Provectus Biopharmaceuticals (PVCT) 10-Q 2008 Q3 Quarterly report

Exhibit 32.1

Provectus Pharmaceuticals, Inc.

Certification Pursuant to 18 U.S.C. ss. 1350

Section 906 Certifications

Pursuant  to 18  U.S.C.  ss.  1350,  as  enacted  by  Section  906  of  the Sarbanes-Oxley Act of 2002 (Public Law 107-204), the undersigned, H. Craig Dees, Ph.D., the Chief Executive Officer of Provectus Pharmaceuticals,  Inc., a Nevada corporation (the "Company"), and Peter R. Culpepper, the Chief Financial Officer of the Company, hereby certify that:

1.   The Company's Quarterly Report on Form 10-Q for the quarter ended September 30, 2008, as filed with the U.S.  Securities and Exchange Commission on the date hereof (the "Report"), fully complies with the requirements of Section 13(a) or 15(d) of the Securities Exchange Act of 1934; and

2.   The information contained in the Report fairly presents, in all material respects, the financial condition and results of operations of the Company.

This Certification is signed on November 14, 2008.

/s/ H. Craig Dees	/s/ Peter R. Culpepper
Name:  H. Craig Dees, Ph.D.	Name:  Peter R. Culpepper
Title:  Chief Executive Officer	Title:  Chief Financial Officer

A signed original of this written statement required by Section 906 has been provided to Provectus Pharmaceuticals, Inc. and will be retained by Provectus Pharmaceuticals, Inc. and furnished to the Securities and Exchange Commission or its staff upon request.