GV 2019 SC 13G Adagio Therapeutics / GV 2019 ownership change

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

Schedule 13G

Under the Securities Exchange Act of 1934

(Amendment No. )*

Adagio Therapeutics, Inc.

(Name of Issuer)

Common Stock, par value $0.0001 per share

(Title of Class of Securities)

00534A102

(CUSIP Number)

December 31, 2021

(Date of Event Which Requires Filing of this Statement)

Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

☐ Rule 13d-1(b)

☐ Rule 13d-1(c)

☒ Rule 13d-1(d)

* The remainder of this cover page shall be filled out for a reporting person’s initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter the disclosures provided in a prior cover page.

The information required in the remainder of this cover page shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of 1934 (“Act”) or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).

(Continued on following pages)

CUSIP No. 00534A102 13G

1	NAME OF REPORTING PERSONS   GV 2019, L.P.
2	CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP   (a)  ☐        (b)  ☒
3	SEC USE ONLY
4	CITIZENSHIP OR PLACE OF ORGANIZATION   Delaware

NUMBER OF SHARES  BENEFICIALLY  OWNED BY EACH REPORTING PERSON WITH:	5	SOLE VOTING POWER   5,200,545 (1)
	6	SHARED VOTING POWER   See response to row 5.
	7	SOLE DISPOSITIVE POWER   5,200,545 (2)
	8	SHARED DISPOSITIVE POWER   See response to row 7.

9	AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON   5,200,545
10	CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES   ☐
11	PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9   4.67% (3)
12	TYPE OF REPORTING PERSON   PN

⁽¹⁾ Consists of 5,200,545 shares of the Issuer’s Common Stock held directly by GV 2019, L.P. GV 2019 GP, L.P. (the general partner of GV 2019, L.P.), GV 2019 GP, L.L.C. (the general partner of GV 2019 GP, L.P.), Alphabet Holdings LLC (the sole member of GV 2019 GP, L.L.C.), XXVI Holdings Inc. (the sole member of Alphabet Holdings LLC), and Alphabet Inc. (the controlling stockholder of XXVI Holdings Inc.) may each be deemed to have sole power to vote the shares held directly by GV 2019, L.P.

⁽²⁾ Consists of 5,200,545 shares of the Issuer’s Common Stock held directly by GV 2019, L.P. GV 2019 GP, L.P. (the general partner of GV 2019, L.P.), GV 2019 GP, L.L.C. (the general partner of GV 2019 GP, L.P.), Alphabet Holdings LLC (the sole member of GV 2019 GP, L.L.C.), XXVI Holdings Inc. (the sole member of Alphabet Holdings LLC), and Alphabet Inc. (the controlling stockholder of XXVI Holdings Inc.) may each be deemed to have sole power to dispose of the shares held directly by GV 2019, L.P.

⁽³⁾ Based on 111,251,660 shares of the Issuer’s Common Stock outstanding as of November 8, 2021 as disclosed in the Issuer’s Form 10-Q filed with the Securities and Exchange Commission on November 15, 2021.

Page 2 of 16

CUSIP No. 00534A102 13G

1	NAME OF REPORTING PERSONS   GV 2019 GP, L.P.
2	CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP   (a)  ☐        (b)  ☒
3	SEC USE ONLY
4	CITIZENSHIP OR PLACE OF ORGANIZATION   Delaware

NUMBER OF SHARES  BENEFICIALLY  OWNED BY EACH REPORTING PERSON WITH:	5	SOLE VOTING POWER   5,200,545 (1)
	6	SHARED VOTING POWER   See response to row 5.
	7	SOLE DISPOSITIVE POWER   5,200,545 (2)
	8	SHARED DISPOSITIVE POWER   See response to row 7.

9	AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON   5,200,545
10	CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES   ☐
11	PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9   4.67% (3)
12	TYPE OF REPORTING PERSON   PN

⁽¹⁾ Consists of 5,200,545 shares of the Issuer’s Common Stock held directly by GV 2019, L.P. GV 2019 GP, L.P. (the general partner of GV 2019, L.P.), GV 2019 GP, L.L.C. (the general partner of GV 2019 GP, L.P.), Alphabet Holdings LLC (the sole member of GV 2019 GP, L.L.C.), XXVI Holdings Inc. (the sole member of Alphabet Holdings LLC), and Alphabet Inc. (the controlling stockholder of XXVI Holdings Inc.) may each be deemed to have sole power to vote the shares held directly by GV 2019, L.P.

⁽²⁾ Consists of 5,200,545 shares of the Issuer’s Common Stock held directly by GV 2019, L.P. GV 2019 GP, L.P. (the general partner of GV 2019, L.P.), GV 2019 GP, L.L.C. (the general partner of GV 2019 GP, L.P.), Alphabet Holdings LLC (the sole member of GV 2019 GP, L.L.C.), XXVI Holdings Inc. (the sole member of Alphabet Holdings LLC), and Alphabet Inc. (the controlling stockholder of XXVI Holdings Inc.) may each be deemed to have sole power to dispose of the shares held directly by GV 2019, L.P.

⁽³⁾ Based on 111,251,660 shares of the Issuer’s Common Stock outstanding as of November 8, 2021 as disclosed in the Issuer’s Form 10-Q filed with the Securities and Exchange Commission on November 15, 2021.

Page 3 of 16

CUSIP No. 00534A102 13G

1	NAME OF REPORTING PERSONS   GV 2019 GP, L.L.C.
2	CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP   (a)  ☐        (b)  ☒
3	SEC USE ONLY
4	CITIZENSHIP OR PLACE OF ORGANIZATION   Delaware

NUMBER OF SHARES  BENEFICIALLY  OWNED BY EACH REPORTING PERSON WITH:	5	SOLE VOTING POWER   5,200,545 (1)
	6	SHARED VOTING POWER   See response to row 5.
	7	SOLE DISPOSITIVE POWER.   5,200,545 (2)
	8	SHARED DISPOSITIVE POWER   See response to row 7.

9	AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON   5,200,545
10	CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES   ☐
11	PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9   4.67% (3)
12	TYPE OF REPORTING PERSON   OO

⁽¹⁾ Consists of 5,200,545 shares of the Issuer’s Common Stock held directly by GV 2019, L.P. GV 2019 GP, L.P. (the general partner of GV 2019, L.P.), GV 2019 GP, L.L.C. (the general partner of GV 2019 GP, L.P.), Alphabet Holdings LLC (the sole member of GV 2019 GP, L.L.C.), XXVI Holdings Inc. (the sole member of Alphabet Holdings LLC), and Alphabet Inc. (the controlling stockholder of XXVI Holdings Inc.) may each be deemed to have sole power to vote the shares held directly by GV 2019, L.P.

⁽²⁾ Consists of 5,200,545 shares of the Issuer’s Common Stock held directly by GV 2019, L.P. GV 2019 GP, L.P. (the general partner of GV 2019, L.P.), GV 2019 GP, L.L.C. (the general partner of GV 2019 GP, L.P.), Alphabet Holdings LLC (the sole member of GV 2019 GP, L.L.C.), XXVI Holdings Inc. (the sole member of Alphabet Holdings LLC), and Alphabet Inc. (the controlling stockholder of XXVI Holdings Inc.) may each be deemed to have sole power to dispose of the shares held directly by GV 2019, L.P.

⁽³⁾ Based on 111,251,660 shares of the Issuer’s Common Stock outstanding as of November 8, 2021 as disclosed in the Issuer’s Form 10-Q filed with the Securities and Exchange Commission on November 15, 2021.

Page 4 of 16

CUSIP No. 00534A102 13G

1	NAME OF REPORTING PERSONS   GV 2021, L.P.
2	CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP   (a)  ☐        (b)  ☒
3	SEC USE ONLY
4	CITIZENSHIP OR PLACE OF ORGANIZATION   Delaware

NUMBER OF SHARES  BENEFICIALLY  OWNED BY EACH REPORTING PERSON WITH:	5	SOLE VOTING POWER   480,240 (4)
	6	SHARED VOTING POWER   See response to row 5.
	7	SOLE DISPOSITIVE POWER   480,240 (5)
	8	SHARED DISPOSITIVE POWER   See response to row 7.

9	AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON   480,240
10	CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES   ☐
11	PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9   0.43% (3)
12	TYPE OF REPORTING PERSON   PN

⁽⁴⁾ Consists of 480,240 shares of the Issuer’s Common Stock held directly by GV 2021, L.P. GV 2021 GP, L.P. (the general partner of GV 2021, L.P.), GV 2021 GP, L.L.C. (the general partner of GV 2021 GP, L.P.), Alphabet Holdings LLC (the sole member of GV 2021 GP, L.L.C.), XXVI Holdings Inc. (the sole member of Alphabet Holdings LLC), and Alphabet Inc. (the controlling stockholder of XXVI Holdings Inc.) may each be deemed to have sole power to vote the shares held directly by GV 2021, L.P.

⁽⁵⁾ Consists of 480,240 shares of the Issuer’s Common Stock held directly by GV 2021, L.P. GV 2021 GP, L.P. (the general partner of GV 2021, L.P.), GV 2021 GP, L.L.C. (the general partner of GV 2021 GP, L.P.), Alphabet Holdings LLC (the sole member of GV 2021 GP, L.L.C.), XXVI Holdings Inc. (the sole member of Alphabet Holdings LLC), and Alphabet Inc. (the controlling stockholder of XXVI Holdings Inc.) may each be deemed to have sole power to dispose of the shares held directly by GV 2021, L.P.

⁽³⁾ Based on 111,251,660 shares of the Issuer’s Common Stock outstanding as of November 8, 2021 as disclosed in the Issuer’s Form 10-Q filed with the Securities and Exchange Commission on November 15, 2021.

Page 5 of 16

CUSIP No. 00534A102 13G

1	NAME OF REPORTING PERSONS   GV 2021 GP, L.P.
2	CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP   (a)  ☐        (b)  ☒
3	SEC USE ONLY
4	CITIZENSHIP OR PLACE OF ORGANIZATION   Delaware

NUMBER OF SHARES  BENEFICIALLY  OWNED BY EACH REPORTING PERSON WITH:	5	SOLE VOTING POWER   480,240 (4)
	6	SHARED VOTING POWER   See response to row 5.
	7	SOLE DISPOSITIVE POWER   480,240 (5)
	8	SHARED DISPOSITIVE POWER   See response to row 7.

9	AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON   480,240
10	CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES   ☐
11	PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9   0.43% (3)
12	TYPE OF REPORTING PERSON   PN

⁽⁴⁾ Consists of 480,240 shares of the Issuer’s Common Stock held directly by GV 2021, L.P. GV 2021 GP, L.P. (the general partner of GV 2021, L.P.), GV 2021 GP, L.L.C. (the general partner of GV 2021 GP, L.P.), Alphabet Holdings LLC (the sole member of GV 2021 GP, L.L.C.), XXVI Holdings Inc. (the sole member of Alphabet Holdings LLC), and Alphabet Inc. (the controlling stockholder of XXVI Holdings Inc.) may each be deemed to have sole power to vote the shares held directly by GV 2021, L.P.

⁽⁵⁾ Consists of 480,240 shares of the Issuer’s Common Stock held directly by GV 2021, L.P. GV 2021 GP, L.P. (the general partner of GV 2021, L.P.), GV 2021 GP, L.L.C. (the general partner of GV 2021 GP, L.P.), Alphabet Holdings LLC (the sole member of GV 2021 GP, L.L.C.), XXVI Holdings Inc. (the sole member of Alphabet Holdings LLC), and Alphabet Inc. (the controlling stockholder of XXVI Holdings Inc.) may each be deemed to have sole power to dispose of the shares held directly by GV 2021, L.P.

⁽³⁾ Based on 111,251,660 shares of the Issuer’s Common Stock outstanding as of November 8, 2021 as disclosed in the Issuer’s Form 10-Q filed with the Securities and Exchange Commission on November 15, 2021.

Page 6 of 16

CUSIP No. 00534A102 13G

1	NAME OF REPORTING PERSONS   GV 2021 GP, L.L.C.
2	CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP   (a)  ☐        (b)  ☒
3	SEC USE ONLY
4	CITIZENSHIP OR PLACE OF ORGANIZATION   Delaware

NUMBER OF SHARES  BENEFICIALLY  OWNED BY EACH REPORTING PERSON WITH:	5	SOLE VOTING POWER   480,240 (4)
	6	SHARED VOTING POWER   See response to row 5.
	7	SOLE DISPOSITIVE POWER.   480,240 (5)
	8	SHARED DISPOSITIVE POWER   See response to row 7.

9	AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON   480,240
10	CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES   ☐
11	PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9   0.43% (3)
12	TYPE OF REPORTING PERSON   OO

⁽⁴⁾ Consists of 480,240 shares of the Issuer’s Common Stock held directly by GV 2021, L.P. GV 2021 GP, L.P. (the general partner of GV 2021, L.P.), GV 2021 GP, L.L.C. (the general partner of GV 2021 GP, L.P.), Alphabet Holdings LLC (the sole member of GV 2021 GP, L.L.C.), XXVI Holdings Inc. (the sole member of Alphabet Holdings LLC), and Alphabet Inc. (the controlling stockholder of XXVI Holdings Inc.) may each be deemed to have sole power to vote the shares held directly by GV 2021, L.P.

⁽⁵⁾ Consists of 480,240 shares of the Issuer’s Common Stock held directly by GV 2021, L.P. GV 2021 GP, L.P. (the general partner of GV 2021, L.P.), GV 2021 GP, L.L.C. (the general partner of GV 2021 GP, L.P.), Alphabet Holdings LLC (the sole member of GV 2021 GP, L.L.C.), XXVI Holdings Inc. (the sole member of Alphabet Holdings LLC), and Alphabet Inc. (the controlling stockholder of XXVI Holdings Inc.) may each be deemed to have sole power to dispose of the shares held directly by GV 2021, L.P.

⁽³⁾ Based on 111,251,660 shares of the Issuer’s Common Stock outstanding as of November 8, 2021 as disclosed in the Issuer’s Form 10-Q filed with the Securities and Exchange Commission on November 15, 2021.

Page 7 of 16

CUSIP No. 00534A102 13G

1	NAME OF REPORTING PERSONS   Alphabet Holdings LLC
2	CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP   (a)  ☐        (b)  ☒
3	SEC USE ONLY
4	CITIZENSHIP OR PLACE OF ORGANIZATION   Delaware

NUMBER OF SHARES  BENEFICIALLY  OWNED BY EACH REPORTING PERSON WITH:	5	SOLE VOTING POWER   5,680,785 (6)
	6	SHARED VOTING POWER   See response to row 5.
	7	SOLE DISPOSITIVE POWER.   5,680,785 (7)
	8	SHARED DISPOSITIVE POWER   See response to row 7.

9	AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON   5,680,785
10	CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES   ☐
11	PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9   5.11% (3)
12	TYPE OF REPORTING PERSON   OO

⁽⁶⁾ Consists of 5,200,545 shares of the Issuer’s Common Stock held directly by GV 2019, L.P. and 480,240 shares of the Issuer’s Common Stock held directly by GV 2021, L.P. GV 2019 GP, L.P. (the general partner of GV 2019, L.P.), GV 2019 GP, L.L.C. (the general partner of GV 2019 GP, L.P.), Alphabet Holdings LLC (the sole member of GV 2019 GP, L.L.C.), XXVI Holdings Inc. (the sole member of Alphabet Holdings LLC), and Alphabet Inc. (the controlling stockholder of XXVI Holdings Inc.) may each be deemed to have sole power to vote the shares held directly by GV 2019, L.P. GV 2021 GP, L.P. (the general partner of GV 2021, L.P.), GV 2021 GP, L.L.C. (the general partner of GV 2021 GP, L.P.), Alphabet Holdings LLC (the sole member of GV 2021 GP, L.L.C.), XXVI Holdings Inc. (the sole member of Alphabet Holdings LLC), and Alphabet Inc. (the controlling stockholder of XXVI Holdings Inc.) may each be deemed to have sole power to vote the shares held directly by GV 2021, L.P.

⁽⁷⁾ Consists of 5,200,545 shares of the Issuer’s Common Stock held directly by GV 2019, L.P. and 480,240 shares of the Issuer’s Common Stock held directly by GV 2021, L.P. GV 2019 GP, L.P. (the general partner of GV 2019, L.P.), GV 2019 GP, L.L.C. (the general partner of GV 2019 GP, L.P.), Alphabet Holdings LLC (the sole member of GV 2019 GP, L.L.C.), XXVI Holdings Inc. (the sole member of Alphabet Holdings LLC), and Alphabet Inc. (the controlling stockholder of XXVI Holdings Inc.) may each be deemed to have sole power to dispose of the shares held directly by GV 2019, L.P. GV 2021 GP, L.P. (the general partner of GV 2021, L.P.), GV 2021 GP, L.L.C. (the general partner of GV 2021 GP, L.P.), Alphabet Holdings LLC (the sole member of GV 2021 GP, L.L.C.), XXVI Holdings Inc. (the sole member of Alphabet Holdings LLC), and Alphabet Inc. (the controlling stockholder of XXVI Holdings Inc.) may each be deemed to have sole power to dispose of the shares held directly by GV 2021, L.P.

⁽³⁾ Based on 111,251,660 shares of the Issuer’s Common Stock outstanding as of November 8, 2021 as disclosed in the Issuer’s Form 10-Q filed with the Securities and Exchange Commission on November 15, 2021.

Page 8 of 16

CUSIP No. 00534A102 13G

1	NAME OF REPORTING PERSONS   XXVI Holdings Inc.
2	CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP   (a)  ☐        (b)  ☒
3	SEC USE ONLY
4	CITIZENSHIP OR PLACE OF ORGANIZATION   Delaware

NUMBER OF SHARES  BENEFICIALLY  OWNED BY EACH REPORTING PERSON WITH:	5	SOLE VOTING POWER   5,680,785 (6)
	6	SHARED VOTING POWER   See response to row 5.
	7	SOLE DISPOSITIVE POWER.   5,680,785 (7)
	8	SHARED DISPOSITIVE POWER   See response to row 7.

9	AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON   5,680,785
10	CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES   ☐
11	PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9   5.11% (3)
12	TYPE OF REPORTING PERSON   CO

⁽⁶⁾ Consists of 5,200,545 shares of the Issuer’s Common Stock held directly by GV 2019, L.P. and 480,240 shares of the Issuer’s Common Stock held directly by GV 2021, L.P. GV 2019 GP, L.P. (the general partner of GV 2019, L.P.), GV 2019 GP, L.L.C. (the general partner of GV 2019 GP, L.P.), Alphabet Holdings LLC (the sole member of GV 2019 GP, L.L.C.), XXVI Holdings Inc. (the sole member of Alphabet Holdings LLC), and Alphabet Inc. (the controlling stockholder of XXVI Holdings Inc.) may each be deemed to have sole power to vote the shares held directly by GV 2019, L.P. GV 2021 GP, L.P. (the general partner of GV 2021, L.P.), GV 2021 GP, L.L.C. (the general partner of GV 2021 GP, L.P.), Alphabet Holdings LLC (the sole member of GV 2021 GP, L.L.C.), XXVI Holdings Inc. (the sole member of Alphabet Holdings LLC), and Alphabet Inc. (the controlling stockholder of XXVI Holdings Inc.) may each be deemed to have sole power to vote the shares held directly by GV 2021, L.P.

⁽⁷⁾ Consists of 5,200,545 shares of the Issuer’s Common Stock held directly by GV 2019, L.P. and 480,240 shares of the Issuer’s Common Stock held directly by GV 2021, L.P. GV 2019 GP, L.P. (the general partner of GV 2019, L.P.), GV 2019 GP, L.L.C. (the general partner of GV 2019 GP, L.P.), Alphabet Holdings LLC (the sole member of GV 2019 GP, L.L.C.), XXVI Holdings Inc. (the sole member of Alphabet Holdings LLC), and Alphabet Inc. (the controlling stockholder of XXVI Holdings Inc.) may each be deemed to have sole power to dispose of the shares held directly by GV 2019, L.P. GV 2021 GP, L.P. (the general partner of GV 2021, L.P.), GV 2021 GP, L.L.C. (the general partner of GV 2021 GP, L.P.), Alphabet Holdings LLC (the sole member of GV 2021 GP, L.L.C.), XXVI Holdings Inc. (the sole member of Alphabet Holdings LLC), and Alphabet Inc. (the controlling stockholder of XXVI Holdings Inc.) may each be deemed to have sole power to dispose of the shares held directly by GV 2021, L.P.

⁽³⁾ Based on 111,251,660 shares of the Issuer’s Common Stock outstanding as of November 8, 2021 as disclosed in the Issuer’s Form 10-Q filed with the Securities and Exchange Commission on November 15, 2021.

Page 9 of 16

CUSIP No. 00534A102 13G

1	NAME OF REPORTING PERSONS   Alphabet Inc.
2	CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP   (a)  ☐        (b)  ☒
3	SEC USE ONLY
4	CITIZENSHIP OR PLACE OF ORGANIZATION   Delaware

NUMBER OF SHARES  BENEFICIALLY  OWNED BY EACH REPORTING PERSON WITH:	5	SOLE VOTING POWER   5,680,785 (6)
	6	SHARED VOTING POWER   See response to row 5.
	7	SOLE DISPOSITIVE POWER.   5,680,785 (7)
	8	SHARED DISPOSITIVE POWER   See response to row 7.

9	AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON   5,680,785
10	CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES   ☐
11	PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9   5.11% (3)
12	TYPE OF REPORTING PERSON   CO, HC

⁽⁶⁾ Consists of 5,200,545 shares of the Issuer’s Common Stock held directly by GV 2019, L.P. and 480,240 shares of the Issuer’s Common Stock held directly by GV 2021, L.P. GV 2019 GP, L.P. (the general partner of GV 2019, L.P.), GV 2019 GP, L.L.C. (the general partner of GV 2019 GP, L.P.), Alphabet Holdings LLC (the sole member of GV 2019 GP, L.L.C.), XXVI Holdings Inc. (the sole member of Alphabet Holdings LLC), and Alphabet Inc. (the controlling stockholder of XXVI Holdings Inc.) may each be deemed to have sole power to vote the shares held directly by GV 2019, L.P. GV 2021 GP, L.P. (the general partner of GV 2021, L.P.), GV 2021 GP, L.L.C. (the general partner of GV 2021 GP, L.P.), Alphabet Holdings LLC (the sole member of GV 2021 GP, L.L.C.), XXVI Holdings Inc. (the sole member of Alphabet Holdings LLC), and Alphabet Inc. (the controlling stockholder of XXVI Holdings Inc.) may each be deemed to have sole power to vote the shares held directly by GV 2021, L.P.

⁽⁷⁾ Consists of 5,200,545 shares of the Issuer’s Common Stock held directly by GV 2019, L.P. and 480,240 shares of the Issuer’s Common Stock held directly by GV 2021, L.P. GV 2019 GP, L.P. (the general partner of GV 2019, L.P.), GV 2019 GP, L.L.C. (the general partner of GV 2019 GP, L.P.), Alphabet Holdings LLC (the sole member of GV 2019 GP, L.L.C.), XXVI Holdings Inc. (the sole member of Alphabet Holdings LLC), and Alphabet Inc. (the controlling stockholder of XXVI Holdings Inc.) may each be deemed to have sole power to dispose of the shares held directly by GV 2019, L.P. GV 2021 GP, L.P. (the general partner of GV 2021, L.P.), GV 2021 GP, L.L.C. (the general partner of GV 2021 GP, L.P.), Alphabet Holdings LLC (the sole member of GV 2021 GP, L.L.C.), XXVI Holdings Inc. (the sole member of Alphabet Holdings LLC), and Alphabet Inc. (the controlling stockholder of XXVI Holdings Inc.) may each be deemed to have sole power to dispose of the shares held directly by GV 2021, L.P.

⁽³⁾ Based on 111,251,660 shares of the Issuer’s Common Stock outstanding as of November 8, 2021 as disclosed in the Issuer’s Form 10-Q filed with the Securities and Exchange Commission on November 15, 2021.

Page 10 of 16

ITEM 1(A). NAME OF ISSUER

Adagio Therapeutics, Inc.

ITEM 1(B). ADDRESS OF ISSUER’S PRINCIPAL EXECUTIVE OFFICES:

1601 Trapelo Road, Suite 178

Waltham, MA 02451

ITEM 2(A). NAME OF PERSONS FILING:

This statement is filed by the following entities, collectively referred to as the “Reporting Persons”:

• GV 2019, L.P., a Delaware limited partnership

• GV 2019 GP, L.P., a Delaware limited partnership

• GV 2019 GP, L.L.C., a Delaware limited liability company

• GV 2021, L.P., a Delaware limited partnership

• GV 2021 GP, L.P., a Delaware limited partnership

• GV 2021 GP, L.L.C., a Delaware limited liability company

• Alphabet Holdings LLC, a Delaware limited liability company

• XXVI Holdings Inc., a Delaware corporation, and

• Alphabet Inc., a Delaware corporation

Each of GV 2019 GP, L.P. (the general partner of GV 2019, L.P.), GV 2019 GP, L.L.C. (the general partner of GV 2019 GP, L.P.), Alphabet Holdings LLC (the sole member of GV 2019 GP, L.L.C.), XXVI Holdings Inc. (the sole member of Alphabet Holdings LLC), and Alphabet Inc. (the controlling stockholder of XXVI Holdings Inc.) may be deemed to have sole power to vote or sole power to dispose of the securities owned directly by GV 2019, L.P.

Each of GV 2021 GP, L.P. (the general partner of GV 2021, L.P.), GV 2021 GP, L.L.C. (the general partner of GV 2021 GP, L.P.), Alphabet Holdings LLC (the sole member of GV 2021 GP, L.L.C.), XXVI Holdings Inc. (the sole member of Alphabet Holdings LLC), and Alphabet Inc. (the controlling stockholder of XXVI Holdings Inc.) may be deemed to have sole power to vote or sole power to dispose of the securities owned directly by GV 2021, L.P.

ITEM 2(B). ADDRESS OF PRINCIPAL BUSINESS OFFICE, OR, IF NONE, RESIDENCE:

The address of the principal business office for each of the Reporting Persons is:

1600 Amphitheatre Parkway

Mountain View, CA 94043

ITEM 2(C). CITIZENSHIP:

GV 2019, L.P. is a Delaware limited partnership, GV 2019 GP, L.P. is a Delaware limited partnership, GV 2019 GP, L.L.C. is a Delaware limited liability company, GV 2021, L.P. is a Delaware limited partnership, GV 2021 GP, L.P. is a Delaware limited partnership, GV 2021 GP, L.L.C. is a Delaware limited liability company, Alphabet Holdings LLC is a Delaware limited liability company, XXVI Holdings Inc. is a Delaware corporation, and Alphabet Inc. is a Delaware corporation.

Page 11 of 16

ITEM 2(D)/(E). TITLE OF CLASS OF SECURITIES AND CUSIP NUMBER:

Common Stock, par value $0.0001 per share

CUSIP # 00534A102

ITEM 3. Not Applicable.

ITEM 4. OWNERSHIP:

Provide the following information regarding the aggregate number and percentage of the class of securities of the issuer identified in Item 1.

(a) Amount beneficially owned:

See Row 9 of cover page for each Reporting Person.

(b) Percent of Class:

See Row 11 of cover page for each Reporting Person.

(c) Number of shares as to which such person has:

(i) Sole power to vote or to direct the vote:

See Row 5 of cover page for each Reporting Person.

(ii) Shared power to vote or to direct the vote:

See Row 6 of cover page for each Reporting Person.

(iii) Sole power to dispose or to direct the disposition of:

See Row 7 of cover page for each Reporting Person.

(iv) Shared power to dispose or to direct the disposition of:

See Row 8 of cover page for each Reporting Person.

ITEM 5. OWNERSHIP OF FIVE PERCENT OR LESS OF A CLASS:

Not Applicable.

ITEM 6. OWNERSHIP OF MORE THAN FIVE PERCENT ON BEHALF OF ANOTHER PERSON:

Under certain circumstances set forth in the limited partnership agreement of the limited partnership agreement of GV 2019, L.P., the limited partnership agreement of GV 2021, L.P., the limited partnership agreement of GV 2019 GP, L.P., the limited partnership agreement of GV 2021 GP, L.P., the limited liability company agreement of GV 2019 GP, L.L.C., and the limited liability company agreement of GV 2021 GP, L.L.C., the general and limited partners or members, as the case may be, of each of such entities may be deemed to have the right to receive dividends from, or the proceeds from, the sale of shares of the issuer owned by each such entity of which they are a general partner, limited partner, or member.

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ITEM 7. IDENTIFICATION AND CLASSIFICATION OF THE SUBSIDIARY WHICH ACQUIRED THE SECURITY BEING REPORTED ON BY THE PARENT HOLDING COMPANY:

Not Applicable.

ITEM 8. IDENTIFICATION AND CLASSIFICATION OF MEMBERS OF THE GROUP:

Not Applicable.

ITEM 9. NOTICE OF DISSOLUTION OF GROUP:

Not Applicable.

ITEM 10. CERTIFICATION:

Not Applicable.

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SIGNATURES

After reasonable inquiry and to the best of her or its knowledge and belief, each of the undersigned certifies that the information set forth in this statement is true, complete and correct.

Dated: February 11, 2022

GV 2019, L.P.
By: GV 2019 GP, L.P., its General Partner
By: GV 2019 GP, L.L.C., its General Partner
By: Alphabet Holdings LLC, its Sole Member
By:	/s/ Kathryn W. Hall
Name: Kathryn W. Hall
Title: Secretary
GV 2019 GP, L.P.
By: GV 2019 GP, L.L.C., its General Partner
By: Alphabet Holdings LLC, its Sole Member
By:	/s/ Kathryn W. Hall
Name: Kathryn W. Hall
Title: Secretary
GV 2019 GP, L.L.C.
By: Alphabet Holdings LLC, its Sole Member
By:	/s/ Kathryn W. Hall
Name: Kathryn W. Hall
Title: Secretary
GV 2021, L.P.
By: GV 2021 GP, L.P., its General Partner
By: GV 2021 GP, L.L.C., its General Partner
By: Alphabet Holdings LLC, its Sole Member
By:	/s/ Kathryn W. Hall
Name: Kathryn W. Hall
Title: Secretary
GV 2021 GP, L.P.
By: GV 2021 GP, L.L.C., its General Partner
By: Alphabet Holdings LLC, its Sole Member
By:	/s/ Kathryn W. Hall
Name: Kathryn W. Hall
Title: Secretary
GV 2021 GP, L.L.C.
By: Alphabet Holdings LLC, its Sole Member
By:	/s/ Kathryn W. Hall
Name: Kathryn W. Hall
Title: Secretary
Alphabet Holdings LLC
By:	/s/ Kathryn W. Hall
Name: Kathryn W. Hall
Title: Secretary

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XXVI Holdings Inc.
By:	/s/ Kathryn W. Hall
Name: Kathryn W. Hall
Title: Assistant Secretary
Alphabet Inc.
By:	/s/ Kathryn W. Hall
Name: Kathryn W. Hall
Title: Assistant Secretary

Page 15 of 16

EXHIBIT INDEX

Exhibit		Found on Sequentially Numbered Page
Exhibit A:	Agreement of Joint Filing	16

Page 16 of 16