DISCLAIMER This presentation (“Presentation”) is for informational purposes only to assist interested parties in making their own evaluation of Carmell Therapeutics (the “Company”). The information contained herein does not purport to be all-inclusive and of the Company nor any of their respective affiliates nor any of its or their control persons, officers, directors, employees or representatives makes any representation or warranty, express or implied, as to the accuracy, completeness or reliability of the information contained in this Presentation. You should consult your own counsel and tax and financial advisors as to legal and related matters concerning the matters described herein, and, by accepting this Presentation, you confirm that you are not relying upon the information contained herein tomakeanydecision. Thereadershallnot relyupon anystatement, representation orwarranty madebyanyotherperson,firm orcorporation in makingits investment ordecisionto investin theCompany.TheCompanynor any of their respective affiliates nor any of its or their control persons, officers, directors, employees or representatives, shall be liable to the reader for any information set forth herein or any action taken or not taken by any reader, including any investment in shares of the Company. Certain information contained in this Presentation relates to oris based on studies, publications, surveys and the Company’s own internal estimates and research. In addition, allof the market data included in this Presentation involves a number of assumptions and limitations, and therecan be no guarantee as to theaccuracyorreliability of suchassumptions. Finally, while theCompany believes its internal research is reliable, such research hasnot been verified byanyindependent source. No Offer or Solicitation. This communication is for informational purposes only and does not constitute, or form a part of, an offer to sell or the solicitation of an offer to sell or an offer to buy or the solicitation ofan offerto buyanysecurities,and thereshallbenosaleofsecurities, in anyjurisdiction in whichsuchoffer,solicitationorsalewould beunlawfulpriortoregistrationorqualification under thesecurities laws of any such jurisdiction. No offer of securities shallbemadeexcept by means of a prospectus meetingthe requirements of Section 10 of theSecurities Act of 1933, as amended, and otherwise in accordancewith applicable law. Forward-Looking Statements. Certain statements in this Presentation may be considered forward-looking statements. Forward-looking statements generally relate to future events or the Company’s future financial or operating performance. For example, statements concerning the following include forward-looking statements: the success, cost and timing of product development activities, includingtimingof initiation, completion and data readouts forclinicaltrials; thepotentialattributesand benefits of product candidates, includingin comparisonto otherproducts on the market forthe same or similar indications; ability to compete with other companies currently marketing or engaged in the development of treatments for relevant indications; the size and growth potential of the marketsforproductcandidatesand abilityto servethosemarkets;therate anddegreeof marketacceptanceofproduct candidates,if approved;thepotentialpricingof productcandidates, ifapproved; the proceeds of the Business Combination and the Company’s expected cash runway; and the potential effects of the Business Combination on the Company. In some cases, you can identify forward-looking statements by terminology such as “may”, “should”, “expect”, “intend”, “will”, “estimate”, “anticipate”, “believe”, “predict”, “potential” or “continue”, or the negatives of these terms or variationsofthem orsimilarterminology.Suchforward-lookingstatements aresubjectto risks,uncertainties,and otherfactors whichcould causeactualresults todiffermateriallyfromthoseexpressed orimplied bysuch forward looking statements. These forward-looking statements are based upon estimates and assumptions that, while considered reasonable by the Company and its management, as the case may be, are inherently uncertain. New risksand uncertainties may emergefrom timeto time,and it is notpossibleto predictallrisksand uncertainties. Factors that maycauseactualresultsto differmateriallyfromcurrent expectations include, but are not limited to, various factors beyond management’s control including general economic conditions and other risks, uncertainties and factors set forth in the section entitled “Risk Factors” in ALPA’s final proxy, dated June 23, 2023, and other filings with the Securities and Exchange Commission (SEC), as well as factors associated with companies, such as the Company, that are engaged in clinical trials in the biopharma industry, including uncertainty in the timing or results of clinical trials and receipt of regulatory approvals for product candidates, and in the healthcare industry, includingtheimpact oftheCOVID-19pandemic; competition inthehealthcareindustry;inability to recruit orretaina sufficient numberof patients orphysicians and otheremployees;changes to federal and state healthcare laws and regulations; changes to reimbursement rates; overall business and economic conditions affecting the healthcare industry, including conditions pertaining to health plans andpayors;failure todevelop new technology and products, if approved; andsecurity breaches, loss of dataorother disruptions. Nothingin this Presentation should be regarded as a representation by any person that the forward-lookingstatements set forth herein willbeachieved orthat any of the contemplated results of such forward-lookingstatements willbeachieved. Youshould not placeunduerelianceonforward- lookingstatementsinthis Presentation, which speakonly asofthedatetheyaremadeand arequalifiedin their entirety by reference to the cautionary statements herein. Except as required by law, the Company does not undertake any duty to update these forward-looking statements. This Presentation contains certain financial forecast information of the Company. Such financialforecast information constitutes forward-looking information and is for illustrativepurposes only and should not be relied upon as necessarily being indicative of future results. The assumptions and estimates underlying such financial forecast information are inherently uncertain and are subject to a wide variety of significant business, economic, competitive and other risks and uncertainties. See “Forward-Looking Statements” above. Actual results may differ materially from the results contemplated by the financial forecast information contained in this Presentation, and the inclusion of such information in this Presentation should not be regarded as a representation by any person that the results reflected in such forecasts willbe achieved. 4
