The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||||||
UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | ||||
VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | |||||
NAME OF ISSUER | TITLE OF CLASS | CUSIP | (x$1000) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
ABBVIE INC | COM | 00287Y109 | 50,800,003 | 314,337 | SH | DFND | 1 | 314,337 | 0 | 0 | |
ACADIA HEALTHCARE COMPANY IN | COM | 00404A109 | 88,731,329 | 1,077,883 | SH | DFND | 1 | 1,077,883 | 0 | 0 | |
ACADIA PHARMACEUTICALS INC | COM | 004225108 | 7,960,000 | 500,000 | SH | DFND | 1 | 500,000 | 0 | 0 | |
ACTIVISION BLIZZARD INC | COM | 00507V109 | 29,170,679 | 381,067 | SH | DFND | 1 | 381,067 | 0 | 0 | |
ADDUS HOMECARE CORP | COM | 006739106 | 37,797,544 | 379,913 | SH | DFND | 1 | 379,913 | 0 | 0 | |
ADICET BIO INC | COM | 007002108 | 11,298,596 | 1,263,825 | SH | DFND | 1 | 1,263,825 | 0 | 0 | |
ADVANCED MICRO DEVICES INC | COM | 007903107 | 245,288,783 | 3,787,074 | SH | DFND | 1 | 3,787,074 | 0 | 0 | |
AFFILIATED MANAGERS GROUP IN | COM | 008252108 | 20,851,289 | 131,612 | SH | DFND | 1 | 131,612 | 0 | 0 | |
AFLAC INC | COM | 001055102 | 41,365,500 | 575,000 | SH | DFND | 1 | 575,000 | 0 | 0 | |
AIR PRODS & CHEMS INC | COM | 009158106 | 5,132,529 | 16,650 | SH | DFND | 1,2 | 16,650 | 0 | 0 | |
AIR TRANS SVCS GROUP INC | NOTE 1.125%10/1 | 00922RAB1 | 20,425,100 | 19,615,000 | SH | DFND | 1 | 19,615,000 | 0 | 0 | |
AIRBNB INC | COM CL A | 009066101 | 54,607,055 | 638,679 | SH | DFND | 1 | 638,679 | 0 | 0 | |
AKAMAI TECHNOLOGIES INC | NOTE 0.125% 5/0 | 00971TAJ0 | 12,343,500 | 11,700,000 | SH | DFND | 1 | 11,700,000 | 0 | 0 | |
AKOYA BIOSCIENCES INC | COM | 00974H104 | 12,589,048 | 1,315,470 | SH | DFND | 1 | 1,315,470 | 0 | 0 | |
ALBEMARLE CORP | COM | 012653101 | 574,679 | 2,650 | SH | DFND | 1,2 | 2,650 | 0 | 0 | |
ALCON AG | ORD SHS | H01301128 | 23,769,987 | 346,754 | SH | DFND | 1 | 346,754 | 0 | 0 | |
ALIBABA GROUP HLDG LTD | SPONSORED ADS | 01609W102 | 91,454,686 | 1,038,196 | SH | DFND | 1 | 1,038,196 | 0 | 0 | |
ALKERMES PLC | SHS | G01767105 | 58,830,179 | 2,251,442 | SH | DFND | 1 | 2,251,442 | 0 | 0 | |
ALNYLAM PHARMACEUTICALS INC | COM | 02043Q107 | 70,700,875 | 297,500 | SH | DFND | 1 | 297,500 | 0 | 0 | |
ALPHABET INC | CAP STK CL C | 02079K107 | 211,982,359 | 2,389,072 | SH | DFND | 1 | 2,389,072 | 0 | 0 | |
ALPHABET INC | CAP STK CL A | 02079K305 | 186,888,168 | 2,118,193 | SH | DFND | 1 | 2,118,193 | 0 | 0 | |
AMAZON COM INC | COM | 023135106 | 102,220,524 | 1,216,911 | SH | DFND | 1 | 1,216,911 | 0 | 0 | |
AMDOCS LTD | SHS | G02602103 | 19,107,271 | 210,201 | SH | DFND | 1 | 210,201 | 0 | 0 | |
AMETEK INC | COM | 031100100 | 17,195,899 | 123,074 | SH | DFND | 1 | 123,074 | 0 | 0 | |
AMGEN INC | COM | 031162100 | 6,687,077 | 25,461 | SH | DFND | 1 | 25,461 | 0 | 0 | |
ANALOG DEVICES INC | COM | 032654105 | 72,852,448 | 444,141 | SH | DFND | 1,2 | 444,141 | 0 | 0 | |
AON PLC | SHS CL A | G0403H108 | 108,050,400 | 360,000 | SH | DFND | 1 | 360,000 | 0 | 0 | |
APELLIS PHARMACEUTICALS INC | COM | 03753U106 | 356,799 | 6,900 | SH | DFND | 1 | 6,900 | 0 | 0 | |
APPLE INC | COM | 037833100 | 537,019,790 | 4,133,147 | SH | DFND | 1 | 4,133,147 | 0 | 0 | |
APTARGROUP INC | COM | 038336103 | 14,454,891 | 131,432 | SH | DFND | 1 | 131,432 | 0 | 0 | |
APTIV PLC | SHS | G6095L109 | 586,719 | 6,300 | SH | DFND | 2 | 6,300 | 0 | 0 | |
ARCH CAP GROUP LTD | ORD | G0450A105 | 319,666,594 | 5,091,854 | SH | DFND | 1 | 5,091,854 | 0 | 0 | |
ARCUTIS BIOTHERAPEUTICS INC | COM | 03969K108 | 29,685,500 | 2,005,777 | SH | DFND | 1 | 2,005,777 | 0 | 0 | |
ARES CAPITAL CORP | COM | 04010L103 | 4,685,248 | 253,668 | SH | DFND | 1 | 253,668 | 0 | 0 | |
ARES MANAGEMENT CORPORATION | CL A COM STK | 03990B101 | 4,556,051 | 66,570 | SH | DFND | 1 | 66,570 | 0 | 0 | |
ARISTA NETWORKS INC | COM | 040413106 | 129,486,518 | 1,067,050 | SH | DFND | 1 | 1,067,050 | 0 | 0 | |
ARRAY TECHNOLOGIES INC | NOTE 1.000%12/0 | 04271TAB6 | 10,981,125 | 10,750,000 | SH | DFND | 1 | 10,750,000 | 0 | 0 | |
ARRAY TECHNOLOGIES INC | COM SHS | 04271T100 | 3,063,805 | 158,500 | SH | DFND | 1,2 | 158,500 | 0 | 0 | |
ARROWHEAD PHARMACEUTICALS IN | COM | 04280A100 | 508,906 | 12,547 | SH | DFND | 1 | 12,547 | 0 | 0 | |
ASPEN TECHNOLOGY INC | COM | 29109X106 | 1,906,523 | 9,282 | SH | DFND | 1 | 9,282 | 0 | 0 | |
ATLASSIAN CORPORATION | CL A | 049468101 | 39,199,917 | 304,631 | SH | DFND | 1 | 304,631 | 0 | 0 | |
ATRICURE INC | COM | 04963C209 | 816,548 | 18,399 | SH | DFND | 1 | 18,399 | 0 | 0 | |
AVADEL PHARMACEUTICALS PLC | SPONSORED ADR | 05337M104 | 20,137,428 | 2,812,490 | SH | DFND | 1 | 2,812,490 | 0 | 0 | |
AVANTOR INC | COM | 05352A100 | 44,307,580 | 2,100,881 | SH | DFND | 1 | 2,100,881 | 0 | 0 | |
AXON ENTERPRISE INC | COM | 05464C101 | 6,131,114 | 36,950 | SH | DFND | 1 | 36,950 | 0 | 0 | |
AXONICS INC | COM | 05465P101 | 44,417,310 | 710,336 | SH | DFND | 1 | 710,336 | 0 | 0 | |
AZENTA INC | COM | 114340102 | 322,539 | 5,540 | SH | DFND | 1 | 5,540 | 0 | 0 | |
BAKER HUGHES COMPANY | CL A | 05722G100 | 11,460,563 | 388,099 | SH | DFND | 1 | 388,099 | 0 | 0 | |
BANK AMERICA CORP | COM | 060505104 | 27,170,224 | 820,357 | SH | DFND | 1 | 820,357 | 0 | 0 | |
BANK OF NT BUTTERFIELD&SON L | SHS NEW | G0772R208 | 4,553,984 | 152,767 | SH | DFND | 1 | 152,767 | 0 | 0 | |
BECTON DICKINSON & CO | COM | 075887109 | 62,961,120 | 247,586 | SH | DFND | 1 | 247,586 | 0 | 0 | |
BELLUS HEALTH INC NEW | COM NEW | 07987C204 | 24,965,990 | 3,037,225 | SH | DFND | 1 | 3,037,225 | 0 | 0 | |
BENTLEY SYS INC | NOTE 0.375% 7/0 | 08265TAD1 | 6,142,500 | 7,500,000 | SH | DFND | 1 | 7,500,000 | 0 | 0 | |
BERKLEY W R CORP | COM | 084423102 | 136,975,875 | 1,887,500 | SH | DFND | 1 | 1,887,500 | 0 | 0 | |
BERKSHIRE HATHAWAY INC DEL | CL B NEW | 084670702 | 98,768,304 | 319,742 | SH | DFND | 1 | 319,742 | 0 | 0 | |
BICYCLE THERAPEUTICS PLC | SPONSORED ADS | 088786108 | 22,200,000 | 750,000 | SH | DFND | 1 | 750,000 | 0 | 0 | |
BILL COM HLDGS INC | COM | 090043100 | 62,271,076 | 571,504 | SH | DFND | 1 | 571,504 | 0 | 0 | |
BIO RAD LABS INC | CL A | 090572207 | 46,272,402 | 110,044 | SH | DFND | 1 | 110,044 | 0 | 0 | |
BIOGEN INC | COM | 09062X103 | 41,538,000 | 150,000 | SH | DFND | 1 | 150,000 | 0 | 0 | |
BIOMARIN PHARMACEUTICAL INC | COM | 09061G101 | 18,110,750 | 175,000 | SH | DFND | 1 | 175,000 | 0 | 0 | |
BIOMARIN PHARMACEUTICAL INC | NOTE 0.599% 8/0 | 09061GAH4 | 18,297,360 | 17,200,000 | SH | DFND | 1 | 17,200,000 | 0 | 0 | |
BIOMEA FUSION INC | COM | 09077A106 | 4,215,000 | 500,000 | SH | DFND | 1 | 500,000 | 0 | 0 | |
BLACKLINE INC | NOTE 3/1 | 09239BAD1 | 31,275,938 | 36,500,000 | SH | DFND | 1 | 36,500,000 | 0 | 0 | |
BLOCK INC | CL A | 852234103 | 49,432,960 | 786,648 | SH | DFND | 1 | 786,648 | 0 | 0 | |
BLOOMIN BRANDS INC | NOTE 5.000% 5/0 | 094235AB4 | 3,655,000 | 2,000,000 | SH | DFND | 1 | 2,000,000 | 0 | 0 | |
BOOKING HOLDINGS INC | COM | 09857L108 | 15,846,147 | 7,863 | SH | DFND | 1 | 7,863 | 0 | 0 | |
BOOKING HOLDINGS INC | NOTE 0.750% 5/0 | 09857LAN8 | 6,684,520 | 5,000,000 | SH | DFND | 1 | 5,000,000 | 0 | 0 | |
BOSTON SCIENTIFIC CORP | COM | 101137107 | 102,440,993 | 2,213,983 | SH | DFND | 1 | 2,213,983 | 0 | 0 | |
BRAZE INC | COM CL A | 10576N102 | 3,295,806 | 120,814 | SH | DFND | 1 | 120,814 | 0 | 0 | |
BRUKER CORP | COM | 116794108 | 305,866 | 4,475 | SH | DFND | 1 | 4,475 | 0 | 0 | |
CANADIAN NAT RES LTD | COM | 136385101 | 21,922,133 | 394,780 | SH | DFND | 1 | 394,780 | 0 | 0 | |
CANNAE HLDGS INC | COM | 13765N107 | 15,574,519 | 754,214 | SH | DFND | 1 | 754,214 | 0 | 0 | |
CASTLE BIOSCIENCES INC | COM | 14843C105 | 315,389 | 13,398 | SH | DFND | 1 | 13,398 | 0 | 0 | |
CELLDEX THERAPEUTICS INC NEW | COM NEW | 15117B202 | 69,083,500 | 1,550,000 | SH | DFND | 1 | 1,550,000 | 0 | 0 | |
CENOVUS ENERGY INC | COM | 15135U109 | 22,375,769 | 1,138,716 | SH | DFND | 1 | 1,138,716 | 0 | 0 | |
CENTENE CORP DEL | COM | 15135B101 | 21,348,597 | 260,317 | SH | DFND | 1 | 260,317 | 0 | 0 | |
CEREVEL THERAPEUTICS HLDNG I | COM | 15678U128 | 14,865,275 | 471,315 | SH | DFND | 1 | 471,315 | 0 | 0 | |
CERIDIAN HCM HLDG INC | NOTE 0.250% 3/1 | 15677JAD0 | 11,459,500 | 13,000,000 | SH | DFND | 1 | 13,000,000 | 0 | 0 | |
CERUS CORP | COM | 157085101 | 7,421,676 | 2,033,336 | SH | DFND | 1 | 2,033,336 | 0 | 0 | |
CHART INDS INC | 6.75DP CNV PFD B | 16115Q407 | 3,798,000 | 75,000 | SH | DFND | 1 | 75,000 | 0 | 0 | |
CHEGG INC | NOTE 9/0 | 163092AF6 | 15,888,000 | 20,000,000 | SH | DFND | 1 | 20,000,000 | 0 | 0 | |
CHEMED CORP NEW | COM | 16359R103 | 5,359,515 | 10,500 | SH | DFND | 1 | 10,500 | 0 | 0 | |
CHUBB LIMITED | COM | H1467J104 | 242,841,113 | 1,100,821 | SH | DFND | 1 | 1,100,821 | 0 | 0 | |
CITIZENS FINL GROUP INC | COM | 174610105 | 8,491,243 | 215,678 | SH | DFND | 1 | 215,678 | 0 | 0 | |
CLOUDFLARE INC | CL A COM | 18915M107 | 61,284,687 | 1,355,556 | SH | DFND | 1 | 1,355,556 | 0 | 0 | |
CLOUDFLARE INC | NOTE 8/1 | 18915MAC1 | 29,110,000 | 35,500,000 | SH | DFND | 1 | 35,500,000 | 0 | 0 | |
COGNEX CORP | COM | 192422103 | 7,878,724 | 167,241 | SH | DFND | 1,2 | 167,241 | 0 | 0 | |
COMERICA INC | COM | 200340107 | 4,174,315 | 62,443 | SH | DFND | 1 | 62,443 | 0 | 0 | |
CONFLUENT INC | CLASS A COM | 20717M103 | 16,064,352 | 722,318 | SH | DFND | 1 | 722,318 | 0 | 0 | |
COUPA SOFTWARE INC | NOTE 0.125% 6/1 | 22266LAC0 | 27,682,050 | 28,500,000 | SH | DFND | 1 | 28,500,000 | 0 | 0 | |
CROWDSTRIKE HLDGS INC | CL A | 22788C105 | 89,352,779 | 848,635 | SH | DFND | 1 | 848,635 | 0 | 0 | |
CULLEN FROST BANKERS INC | COM | 229899109 | 5,333,159 | 39,889 | SH | DFND | 1 | 39,889 | 0 | 0 | |
CYBERARK SOFTWARE LTD | SHS | M2682V108 | 96,009,326 | 740,527 | SH | DFND | 1 | 740,527 | 0 | 0 | |
CYTOKINETICS INC | COM NEW | 23282W605 | 124,849,282 | 2,724,777 | SH | DFND | 1 | 2,724,777 | 0 | 0 | |
DATADOG INC | CL A COM | 23804L103 | 5,732,706 | 77,996 | SH | DFND | 1 | 77,996 | 0 | 0 | |
DATADOG INC | NOTE 0.125% 6/1 | 23804LAB9 | 4,604,250 | 4,200,000 | SH | DFND | 1 | 4,200,000 | 0 | 0 | |
DAY ONE BIOPHARMACEUTICALS I | COM | 23954D109 | 30,118,273 | 1,399,548 | SH | DFND | 1 | 1,399,548 | 0 | 0 | |
DECIPHERA PHARMACEUTICALS IN | COM | 24344T101 | 20,487,500 | 1,250,000 | SH | DFND | 1 | 1,250,000 | 0 | 0 | |
DEERE & CO | COM | 244199105 | 5,940,041 | 13,854 | SH | DFND | 1 | 13,854 | 0 | 0 | |
DEXCOM INC | COM | 252131107 | 72,515,046 | 640,366 | SH | DFND | 1 | 640,366 | 0 | 0 | |
DEXCOM INC | NOTE 0.250%11/1 | 252131AK3 | 1,638,750 | 1,500,000 | SH | DFND | 1 | 1,500,000 | 0 | 0 | |
DROPBOX INC | NOTE 3/0 | 26210CAD6 | 8,960,000 | 10,000,000 | SH | DFND | 1 | 10,000,000 | 0 | 0 | |
EAST WEST BANCORP INC | COM | 27579R104 | 5,263,565 | 79,872 | SH | DFND | 1 | 79,872 | 0 | 0 | |
EDWARDS LIFESCIENCES CORP | COM | 28176E108 | 5,675,060 | 76,063 | SH | DFND | 1 | 76,063 | 0 | 0 | |
ELASTIC N V | ORD SHS | N14506104 | 56,323,130 | 1,093,653 | SH | DFND | 1 | 1,093,653 | 0 | 0 | |
ELEVANCE HEALTH INC | COM | 036752103 | 20,691,158 | 40,336 | SH | DFND | 1 | 40,336 | 0 | 0 | |
EMERSON ELEC CO | COM | 291011104 | 14,551,841 | 151,487 | SH | DFND | 1 | 151,487 | 0 | 0 | |
ENCORE CAP EUROPE FIN LTD | NOTE 4.500% 9/0 | 29260UAA5 | 2,664,000 | 2,250,000 | SH | DFND | 1 | 2,250,000 | 0 | 0 | |
ENERSYS | COM | 29275Y102 | 2,325,960 | 31,500 | SH | DFND | 1,2 | 31,500 | 0 | 0 | |
ENPHASE ENERGY INC | COM | 29355A107 | 64,339,177 | 242,826 | SH | DFND | 1,2 | 242,826 | 0 | 0 | |
ENTERPRISE FINL SVCS CORP | COM | 293712105 | 5,254,289 | 107,318 | SH | DFND | 1 | 107,318 | 0 | 0 | |
ENVISTA HOLDINGS CORPORATION | COM | 29415F104 | 7,786,423 | 231,257 | SH | DFND | 1 | 231,257 | 0 | 0 | |
ESQUIRE FINL HLDGS INC | COM | 29667J101 | 537,981 | 12,436 | SH | DFND | 1 | 12,436 | 0 | 0 | |
ESSENT GROUP LTD | COM | G3198U102 | 125,874,000 | 3,237,500 | SH | DFND | 1 | 3,237,500 | 0 | 0 | |
ETSY INC | NOTE 0.125%10/0 | 29786AAJ5 | 5,733,150 | 3,700,000 | SH | DFND | 1 | 3,700,000 | 0 | 0 | |
EVEREST RE GROUP LTD | COM | G3223R108 | 96,068,300 | 290,000 | SH | DFND | 1 | 290,000 | 0 | 0 | |
EVOLENT HEALTH INC | CL A | 30050B101 | 1,310,578 | 46,673 | SH | DFND | 1 | 46,673 | 0 | 0 | |
EXACT SCIENCES CORP | COM | 30063P105 | 214,626 | 4,335 | SH | DFND | 1 | 4,335 | 0 | 0 | |
EXELIXIS INC | COM | 30161Q104 | 41,237,204 | 2,570,898 | SH | DFND | 1 | 2,570,898 | 0 | 0 | |
FARFETCH LTD | ORD SH CL A | 30744W107 | 3,477,983 | 735,303 | SH | DFND | 1 | 735,303 | 0 | 0 | |
FERGUSON PLC NEW | SHS | G3421J106 | 25,173,707 | 198,265 | SH | DFND | 1 | 198,265 | 0 | 0 | |
FIRST AMERN FINL CORP | COM | 31847R102 | 54,957,000 | 1,050,000 | SH | DFND | 1 | 1,050,000 | 0 | 0 | |
FIRST REP BK SAN FRANCISCO C | COM | 33616C100 | 15,778,782 | 129,451 | SH | DFND | 1 | 129,451 | 0 | 0 | |
FIRST SOLAR INC | COM | 336433107 | 26,857,347 | 179,300 | SH | DFND | 1,2 | 179,300 | 0 | 0 | |
FISERV INC | COM | 337738108 | 19,834,482 | 196,245 | SH | DFND | 1 | 196,245 | 0 | 0 | |
FLYWIRE CORPORATION | COM VTG | 302492103 | 15,426,035 | 630,406 | SH | DFND | 1 | 630,406 | 0 | 0 | |
FRESHWORKS INC | CLASS A COM | 358054104 | 42,565,327 | 2,893,632 | SH | DFND | 1 | 2,893,632 | 0 | 0 | |
GITLAB INC | CLASS A COM | 37637K108 | 68,160,227 | 1,500,005 | SH | DFND | 1 | 1,500,005 | 0 | 0 | |
GLOBANT S A | COM | L44385109 | 50,829,387 | 302,268 | SH | DFND | 1 | 302,268 | 0 | 0 | |
GLOBUS MED INC | CL A | 379577208 | 53,730,929 | 723,454 | SH | DFND | 1 | 723,454 | 0 | 0 | |
GOLUB CAP BDC INC | COM | 38173M102 | 3,730,005 | 283,435 | SH | DFND | 1 | 283,435 | 0 | 0 | |
GUARDANT HEALTH INC | NOTE 11/1 | 40131MAB5 | 11,440,925 | 18,250,000 | SH | DFND | 1 | 18,250,000 | 0 | 0 | |
H WORLD GROUP LTD | SPONSORED ADS | 44332N106 | 479,176 | 11,296 | SH | DFND | 1 | 11,296 | 0 | 0 | |
H WORLD GROUP LTD | NOTE 3.000% 5/0 | 44332NAB2 | 6,127,500 | 5,000,000 | SH | DFND | 1 | 5,000,000 | 0 | 0 | |
HAGERTY INC | CL A COM | 405166109 | 38,066,831 | 4,526,377 | SH | DFND | 1 | 4,526,377 | 0 | 0 | |
HALOZYME THERAPEUTICS INC | NOTE 0.250% 3/0 | 40637HAD1 | 2,432,813 | 2,500,000 | SH | DFND | 1 | 2,500,000 | 0 | 0 | |
HARMONY BIOSCIENCES HLDGS IN | COM | 413197104 | 29,441,308 | 534,325 | SH | DFND | 1 | 534,325 | 0 | 0 | |
HASHICORP INC | COM CL A | 418100103 | 4,522,009 | 165,399 | SH | DFND | 1 | 165,399 | 0 | 0 | |
HCA HEALTHCARE INC | COM | 40412C101 | 20,219,989 | 84,264 | SH | DFND | 1 | 84,264 | 0 | 0 | |
HEALTH CATALYST INC | COM | 42225T107 | 283,183 | 26,640 | SH | DFND | 1 | 26,640 | 0 | 0 | |
HUBSPOT INC | COM | 443573100 | 130,193,215 | 450,293 | SH | DFND | 1 | 450,293 | 0 | 0 | |
HUMANA INC | COM | 444859102 | 11,426,447 | 22,309 | SH | DFND | 1 | 22,309 | 0 | 0 | |
ICON PLC | SHS | G4705A100 | 17,186,075 | 88,474 | SH | DFND | 1 | 88,474 | 0 | 0 | |
IMPINJ INC | COM | 453204109 | 5,264,878 | 48,222 | SH | DFND | 1 | 48,222 | 0 | 0 | |
INCYTE CORP | COM | 45337C102 | 99,200,983 | 1,235,072 | SH | DFND | 1 | 1,235,072 | 0 | 0 | |
INFINITY PHARMACEUTICALS INC | COM | 45665G303 | 1,149,539 | 2,071,242 | SH | DFND | 1 | 2,071,242 | 0 | 0 | |
INSMED INC | COM PAR $.01 | 457669307 | 30,796,153 | 1,541,349 | SH | DFND | 1 | 1,541,349 | 0 | 0 | |
INSULET CORP | COM | 45784P101 | 3,711,080 | 12,606 | SH | DFND | 1 | 12,606 | 0 | 0 | |
INTERCONTINENTAL EXCHANGE IN | COM | 45866F104 | 20,882,605 | 203,554 | SH | DFND | 1 | 203,554 | 0 | 0 | |
INTRA-CELLULAR THERAPIES INC | COM | 46116X101 | 23,738,854 | 448,580 | SH | DFND | 1 | 448,580 | 0 | 0 | |
INTUIT | COM | 461202103 | 15,874,727 | 40,786 | SH | DFND | 1 | 40,786 | 0 | 0 | |
INTUITIVE SURGICAL INC | COM NEW | 46120E602 | 68,357,079 | 257,611 | SH | DFND | 1 | 257,611 | 0 | 0 | |
IRHYTHM TECHNOLOGIES INC | COM | 450056106 | 538,603 | 5,750 | SH | DFND | 1 | 5,750 | 0 | 0 | |
ITRON INC | COM | 465741106 | 3,190,950 | 63,000 | SH | DFND | 1,2 | 63,000 | 0 | 0 | |
IVERIC BIO INC | COM | 46583P102 | 40,007,325 | 1,868,628 | SH | DFND | 1 | 1,868,628 | 0 | 0 | |
JAMES RIV GROUP LTD | COM | G5005R107 | 24,569,250 | 1,175,000 | SH | DFND | 1 | 1,175,000 | 0 | 0 | |
JD.COM INC | SPON ADR CL A | 47215P106 | 483,055 | 8,606 | SH | DFND | 1 | 8,606 | 0 | 0 | |
JOHNSON & JOHNSON | COM | 478160104 | 63,803,507 | 361,186 | SH | DFND | 1 | 361,186 | 0 | 0 | |
JPMORGAN CHASE & CO | COM | 46625H100 | 34,325,979 | 255,973 | SH | DFND | 1 | 255,973 | 0 | 0 | |
KE HLDGS INC | SPONSORED ADS | 482497104 | 260,508 | 18,661 | SH | DFND | 1 | 18,661 | 0 | 0 | |
KLA CORP | COM NEW | 482480100 | 160,267,158 | 425,078 | SH | DFND | 1 | 425,078 | 0 | 0 | |
KORNIT DIGITAL LTD | SHS | M6372Q113 | 20,606,203 | 897,092 | SH | DFND | 1 | 897,092 | 0 | 0 | |
LANTHEUS HLDGS INC | COM | 516544103 | 757,011 | 14,855 | SH | DFND | 1 | 14,855 | 0 | 0 | |
LATTICE SEMICONDUCTOR CORP | COM | 518415104 | 129,516,765 | 1,996,251 | SH | DFND | 1,2 | 1,996,251 | 0 | 0 | |
LEGEND BIOTECH CORP | SPONSORED ADS | 52490G102 | 52,958,481 | 1,060,867 | SH | DFND | 1 | 1,060,867 | 0 | 0 | |
LIBERTY MEDIA CORP DEL | COM SER C FRMLA | 531229854 | 8,980,570 | 150,227 | SH | DFND | 1 | 150,227 | 0 | 0 | |
LILLY ELI & CO | COM | 532457108 | 55,627,070 | 152,053 | SH | DFND | 1 | 152,053 | 0 | 0 | |
LINDE PLC | SHS | G5494J103 | 24,732,925 | 75,826 | SH | DFND | 1,2 | 75,826 | 0 | 0 | |
LITTELFUSE INC | COM | 537008104 | 8,300,219 | 37,694 | SH | DFND | 1 | 37,694 | 0 | 0 | |
LIVANOVA PLC | SHS | G5509L101 | 38,422,516 | 691,799 | SH | DFND | 1 | 691,799 | 0 | 0 | |
LIVENT CORP | COM | 53814L108 | 366,602 | 18,450 | SH | DFND | 1,2 | 18,450 | 0 | 0 | |
LPL FINL HLDGS INC | COM | 50212V100 | 10,469,762 | 48,433 | SH | DFND | 1 | 48,433 | 0 | 0 | |
MACOM TECH SOLUTIONS HLDGS I | NOTE 0.250% 3/1 | 55405YAB6 | 3,978,000 | 4,000,000 | SH | DFND | 1 | 4,000,000 | 0 | 0 | |
MARKEL CORP | COM | 570535104 | 167,979,975 | 127,500 | SH | DFND | 1 | 127,500 | 0 | 0 | |
MARRIOTT VACATIONS WORLDWIDE | NOTE 1/1 | 57164YAD9 | 3,430,000 | 3,500,000 | SH | DFND | 1 | 3,500,000 | 0 | 0 | |
MARSH & MCLENNAN COS INC | COM | 571748102 | 220,467,349 | 1,332,290 | SH | DFND | 1 | 1,332,290 | 0 | 0 | |
MARVELL TECHNOLOGY INC | COM | 573874104 | 94,213,351 | 2,543,557 | SH | DFND | 1,2 | 2,543,557 | 0 | 0 | |
MASTERCARD INCORPORATED | CL A | 57636Q104 | 116,406,095 | 334,760 | SH | DFND | 1 | 334,760 | 0 | 0 | |
MAXEON SOLAR TECHNOLOGIES LT | SHS | Y58473102 | 754,820 | 47,000 | SH | DFND | 1,2 | 47,000 | 0 | 0 | |
MERCADOLIBRE INC | COM | 58733R102 | 91,041,884 | 107,584 | SH | DFND | 1 | 107,584 | 0 | 0 | |
MERIT MED SYS INC | COM | 589889104 | 39,776,786 | 563,251 | SH | DFND | 1 | 563,251 | 0 | 0 | |
MERUS N V | COM | N5749R100 | 11,602,500 | 750,000 | SH | DFND | 1 | 750,000 | 0 | 0 | |
META PLATFORMS INC | CL A | 30303M102 | 58,423,385 | 485,486 | SH | DFND | 1 | 485,486 | 0 | 0 | |
MICRON TECHNOLOGY INC | COM | 595112103 | 8,413,583 | 168,339 | SH | DFND | 1 | 168,339 | 0 | 0 | |
MICROSOFT CORP | COM | 594918104 | 724,694,311 | 3,021,826 | SH | DFND | 1 | 3,021,826 | 0 | 0 | |
MIDDLEBY CORP | NOTE 1.000% 9/0 | 596278AB7 | 1,770,750 | 1,500,000 | SH | DFND | 1 | 1,500,000 | 0 | 0 | |
MIRUM PHARMACEUTICALS INC | COM | 604749101 | 16,670,687 | 854,907 | SH | DFND | 1 | 854,907 | 0 | 0 | |
MKS INSTRS INC | COM | 55306N104 | 9,537,802 | 112,567 | SH | DFND | 1 | 112,567 | 0 | 0 | |
MOLINA HEALTHCARE INC | COM | 60855R100 | 66,679,013 | 201,923 | SH | DFND | 1 | 201,923 | 0 | 0 | |
MONGODB INC | CL A | 60937P106 | 51,329,179 | 260,766 | SH | DFND | 1 | 260,766 | 0 | 0 | |
MONOLITHIC PWR SYS INC | COM | 609839105 | 105,064,603 | 297,120 | SH | DFND | 1,2 | 297,120 | 0 | 0 | |
MOONLAKE IMMUNOTHERAPEUTICS | CLASS A ORD | 61559X104 | 9,201,959 | 876,377 | SH | DFND | 1 | 876,377 | 0 | 0 | |
MORGAN STANLEY | COM NEW | 617446448 | 8,529,036 | 100,318 | SH | DFND | 1 | 100,318 | 0 | 0 | |
MORPHIC HLDG INC | COM | 61775R105 | 8,693,750 | 325,000 | SH | DFND | 1 | 325,000 | 0 | 0 | |
MP MATERIALS CORP | COM CL A | 553368101 | 6,968,360 | 287,000 | SH | DFND | 1,2 | 287,000 | 0 | 0 | |
MSCI INC | COM | 55354G100 | 11,425,040 | 24,561 | SH | DFND | 1 | 24,561 | 0 | 0 | |
NANOSTRING TECHNOLOGIES INC | COM | 63009R109 | 30,116,486 | 3,778,731 | SH | DFND | 1 | 3,778,731 | 0 | 0 | |
NATERA INC | COM | 632307104 | 1,013,007 | 25,218 | SH | DFND | 1 | 25,218 | 0 | 0 | |
NCL CORP LTD | NOTE 5.375% 8/0 | 62886HAX9 | 5,776,950 | 5,700,000 | SH | DFND | 1 | 5,700,000 | 0 | 0 | |
NETEASE INC | SPONSORED ADS | 64110W102 | 273,670 | 3,768 | SH | DFND | 1 | 3,768 | 0 | 0 | |
NEUROCRINE BIOSCIENCES INC | COM | 64125C109 | 20,776,110 | 173,946 | SH | DFND | 1 | 173,946 | 0 | 0 | |
NORFOLK SOUTHN CORP | COM | 655844108 | 15,026,938 | 60,981 | SH | DFND | 1 | 60,981 | 0 | 0 | |
NUTANIX INC | NOTE 0.250%10/0 | 67059NAH1 | 30,302,415 | 36,010,000 | SH | DFND | 1 | 36,010,000 | 0 | 0 | |
NVIDIA CORPORATION | COM | 67066G104 | 189,483,955 | 1,296,592 | SH | DFND | 1 | 1,296,592 | 0 | 0 | |
NXP SEMICONDUCTORS N V | COM | N6596X109 | 521,499 | 3,300 | SH | DFND | 2 | 3,300 | 0 | 0 | |
OMNICELL COM | COM | 68213N109 | 672,704 | 13,342 | SH | DFND | 1 | 13,342 | 0 | 0 | |
ON SEMICONDUCTOR CORP | COM | 682189105 | 38,765,325 | 621,538 | SH | DFND | 1,2 | 621,538 | 0 | 0 | |
OPTION CARE HEALTH INC | COM NEW | 68404L201 | 69,487,168 | 2,309,311 | SH | DFND | 1 | 2,309,311 | 0 | 0 | |
ORGANON & CO | COMMON STOCK | 68622V106 | 588,150 | 21,058 | SH | DFND | 1 | 21,058 | 0 | 0 | |
OVINTIV INC | COM | 69047Q102 | 23,629,947 | 465,982 | SH | DFND | 1 | 465,982 | 0 | 0 | |
PACIRA BIOSCIENCES INC | COM | 695127100 | 486,293 | 12,595 | SH | DFND | 1 | 12,595 | 0 | 0 | |
PALO ALTO NETWORKS INC | COM | 697435105 | 81,176,697 | 581,745 | SH | DFND | 1 | 581,745 | 0 | 0 | |
PAYCOM SOFTWARE INC | COM | 70432V102 | 6,107,832 | 19,683 | SH | DFND | 1 | 19,683 | 0 | 0 | |
PAYPAL HLDGS INC | COM | 70450Y103 | 278,969 | 3,917 | SH | DFND | 1 | 3,917 | 0 | 0 | |
PENUMBRA INC | COM | 70975L107 | 79,398,866 | 356,913 | SH | DFND | 1 | 356,913 | 0 | 0 | |
PINTEREST INC | CL A | 72352L106 | 54,976,111 | 2,264,255 | SH | DFND | 1 | 2,264,255 | 0 | 0 | |
PLIANT THERAPEUTICS INC | COM | 729139105 | 31,569,060 | 1,633,164 | SH | DFND | 1 | 1,633,164 | 0 | 0 | |
PLUG POWER INC | COM NEW | 72919P202 | 2,894,580 | 234,000 | SH | DFND | 1,2 | 234,000 | 0 | 0 | |
PNC FINL SVCS GROUP INC | COM | 693475105 | 13,800,165 | 87,376 | SH | DFND | 1 | 87,376 | 0 | 0 | |
POWER INTEGRATIONS INC | COM | 739276103 | 34,488,785 | 480,881 | SH | DFND | 1,2 | 480,881 | 0 | 0 | |
PRIVIA HEALTH GROUP INC | COM | 74276R102 | 585,123 | 25,765 | SH | DFND | 1 | 25,765 | 0 | 0 | |
PROASSURANCE CORP | COM | 74267C106 | 39,307,500 | 2,250,000 | SH | DFND | 1 | 2,250,000 | 0 | 0 | |
PROGRESSIVE CORP | COM | 743315103 | 87,554,250 | 675,000 | SH | DFND | 1 | 675,000 | 0 | 0 | |
PROGYNY INC | COM | 74340E103 | 453,482 | 14,558 | SH | DFND | 1 | 14,558 | 0 | 0 | |
PURE STORAGE INC | CL A | 74624M102 | 84,420,280 | 3,154,719 | SH | DFND | 1 | 3,154,719 | 0 | 0 | |
QIAGEN NV | SHS NEW | N72482123 | 18,364,079 | 368,239 | SH | DFND | 1 | 368,239 | 0 | 0 | |
QORVO INC | COM | 74736K101 | 6,943,024 | 76,600 | SH | DFND | 1,2 | 76,600 | 0 | 0 | |
QUALCOMM INC | COM | 747525103 | 100,469,878 | 913,861 | SH | DFND | 1 | 913,861 | 0 | 0 | |
QUALTRICS INTL INC | COM CL A | 747601201 | 5,016,270 | 483,263 | SH | DFND | 1 | 483,263 | 0 | 0 | |
QUIDELORTHO CORP | COM | 219798105 | 588,981 | 6,875 | SH | DFND | 1 | 6,875 | 0 | 0 | |
R1 RCM INC | COM | 77634L105 | 9,737,901 | 889,306 | SH | DFND | 1 | 889,306 | 0 | 0 | |
REGENERON PHARMACEUTICALS | COM | 75886F107 | 84,775,075 | 117,500 | SH | DFND | 1 | 117,500 | 0 | 0 | |
REGIONS FINANCIAL CORP NEW | COM | 7591EP100 | 4,563,842 | 211,681 | SH | DFND | 1 | 211,681 | 0 | 0 | |
REINSURANCE GRP OF AMERICA I | COM NEW | 759351604 | 104,791,375 | 737,500 | SH | DFND | 1 | 737,500 | 0 | 0 | |
RENAISSANCERE HLDGS LTD | COM | G7496G103 | 202,297,805 | 1,098,072 | SH | DFND | 1 | 1,098,072 | 0 | 0 | |
REPLIGEN CORP | COM | 759916109 | 423,275 | 2,500 | SH | DFND | 1 | 2,500 | 0 | 0 | |
REVANCE THERAPEUTICS INC | COM | 761330109 | 89,505,765 | 4,848,633 | SH | DFND | 1 | 4,848,633 | 0 | 0 | |
RHYTHM PHARMACEUTICALS INC | COM | 76243J105 | 36,400,000 | 1,250,000 | SH | DFND | 1 | 1,250,000 | 0 | 0 | |
RLI CORP | COM | 749607107 | 36,755,600 | 280,000 | SH | DFND | 1 | 280,000 | 0 | 0 | |
ROBLOX CORP | CL A | 771049103 | 29,623,672 | 1,040,888 | SH | DFND | 1 | 1,040,888 | 0 | 0 | |
ROCKWELL AUTOMATION INC | COM | 773903109 | 5,076,190 | 19,708 | SH | DFND | 1 | 19,708 | 0 | 0 | |
ROYAL BK CDA SUSTAINABL | COM | 780087102 | 6,664,608 | 70,885 | SH | DFND | 1 | 70,885 | 0 | 0 | |
RYAN SPECIALTY HOLDINGS INC | CL A | 78351F107 | 57,076,250 | 1,375,000 | SH | DFND | 1 | 1,375,000 | 0 | 0 | |
S&P GLOBAL INC | COM | 78409V104 | 6,172,274 | 18,428 | SH | DFND | 1 | 18,428 | 0 | 0 | |
SABRE CORP | COM | 78573M104 | 6,435,067 | 1,041,273 | SH | DFND | 1 | 1,041,273 | 0 | 0 | |
SALESFORCE INC | COM | 79466L302 | 59,352,853 | 447,642 | SH | DFND | 1 | 447,642 | 0 | 0 | |
SANOFI | SPONSORED ADR | 80105N105 | 54,483,750 | 1,125,000 | SH | DFND | 1 | 1,125,000 | 0 | 0 | |
SAREPTA THERAPEUTICS INC | DEBT 1.250% 9/1 | 803607AC4 | 10,996,250 | 9,500,000 | SH | DFND | 1 | 9,500,000 | 0 | 0 | |
SCHWAB CHARLES CORP | COM | 808513105 | 9,572,819 | 114,975 | SH | DFND | 1 | 114,975 | 0 | 0 | |
SEA LTD | SPONSORD ADS | 81141R100 | 24,468,877 | 470,284 | SH | DFND | 1 | 470,284 | 0 | 0 | |
SEA LTD | NOTE 2.375%12/0 | 81141RAF7 | 5,131,880 | 5,200,000 | SH | DFND | 1 | 5,200,000 | 0 | 0 | |
SEAGEN INC | COM | 81181C104 | 106,101,968 | 825,632 | SH | DFND | 1 | 825,632 | 0 | 0 | |
SERVICE CORP INTL | COM | 817565104 | 12,290,672 | 177,765 | SH | DFND | 1 | 177,765 | 0 | 0 | |
SERVICENOW INC | COM | 81762P102 | 187,154,294 | 482,021 | SH | DFND | 1 | 482,021 | 0 | 0 | |
SHIFT4 PMTS INC | NOTE 12/1 | 82452JAB5 | 8,213,906 | 8,250,000 | SH | DFND | 1 | 8,250,000 | 0 | 0 | |
SHOPIFY INC | CL A | 82509L107 | 78,640,677 | 2,265,649 | SH | DFND | 1 | 2,265,649 | 0 | 0 | |
SIGNATURE BK NEW YORK N Y | COM | 82669G104 | 9,422,461 | 81,778 | SH | DFND | 1 | 81,778 | 0 | 0 | |
SILICON LABORATORIES INC | NOTE 0.625% 6/1 | 826919AD4 | 3,940,070 | 3,141,000 | SH | DFND | 1 | 3,141,000 | 0 | 0 | |
SITIME CORP | COM | 82982T106 | 51,844,492 | 510,180 | SH | DFND | 1 | 510,180 | 0 | 0 | |
SMARTSHEET INC | COM CL A | 83200N103 | 76,185,334 | 1,935,603 | SH | DFND | 1 | 1,935,603 | 0 | 0 | |
SNAP INC | NOTE 0.750% 8/0 | 83304AAB2 | 1,276,125 | 1,500,000 | SH | DFND | 1 | 1,500,000 | 0 | 0 | |
SNOWFLAKE INC | CL A | 833445109 | 69,413,647 | 483,584 | SH | DFND | 1 | 483,584 | 0 | 0 | |
SOLAREDGE TECHNOLOGIES INC | COM | 83417M104 | 70,525,449 | 248,969 | SH | DFND | 1,2 | 248,969 | 0 | 0 | |
SOLAREDGE TECHNOLOGIES INC | NOTE 9/1 | 83417MAD6 | 16,204,500 | 13,000,000 | SH | DFND | 1 | 13,000,000 | 0 | 0 | |
SOUTHWEST AIRLS CO | NOTE 1.250% 5/0 | 844741BG2 | 8,433,250 | 7,000,000 | SH | DFND | 1 | 7,000,000 | 0 | 0 | |
SS&C TECHNOLOGIES HLDGS INC | COM | 78467J100 | 18,963,167 | 364,256 | SH | DFND | 1 | 364,256 | 0 | 0 | |
SSR MNG INC | NOTE 2.500% 4/0 | 784730AB9 | 11,268,778 | 10,039,000 | SH | DFND | 1 | 10,039,000 | 0 | 0 | |
STEREOTAXIS INC | COM NEW | 85916J409 | 158,742 | 76,687 | SH | DFND | 1 | 76,687 | 0 | 0 | |
STRYKER CORPORATION | COM | 863667101 | 7,203,164 | 29,462 | SH | DFND | 1 | 29,462 | 0 | 0 | |
SUNPOWER CORP | COM | 867652406 | 2,199,660 | 122,000 | SH | DFND | 1,2 | 122,000 | 0 | 0 | |
SUNRUN INC | COM | 86771W105 | 5,572,640 | 232,000 | SH | DFND | 1,2 | 232,000 | 0 | 0 | |
SUPERNUS PHARMACEUTICALS INC | COM | 868459108 | 36,352,010 | 1,019,120 | SH | DFND | 1 | 1,019,120 | 0 | 0 | |
SURGERY PARTNERS INC | COM | 86881A100 | 405,419 | 14,552 | SH | DFND | 1 | 14,552 | 0 | 0 | |
TAKE-TWO INTERACTIVE SOFTWAR | COM | 874054109 | 1,200,098 | 11,525 | SH | DFND | 1 | 11,525 | 0 | 0 | |
TANDEM DIABETES CARE INC | COM NEW | 875372203 | 921,745 | 20,506 | SH | DFND | 1 | 20,506 | 0 | 0 | |
TE CONNECTIVITY LTD | SHS | H84989104 | 8,215,892 | 71,567 | SH | DFND | 1,2 | 71,567 | 0 | 0 | |
TECK RESOURCES LTD | CL B | 878742204 | 12,906,415 | 341,259 | SH | DFND | 1 | 341,259 | 0 | 0 | |
TENET HEALTHCARE CORP | COM NEW | 88033G407 | 10,831,038 | 221,993 | SH | DFND | 1 | 221,993 | 0 | 0 | |
TERADYNE INC | COM | 880770102 | 46,600,614 | 533,493 | SH | DFND | 1 | 533,493 | 0 | 0 | |
TESLA INC | COM | 88160R101 | 27,326,744 | 221,844 | SH | DFND | 1 | 221,844 | 0 | 0 | |
THERMO FISHER SCIENTIFIC INC | COM | 883556102 | 7,454,140 | 13,536 | SH | DFND | 1 | 13,536 | 0 | 0 | |
T-MOBILE US INC | COM | 872590104 | 25,122,720 | 179,448 | SH | DFND | 1 | 179,448 | 0 | 0 | |
TORONTO DOMINION BK ONT | COM NEW | 891160509 | 15,117,833 | 233,444 | SH | DFND | 1 | 233,444 | 0 | 0 | |
TRAVELERS COMPANIES INC | COM | 89417E109 | 133,026,592 | 709,513 | SH | DFND | 1 | 709,513 | 0 | 0 | |
TRIMBLE INC | COM | 896239100 | 404,480 | 8,000 | SH | DFND | 2 | 8,000 | 0 | 0 | |
TRIP COM GROUP LTD | ADS | 89677Q107 | 60,711,459 | 1,764,868 | SH | DFND | 1 | 1,764,868 | 0 | 0 | |
TRIPADVISOR INC | COM | 896945201 | 39,281,787 | 2,184,749 | SH | DFND | 1 | 2,184,749 | 0 | 0 | |
TRUPANION INC | COM | 898202106 | 48,718,250 | 1,025,000 | SH | DFND | 1 | 1,025,000 | 0 | 0 | |
UBER TECHNOLOGIES INC | COM | 90353T100 | 11,790,398 | 476,765 | SH | DFND | 1,2 | 476,765 | 0 | 0 | |
UBS GROUP AG | SHS | H42097107 | 11,294,773 | 626,773 | SH | DFND | 1 | 626,773 | 0 | 0 | |
UNION PAC CORP | COM | 907818108 | 13,905,786 | 67,155 | SH | DFND | 1 | 67,155 | 0 | 0 | |
UNITED RENTALS INC | COM | 911363109 | 33,204,403 | 93,423 | SH | DFND | 1 | 93,423 | 0 | 0 | |
UNITED THERAPEUTICS CORP DEL | COM | 91307C102 | 90,349,494 | 324,893 | SH | DFND | 1 | 324,893 | 0 | 0 | |
UNITEDHEALTH GROUP INC | COM | 91324P102 | 60,146,270 | 113,445 | SH | DFND | 1 | 113,445 | 0 | 0 | |
US BANCORP DEL | COM NEW | 902973304 | 10,004,701 | 229,413 | SH | DFND | 1 | 229,413 | 0 | 0 | |
US FOODS HLDG CORP | COM | 912008109 | 26,847,665 | 789,173 | SH | DFND | 1 | 789,173 | 0 | 0 | |
VAIL RESORTS INC | NOTE 1/0 | 91879QAN9 | 35,901,250 | 38,500,000 | SH | DFND | 1 | 38,500,000 | 0 | 0 | |
VEEVA SYS INC | CL A COM | 922475108 | 16,468,990 | 102,051 | SH | DFND | 1 | 102,051 | 0 | 0 | |
VERADIGM INC | COM | 01988P108 | 491,362 | 27,855 | SH | DFND | 1 | 27,855 | 0 | 0 | |
VERTEX PHARMACEUTICALS INC | COM | 92532F100 | 83,746,200 | 290,000 | SH | DFND | 1 | 290,000 | 0 | 0 | |
VERTIV HOLDINGS CO | COM CL A | 92537N108 | 7,629,110 | 558,500 | SH | DFND | 1,2 | 558,500 | 0 | 0 | |
VISA INC | COM CL A | 92826C839 | 178,884,061 | 861,013 | SH | DFND | 1 | 861,013 | 0 | 0 | |
VISTEON CORP | COM NEW | 92839U206 | 588,735 | 4,500 | SH | DFND | 2 | 4,500 | 0 | 0 | |
WALMART INC | COM | 931142103 | 8,267,208 | 58,306 | SH | DFND | 1 | 58,306 | 0 | 0 | |
WELLS FARGO CO NEW | COM | 949746101 | 21,015,536 | 508,974 | SH | DFND | 1 | 508,974 | 0 | 0 | |
WORKDAY INC | CL A | 98138H101 | 76,793,594 | 458,935 | SH | DFND | 1 | 458,935 | 0 | 0 | |
XENON PHARMACEUTICALS INC | COM | 98420N105 | 120,098,812 | 3,045,874 | SH | DFND | 1 | 3,045,874 | 0 | 0 | |
Y-MABS THERAPEUTICS INC | COM | 984241109 | 9,720,614 | 1,991,929 | SH | DFND | 1 | 1,991,929 | 0 | 0 | |
ZAI LAB LTD | ADR | 98887Q104 | 5,365,623 | 174,776 | SH | DFND | 1 | 174,776 | 0 | 0 |