Segment Reporting - Sales from Products (Details) - USD ($) $ in Millions | 3 Months Ended | 6 Months Ended |
Jun. 30, 2024 | Jun. 30, 2023 | Jun. 30, 2024 | Jun. 30, 2023 |
Segment Reporting Information [Line Items] | | | | |
Sales | $ 16,112 | $ 15,035 | $ 31,887 | $ 29,522 |
Increase in hedge revenue | | | 118 | 128 |
Revenue related to the sale of the marketing rights | | | 76 | 54 |
U.S. | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 7,876 | 7,018 | 15,354 | 13,676 |
Non-US | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 8,236 | 8,018 | 16,533 | 15,846 |
Operating Segments | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 15,890 | 14,913 | 31,408 | 29,126 |
Operating Segments | U.S. | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 7,854 | 7,045 | 15,265 | 13,644 |
Operating Segments | Non-US | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 8,036 | 7,869 | 16,143 | 15,482 |
Corporate, Non-Segment | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 222 | 122 | 479 | 396 |
Corporate, Non-Segment | U.S. | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 22 | (27) | 89 | 32 |
Corporate, Non-Segment | Non-US | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 200 | 149 | 390 | 364 |
Pharmaceutical | Operating Segments | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 14,408 | 13,457 | 28,415 | 26,179 |
Pharmaceutical | Operating Segments | U.S. | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 7,399 | 6,570 | 14,336 | 12,688 |
Pharmaceutical | Operating Segments | Non-US | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 7,009 | 6,887 | 14,079 | 13,491 |
Pharmaceutical | Operating Segments | Keytruda | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 7,270 | 6,271 | 14,217 | 12,065 |
Pharmaceutical | Operating Segments | Keytruda | U.S. | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 4,412 | 3,863 | 8,531 | 7,348 |
Pharmaceutical | Operating Segments | Keytruda | Non-US | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 2,858 | 2,408 | 5,686 | 4,718 |
Pharmaceutical | Operating Segments | Alliance revenue - Lynparza | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 317 | 310 | 609 | 585 |
Pharmaceutical | Operating Segments | Alliance revenue - Lynparza | U.S. | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 153 | 144 | 288 | 286 |
Pharmaceutical | Operating Segments | Alliance revenue - Lynparza | Non-US | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 165 | 166 | 321 | 299 |
Pharmaceutical | Operating Segments | Alliance revenue - Lenvima | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 249 | 242 | 504 | 474 |
Pharmaceutical | Operating Segments | Alliance revenue - Lenvima | U.S. | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 177 | 163 | 349 | 316 |
Pharmaceutical | Operating Segments | Alliance revenue - Lenvima | Non-US | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 73 | 79 | 155 | 158 |
Pharmaceutical | Operating Segments | Welireg | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 126 | 50 | 211 | 92 |
Pharmaceutical | Operating Segments | Welireg | U.S. | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 116 | 49 | 194 | 90 |
Pharmaceutical | Operating Segments | Welireg | Non-US | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 10 | 2 | 17 | 3 |
Pharmaceutical | Operating Segments | Alliance Revenue - Reblozyl | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 90 | 47 | 161 | 90 |
Pharmaceutical | Operating Segments | Alliance Revenue - Reblozyl | U.S. | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 75 | 36 | 133 | 66 |
Pharmaceutical | Operating Segments | Alliance Revenue - Reblozyl | Non-US | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 15 | 11 | 28 | 24 |
Pharmaceutical | Operating Segments | Gardasil/Gardasil 9 | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 2,478 | 2,458 | 4,727 | 4,430 |
Pharmaceutical | Operating Segments | Gardasil/Gardasil 9 | U.S. | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 536 | 464 | 1,024 | 880 |
Pharmaceutical | Operating Segments | Gardasil/Gardasil 9 | Non-US | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 1,941 | 1,994 | 3,702 | 3,550 |
Pharmaceutical | Operating Segments | ProQuad/M-M-R II/Varivax | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 617 | 582 | 1,187 | 1,109 |
Pharmaceutical | Operating Segments | ProQuad/M-M-R II/Varivax | U.S. | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 490 | 447 | 928 | 868 |
Pharmaceutical | Operating Segments | ProQuad/M-M-R II/Varivax | Non-US | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 127 | 135 | 259 | 242 |
Pharmaceutical | Operating Segments | Vaxneuvance | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 189 | 168 | 408 | 274 |
Pharmaceutical | Operating Segments | Vaxneuvance | U.S. | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 99 | 147 | 260 | 241 |
Pharmaceutical | Operating Segments | Vaxneuvance | Non-US | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 90 | 20 | 148 | 33 |
Pharmaceutical | Operating Segments | RotaTeq | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 163 | 131 | 379 | 428 |
Pharmaceutical | Operating Segments | RotaTeq | U.S. | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 107 | 93 | 257 | 273 |
Pharmaceutical | Operating Segments | RotaTeq | Non-US | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 56 | 37 | 123 | 155 |
Pharmaceutical | Operating Segments | Pneumovax 23 | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 59 | 92 | 120 | 188 |
Pharmaceutical | Operating Segments | Pneumovax 23 | U.S. | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 11 | 23 | 17 | 63 |
Pharmaceutical | Operating Segments | Pneumovax 23 | Non-US | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 48 | 69 | 103 | 125 |
Pharmaceutical | Operating Segments | Bridion | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 455 | 502 | 895 | 989 |
Pharmaceutical | Operating Segments | Bridion | U.S. | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 351 | 299 | 680 | 576 |
Pharmaceutical | Operating Segments | Bridion | Non-US | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 104 | 203 | 215 | 413 |
Pharmaceutical | Operating Segments | Prevymis | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 188 | 143 | 362 | 273 |
Pharmaceutical | Operating Segments | Prevymis | U.S. | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 90 | 61 | 165 | 116 |
Pharmaceutical | Operating Segments | Prevymis | Non-US | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 98 | 82 | 197 | 157 |
Pharmaceutical | Operating Segments | Dificid | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 92 | 76 | 165 | 141 |
Pharmaceutical | Operating Segments | Dificid | U.S. | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 79 | 68 | 147 | 130 |
Pharmaceutical | Operating Segments | Dificid | Non-US | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 12 | 8 | 17 | 11 |
Pharmaceutical | Operating Segments | Zerbaxa | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 62 | 54 | 118 | 104 |
Pharmaceutical | Operating Segments | Zerbaxa | U.S. | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 33 | 30 | 67 | 57 |
Pharmaceutical | Operating Segments | Zerbaxa | Non-US | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 28 | 24 | 51 | 47 |
Pharmaceutical | Operating Segments | Noxafil | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 45 | 55 | 101 | 116 |
Pharmaceutical | Operating Segments | Noxafil | U.S. | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 0 | 11 | 8 | 25 |
Pharmaceutical | Operating Segments | Noxafil | Non-US | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 44 | 45 | 92 | 91 |
Pharmaceutical | Operating Segments | Alliance revenue - Adempas/Verquvo | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 106 | 68 | 203 | 167 |
Pharmaceutical | Operating Segments | Alliance revenue - Adempas/Verquvo | U.S. | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 98 | 70 | 188 | 153 |
Pharmaceutical | Operating Segments | Alliance revenue - Adempas/Verquvo | Non-US | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 8 | (2) | 16 | 14 |
Pharmaceutical | Operating Segments | Adempas | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 72 | 65 | 142 | 125 |
Pharmaceutical | Operating Segments | Adempas | U.S. | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 0 | 0 | 0 | 0 |
Pharmaceutical | Operating Segments | Adempas | Non-US | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 72 | 65 | 142 | 125 |
Pharmaceutical | Operating Segments | Winrevair | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 70 | 0 | 70 | 0 |
Pharmaceutical | Operating Segments | Winrevair | U.S. | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 70 | 0 | 70 | 0 |
Pharmaceutical | Operating Segments | Winrevair | Non-US | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 0 | 0 | 0 | 0 |
Pharmaceutical | Operating Segments | Lagevrio | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 110 | 203 | 460 | 595 |
Pharmaceutical | Operating Segments | Lagevrio | U.S. | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 15 | 2 | 60 | 0 |
Pharmaceutical | Operating Segments | Lagevrio | Non-US | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 95 | 201 | 400 | 595 |
Pharmaceutical | Operating Segments | Isentress/Isentress HD | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 89 | 136 | 200 | 259 |
Pharmaceutical | Operating Segments | Isentress/Isentress HD | U.S. | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 43 | 56 | 93 | 108 |
Pharmaceutical | Operating Segments | Isentress/Isentress HD | Non-US | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 46 | 80 | 107 | 151 |
Pharmaceutical | Operating Segments | Delstrigo | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 60 | 50 | 116 | 94 |
Pharmaceutical | Operating Segments | Delstrigo | U.S. | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 14 | 13 | 26 | 24 |
Pharmaceutical | Operating Segments | Delstrigo | Non-US | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 45 | 37 | 89 | 70 |
Pharmaceutical | Operating Segments | Pifeltro | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 39 | 38 | 81 | 72 |
Pharmaceutical | Operating Segments | Pifeltro | U.S. | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 27 | 27 | 56 | 51 |
Pharmaceutical | Operating Segments | Pifeltro | Non-US | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 12 | 11 | 25 | 21 |
Pharmaceutical | Operating Segments | Belsomra | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 53 | 63 | 99 | 119 |
Pharmaceutical | Operating Segments | Belsomra | U.S. | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 19 | 21 | 33 | 37 |
Pharmaceutical | Operating Segments | Belsomra | Non-US | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 34 | 42 | 66 | 82 |
Pharmaceutical | Operating Segments | Simponi | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 172 | 180 | 356 | 359 |
Pharmaceutical | Operating Segments | Simponi | U.S. | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 0 | 0 | 0 | 0 |
Pharmaceutical | Operating Segments | Simponi | Non-US | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 172 | 180 | 356 | 359 |
Pharmaceutical | Operating Segments | Remicade | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 35 | 48 | 74 | 99 |
Pharmaceutical | Operating Segments | Remicade | U.S. | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 0 | 0 | 0 | 0 |
Pharmaceutical | Operating Segments | Remicade | Non-US | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 35 | 48 | 74 | 99 |
Pharmaceutical | Operating Segments | Januvia | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 405 | 511 | 824 | 1,062 |
Pharmaceutical | Operating Segments | Januvia | U.S. | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 177 | 243 | 361 | 514 |
Pharmaceutical | Operating Segments | Januvia | Non-US | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 227 | 267 | 463 | 548 |
Pharmaceutical | Operating Segments | Janumet | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 224 | 354 | 475 | 683 |
Pharmaceutical | Operating Segments | Janumet | U.S. | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 17 | 82 | 55 | 138 |
Pharmaceutical | Operating Segments | Janumet | Non-US | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 208 | 272 | 420 | 544 |
Pharmaceutical | Operating Segments | Other pharmaceutical | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 573 | 560 | 1,151 | 1,187 |
Pharmaceutical | Operating Segments | Other pharmaceutical | U.S. | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 190 | 158 | 346 | 328 |
Pharmaceutical | Operating Segments | Other pharmaceutical | Non-US | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 386 | 403 | 807 | 857 |
Animal Health | Operating Segments | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 1,482 | 1,456 | 2,993 | 2,947 |
Animal Health | Operating Segments | U.S. | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 455 | 475 | 929 | 956 |
Animal Health | Operating Segments | Non-US | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 1,027 | 982 | 2,064 | 1,991 |
Animal Health | Operating Segments | Livestock | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 837 | 807 | 1,686 | 1,656 |
Animal Health | Operating Segments | Livestock | U.S. | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 168 | 165 | 334 | 338 |
Animal Health | Operating Segments | Livestock | Non-US | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 669 | 643 | 1,352 | 1,318 |
Animal Health | Operating Segments | Companion Animal | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 645 | 649 | 1,307 | 1,291 |
Animal Health | Operating Segments | Companion Animal | U.S. | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | 287 | 310 | 595 | 618 |
Animal Health | Operating Segments | Companion Animal | Non-US | | | | |
Segment Reporting Information [Line Items] | | | | |
Sales | $ 358 | $ 339 | $ 712 | $ 673 |