AstraZeneca Finance 424B2 Prospectus for primary offering

Exhibit 107

Calculation of Filing Fee Tables

FORM F-3

(Form Type)

AstraZeneca PLC

AstraZeneca Finance LLC

(Exact Name of Registrant as Specified in its Charter)

Table 1: Newly Registered Securities

The prospectus supplement to which this Exhibit is attached is a final prospectus for the related offerings. The maximum aggregate amount of those offerings is $4,987,937,500.

	Security Type	Security Class Title	Fee Calculation or Carry Forward Rule		Amount Registered		Proposed Maximum Offering Price Per Unit			Maximum Aggregate Offering Price		Fee Rate		Amount of Registration Fee
Newly Registered Securities
Fees to Be Paid	Debt	4.800% Notes due 2027		457(r)	$	1,250,000,000		99.832	%	$	1,247,900,000		$147.60 per million	$	184,190.04
Fees to Be Paid	Debt	Guarantees of 4.800% Notes due 2027		457(n)		—		—			—		—		—
Fees to Be Paid	Debt	4.850% Notes due 2029		457(r)	$	1,250,000,000		99.895	%	$	1,248,687,500		$147.60 per million	$	184,306.28
Fees to Be Paid	Debt	Guarantees of 4.850% Notes due 2029		457(n)		—		—			—		—		—
Fees to Be Paid	Debt	4.900% Notes due 2031		457(r)	$	1,000,000,000		99.684	%	$	996,840,000		$147.60 per million	$	147,133.58
Fees to Be Paid	Debt	Guarantees of 4.900% Notes due 2031		457(n)		—		—			—		—		—
Fees to Be Paid	Debt	5.000% Notes due 2034		457(r)	$	1,500,000,000		99.634	%	$	1,494,510,000		$147.60 per million	$	220,589.68
Fees to Be Paid	Debt	Guarantees of 5.000% Notes due 2034		457(n)		—		—			—		—		—
Total Offering Amounts					$	5,000,000,000		—		$	4,987,937,500			$	736,219.58
Total Fees Previously Paid														$	0
Total Fee Offsets														$	0
Net Fee Due														$	736,219.58