The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||||||
UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | ||||
VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | |||||
NAME OF ISSUER | TITLE OF CLASS | CUSIP | (x$1000) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
ABEONA THERAPEUTICS INC | COMM | 00289Y206 | 2,645,853 | 624,022 | SH | DFND | 1 | 215,438 | 408,584 | 0 | |
ACHIEVE LIFE SCIENCES INC | COMM | 004468500 | 11,529,532 | 2,453,092 | SH | DFND | 1 | 2,235,247 | 217,845 | 0 | |
AKERO THERAPEUTICS INC | COMM | 00973Y108 | 7,689,062 | 327,752 | SH | DFND | 1 | 115,275 | 212,477 | 0 | |
APPLIED THERAPEUTICS INC | COMM | 03828A101 | 30,671,897 | 6,567,858 | SH | DFND | 1 | 3,750,353 | 2,817,505 | 0 | |
ARDELYX INC | COMM | 039697107 | 6,851,160 | 924,583 | SH | DFND | 1 | 326,583 | 598,000 | 0 | |
AVIDITY BIOSCIENCES INC | COMM | 05370A108 | 7,291,725 | 178,500 | SH | DFND | 1 | 53,500 | 125,000 | 0 | |
CHINOOK THERAPEUTICS | COMM | 169CVR016 | 9,750 | 79,357 | SH | DFND | 1 | 54,357 | 25,000 | 0 | |
CYBIN INC | COMM | 23256X100 | 230,350 | 850,000 | SH | DFND | 1 | 350,000 | 500,000 | 0 | |
EIGER BIOPHARMACEUTICALS | COMM | 28249U204 | 1,851,720 | 146,381 | SH | DFND | 1 | 56,381 | 90,000 | 0 | |
FULCRUM THERAPEUTICS INC | COMM | 359616109 | 4,650,000 | 750,000 | SH | DFND | 1 | 285,000 | 465,000 | 0 | |
KURA ONCOLOGY INC | COMM | 50127T109 | 2,676,700 | 130,000 | SH | DFND | 1 | 50,000 | 80,000 | 0 | |
KYMERA THERAPEUTICS INC | COMM | 501575104 | 1,682,316 | 56,359 | SH | DFND | 1 | 25,844 | 30,515 | 0 | |
MADRIGAL PHARMACEUTICALS | COMM | 558868105 | 12,055,845 | 43,032 | SH | DFND | 1 | 19,738 | 23,294 | 0 | |
PHATHOM PHARMACEUTICALS I | COMM | 71722W107 | 8,960,248 | 869,927 | SH | DFND | 1 | 347,992 | 521,935 | 0 | |
SYNDAX PHARMACEUTICALS IN | COMM | 87164F105 | 1,709,307 | 83,259 | SH | DFND | 1 | 33,259 | 50,000 | 0 | |
TREVI THERAPEUTICS INC | COMM | 89532M101 | 774,800 | 260,000 | SH | DFND | 1 | 60,000 | 200,000 | 0 | |
TSCAN THERAPEUTICS INC | COMM | 89854M101 | 12,209,763 | 2,087,139 | SH | DFND | 1 | 1,040,223 | 1,046,916 | 0 | |
VERRICA PHARMACEUTICALS I | COMM | 92511W108 | 3,097,791 | 424,937 | SH | DFND | 1 | 144,937 | 280,000 | 0 | |
MAAT PHARMA SACA | COMM | 00BNRR5C1 | 9,752 | 1,362 | SH | DFND | 1 | 0 | 1,362 | 0 | |
TELESAT CORP | COMM | 879512309 | 3,328,607 | 365,781 | SH | DFND | 1 | 0 | 365,781 | 0 | |
KAYNE ANDERSON ENERGY INF | COMM | 486606106 | 1,518,851 | 147,033 | SH | DFND | 1 | 0 | 147,033 | 0 | |
FIDELITY INV MMTRSY 1 680 | COMM | X9USDFIDT | 317,014 | 317,014 | SH | DFND | 1 | 0 | 317,014 | 0 | |
ABEONA THERAPEUTICS INC | COMM | 00289Y206 | 2,645,853 | 624,022 | SH | DFND | 1 | 215,438 | 408,584 | 0 | |
ATHIRA PHARMA INC | COMM | 04746L104 | 3,955,899 | 1,492,792 | SH | DFND | 1 | 0 | 1,492,792 | 0 | |
PLAINS GP HOLDINGS LP-CL | COMM | 72651A207 | 25,827,815 | 1,372,360 | SH | DFND | 1 | 0 | 1,372,360 | 0 |