | 81181C104 | 82,981 | 536,748 | SH | DFND | 1 | 536,748 | 0 | 0 | |
SEMTECH CORP | COM | 816850101 | 449 | 5,046 | SH | DFND | 1 | 5,046 | 0 | 0 | |
SENSATA TECHNOLOGIES HLDG PL | SHS | G8060N102 | 20,396 | 330,623 | SH | DFND | 1,2 | 330,623 | 0 | 0 | |
SERVICE CORP INTL | COM | 817565104 | 28,241 | 397,823 | SH | DFND | 1 | 397,823 | 0 | 0 | |
SERVICENOW INC | COM | 81762P102 | 263,134 | 405,377 | SH | DFND | 1 | 405,377 | 0 | 0 | |
SHIFT TECHNOLOGIES INC | CL A | 82452T107 | 2,571 | 753,820 | SH | DFND | 1 | 753,820 | 0 | 0 | |
SHOALS TECHNOLOGIES GROUP IN | CL A | 82489W107 | 317 | 13,064 | SH | DFND | 1 | 13,064 | 0 | 0 | |
SHOCKWAVE MED INC | COM | 82489T104 | 412 | 2,310 | SH | DFND | 1 | 2,310 | 0 | 0 | |
SHOPIFY INC | CL A | 82509L107 | 33,235 | 24,129 | SH | DFND | 1 | 24,129 | 0 | 0 | |
SIGNATURE BK NEW YORK N Y | COM | 82669G104 | 46,843 | 144,814 | SH | DFND | 1 | 144,814 | 0 | 0 | |
SILICON LABORATORIES INC | COM | 826919102 | 650 | 3,147 | SH | DFND | 1 | 3,147 | 0 | 0 | |
SILICON LABORATORIES INC | NOTE 0.625% 6/1 | 826919AD4 | 17,477 | 9,941,000 | SH | DFND | 1 | 9,941,000 | 0 | 0 | |
SKYWORKS SOLUTIONS INC | COM | 83088M102 | 2,226 | 14,347 | SH | DFND | 1 | 14,347 | 0 | 0 | |
SLR INVESTMENT CORP | COM | 83413U100 | 5,068 | 275,000 | SH | DFND | 1 | 275,000 | 0 | 0 | |
SLR SENIOR INVESTMENT CORP | COM | 83416M105 | 310 | 22,149 | SH | DFND | 1 | 22,149 | 0 | 0 | |
SMARTSHEET INC | COM CL A | 83200N103 | 84,447 | 1,090,348 | SH | DFND | 1 | 1,090,348 | 0 | 0 | |
SMITH A O CORP | COM | 831865209 | 783 | 9,121 | SH | DFND | 1 | 9,121 | 0 | 0 | |
SNAP INC | CL A | 83304A106 | 214,551 | 4,561,998 | SH | DFND | 1 | 4,561,998 | 0 | 0 | |
SNOWFLAKE INC | CL A | 833445109 | 58,916 | 173,921 | SH | DFND | 1 | 173,921 | 0 | 0 | |
SOCIEDAD QUIMICA Y MINERA DE | SPON ADR SER B | 833635105 | 1,940 | 38,467 | SH | DFND | 1 | 38,467 | 0 | 0 | |
SOLAREDGE TECHNOLOGIES INC | COM | 83417M104 | 2,429 | 8,656 | SH | DFND | 1 | 8,656 | 0 | 0 | |
SPOTIFY TECHNOLOGY S A | SHS | L8681T102 | 29,371 | 125,499 | SH | DFND | 1 | 125,499 | 0 | 0 | |
SS&C TECHNOLOGIES HLDGS INC | COM | 78467J100 | 32,608 | 397,760 | SH | DFND | 1 | 397,760 | 0 | 0 | |
SSR MNG INC | NOTE 2.500% 4/0 | 784730AB9 | 10,647 | 8,539,000 | SH | DFND | 1 | 8,539,000 | 0 | 0 | |
STELLANTIS N.V | SHS | N82405106 | 20,107 | 954,175 | SH | DFND | 2 | 954,175 | 0 | 0 | |
STEM INC | COM | 85859N102 | 215 | 11,313 | SH | DFND | 1 | 11,313 | 0 | 0 | |
STEREOTAXIS INC | COM NEW | 85916J409 | 475 | 76,687 | SH | DFND | 1 | 76,687 | 0 | 0 | |
STERIS PLC | SHS USD | G8473T100 | 100,645 | 413,481 | SH | DFND | 1 | 413,481 | 0 | 0 | |
STITCH FIX INC | COM CL A | 860897107 | 4,464 | 235,942 | SH | DFND | 1 | 235,942 | 0 | 0 | |
STRIDE INC | NOTE 1.125% 9/0 | 86333MAA6 | 1,467 | 1,500,000 | SH | DFND | 1 | 1,500,000 | 0 | 0 | |
STRYKER CORPORATION | COM | 863667101 | 11,568 | 43,257 | SH | DFND | 1 | 43,257 | 0 | 0 | |
SUMMIT THERAPEUTICS INC | COM | 86627T108 | 16,457 | 6,117,911 | SH | DFND | 1 | 6,117,911 | 0 | 0 | |
SUNNOVA ENERGY INTL INC. | COM | 86745K104 | 245 | 8,791 | SH | DFND | 1 | 8,791 | 0 | 0 | |
SUNPOWER CORP | COM | 867652406 | 283 | 13,545 | SH | DFND | 1 | 13,545 | 0 | 0 | |
SUNRUN INC | COM | 86771W105 | 556 | 16,208 | SH | DFND | 1 | 16,208 | 0 | 0 | |
SUPERNUS PHARMACEUTICALS | NOTE 0.625% 4/0 | 868459AD0 | 13,327 | 13,453,000 | SH | DFND | 1 | 13,453,000 | 0 | 0 | |
SUPERNUS PHARMACEUTICALS INC | COM | 868459108 | 18,311 | 627,945 | SH | DFND | 1 | 627,945 | 0 | 0 | |
SURGERY PARTNERS INC | COM | 86881A100 | 26,084 | 488,369 | SH | DFND | 1 | 488,369 | 0 | 0 | |
SVB FINANCIAL GROUP | COM | 78486Q101 | 12,828 | 18,913 | SH | DFND | 1 | 18,913 | 0 | 0 | |
SYNEOS HEALTH INC | CL A | 87166B102 | 8,358 | 81,401 | SH | DFND | 1 | 81,401 | 0 | 0 | |
TAIWAN SEMICONDUCTOR MFG LTD | SPONSORED ADS | 874039100 | 12,510 | 103,983 | SH | DFND | 2 | 103,983 | 0 | 0 | |
TAKE-TWO INTERACTIVE SOFTWAR | COM | 874054109 | 7,320 | 41,191 | SH | DFND | 1 | 41,191 | 0 | 0 | |
TANDEM DIABETES CARE INC | COM NEW | 875372203 | 2,284 | 15,173 | SH | DFND | 1 | 15,173 | 0 | 0 | |
TAYLOR MORRISON HOME CORP | COM | 87724P106 | 24,186 | 691,818 | SH | DFND | 1 | 691,818 | 0 | 0 | |
TE CONNECTIVITY LTD | SHS | H84989104 | 104,087 | 645,140 | SH | DFND | 1 | 645,140 | 0 | 0 | |
TELEFLEX INCORPORATED | COM | 879369106 | 4,666 | 14,206 | SH | DFND | 1 | 14,206 | 0 | 0 | |
TENABLE HLDGS INC | COM | 88025T102 | 106,328 | 1,930,782 | SH | DFND | 1 | 1,930,782 | 0 | 0 | |
TESLA INC | COM | 88160R101 | 85,423 | 80,833 | SH | DFND | 1 | 80,833 | 0 | 0 | |
TEXAS INSTRS INC | COM | 882508104 | 1,839 | 9,759 | SH | DFND | 1 | 9,759 | 0 | 0 | |
THE LION ELECTRIC COMPANY | COMMON STOCK | 536221104 | 199 | 20,010 | SH | DFND | 1 | 20,010 | 0 | 0 | |
THERMO FISHER SCIENTIFIC INC | COM | 883556102 | 15,872 | 23,788 | SH | DFND | 1 | 23,788 | 0 | 0 | |
T-MOBILE US INC | COM | 872590104 | 34,025 | 293,371 | SH | DFND | 1 | 293,371 | 0 | 0 | |
TORONTO DOMINION BK ONT | COM NEW | 891160509 | 23,758 | 274,607 | SH | DFND | 1 | 274,607 | 0 | 0 | |
TRANE TECHNOLOGIES PLC | SHS | G8994E103 | 783 | 3,876 | SH | DFND | 1 | 3,876 | 0 | 0 | |
TRAVELERS COMPANIES INC | COM | 89417E109 | 102,077 | 652,538 | SH | DFND | 1 | 652,538 | 0 | 0 | |
TRIMBLE INC | COM | 896239100 | 1,056 | 12,113 | SH | DFND | 1 | 12,113 | 0 | 0 | |
TRIPADVISOR INC | COM | 896945201 | 123,414 | 4,527,306 | SH | DFND | 1 | 4,527,306 | 0 | 0 | |
TUSIMPLE HLDGS INC | CL A | 90089L108 | 807 | 22,498 | SH | DFND | 1 | 22,498 | 0 | 0 | |
TWILIO INC | CL A | 90138F102 | 78,010 | 296,233 | SH | DFND | 1 | 296,233 | 0 | 0 | |
TWITTER INC | COM | 90184L102 | 11,181 | 258,689 | SH | DFND | 1 | 258,689 | 0 | 0 | |
UBER TECHNOLOGIES INC | COM | 90353T100 | 87,925 | 2,096,948 | SH | DFND | 1 | 2,096,948 | 0 | 0 | |
UBS GROUP AG | SHS | H42097107 | 16,933 | 984,547 | SH | DFND | 1 | 984,547 | 0 | 0 | |
UNIQURE NV | SHS | N90064101 | 274 | 13,200 | SH | DFND | 1 | 13,200 | 0 | 0 | |
UNITED RENTALS INC | COM | 911363109 | 34,914 | 105,072 | SH | DFND | 1 | 105,072 | 0 | 0 | |
UNITED THERAPEUTICS CORP DEL | COM | 91307C102 | 113,586 | 525,667 | SH | DFND | 1 | 525,667 | 0 | 0 | |
UNITEDHEALTH GROUP INC | COM | 91324P102 | 88,021 | 175,292 | SH | DFND | 1 | 175,292 | 0 | 0 | |
UNITY SOFTWARE INC | COM | 91332U101 | 17,805 | 124,521 | SH | DFND | 1 | 124,521 | 0 | 0 | |
UPSTART HLDGS INC | COM | 91680M107 | 8,660 | 57,237 | SH | DFND | 1 | 57,237 | 0 | 0 | |
US FOODS HLDG CORP | COM | 912008109 | 31,512 | 904,733 | SH | DFND | 1 | 904,733 | 0 | 0 | |
VALENS SEMICONDUCTOR LTD | ORDINARY SHARES | M9607U115 | 80 | 10,359 | SH | DFND | 1 | 10,359 | 0 | 0 | |
VELODYNE LIDAR INC | COM | 92259F101 | 96 | 20,747 | SH | DFND | 1 | 20,747 | 0 | 0 | |
VEONEER INC | COM | 92336X109 | 420 | 11,828 | SH | DFND | 1 | 11,828 | 0 | 0 | |
VERICEL CORP | COM | 92346J108 | 674 | 17,160 | SH | DFND | 1 | 17,160 | 0 | 0 | |
VERTEX PHARMACEUTICALS INC | COM | 92532F100 | 82,350 | 375,000 | SH | DFND | 1 | 375,000 | 0 | 0 | |
VERTIV HOLDINGS CO | COM CL A | 92537N108 | 1,464 | 58,614 | SH | DFND | 1 | 58,614 | 0 | 0 | |
VICOR CORP | COM | 925815102 | 435 | 3,427 | SH | DFND | 1 | 3,427 | 0 | 0 | |
VISA INC | COM CL A | 92826C839 | 37,276 | 172,008 | SH | DFND | 1 | 172,008 | 0 | 0 | |
VISHAY INTERTECHNOLOGY INC | COM | 928298108 | 248 | 11,338 | SH | DFND | 1 | 11,338 | 0 | 0 | |
VISTEON CORP | COM NEW | 92839U206 | 662 | 5,957 | SH | DFND | 1 | 5,957 | 0 | 0 | |
VMWARE INC | CL A COM | 928563402 | 783 | 6,756 | SH | DFND | 1 | 6,756 | 0 | 0 | |
VOLTA INC | COM CL A | 92873V102 | 219 | 29,828 | SH | DFND | 1 | 29,828 | 0 | 0 | |
WEBSTER FINL CORP CONN | COM | 947890109 | 8,174 | 146,379 | SH | DFND | 1 | 146,379 | 0 | 0 | |
WELLS FARGO CO NEW | COM | 949746101 | 11,188 | 233,187 | SH | DFND | 1 | 233,187 | 0 | 0 | |
WESTERN ALLIANCE BANCORP | COM | 957638109 | 10,229 | 95,024 | SH | DFND | 1 | 95,024 | 0 | 0 | |
WESTERN DIGITAL CORP. | COM | 958102105 | 75,848 | 1,163,127 | SH | DFND | 1 | 1,163,127 | 0 | 0 | |
WORKDAY INC | CL A | 98138H101 | 112,076 | 410,264 | SH | DFND | 1 | 410,264 | 0 | 0 | |
WORKHORSE GROUP INC | COM NEW | 98138J206 | 72 | 16,473 | SH | DFND | 1 | 16,473 | 0 | 0 | |
XENON PHARMACEUTICALS INC | COM | 98420N105 | 52,734 | 1,688,044 | SH | DFND | 1 | 1,688,044 | 0 | 0 | |
XILINX INC | COM | 983919101 | 3,179 | 14,993 | SH | DFND | 1 | 14,993 | 0 | 0 | |
XL FLEET CORP | COM CL A | 9837FR100 | 49 | 14,724 | SH | DFND | 1 | 14,724 | 0 | 0 | |
XOMETRY INC | CLASS A COM | 98423F109 | 5,107 | 99,644 | SH | DFND | 1 | 99,644 | 0 | 0 | |
XOS INC | COMMON STOCK | 98423B108 | 54 | 17,204 | SH | DFND | 1 | 17,204 | 0 | 0 | |
XPENG INC | ADS | 98422D105 | 4,798 | 95,340 | SH | DFND | 1 | 95,340 | 0 | 0 | |
YANDEX N V | SHS CLASS A | N97284108 | 12,769 | 211,054 | SH | DFND | 1 | 211,054 | 0 | 0 | |
Y-MABS THERAPEUTICS INC | COM | 984241109 | 22,332 | 1,377,671 | SH | DFND | 1 | 1,377,671 | 0 | 0 | |
ZAI LAB LTD | ADR | 98887Q104 | 8,190 | 130,306 | SH | DFND | 1 | 130,306 | 0 | 0 | |
ZENDESK INC | COM | 98936J101 | 127,237 | 1,220,030 | SH | DFND | 1 | 1,220,030 | 0 | 0 | |
ZENDESK INC | NOTE 0.625% 6/1 | 98936JAD3 | 1,797 | 1,500,000 | SH | DFND | 1 | 1,500,000 | 0 | 0 | |
ZENTALIS PHARMACEUTICALS INC | COM | 98943L107 | 31,046 | 369,329 | SH | DFND | 1 | 369,329 | 0 | 0 | |
ZIMMER BIOMET HOLDINGS INC | COM | 98956P102 | 16,634 | 130,936 | SH | DFND | 1 | 130,936 | 0 | 0 | |
ZOOM VIDEO COMMUNICATIONS IN | CL A | 98980L101 | 63,368 | 344,561 | SH | DFND | 1 | 344,561 | 0 | 0 | |
ZUORA INC | COM CL A | 98983V106 | 20,936 | 1,120,764 | SH | DFND | 1 | 1,120,764 | 0 | 0 |