Ambrx Biopharma, Inc.
10975 North Torrey Pines Road
La Jolla, CA 92037
November 1, 2023
VIA EDGAR
Securities and Exchange Commission
Division of Corporation Finance
Office of Life Sciences
100 F Street, N.E.
Washington, D.C. 20549
Attention: Joshua Gorsky
| Re: | Ambrx Biopharma, Inc. |
Registration Statement on Form S-3
File No. 333-275053
Ladies and Gentlemen:
Pursuant to Rule 461 under the Securities Act of 1933, as amended, Ambrx Biopharma, Inc. (the “Company”) hereby requests acceleration of the effective date of the above referenced Registration Statement to 5:30 p.m., Eastern Time, on November 2, 2023, or as soon thereafter as practicable, or at such other time as the Company or its outside counsel, Skadden, Arps, Slate, Meagher & Flom LLP, request by telephone that such Registration Statement be declared effective.
Please contact Gregg Noel, of Skadden, Arps, Slate, Meagher & Flom LLP, special counsel to the Company, at (650) 470-4540, as soon as the Registration Statement has been declared effective, or if you have any other questions or concerns regarding this matter.
| Sincerely, |
/s/ Daniel J. O’Connor |
| Daniel J. O’Connor |
| President and Chief Executive Officer |
