ADAR1 Capital Management 13F-HR Quarterly holdings report by institutional manager

The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE

OMB APPROVAL

OMB Number:		3235-0006
Expires:	Oct 31, 2018
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COLUMN 1	COLUMN 2	COLUMN 3	COLUMN 4	COLUMN 5			COLUMN 6	COLUMN 7	COLUMN 8
			VALUE	SHRS OR	SH/	PUT/	INVESTMENT	OTHER	VOTING AUTHORITY
NAME OF ISSUER	TITLE OF CLASS	CUSIP	(x$1000)	PRN AMT	PRN	CALL	DISCRETION	MANAGER	SOLE	SHARED	NONE
2SEVENTY BIO INC	COMMON STOCK	901384107	3,850	1,000	SH		SOLE		1,000	0	0
4D MOLECULAR THERAPEUTICS IN	COM	35104E100	41,980	2,000	SH		SOLE		2,000	0	0
89BIO INC	COM	282559103	44,536	5,560	SH		SOLE		5,560	0	0
99 ACQUISITION GROUP INC	UNIT 99/99/9999	65445K200	80,550	7,500	SH		SOLE		7,500	0	0
AB ACTIVE ETFS INC	ULTRA SHORT INCM	00039J103	505,150	10,000	SH		SOLE		10,000	0	0
ABBOTT LABS	COM	002824100	342,903	3,300	SH		SOLE		3,300	0	0
ABEONA THERAPEUTICS INC	COM NEW	00289Y206	479,650	113,125	SH		SOLE		113,125	0	0
ABIVAX SA	SPONSORED ADS	00370M103	356,940	27,000	SH		SOLE		27,000	0	0
ABSCI CORPORATION	COM	00091E109	5,231,469	1,698,529	SH		SOLE		1,698,529	0	0
ACADIA PHARMACEUTICALS INC	COM	004225108	21,125	1,300	SH		SOLE		1,300	0	0
ACASTI PHARMA INC	CL A	00430K865	2,801,947	959,571	SH		SOLE		959,571	0	0
ACELYRIN INC	COM	00445A100	222,798	50,521	SH		SOLE		50,521	0	0
ACHIEVE LIFE SCIENCES INC	COM	004468500	2,548,495	542,233	SH		SOLE		542,233	0	0
ACTINIUM PHARMACEUTICALS INC	COM	00507W206	555,984	75,133	SH		SOLE		75,133	0	0
ADDEX THERAPEUTICS LTD	SPONSORED ADS	00654J206	7,398	900	SH		SOLE		900	0	0
ADVERUM BIOTECHNOLOGIES INC	COM NEW	00773U207	77,518	11,300	SH		SOLE		11,300	0	0
AEROVATE THERAPEUTICS INC	COM	008064107	409,914	246,936	SH		SOLE		246,936	0	0
AEROVATE THERAPEUTICS INC	COM	008064107	4,150	2,500	SH	Call	SOLE		0	0	0
AI TRANSN ACQUISITION CORP	UNIT 99/99/9999	G01490138	78,750	7,500	SH		SOLE		7,500	0	0
AIMFINITY INVESTMENT CORP I	*W EXP 99/99/999	G0135E126	362	18,000	SH		SOLE		18,000	0	0
AKERO THERAPEUTICS INC	COM	00973Y108	598,394	25,507	SH		SOLE		25,507	0	0
ALECTOR INC	COM	014442107	886,712	195,311	SH		SOLE		195,311	0	0
ALGONQUIN PWR UTILS CORP	COM	015857105	87,900	15,000	SH		SOLE		15,000	0	0
ALKERMES PLC	SHS	G01767105	4,737,506	196,577	SH		SOLE		196,577	0	0
ALNYLAM PHARMACEUTICALS INC	COM	02043Q107	449,550	1,850	SH		SOLE		1,850	0	0
AMPHASTAR PHARMACEUTICALS IN	COM	03209R103	28,000	700	SH		SOLE		700	0	0
AMPLIFY ENERGY CORP NEW	COM	03212B103	19,852	2,928	SH		SOLE		2,928	0	0
AMYLYX PHARMACEUTICALS INC	COM	03237H101	203,881	107,306	SH		SOLE		107,306	0	0
AMYLYX PHARMACEUTICALS INC	COM	03237H101	19,000	10,000	SH	Call	SOLE		0	0	0
ANAPTYSBIO INC	COM	032724106	3,904,323	155,799	SH		SOLE		155,799	0	0
ANAPTYSBIO INC	COM	032724106	37,590	1,500	SH	Call	SOLE		0	0	0
ANGIODYNAMICS INC	COM	03475V101	870,365	143,862	SH		SOLE		143,862	0	0
APELLIS PHARMACEUTICALS INC	COM	03753U106	792,134	20,650	SH		SOLE		20,650	0	0
APELLIS PHARMACEUTICALS INC	COM	03753U106	3,836	100	SH	Call	SOLE		0	0	0
APOGEE THERAPEUTICS INC	COM	03770N101	1,608,431	40,875	SH		SOLE		40,875	0	0
APPLIED THERAPEUTICS INC	COM	03828A101	1,497,795	320,727	SH		SOLE		320,727	0	0
ARBUTUS BIOPHARMA CORP	COM	03879J100	10,163,813	3,289,260	SH		SOLE		3,289,260	0	0
ARCA BIOPHARMA INC	COM	00211Y506	324,309	84,676	SH		SOLE		84,676	0	0
ARCELLX INC	COMMON STOCK	03940C100	5,519	100	SH		SOLE		100	0	0
ARCUTIS BIOTHERAPEUTICS INC	COM	03969K108	14,462	1,555	SH		SOLE		1,555	0	0
ARDELYX INC	COM	039697107	518,700	70,000	SH		SOLE		70,000	0	0
ARROWHEAD PHARMACEUTICALS IN	COM	04280A100	153,341	5,900	SH		SOLE		5,900	0	0
ARVINAS INC	COM	04335A105	862,488	32,400	SH		SOLE		32,400	0	0
ARYA SCIENCES ACQU CORP IV	CL A	G31659108	613,955	53,527	SH		SOLE		53,527	0	0
ASCENDIS PHARMA A/S	SPONSORED ADR	04351P101	6,991,248	51,263	SH		SOLE		51,263	0	0
ASTRAZENECA PLC	SPONSORED ADR	046353108	7,799	100	SH		SOLE		100	0	0
ASTRIA THERAPEUTICS INC	COM	04635X102	1,257,238	138,158	SH		SOLE		138,158	0	0
AURA BIOSCIENCES INC	COM	05153U107	1,536,472	203,237	SH		SOLE		203,237	0	0
AVANGRID INC	COM	05351W103	817,190	23,000	SH		SOLE		23,000	0	0
AXSOME THERAPEUTICS INC	COM	05464T104	24,150	300	SH		SOLE		300	0	0
BAUSCH PLUS LOMB CORP	COMMON SHARES	071705107	92,928	6,400	SH		SOLE		6,400	0	0
BEAM THERAPEUTICS INC	COM	07373V105	1,705,704	72,800	SH		SOLE		72,800	0	0
BEIGENE LTD	SPONSORED ADR	07725L102	1,583,637	11,100	SH		SOLE		11,100	0	0
BEYOND AIR INC	COM	08862L103	658,338	1,225,270	SH		SOLE		1,225,270	0	0
BIOCRYST PHARMACEUTICALS INC	COM	09058V103	181,692	29,400	SH		SOLE		29,400	0	0
BLACK HAWK ACQUISITION CORP	UNIT 99/99/9999	G1148A127	154,800	15,000	SH		SOLE		15,000	0	0
BLUEBIRD BIO INC	COM	09609G100	5,905	6,000	SH		SOLE		6,000	0	0
BOLT BIOTHERAPEUTICS INC	COM	097702104	139,499	185,999	SH		SOLE		185,999	0	0
BRIDGEBIO PHARMA INC	COM	10806X102	32,031,558	1,264,570	SH		SOLE		1,264,570	0	0
BRIDGEBIO PHARMA INC	COM	10806X102	93,721	3,700	SH	Call	SOLE		0	0	0
BRIDGEBIO PHARMA INC	COM	10806X102	30,396	1,200	SH	Put	SOLE		1,200	0	0
CAPRICOR THERAPEUTICS INC	COM NEW	14070B309	97,308	20,400	SH	Put	SOLE		20,400	0	0
CARA THERAPEUTICS INC	COM	140755109	41,143	159,469	SH		SOLE		159,469	0	0
CASI PHARMACEUTICALS INC	ORD SHS	G1933S101	45,320	8,240	SH		SOLE		8,240	0	0
CELCUITY INC	COM	15102K100	22,932	1,400	SH		SOLE		1,400	0	0
CELLDEX THERAPEUTICS INC NEW	COM NEW	15117B202	11,214	303	SH		SOLE		303	0	0
CELLECTAR BIOSCIENCES INC	COM NEW	15117F807	1,705,235	682,094	SH		SOLE		682,094	0	0
CENTESSA PHARMACEUTICALS PLC	SPONSORED ADS	152309100	2,286,369	253,197	SH		SOLE		253,197	0	0
CEREVEL THERAPEUTICS HLDNG I	COM	15678U128	3,817,082	93,350	SH		SOLE		93,350	0	0
CEREVEL THERAPEUTICS HLDNG I	COM	15678U128	2,052,678	50,200	SH	Put	SOLE		50,200	0	0
CETUS CAP ACQUISITION CORP	RIGHT 03/31/2024	15719Y121	1,424	4,999	SH		SOLE		4,999	0	0
CETUS CAP ACQUISITION CORP	*W EXP 01/31/202	15719Y113	130	5,000	SH		SOLE		5,000	0	0
CG ONCOLOGY INC	COM	156944100	405,674	12,850	SH		SOLE		12,850	0	0
CHIMERIX INC	COM	16934W106	156,129	178,229	SH		SOLE		178,229	0	0
COGENT COMMUNICATIONS HLDGS	COM NEW	19239V302	225,760	4,000	SH		SOLE		4,000	0	0
CONTEXT THERAPEUTICS INC	COM	21077P108	1,293,548	645,161	SH		SOLE		645,161	0	0
CORBUS PHARMACEUTICALS HLDGS	COM NEW	21833P301	543,000	12,000	SH		SOLE		12,000	0	0
CORTEVA INC	COM	22052L104	614,916	11,400	SH		SOLE		11,400	0	0
CRINETICS PHARMACEUTICALS IN	COM	22663K107	3,352,532	74,850	SH		SOLE		74,850	0	0
CULLINAN THERAPEUTICS INC	COM	230031106	928,872	53,261	SH		SOLE		53,261	0	0
CYTOKINETICS INC	COM NEW	23282W605	46,262,243	853,862	SH		SOLE		853,862	0	0
CYTOKINETICS INC	COM NEW	23282W605	5,418	100	SH	Call	SOLE		0	0	0
CYTOMX THERAPEUTICS INC	COM	23284F105	698,047	572,170	SH		SOLE		572,170	0	0
DAY ONE BIOPHARMACEUTICALS I	COM	23954D109	483,678	35,100	SH		SOLE		35,100	0	0
DELCATH SYS INC	COM NEW	24661P807	1,660,164	198,347	SH		SOLE		198,347	0	0
DENALI THERAPEUTICS INC	COM	24823R105	882,360	38,000	SH		SOLE		38,000	0	0
EA SERIES TRUST	ALPHA ARCH 1-3	02072L565	37,895,032	351,482	SH		SOLE		351,482	0	0
EAGLE PHARMACEUTICALS INC	COM	269796108	123,200	22,000	SH		SOLE		22,000	0	0
ECD AUTOMOTIVE DESIGN INC	*W EXP 12/12/202	27877D112	652	32,596	SH		SOLE		32,596	0	0
EDGEWISE THERAPEUTICS INC	COM	28036F105	7,863,310	436,608	SH		SOLE		436,608	0	0
ELEVATION ONCOLOGY INC	COM	28623U101	229,303	84,927	SH		SOLE		84,927	0	0
ELIEM THERAPEUTICS INC	COM	28658R106	694,611	97,695	SH		SOLE		97,695	0	0
EMBRACE CHANGE ACQUISITN COR	RIGHT 10/25/2026	G3034H141	2,484	18,000	SH		SOLE		18,000	0	0
EMBRACE CHANGE ACQUISITN COR	*W EXP 10/25/202	G3034H125	378	18,000	SH		SOLE		18,000	0	0
ENDEAVOR GROUP HLDGS INC	CL A COM	29260Y109	286,923	10,615	SH		SOLE		10,615	0	0
ENGENE HOLDINGS INC	COM	29286M105	5,658	600	SH		SOLE		600	0	0
ENVVENO MEDICAL CORPORATION	COM	29415J106	1,059,072	201,728	SH		SOLE		201,728	0	0
EQUILLIUM INC	COM	29446K106	97,585	140,775	SH		SOLE		140,775	0	0
EQUILLIUM INC	COM	29446K106	6,100	8,800	SH	Call	SOLE		0	0	0
ERASCA INC	COM	29479A108	7,316	3,100	SH		SOLE		3,100	0	0
ETON PHARMACEUTICALS INC	COM	29772L108	3,948	1,200	SH		SOLE		1,200	0	0
EVOTEC AG	SPONSORED ADS	30050E105	45,120	9,400	SH		SOLE		9,400	0	0
EXACT SCIENCES CORP	COM	30063P105	25,350	600	SH		SOLE		600	0	0
FORTE BIOSCIENCES INC	COM	34962G109	85,522	159,258	SH		SOLE		159,258	0	0
FOUR LEAF ACQUISITION CORP	*W EXP 03/15/202	35088F115	360	7,987	SH		SOLE		7,987	0	0
FULCRUM THERAPEUTICS INC	COM	359616109	2,283,888	368,369	SH		SOLE		368,369	0	0
FULCRUM THERAPEUTICS INC	COM	359616109	124,000	20,000	SH	Call	SOLE		0	0	0
FUTURETECH II ACQUISITION CO	*W EXP 08/18/202	36119D111	483	30,000	SH		SOLE		30,000	0	0
GERON CORP	COM	374163103	381,600	90,000	SH		SOLE		90,000	0	0
GH RESEARCH PLC	ORDINARY SHARES	G3855L106	21,571	1,850	SH		SOLE		1,850	0	0
GLOBAL STAR ACQUISITION INC	RIGHT 06/21/2024	37962G128	14,800	118,400	SH		SOLE		118,400	0	0
GLOBAL STAR ACQUISITION INC	*W EXP 07/15/202	37962G110	2,976	120,000	SH		SOLE		120,000	0	0
GLYCOMIMETICS INC	COM	38000Q102	38,016	135,000	SH		SOLE		135,000	0	0
GLYCOMIMETICS INC	COM	38000Q102	38,016	135,000	SH	Put	SOLE		135,000	0	0
GOSSAMER BIO INC	COM	38341P102	479,845	532,628	SH		SOLE		532,628	0	0
GOSSAMER BIO INC	COM	38341P102	18,018	20,000	SH	Call	SOLE		0	0	0
GRAIL INC	COM	384747101	328,933	21,401	SH		SOLE		21,401	0	0
GREENLIGHT CAPITAL RE LTD	CLASS A	G4095J109	162,244	12,385	SH		SOLE		12,385	0	0
GUARDANT HEALTH INC	COM	40131M109	981,920	34,000	SH		SOLE		34,000	0	0
HELIX ACQUISITION CORP II	CL A ORD SHS	G4444H101	4,130,290	404,138	SH		SOLE		404,138	0	0
HIMS & HERS HEALTH INC	COM CL A	433000106	18,979	940	SH		SOLE		940	0	0
HOWARD HUGHES HOLDINGS INC	COM	44267T102	64,820	1,000	SH		SOLE		1,000	0	0
IBIO INC	CON NEW	451033708	1,202,700	570,000	SH		SOLE		570,000	0	0
ICHOR HOLDINGS	SHS	G4740B105	4,163	108	SH		SOLE		108	0	0
IDEAYA BIOSCIENCES INC	COM	45166A102	10,533	300	SH		SOLE		300	0	0
IKENA ONCOLOGY INC	COM	45175G108	77,030	46,685	SH		SOLE		46,685	0	0
IMMUNOVANT INC	COM	45258J102	12,580,735	476,543	SH		SOLE		476,543	0	0
INDIVIOR PLC	ORD	G4766E116	1,128,513	70,007	SH		SOLE		70,007	0	0
INSMED INC	COM PAR $.01	457669307	2,828,539	42,217	SH		SOLE		42,217	0	0
INSMED INC	COM PAR $.01	457669307	10,050,000	150,000	SH	Call	SOLE		0	0	0
INSMED INC	COM PAR $.01	457669307	13,453,600	200,800	SH	Put	SOLE		200,800	0	0
INTELLIGENT BIO SOLUTIONS IN	COM	36151G600	207,840	108,250	SH		SOLE		108,250	0	0
INVESCO QQQ TR	UNIT SER 1	46090E103	1,437,330	3,000	SH	Put	SOLE		3,000	0	0
IONIS PHARMACEUTICALS INC	COM	462222100	71,490	1,500	SH		SOLE		1,500	0	0
IOVANCE BIOTHERAPEUTICS INC	COM	462260100	179,648	22,400	SH		SOLE		22,400	0	0
IRON HORSE ACQUISITIONS CORP	UNIT 10/15/2028	462837204	257,250	25,000	SH		SOLE		25,000	0	0
ISHARES TR	20 YR TR BD ETF	464287432	183,560	2,000	SH		SOLE		2,000	0	0
ISHARES TR	SHORT TREAS BD	464288679	2,707,250	24,500	SH		SOLE		24,500	0	0
ISHARES TR	RUSSELL 2000 ETF	464287655	608,670	3,000	SH	Put	SOLE		3,000	0	0
ITEOS THERAPEUTICS INC	COM	46565G104	890,400	60,000	SH		SOLE		60,000	0	0
J P MORGAN EXCHANGE TRADED F	ULTRA SHRT INC	46641Q837	2,725,380	54,000	SH		SOLE		54,000	0	0
JANUX THERAPEUTICS INC	COM	47103J105	330,554	7,891	SH		SOLE		7,891	0	0
JVSPAC ACQUISITION CORP	UNIT 03/11/2024	G5212E139	312,600	30,000	SH		SOLE		30,000	0	0
KALA BIO INC	COM NEW	483119202	2,170,015	306,067	SH		SOLE		306,067	0	0
KALVISTA PHARMACEUTICALS INC	COM	483497103	141,596	12,020	SH		SOLE		12,020	0	0
KEEN VISION ACQUISITION CORP	UNIT 99/99/9999	G52443101	792,750	75,000	SH		SOLE		75,000	0	0
KENSINGTON CAPITAL ACQUISITI	SHS CL A	G5251K103	94,222	8,500	SH		SOLE		8,500	0	0
KEROS THERAPEUTICS INC	COM	492327101	25,085,461	548,916	SH		SOLE		548,916	0	0
KEZAR LIFE SCIENCES INC	COM	49372L100	651,899	1,086,498	SH		SOLE		1,086,498	0	0
KINIKSA PHARMACEUTICALS INTL	ORD SHS CL A	G52694109	2,134,149	114,309	SH		SOLE		114,309	0	0
KIORA PHARMACEUTICALS INC	COM	49721T507	724,903	172,596	SH		SOLE		172,596	0	0
KOHLS CORP	COM	500255104	45,980	2,000	SH		SOLE		2,000	0	0
KORRO BIO INC	COM	500946108	244,203	7,210	SH		SOLE		7,210	0	0
KYMERA THERAPEUTICS INC	COM	501575104	1,511,186	50,626	SH		SOLE		50,626	0	0
LEXARIA BIOSCIENCE CORP	COM NEW	52886N406	2,627	945	SH		SOLE		945	0	0
LEXEO THERAPEUTICS INC	COM	52886X107	20,852	1,300	SH		SOLE		1,300	0	0
LIGAND PHARMACEUTICALS INC	COM NEW	53220K504	74,991	890	SH		SOLE		890	0	0
MASIMO CORP	COM	574795100	4,786	38	SH		SOLE		38	0	0
MERCK & CO INC	COM	58933Y105	9,377,850	75,750	SH		SOLE		75,750	0	0
MEREO BIOPHARMA GROUP PLC	SPON ADS	589492107	199,440	55,400	SH		SOLE		55,400	0	0
MERUS N V	COM	N5749R100	1,588,714	26,850	SH		SOLE		26,850	0	0
MILESTONE PHARMACEUTICALS IN	COM	59935V107	267,247	202,460	SH		SOLE		202,460	0	0
MINERALYS THERAPEUTICS INC	COM	603170101	296,782	25,366	SH		SOLE		25,366	0	0
MITEK SYS INC	COM NEW	606710200	62,608	5,600	SH		SOLE		5,600	0	0
MKS INSTRS INC	COM	55306N104	261,160	2,000	SH		SOLE		2,000	0	0
MODERNA INC	COM	60770K107	593,750	5,000	SH	Call	SOLE		0	0	0
MOONLAKE IMMUNOTHERAPEUTICS	CLASS A ORD	61559X104	211,056	4,800	SH		SOLE		4,800	0	0
MOVANO INC	COM	62459M107	386,925	1,407,000	SH		SOLE		1,407,000	0	0
NCR ATLEOS CORPORATION	COM SHS	63001N106	27,020	1,000	SH		SOLE		1,000	0	0
NCR VOYIX CORPORATION	COM	62886E108	24,700	2,000	SH		SOLE		2,000	0	0
NEUROGENE INC	COM	64135M105	45,597	1,253	SH		SOLE		1,253	0	0
NEXTCURE INC	COM	65343E108	141,532	89,014	SH		SOLE		89,014	0	0
NOVO-NORDISK A S	ADR	670100205	28,548	200	SH		SOLE		200	0	0
NURIX THERAPEUTICS INC	COM	67080M103	73,045	3,500	SH		SOLE		3,500	0	0
NUVEI CORPORATION	SUB VTG SHS	67079A102	161,900	5,000	SH		SOLE		5,000	0	0
OAK WOODS ACQUISITION CORP	CL A	67190B104	326,400	30,000	SH		SOLE		30,000	0	0
OAK WOODS ACQUISITION CORP	RIGHT 03/23/2028	67190B120	7,500	30,000	SH		SOLE		30,000	0	0
OAK WOODS ACQUISITION CORP	*W EXP 99/99/999	67190B112	750	30,000	SH		SOLE		30,000	0	0
OCULAR THERAPEUTIX INC	COM	67576A100	225,036	32,900	SH		SOLE		32,900	0	0
OKLO INC	COM CL A	02156V109	8,470	1,000	SH		SOLE		1,000	0	0
OLEMA PHARMACEUTICALS INC	COM	68062P106	217,222	20,076	SH		SOLE		20,076	0	0
OMNIAB INC	COM	68218J103	2,672,100	712,560	SH		SOLE		712,560	0	0
OPTINOSE INC	COM	68404V100	3,120	3,000	SH		SOLE		3,000	0	0
OPTION CARE HEALTH INC	COM NEW	68404L201	332,400	12,000	SH		SOLE		12,000	0	0
ORGANON & CO	COMMON STOCK	68622V106	51,750	2,500	SH		SOLE		2,500	0	0
OVID THERAPEUTICS INC	COM	690469101	14,761	19,190	SH		SOLE		19,190	0	0
PASITHEA THERAPEUTICS CORP	COM NEW	70261F202	140,161	27,696	SH		SOLE		27,696	0	0
PERCEPTIVE CAP SOLUTIONS COR	CL A ORD SHS	G70077105	7,545,000	750,000	SH		SOLE		750,000	0	0
PERRIGO CO PLC	SHS	G97822103	28,248	1,100	SH		SOLE		1,100	0	0
PERSPECTIVE THERAPEUTICS INC	COM NEW	46489V302	697,750	69,985	SH		SOLE		69,985	0	0
PFIZER INC	COM	717081103	1,117,801	39,950	SH		SOLE		39,950	0	0
PGIM ETF TR	PGIM ULTRA SH BD	69344A107	497,000	10,000	SH		SOLE		10,000	0	0
PHARVARIS N V	COM	N69605108	37,600	2,000	SH		SOLE		2,000	0	0
PIMCO ETF TR	25YR+ ZERO U S	72201R882	225,270	3,000	SH		SOLE		3,000	0	0
PLIANT THERAPEUTICS INC	COM	729139105	107,500	10,000	SH		SOLE		10,000	0	0
PMV PHARMACEUTICALS INC	COM	69353Y103	81,000	50,000	SH		SOLE		50,000	0	0
POLYPID LTD	COM	M8001Q126	446,985	103,950	SH		SOLE		103,950	0	0
PONO CAP TWO INC	*W EXP 99/99/999	73245B115	1,406	19,800	SH		SOLE		19,800	0	0
PROTAGONIST THERAPEUTICS INC	COM	74366E102	55,576,244	1,603,932	SH		SOLE		1,603,932	0	0
PROTHENA CORP PLC	SHS	G72800108	123,592	5,988	SH		SOLE		5,988	0	0
PURETECH HEALTH PLC	ADS	746237106	17,500	700	SH		SOLE		700	0	0
PYXIS ONCOLOGY INC	COMMON STOCK	747324101	33,100	10,000	SH		SOLE		10,000	0	0
Q32 BIO INC	COM	746964105	2,809,247	156,504	SH		SOLE		156,504	0	0
QUINCE THERAPEUTICS INC	COM	22053A107	69,718	92,958	SH		SOLE		92,958	0	0
RALLYBIO CORP	COM	75120L100	15,008	11,200	SH		SOLE		11,200	0	0
RAPT THERAPEUTICS INC	COM	75382E109	22,875	7,500	SH		SOLE		7,500	0	0
REGENXBIO INC	COM	75901B107	31,590	2,700	SH		SOLE		2,700	0	0
RELMADA THERAPEUTICS INC	COM	75955J402	151,803	50,601	SH		SOLE		50,601	0	0
RENOVORX INC	COM NEW	75989R107	401,421	355,240	SH		SOLE		355,240	0	0
REZOLUTE INC	COM NEW	76200L309	8,875,037	2,063,962	SH		SOLE		2,063,962	0	0
RHYTHM PHARMACEUTICALS INC	COM	76243J105	533,780	13,000	SH		SOLE		13,000	0	0
ROCKET PHARMACEUTICALS INC	COM	77313F106	2,153	100	SH		SOLE		100	0	0
ROIVANT SCIENCES LTD	SHS	G76279101	43,865,595	4,150,009	SH		SOLE		4,150,009	0	0
ROYALTY PHARMA PLC	SHS CLASS A	G7709Q104	31,151,725	1,181,332	SH		SOLE		1,181,332	0	0
SANOFI	SPONSORED ADR	80105N105	441,532	9,100	SH		SOLE		9,100	0	0
SAREPTA THERAPEUTICS INC	COM	803607100	703,100	4,450	SH		SOLE		4,450	0	0
SAVARA INC	COM	805111101	2,674,300	663,598	SH		SOLE		663,598	0	0
SAVARA INC	COM	805111101	20,150	5,000	SH	Call	SOLE		0	0	0
SAVARA INC	COM	805111101	44,330	11,000	SH	Put	SOLE		11,000	0	0
SCHOLAR ROCK HLDG CORP	COM	80706P103	99,960	12,000	SH		SOLE		12,000	0	0
SILENCE THERAPEUTICS PLC	ADS	82686Q101	765,510	40,290	SH		SOLE		40,290	0	0
SOLENO THERAPEUTICS INC	COM	834203309	1,629,103	39,929	SH		SOLE		39,929	0	0
SOLID BIOSCIENCES INC	COM NEW	83422E204	8,053,793	1,420,422	SH		SOLE		1,420,422	0	0
SPDR S&P 500 ETF TR	TR UNIT	78462F103	4,353,760	8,000	SH	Put	SOLE		8,000	0	0
SPDR SER TR	BLOOMBERG 1-3 MO	78468R663	2,982,850	32,500	SH		SOLE		32,500	0	0
SPERO THERAPEUTICS INC	COM	84833T103	1,194,608	918,929	SH		SOLE		918,929	0	0
SPRUCE BIOSCIENCES INC	COM	85209E109	183,895	355,216	SH		SOLE		355,216	0	0
SPYRE THERAPEUTICS INC	COM NEW	00773J202	827,082	35,180	SH		SOLE		35,180	0	0
SSGA ACTIVE ETF TR	ULT SHT TRM BD	78467V707	1,929,771	47,684	SH		SOLE		47,684	0	0
STEVANATO GROUP S P A	ORD SHS	T9224W109	495,180	27,000	SH		SOLE		27,000	0	0
STRUCTURE THERAPEUTICS INC	SPONSORED ADS	86366E106	59,533	1,516	SH		SOLE		1,516	0	0
TARGET HOSPITALITY CORP	COM	87615L107	989,682	113,626	SH		SOLE		113,626	0	0
TAYSHA GENE THERAPIES INC	COM SHS	877619106	561,792	250,800	SH		SOLE		250,800	0	0
TECTONIC THERAPEUTIC INC	COM	878972108	5,877,781	356,878	SH		SOLE		356,878	0	0
TERNS PHARMACEUTICALS INC	COM	880881107	102,150	15,000	SH		SOLE		15,000	0	0
TEVA PHARMACEUTICAL INDS LTD	SPONSORED ADS	881624209	1,675,716	103,121	SH		SOLE		103,121	0	0
TG THERAPEUTICS INC	COM	88322Q108	99,428	5,589	SH		SOLE		5,589	0	0
THERAPEUTICSMD INC	COM NEW	88338N206	434,958	270,160	SH		SOLE		270,160	0	0
THUNDER PWR HLDGS INC	COM	31561T102	2,475	1,500	SH		SOLE		1,500	0	0
TMT ACQUISITION CORP	SHS	G89229119	549,000	50,000	SH		SOLE		50,000	0	0
TMT ACQUISITION CORP	RIGHT 03/27/2028	G89229135	17,016	49,900	SH		SOLE		49,900	0	0
TOURMALINE BIO INC	COM	89157D105	270,832	21,060	SH		SOLE		21,060	0	0
TRIPADVISOR INC	COM	896945201	391,820	22,000	SH		SOLE		22,000	0	0
TYRA BIOSCIENCES INC	COM	90240B106	4,797	300	SH		SOLE		300	0	0
ULTRA CLEAN HLDGS INC	COM	90385V107	49,000	1,000	SH		SOLE		1,000	0	0
UNIQURE NV	SHS	N90064101	5,477,588	1,222,676	SH		SOLE		1,222,676	0	0
VANGUARD BD INDEX FDS	VANGUARD ULTRA	92203C303	2,733,801	55,206	SH		SOLE		55,206	0	0
VAXART INC	COM NEW	92243A200	630,978	945,568	SH		SOLE		945,568	0	0
VAXCYTE INC	COM	92243G108	924,998	12,250	SH		SOLE		12,250	0	0
VENTYX BIOSCIENCES INC	COM	92332V107	29,926	12,955	SH		SOLE		12,955	0	0
VERA THERAPEUTICS INC	CL A	92337R101	39,038	1,079	SH		SOLE		1,079	0	0
VERVE THERAPEUTICS INC	COM	92539P101	214,720	44,000	SH		SOLE		44,000	0	0
VIKING THERAPEUTICS INC	COM	92686J106	4,835,943	91,227	SH		SOLE		91,227	0	0
VIR BIOTECHNOLOGY INC	COM	92764N102	979,000	110,000	SH		SOLE		110,000	0	0
VIRIDIAN THERAPEUTICS INC	COM	92790C104	104,080	8,000	SH		SOLE		8,000	0	0
VOYAGER THERAPEUTICS INC	COM	92915B106	147,395	18,634	SH		SOLE		18,634	0	0
VYNE THERAPEUTICS INC	COM	92941V308	337,297	171,217	SH		SOLE		171,217	0	0
WAVE LIFE SCIENCES LTD	SHS	Y95308105	382,488	76,651	SH		SOLE		76,651	0	0
WEST PHARMACEUTICAL SVSC INC	COM	955306105	293,157	890	SH		SOLE		890	0	0
WISDOMTREE TR	FLOATNG RAT TREA	97717Y527	2,666,430	53,000	SH		SOLE		53,000	0	0
XENON PHARMACEUTICALS INC	COM	98420N105	183,253	4,700	SH		SOLE		4,700	0	0
XERIS BIOPHARMA HOLDINGS INC	COM	98422E103	2,250	1,000	SH		SOLE		1,000	0	0
XILIO THERAPEUTICS INC	COM	98422T100	1,421	1,500	SH		SOLE		1,500	0	0
ZAI LAB LTD	ADR	98887Q104	381,260	22,000	SH		SOLE		22,000	0	0
ZEVRA THERAPEUTICS INC	COM NEW	488445206	9,800	2,000	SH		SOLE		2,000	0	0
ZYVERSA THERAPEUTICS INC	COM	98987D300	36,088	9,598	SH		SOLE		9,598	0	0