Omega Therapeutics (OMGA) SC 13D Omega Therapeutics / Flagship Ventures Fund V ownership change

Exhibit 1

JOINT FILING AGREEMENT

The persons below hereby agree that the Schedule 13D to which this agreement is attached as an exhibit, as well as all future amendments to such Schedule 13D, shall be filed jointly on behalf of each of them. This agreement is intended to satisfy the requirements of Rule 13d-1(k)(1)(iii) under the Securities Exchange Act of 1934.

Dated: August 5, 2021

FLAGSHIP V VENTURELABS RX FUND, L.P.
By:	Flagship Ventures Fund V General Partner LLC
Its:	General Partner
By:	/s/ Noubar B. Afeyan, Ph.D.
Name:	Noubar B. Afeyan, Ph.D.
Title:	Manager
FLAGSHIP VENTURES FUND V, L.P.
By:	Flagship Ventures Fund V General Partner LLC
Its:	General Partner
By:	/s/ Noubar B. Afeyan, Ph.D.
Name:	Noubar B. Afeyan, Ph.D.
Title:	Manager
FLAGSHIP PIONEERING FUND VI, L.P.
By:	Flagship Pioneering Fund VI General Partner LLC
Its:	General Partner
By:	Flagship Pioneering, Inc.
Its:	Manager
By:	/s/ Noubar B. Afeyan, Ph.D.
Name:	Noubar B. Afeyan, Ph.D.
Title:	Chief Executive Officer, Sole Shareholder & Director
NUTRITIONAL HEALTH LTP FUND, L.P.
By:	Nutritional Health LTP Fund General Partner LLC
Its:	General Partner
By:	/s/ Noubar B. Afeyan, Ph.D.
Name:	Noubar B. Afeyan, Ph.D.
Title:	Manager
FLAGSHIP PIONEERING SPECIAL OPPORTUNITIES FUND II, L.P.
By:	Flagship Pioneering Special Opportunities Fund II General Partner LLC
Its:	General Partner
By:	Flagship Pioneering, Inc.
Its:	Manager

By:	/s/ Noubar B. Afeyan, Ph.D.
Name:	Noubar B. Afeyan, Ph.D.
Title:	Chief Executive Officer, Sole Shareholder & Director
FPN, L.P.
By:	FPN General Partner LLC
Its:	General Partner
By:	Flagship Pioneering, Inc.
Its:	Manager
By:	/s/ Noubar B. Afeyan, Ph.D.
Name:	Noubar B. Afeyan, Ph.D.
Title:	Chief Executive Officer, Sole Shareholder & Director
FLAGSHIP VENTURELABS V, LLC
By:	VentureLabs V Manager LLC
Its:	Manager
By:	Flagship Pioneering, Inc.
Its:	Manager
By:	/s/ Noubar B. Afeyan, Ph.D.
Name:	Noubar B. Afeyan, Ph.D.
Title:	Chief Executive Officer, Sole Shareholder & Director
FLAGSHIP VENTURES FUND V GENERAL PARTNER LLC
By:	/s/ Noubar B. Afeyan, Ph.D.
Name:	Noubar B. Afeyan, Ph.D.
Title:	Manager
FLAGSHIP PIONEERING FUND VI GENERAL PARTNER LLC
By:	Flagship Pioneering, Inc.
Its:	Manager
By:	/s/ Noubar B. Afeyan, Ph.D.
Name:	Noubar B. Afeyan, Ph.D.
Title:	Chief Executive Officer, Sole Shareholder & Director
FLAGSHIP PIONEERING FUND VI GENERAL PARTNER LLC
By:	Flagship Pioneering, Inc.
Its:	Manager
By:	/s/ Noubar B. Afeyan, Ph.D.
Name:	Noubar B. Afeyan, Ph.D.
Title:	Chief Executive Officer, Sole Shareholder & Director

NUTRITIONAL HEALTH LTP FUND GENERAL PARTNER LLC
By:	/s/ Noubar B. Afeyan, Ph.D.
Name:	Noubar B. Afeyan, Ph.D.
Title:	Manager
FLAGSHIP PIONEERING SPECIAL OPPORTUNITIES FUND II GENERAL PARTNER LLC
By:	Flagship Pioneering, Inc.
Its:	Manager
By:	/s/ Noubar B. Afeyan, Ph.D.
Name:	Noubar B. Afeyan, Ph.D.
Title:	Chief Executive Officer, Sole Shareholder & Director
FPN GENERAL PARTNER LLC
By:	Flagship Pioneering, Inc.
Its:	Manager
By:	/s/ Noubar B. Afeyan, Ph.D.
Name:	Noubar B. Afeyan, Ph.D.
Title:	Chief Executive Officer, Sole Shareholder & Director
VENTURELABS V MANAGER LLC
By:	Flagship Pioneering, Inc.
Its:	Manager
By:	/s/ Noubar B. Afeyan, Ph.D.
Name:	Noubar B. Afeyan, Ph.D.
Title:	Chief Executive Officer, Sole Shareholder & Director
FLAGSHIP PIONEERING, INC.
By:	/s/ Noubar B. Afeyan, Ph.D.
Name:	Noubar B. Afeyan, Ph.D.
Title:	Chief Executive Officer, Sole Shareholder & Director
/s/ Noubar B. Afeyan, Ph.D.
Name:	Noubar B. Afeyan, Ph.D.