| 25/08/2022, 09:24 Does The SPAC Have A Future In Biopharma? :: In Vivo https://invivo.pharmaintelligence.informa.com/IV146675/Does-The-SPAC-Have-A-Future-In-Biopharma 3/4 Read the full article here ❯ SPAC Mergers Are Viable Funding Tools, But The Test Is Yet To Come By Mandy Jackson 24 Nov 2021 Dozens of health care-focused special purpose acquisition corporations have gone public during the past two years but many biopharma frms that have merged with SPACs have not performed well to date, raising the question of how long the SPAC boom will last. He added: “This has been the preferred route for us; the advantage of our specifc deal is not only the committed capital that the deal brings, but also the team members that will be joining the business as part of the transaction. Given our confdence in our clinical programs, we also believe that we can create the most value as a public company and this unique SPAC deal presented the most timely and effcient path toward that goal.” Investors Reassess SPAC Risks But for every SPAC success story there seems to be another organization that sees the go-public-quick scheme blow up in its face. Several high-profle SPAC failures, both inside and outside of biopharma, have sullied the reputation of the whole operation. (Also see "Finance Watch: SPACs Lose Their Luster As Diffculties Mount" - Scrip, 18 Jan, 2022.) UK microbiome-based drug developer 4D Pharma Plc recently became one of the biopharma industry’s latest SPAC casualties, as the NASDAQ-listed company went into administration on 24 June. (Also see "4D Pharma Is Latest Biotech Casualty After Creditor Calls Time" - Scrip, 29 Jun, 2022.) This was just 18 months after it was listed following a $37.6m merger with a SPAC in February 2021. (Also see "4D Pharma Joins The SPAC Trend To Fund Its Keytruda-Boosting Biotherapeutic" - Scrip, 16 Feb, 2021.) The company agreed a senior secured credit facility of up to $30m with Oxford Finance in July last year, starting with an initial $12.5m sum, but failed to meet the necessary terms to qualify for further payments. It fnished its fnancial year with losses of £54.7m ($61.4m) and only £15.5m in cash. Biopharma companies also make up three out of the ten most short-lived SPAC deals of the year so far, as identifed by Reuters. Natural killer cell therapy developer Cytovia Therapeutics, Inc., which merged with Isleworth Healthcare Acquisition Corp., represented one of the shortest-lived SPAC deals of 2022. The frm went public in a $325m deal in April but was listed for only 65 days before withdrawing from the market. Aerami Therapeutics, a biopharma focused on the development of inhaled therapies for severe respiratory diseases, terminated its planned $250m merger with a SPAC known as FoxWayne Enterprises Acquisition Corp with 87 days between announcement and withdrawal. (Also see "Finance Watch: Biopharma IPO Market Silence Continues In The US" - Scrip, 15 Mar, 2022.) Meanwhile, UK psychedelic drug developer Eleusis Holdings pulled out of its $1.32bn deal with SPAC Sports Ventures Acquisition Corp 142 days from announcement. Cases such as these have created an environment where faith in the SPAC model, from both companies and investors, has come under strain. SEC Puts Its Foot Down The shaky ground on which SPACs currently stand has prompted the US SEC to propose new rules around their regulation. SEC chairman Gary Gensler said: “For traditional IPOs, Congress gave the SEC certain tools, which I generally see as falling into three buckets: disclosure; standards for marketing practices; and |