| Document and Entity Information | May 14, 2024 |
| Cover [Abstract] | |
| Amendment Flag | false |
| Entity Central Index Key | 0001971543 |
| Document Type | 8-K |
| Document Period End Date | May 14, 2024 |
| Entity Registrant Name | Mural Oncology plc |
| Entity Incorporation, State or Country Code | L2 |
| Entity File Number | 001-41837 |
| Entity Tax Identification Number | 98-1748617 |
| Entity Address, Address Line One | 10 Earlsfort Terrace |
| Entity Address, City or Town | Dublin 2 |
| Entity Address, Postal Zip Code | D02 T380 |
| Entity Address, Country | IE |
| City Area Code | 353 |
| Local Phone Number | 1-905-8020 |
| Written Communications | false |
| Soliciting Material | false |
| Pre-commencement Tender Offer | false |
| Pre-commencement Issuer Tender Offer | false |
| Title of 12(b) Security | Ordinary Shares, nominal value $0.01 |
| Trading Symbol | MURA |
| Security Exchange Name | NASDAQ |
| Entity Emerging Growth Company | true |
| Entity Ex Transition Period | false |
