E Fund Management 13F-HR Quarterly holdings report by institutional manager

The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE

OMB APPROVAL

OMB Number:		3235-0006
Expires:	Oct 31, 2018
Estimated average burden
hours per response:		23.8

COLUMN 1	COLUMN 2	COLUMN 3	COLUMN 4	COLUMN 5			COLUMN 6	COLUMN 7	COLUMN 8
			VALUE	SHRS OR	SH/	PUT/	INVESTMENT	OTHER	VOTING AUTHORITY
NAME OF ISSUER	TITLE OF CLASS	CUSIP	(x$1000)	PRN AMT	PRN	CALL	DISCRETION	MANAGER	SOLE	SHARED	NONE
Pinduoduo Inc	ADR	722304102	229,535	3,667,862	SH		DFND		3,667,862	0	0
KE Holdings Inc	ADR	482497104	80,503	4,594,952	SH		DFND		4,594,952	0	0
STAAR Surgical Co	Common Stock	852312305	51,663	732,296	SH		SOLE		732,296	0	0
Kanzhun Ltd	ADR	48553T106	40,355	2,390,698	SH		DFND		2,390,698	0	0
Full Truck Alliance Co Ltd	ADR	35969L108	39,365	6,009,876	SH		DFND		6,009,876	0	0
Apple Inc	Common Stock	037833100	34,779	251,657	SH		SOLE		251,657	0	0
Sea Ltd	ADR	81141R100	33,836	603,681	SH		SOLE		603,681	0	0
Grab Holdings Ltd	Common Stock	G4124C109	31,034	11,800,000	SH		SOLE		11,800,000	0	0
Taiwan Semiconductor Manufactu	ADR	874039100	29,481	430,000	SH		SOLE		430,000	0	0
Microsoft Corp	Common Stock	594918104	28,156	120,891	SH		SOLE		120,891	0	0
QUALCOMM Inc	Common Stock	747525103	27,669	244,904	SH		SOLE		244,904	0	0
Vipshop Holdings Ltd	ADR	92763W103	20,217	2,403,908	SH		DFND		2,403,908	0	0
Alphabet Inc	Common Stock	02079K107	19,078	198,423	SH		SOLE		198,423	0	0
Advanced Micro Devices Inc	Common Stock	007903107	18,317	289,091	SH		SOLE		289,091	0	0
Tencent Music Entertainment Gr	ADR	88034P109	16,308	4,016,687	SH		DFND		4,016,687	0	0
NIO Inc	ADR	62914V106	14,639	928,272	SH		DFND		928,272	0	0
ASML Holding NV	NY Reg Shrs	N07059210	14,063	33,858	SH		SOLE		33,858	0	0
Yum China Holdings Inc	Common Stock	98850P109	13,517	285,584	SH		DFND		285,584	0	0
Lufax Holding Ltd	ADR	54975P102	13,300	5,236,160	SH		DFND		5,236,160	0	0
Autohome Inc	ADR	05278C107	12,828	446,030	SH		DFND		446,030	0	0
TAL Education Group	ADR	874080104	10,656	2,157,210	SH		DFND		2,157,210	0	0
Trip.com Group Ltd	ADR	89677Q107	10,095	369,655	SH		DFND		369,655	0	0
Tesla Inc	Common Stock	88160R101	9,622	36,276	SH		DFND		36,276	0	0
Amazon.com Inc	Common Stock	023135106	8,939	79,103	SH		SOLE		79,103	0	0
Li Auto Inc	ADR	50202M102	8,526	370,520	SH		DFND		370,520	0	0
360 DigiTech Inc	ADR	88557W101	8,002	624,176	SH		DFND		624,176	0	0
JOYY Inc	ADR	46591M109	7,542	290,098	SH		DFND		290,098	0	0
Weibo Corp	ADR	948596101	7,366	430,755	SH		DFND		430,755	0	0
ZTO Express Cayman Inc	ADR	98980A105	6,881	286,338	SH		DFND		286,338	0	0
iQIYI Inc	ADR	46267X108	6,276	2,315,943	SH		DFND		2,315,943	0	0
NVIDIA Corp	Common Stock	67066G104	5,601	46,142	SH		SOLE		46,142	0	0
Alphabet Inc	Common Stock	02079K305	4,609	48,185	SH		SOLE		48,185	0	0
H World Group Ltd	ADR	44332N106	4,389	130,849	SH		DFND		130,849	0	0
BeiGene Ltd	ADR	07725L102	4,309	31,961	SH		DFND		31,961	0	0
Broadcom Inc	Common Stock	11135F101	3,626	8,167	SH		SOLE		8,167	0	0
iShares MSCI Global Gold Miner	ETP	46434G855	3,442	183,458	SH		SOLE		183,458	0	0
Meta Platforms Inc	Common Stock	30303M102	3,438	25,336	SH		SOLE		25,336	0	0
XPeng Inc	ADR	98422D105	3,429	286,966	SH		DFND		286,966	0	0
Vertex Pharmaceuticals Inc	Common Stock	92532F100	3,373	11,648	SH		DFND		11,648	0	0
Cisco Systems Inc	Common Stock	17275R102	3,355	83,866	SH		SOLE		83,866	0	0
SPDR Gold MiniShares Trust	ETP	98149E303	3,339	101,236	SH		SOLE		101,236	0	0
iShares Gold Trust	ETP	464285204	3,337	105,848	SH		SOLE		105,848	0	0
Zhihu Inc	ADR	98955N108	3,184	3,003,800	SH		SOLE		3,003,800	0	0
United States Brent Oil Fund L	ETP	91167Q100	2,978	108,999	SH		SOLE		108,999	0	0
Visa Inc	Common Stock	92826C839	2,949	16,601	SH		SOLE		16,601	0	0
Invesco DB Oil Fund	ETP	46140H403	2,947	194,142	SH		SOLE		194,142	0	0
Texas Instruments Inc	Common Stock	882508104	2,866	18,515	SH		SOLE		18,515	0	0
United States Oil Fund LP	ETP	91232N207	2,784	42,648	SH		SOLE		42,648	0	0
PepsiCo Inc	Common Stock	713448108	2,742	16,796	SH		SOLE		16,796	0	0
Adobe Inc	Common Stock	00724F101	2,599	9,444	SH		SOLE		9,444	0	0
Costco Wholesale Corp	Common Stock	22160K105	2,543	5,385	SH		SOLE		5,385	0	0
Mastercard Inc	Common Stock	57636Q104	2,463	8,663	SH		SOLE		8,663	0	0
Lululemon Athletica Inc	Common Stock	550021109	2,392	8,555	SH		SOLE		8,555	0	0
Intuit Inc	Common Stock	461202103	2,196	5,671	SH		SOLE		5,671	0	0
Daqo New Energy Corp	ADR	23703Q203	2,149	40,481	SH		DFND		40,481	0	0
Intel Corp	Common Stock	458140100	2,142	83,126	SH		SOLE		83,126	0	0
SPDR Gold Shares	ETP	78463V107	2,087	13,492	SH		SOLE		13,492	0	0
Zai Lab Ltd	ADR	98887Q104	2,038	59,590	SH		DFND		59,590	0	0
Amgen Inc	Common Stock	031162100	2,003	8,886	SH		SOLE		8,886	0	0
PayPal Holdings Inc	Common Stock	70450Y103	2,001	23,251	SH		SOLE		23,251	0	0
Estee Lauder Cos Inc/The	Common Stock	518439104	1,948	9,021	SH		SOLE		9,021	0	0
JinkoSolar Holding Co Ltd	ADR	47759T100	1,939	35,000	SH		DFND		35,000	0	0
Automatic Data Processing Inc	Common Stock	053015103	1,897	8,388	SH		SOLE		8,388	0	0
T-Mobile US Inc	Common Stock	872590104	1,842	13,730	SH		SOLE		13,730	0	0
Wolfspeed Inc	Common Stock	977852102	1,751	16,941	SH		SOLE		16,941	0	0
Accenture PLC	Common Stock	G1151C101	1,646	6,397	SH		SOLE		6,397	0	0
Comcast Corp	Common Stock	20030N101	1,587	54,115	SH		SOLE		54,115	0	0
NIKE Inc	Common Stock	654106103	1,561	18,786	SH		SOLE		18,786	0	0
Gilead Sciences Inc	Common Stock	375558103	1,502	24,348	SH		SOLE		24,348	0	0
Regeneron Pharmaceuticals Inc	Common Stock	75886F107	1,470	2,134	SH		SOLE		2,134	0	0
Analog Devices Inc	Common Stock	032654105	1,459	10,473	SH		SOLE		10,473	0	0
Salesforce Inc	Common Stock	79466L302	1,454	10,109	SH		SOLE		10,109	0	0
Applied Materials Inc	Common Stock	038222105	1,421	17,348	SH		SOLE		17,348	0	0
Honeywell International Inc	Common Stock	438516106	1,364	8,170	SH		SOLE		8,170	0	0
Legend Biotech Corp	ADR	52490G102	1,347	33,009	SH		DFND		33,009	0	0
VanEck Gold Miners ETF/USA	ETP	92189F106	1,289	53,424	SH		SOLE		53,424	0	0
Netflix Inc	Common Stock	64110L106	1,255	5,332	SH		SOLE		5,332	0	0
Biogen Inc	Common Stock	09062X103	1,239	4,639	SH		SOLE		4,639	0	0
Fiserv Inc	Common Stock	337738108	1,214	12,977	SH		SOLE		12,977	0	0
Marriott International Inc/MD	Common Stock	571903202	1,196	8,535	SH		SOLE		8,535	0	0
Starbucks Corp	Common Stock	855244109	1,160	13,765	SH		SOLE		13,765	0	0
United States 12 Month Oil Fun	ETP	91288V103	1,137	35,000	SH		SOLE		35,000	0	0
Micron Technology Inc	Common Stock	595112103	1,124	22,429	SH		SOLE		22,429	0	0
International Business Machine	Common Stock	459200101	1,090	9,176	SH		SOLE		9,176	0	0
UnitedHealth Group Inc	Common Stock	91324P102	1,082	2,142	SH		SOLE		2,142	0	0
Moderna Inc	Common Stock	60770K107	1,057	8,940	SH		SOLE		8,940	0	0
AbbVie Inc	Common Stock	00287Y109	1,056	7,870	SH		SOLE		7,870	0	0
Lam Research Corp	Common Stock	512807108	1,020	2,786	SH		SOLE		2,786	0	0
Johnson & Johnson	Common Stock	478160104	998	6,110	SH		SOLE		6,110	0	0
Berkshire Hathaway Inc	Common Stock	084670702	976	3,655	SH		SOLE		3,655	0	0
ON Semiconductor Corp	Common Stock	682189105	947	15,194	SH		SOLE		15,194	0	0
Oracle Corp	Common Stock	68389X105	945	15,473	SH		SOLE		15,473	0	0
Synopsys Inc	Common Stock	871607107	939	3,074	SH		SOLE		3,074	0	0
Intuitive Surgical Inc	Common Stock	46120E602	918	4,898	SH		SOLE		4,898	0	0
Mondelez International Inc	Common Stock	609207105	911	16,610	SH		SOLE		16,610	0	0
Cadence Design Systems Inc	Common Stock	127387108	905	5,538	SH		SOLE		5,538	0	0
KLA Corp	Common Stock	482480100	891	2,945	SH		SOLE		2,945	0	0
Autodesk Inc	Common Stock	052769106	817	4,372	SH		SOLE		4,372	0	0
iShares iBoxx $ Investment Gra	ETP	464287242	809	7,900	SH		DFND		7,900	0	0
Booking Holdings Inc	Common Stock	09857L108	802	488	SH		SOLE		488	0	0
NXP Semiconductors NV	Common Stock	N6596X109	779	5,278	SH		SOLE		5,278	0	0
ServiceNow Inc	Common Stock	81762P102	775	2,052	SH		SOLE		2,052	0	0
Paychex Inc	Common Stock	704326107	769	6,851	SH		SOLE		6,851	0	0
Exxon Mobil Corp	Common Stock	30231G102	737	8,440	SH		SOLE		8,440	0	0
Fortinet Inc	Common Stock	34959E109	725	14,750	SH		SOLE		14,750	0	0
CSX Corp	Common Stock	126408103	696	26,122	SH		SOLE		26,122	0	0
Activision Blizzard Inc	Common Stock	00507V109	690	9,279	SH		SOLE		9,279	0	0
Microchip Technology Inc	Common Stock	595017104	681	11,152	SH		SOLE		11,152	0	0
Seagen Inc	Common Stock	81181C104	673	4,916	SH		SOLE		4,916	0	0
Eli Lilly & Co	Common Stock	532457108	649	2,007	SH		SOLE		2,007	0	0
JPMorgan Chase & Co	Common Stock	46625H100	621	5,939	SH		SOLE		5,939	0	0
Pfizer Inc	Common Stock	717081103	617	14,091	SH		SOLE		14,091	0	0
Procter & Gamble Co/The	Common Stock	742718109	611	4,839	SH		SOLE		4,839	0	0
Cognizant Technology Solutions	Common Stock	192446102	602	10,476	SH		SOLE		10,476	0	0
Incyte Corp	Common Stock	45337C102	584	8,770	SH		SOLE		8,770	0	0
Charter Communications Inc	Common Stock	16119P108	580	1,912	SH		SOLE		1,912	0	0
Home Depot Inc/The	Common Stock	437076102	574	2,081	SH		SOLE		2,081	0	0
Keurig Dr Pepper Inc	Common Stock	49271V100	571	15,939	SH		SOLE		15,939	0	0
Merck & Co Inc	Common Stock	58933Y105	570	6,623	SH		SOLE		6,623	0	0
O'Reilly Automotive Inc	Common Stock	67103H107	556	790	SH		SOLE		790	0	0
American Electric Power Co Inc	Common Stock	025537101	533	6,167	SH		SOLE		6,167	0	0
Monster Beverage Corp	Common Stock	61174X109	527	6,056	SH		SOLE		6,056	0	0
Chevron Corp	Common Stock	166764100	524	3,648	SH		SOLE		3,648	0	0
HUTCHMED China Ltd	ADR	44842L103	522	58,861	SH		DFND		58,861	0	0
Thermo Fisher Scientific Inc	Common Stock	883556102	518	1,022	SH		SOLE		1,022	0	0
Dexcom Inc	Common Stock	252131107	496	6,156	SH		SOLE		6,156	0	0
Palo Alto Networks Inc	Common Stock	697435105	490	2,994	SH		SOLE		2,994	0	0
Apellis Pharmaceuticals Inc	Common Stock	03753U106	482	7,050	SH		SOLE		7,050	0	0
Illumina Inc	Common Stock	452327109	481	2,521	SH		SOLE		2,521	0	0
Global Blood Therapeutics Inc	Common Stock	37890U108	479	7,030	SH		SOLE		7,030	0	0
SpringWorks Therapeutics Inc	Common Stock	85205L107	479	16,803	SH		SOLE		16,803	0	0
Biohaven Ltd	Common Stock	G1110E107	478	3,160	SH		SOLE		3,160	0	0
ChemoCentryx Inc	Common Stock	16383L106	478	9,252	SH		SOLE		9,252	0	0
Neurocrine Biosciences Inc	Common Stock	64125C109	475	4,473	SH		SOLE		4,473	0	0
CRISPR Therapeutics AG	Common Stock	H17182108	465	7,113	SH		SOLE		7,113	0	0
Cintas Corp	Common Stock	172908105	465	1,197	SH		SOLE		1,197	0	0
Fidelity National Information	Common Stock	31620M106	464	6,146	SH		SOLE		6,146	0	0
Kraft Heinz Co/The	Common Stock	500754106	463	13,883	SH		SOLE		13,883	0	0
IVERIC bio Inc	Common Stock	46583P102	460	25,624	SH		SOLE		25,624	0	0
Abbott Laboratories	Common Stock	002824100	459	4,748	SH		SOLE		4,748	0	0
Danaher Corp	Common Stock	235851102	458	1,774	SH		SOLE		1,774	0	0
Halozyme Therapeutics Inc	Common Stock	40637H109	455	11,505	SH		SOLE		11,505	0	0
Ionis Pharmaceuticals Inc	Common Stock	462222100	450	10,170	SH		SOLE		10,170	0	0
Ironwood Pharmaceuticals Inc	Common Stock	46333X108	449	43,304	SH		SOLE		43,304	0	0
ACADIA Pharmaceuticals Inc	Common Stock	004225108	448	27,407	SH		SOLE		27,407	0	0
BioCryst Pharmaceuticals Inc	Common Stock	09058V103	446	35,417	SH		SOLE		35,417	0	0
Horizon Therapeutics Plc	Common Stock	G46188101	446	7,207	SH		SOLE		7,207	0	0
PTC Therapeutics Inc	Common Stock	69366J200	446	8,881	SH		SOLE		8,881	0	0
United Therapeutics Corp	Common Stock	91307C102	446	2,131	SH		SOLE		2,131	0	0
Sarepta Therapeutics Inc	Common Stock	803607100	445	4,022	SH		SOLE		4,022	0	0
IDEXX Laboratories Inc	Common Stock	45168D104	444	1,364	SH		SOLE		1,364	0	0
Prothena Corp PLC	Common Stock	G72800108	444	7,329	SH		SOLE		7,329	0	0
Sage Therapeutics Inc	Common Stock	78667J108	444	11,341	SH		SOLE		11,341	0	0
Alkermes PLC	Common Stock	G01767105	443	19,839	SH		SOLE		19,839	0	0
Coca-Cola Co/The	Common Stock	191216100	442	7,882	SH		SOLE		7,882	0	0
Rhythm Pharmaceuticals Inc	Common Stock	76243J105	442	18,035	SH		SOLE		18,035	0	0
Exelon Corp	Common Stock	30161N101	441	11,772	SH		SOLE		11,772	0	0
Bristol-Myers Squibb Co	Common Stock	110122108	439	6,182	SH		SOLE		6,182	0	0
CTI BioPharma Corp	Common Stock	12648L601	437	75,133	SH		SOLE		75,133	0	0
Denali Therapeutics Inc	Common Stock	24823R105	437	14,254	SH		SOLE		14,254	0	0
BioMarin Pharmaceutical Inc	Common Stock	09061G101	435	5,126	SH		SOLE		5,126	0	0
Amicus Therapeutics Inc	Common Stock	03152W109	435	41,712	SH		SOLE		41,712	0	0
Karuna Therapeutics Inc	Common Stock	48576A100	431	1,914	SH		SOLE		1,914	0	0
Alnylam Pharmaceuticals Inc	Common Stock	02043Q107	427	2,134	SH		SOLE		2,134	0	0
Dynavax Technologies Corp	Common Stock	268158201	427	40,888	SH		SOLE		40,888	0	0
Bank of America Corp	Common Stock	060505104	424	14,027	SH		SOLE		14,027	0	0
Cytokinetics Inc	Common Stock	23282W605	423	8,738	SH		SOLE		8,738	0	0
Bluebird Bio Inc	Common Stock	09609G100	422	66,715	SH		SOLE		66,715	0	0
Verve Therapeutics Inc	Common Stock	92539P101	422	12,292	SH		SOLE		12,292	0	0
Xcel Energy Inc	Common Stock	98389B100	419	6,541	SH		SOLE		6,541	0	0
MercadoLibre Inc	Common Stock	58733R102	418	505	SH		SOLE		505	0	0
Exelixis Inc	Common Stock	30161Q104	417	26,611	SH		SOLE		26,611	0	0
Intellia Therapeutics Inc	Common Stock	45826J105	414	7,393	SH		SOLE		7,393	0	0
Blueprint Medicines Corp	Common Stock	09627Y109	413	6,262	SH		SOLE		6,262	0	0
Insmed Inc	Common Stock	457669307	413	19,185	SH		SOLE		19,185	0	0
Arcus Biosciences Inc	Common Stock	03969F109	411	15,720	SH		SOLE		15,720	0	0
I-Mab	ADR	44975P103	410	102,157	SH		SOLE		102,157	0	0
Vir Biotechnology Inc	Common Stock	92764N102	410	21,284	SH		SOLE		21,284	0	0
Arrowhead Pharmaceuticals Inc	Common Stock	04280A100	408	12,351	SH		SOLE		12,351	0	0
Iovance Biotherapeutics Inc	Common Stock	462260100	407	42,531	SH		SOLE		42,531	0	0
Airbnb Inc	Common Stock	009066101	402	3,831	SH		SOLE		3,831	0	0
Amphenol Corp	Common Stock	032095101	402	6,009	SH		SOLE		6,009	0	0
Celldex Therapeutics Inc	Common Stock	15117B202	401	14,278	SH		SOLE		14,278	0	0
Ultragenyx Pharmaceutical Inc	Common Stock	90400D108	401	9,673	SH		SOLE		9,673	0	0
Beam Therapeutics Inc	Common Stock	07373V105	395	8,283	SH		SOLE		8,283	0	0
Natera Inc	Common Stock	632307104	394	9,002	SH		SOLE		9,002	0	0
Veracyte Inc	Common Stock	92337F107	394	23,762	SH		SOLE		23,762	0	0
Mirati Therapeutics Inc	Common Stock	60468T105	393	5,620	SH		SOLE		5,620	0	0
Electronic Arts Inc	Common Stock	285512109	389	3,363	SH		SOLE		3,363	0	0
Prometheus Biosciences Inc	Common Stock	74349U108	385	6,532	SH		SOLE		6,532	0	0
Roper Technologies Inc	Common Stock	776696106	383	1,066	SH		SOLE		1,066	0	0
Exact Sciences Corp	Common Stock	30063P105	381	11,718	SH		SOLE		11,718	0	0
Twist Bioscience Corp	Common Stock	90184D100	381	10,817	SH		SOLE		10,817	0	0
Fate Therapeutics Inc	Common Stock	31189P102	380	16,952	SH		SOLE		16,952	0	0
ANSYS Inc	Common Stock	03662Q105	378	1,703	SH		SOLE		1,703	0	0
Enphase Energy Inc	Common Stock	29355A107	377	1,359	SH		SOLE		1,359	0	0
Motorola Solutions Inc	Common Stock	620076307	377	1,682	SH		SOLE		1,682	0	0
CVS Health Corp	Common Stock	126650100	375	3,934	SH		SOLE		3,934	0	0
Walmart Inc	Common Stock	931142103	374	2,886	SH		SOLE		2,886	0	0
Editas Medicine Inc	Common Stock	28106W103	368	30,092	SH		SOLE		30,092	0	0
Dollar Tree Inc	Common Stock	256746108	367	2,698	SH		SOLE		2,698	0	0
Marvell Technology Inc	Common Stock	573874104	366	8,519	SH		SOLE		8,519	0	0
REVOLUTION Medicines Inc	Common Stock	76155X100	363	18,417	SH		SOLE		18,417	0	0
Ross Stores Inc	Common Stock	778296103	358	4,252	SH		SOLE		4,252	0	0
Catalyst Pharmaceuticals Inc	Common Stock	14888U101	357	27,825	SH		SOLE		27,825	0	0
TE Connectivity Ltd	Common Stock	H84989104	357	3,239	SH		SOLE		3,239	0	0
Crowdstrike Holdings Inc	Common Stock	22788C105	352	2,138	SH		SOLE		2,138	0	0
PACCAR Inc	Common Stock	693718108	352	4,210	SH		SOLE		4,210	0	0
Travere Therapeutics Inc	Common Stock	89422G107	349	14,145	SH		SOLE		14,145	0	0
Walt Disney Co/The	Common Stock	254687106	348	3,692	SH		SOLE		3,692	0	0
VeriSign Inc	Common Stock	92343E102	348	2,004	SH		SOLE		2,004	0	0
Royal Caribbean Cruises Ltd	Common Stock	V7780T103	346	9,137	SH		SOLE		9,137	0	0
McDonald's Corp	Common Stock	580135101	344	1,490	SH		SOLE		1,490	0	0
CareDx Inc	Common Stock	14167L103	342	20,073	SH		SOLE		20,073	0	0
Allogene Therapeutics Inc	Common Stock	019770106	341	31,608	SH		SOLE		31,608	0	0
Emergent BioSolutions Inc	Common Stock	29089Q105	339	16,148	SH		SOLE		16,148	0	0
Elevance Health Inc	Common Stock	036752103	337	741	SH		SOLE		741	0	0
Medtronic PLC	Common Stock	G5960L103	332	4,108	SH		SOLE		4,108	0	0
Bridgebio Pharma Inc	Common Stock	10806X102	331	33,350	SH		SOLE		33,350	0	0
Old Dominion Freight Line Inc	Common Stock	679580100	331	1,329	SH		SOLE		1,329	0	0
JD.com Inc	ADR	47215P106	327	6,503	SH		DFND		6,503	0	0
Verisk Analytics Inc	Common Stock	92345Y106	326	1,913	SH		SOLE		1,913	0	0
Carnival Corp	Common Stock	143658300	324	46,116	SH		SOLE		46,116	0	0
Verizon Communications Inc	Common Stock	92343V104	323	8,505	SH		SOLE		8,505	0	0
Fastenal Co	Common Stock	311900104	321	6,970	SH		SOLE		6,970	0	0
AstraZeneca PLC	ADR	046353108	318	5,792	SH		SOLE		5,792	0	0
Walgreens Boots Alliance Inc	Common Stock	931427108	317	10,081	SH		SOLE		10,081	0	0
Sorrento Therapeutics Inc	Common Stock	83587F202	316	200,990	SH		SOLE		200,990	0	0
TG Therapeutics Inc	Common Stock	88322Q108	315	53,150	SH		SOLE		53,150	0	0
Constellation Energy Corp	Common Stock	21037T109	313	3,765	SH		SOLE		3,765	0	0
NextEra Energy Inc	Common Stock	65339F101	312	3,979	SH		SOLE		3,979	0	0
ImmunoGen Inc	Common Stock	45253H101	311	65,128	SH		SOLE		65,128	0	0
MannKind Corp	Common Stock	56400P706	309	100,058	SH		SOLE		100,058	0	0
Wells Fargo & Co	Common Stock	949746101	309	7,681	SH		SOLE		7,681	0	0
Workday Inc	Common Stock	98138H101	307	2,015	SH		SOLE		2,015	0	0
Global Payments Inc	Common Stock	37940X102	306	2,831	SH		SOLE		2,831	0	0
Atlassian Corp	Common Stock	049468101	305	1,447	SH		SOLE		1,447	0	0
Relay Therapeutics Inc	Common Stock	75943R102	302	13,483	SH		SOLE		13,483	0	0
Copart Inc	Common Stock	217204106	301	2,830	SH		SOLE		2,830	0	0
Cigna Corp	Common Stock	125523100	298	1,073	SH		SOLE		1,073	0	0
Madrigal Pharmaceuticals Inc	Common Stock	558868105	295	4,538	SH		SOLE		4,538	0	0
Cerevel Therapeutics Holdings	Common Stock	15678U128	294	10,400	SH		SOLE		10,400	0	0
Align Technology Inc	Common Stock	016255101	289	1,397	SH		SOLE		1,397	0	0
Keysight Technologies Inc	Common Stock	49338L103	288	1,830	SH		SOLE		1,830	0	0
Arista Networks Inc	Common Stock	040413106	283	2,504	SH		SOLE		2,504	0	0
Zentalis Pharmaceuticals Inc	Common Stock	98943L107	274	12,628	SH		SOLE		12,628	0	0
Scorpio Tankers Inc	Common Stock	Y7542C130	274	6,508	SH		DFND		6,508	0	0
Novavax Inc	Common Stock	670002401	273	15,017	SH		SOLE		15,017	0	0
uniQure NV	Common Stock	N90064101	271	14,470	SH		SOLE		14,470	0	0
Kymera Therapeutics Inc	Common Stock	501575104	269	12,342	SH		SOLE		12,342	0	0
Linde PLC	Common Stock	G5494J103	269	996	SH		SOLE		996	0	0
Skyworks Solutions Inc	Common Stock	83088M102	269	3,149	SH		SOLE		3,149	0	0
Kura Oncology Inc	Common Stock	50127T109	265	19,380	SH		SOLE		19,380	0	0
Agios Pharmaceuticals Inc	Common Stock	00847X104	264	9,340	SH		SOLE		9,340	0	0
Altimmune Inc	Common Stock	02155H200	264	20,640	SH		SOLE		20,640	0	0
ConocoPhillips	Common Stock	20825C104	262	2,559	SH		SOLE		2,559	0	0
Philip Morris International In	Common Stock	718172109	261	3,139	SH		SOLE		3,139	0	0
Deciphera Pharmaceuticals Inc	Common Stock	24344T101	257	13,887	SH		SOLE		13,887	0	0
Zoetis Inc	Common Stock	98978V103	256	1,725	SH		SOLE		1,725	0	0
Baidu Inc	ADR	056752108	254	2,166	SH		SOLE		2,166	0	0
Datadog Inc	Common Stock	23804L103	254	2,866	SH		SOLE		2,866	0	0
Humana Inc	Common Stock	444859102	254	523	SH		SOLE		523	0	0
Karyopharm Therapeutics Inc	Common Stock	48576U106	251	45,924	SH		SOLE		45,924	0	0
Krystal Biotech Inc	Common Stock	501147102	250	3,591	SH		SOLE		3,591	0	0
Stryker Corp	Common Stock	863667101	250	1,232	SH		SOLE		1,232	0	0
Rocket Pharmaceuticals Inc	Common Stock	77313F106	249	15,578	SH		SOLE		15,578	0	0
Lowe's Cos Inc	Common Stock	548661107	246	1,308	SH		SOLE		1,308	0	0
Syndax Pharmaceuticals Inc	Common Stock	87164F105	242	10,064	SH		SOLE		10,064	0	0
Union Pacific Corp	Common Stock	907818108	242	1,243	SH		SOLE		1,243	0	0
Raytheon Technologies Corp	Common Stock	75513E101	241	2,943	SH		SOLE		2,943	0	0
United Parcel Service Inc	Common Stock	911312106	239	1,482	SH		SOLE		1,482	0	0
eBay Inc	Common Stock	278642103	238	6,459	SH		SOLE		6,459	0	0
Becton Dickinson and Co	Common Stock	075887109	237	1,062	SH		SOLE		1,062	0	0
Ocugen Inc	Common Stock	67577C105	237	132,938	SH		SOLE		132,938	0	0
PMV Pharmaceuticals Inc	Common Stock	69353Y103	237	19,884	SH		SOLE		19,884	0	0
Lucid Group Inc	Common Stock	549498103	236	16,889	SH		SOLE		16,889	0	0
HP Inc	Common Stock	40434L105	230	9,248	SH		SOLE		9,248	0	0
Avid Bioservices Inc	Common Stock	05368M106	229	11,979	SH		SOLE		11,979	0	0
Arcutis Biotherapeutics Inc	Common Stock	03969K108	228	11,947	SH		SOLE		11,947	0	0
Boston Scientific Corp	Common Stock	101137107	228	5,875	SH		SOLE		5,875	0	0
Enanta Pharmaceuticals Inc	Common Stock	29251M106	227	4,381	SH		SOLE		4,381	0	0
Gartner Inc	Common Stock	366651107	225	812	SH		SOLE		812	0	0
Myriad Genetics Inc	Common Stock	62855J104	225	11,783	SH		SOLE		11,783	0	0
Vericel Corp	Common Stock	92346J108	225	9,701	SH		SOLE		9,701	0	0
Corning Inc	Common Stock	219350105	222	7,638	SH		SOLE		7,638	0	0
Charles Schwab Corp/The	Common Stock	808513105	222	3,092	SH		SOLE		3,092	0	0
Zscaler Inc	Common Stock	98980G102	221	1,347	SH		SOLE		1,347	0	0
Inovio Pharmaceuticals Inc	Common Stock	45773H201	220	127,683	SH		SOLE		127,683	0	0
McKesson Corp	Common Stock	58155Q103	219	645	SH		SOLE		645	0	0
Morgan Stanley	Common Stock	617446448	219	2,769	SH		SOLE		2,769	0	0
AT&T Inc	Common Stock	00206R102	217	14,163	SH		SOLE		14,163	0	0
Intercept Pharmaceuticals Inc	Common Stock	45845P108	216	15,508	SH		SOLE		15,508	0	0
Ligand Pharmaceuticals Inc	Common Stock	53220K504	216	2,503	SH		SOLE		2,503	0	0
Cogent Biosciences Inc	Common Stock	19240Q201	215	14,390	SH		SOLE		14,390	0	0
Sirius XM Holdings Inc	Common Stock	82968B103	215	37,608	SH		SOLE		37,608	0	0
Edwards Lifesciences Corp	Common Stock	28176E108	213	2,575	SH		SOLE		2,575	0	0
REGENXBIO Inc	Common Stock	75901B107	213	8,055	SH		SOLE		8,055	0	0
CDW Corp/DE	Common Stock	12514G108	212	1,357	SH		SOLE		1,357	0	0
S&P Global Inc	Common Stock	78409V104	210	687	SH		SOLE		687	0	0
EPAM Systems Inc	Common Stock	29414B104	208	573	SH		SOLE		573	0	0
FibroGen Inc	Common Stock	31572Q808	204	15,662	SH		SOLE		15,662	0	0
Xencor Inc	Common Stock	98401F105	204	7,855	SH		SOLE		7,855	0	0
American Tower Corp	REIT	03027X100	202	942	SH		SOLE		942	0	0
Centene Corp	Common Stock	15135B101	201	2,578	SH		SOLE		2,578	0	0
Protagonist Therapeutics Inc	Common Stock	74366E102	201	23,848	SH		SOLE		23,848	0	0
Myovant Sciences Ltd	Common Stock	G637AM102	200	11,153	SH		SOLE		11,153	0	0
EQRx Inc	Common Stock	26886C107	199	40,228	SH		SOLE		40,228	0	0
Agenus Inc	Common Stock	00847G705	197	95,871	SH		SOLE		95,871	0	0
Anavex Life Sciences Corp	Common Stock	032797300	194	18,815	SH		SOLE		18,815	0	0
Gossamer Bio Inc	Common Stock	38341P102	189	15,769	SH		SOLE		15,769	0	0
Arcturus Therapeutics Holdings	Common Stock	03969T109	188	12,713	SH		SOLE		12,713	0	0
Coherus Biosciences Inc	Common Stock	19249H103	178	18,473	SH		SOLE		18,473	0	0
Sana Biotechnology Inc	Common Stock	799566104	177	29,495	SH		SOLE		29,495	0	0
Heron Therapeutics Inc	Common Stock	427746102	175	41,391	SH		SOLE		41,391	0	0
Vaxart Inc	Common Stock	92243A200	158	72,516	SH		SOLE		72,516	0	0
Hewlett Packard Enterprise Co	Common Stock	42824C109	156	13,052	SH		SOLE		13,052	0	0
Nkarta Inc	Common Stock	65487U108	146	11,085	SH		SOLE		11,085	0	0
Kezar Life Sciences Inc	Common Stock	49372L100	145	16,821	SH		SOLE		16,821	0	0
Atara Biotherapeutics Inc	Common Stock	046513107	139	36,673	SH		SOLE		36,673	0	0
ImmunityBio Inc	Common Stock	45256X103	138	27,804	SH		SOLE		27,804	0	0
Sangamo Therapeutics Inc	Common Stock	800677106	136	27,723	SH		SOLE		27,723	0	0
Viatris Inc	Common Stock	92556V106	133	15,557	SH		SOLE		15,557	0	0
Recursion Pharmaceuticals Inc	Common Stock	75629V104	126	11,859	SH		SOLE		11,859	0	0
Alector Inc	Common Stock	014442107	122	12,866	SH		SOLE		12,866	0	0
Norwegian Cruise Line Holdings	Common Stock	G66721104	120	10,598	SH		SOLE		10,598	0	0
Lyell Immunopharma Inc	Common Stock	55083R104	104	14,191	SH		SOLE		14,191	0	0
Mersana Therapeutics Inc	Common Stock	59045L106	99	14,695	SH		SOLE		14,695	0	0
ADMA Biologics Inc	Common Stock	000899104	97	39,858	SH		SOLE		39,858	0	0
Seres Therapeutics Inc	Common Stock	81750R102	90	14,070	SH		SOLE		14,070	0	0
Geron Corp	Common Stock	374163103	89	37,938	SH		SOLE		37,938	0	0
Point Biopharma Global Inc	Common Stock	730541109	79	10,212	SH		SOLE		10,212	0	0
MiMedx Group Inc	Common Stock	602496101	32	11,207	SH		SOLE		11,207	0	0
Alaunos Therapeutics Inc	Common Stock	98973P101	26	15,167	SH		SOLE		15,167	0	0
Adagene Inc	ADR	005329107	13	10,310	SH		SOLE		10,310	0	0