Enzo Biochem (ENZ) DEFA14A Additional proxy soliciting materials

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

WASHINGTON, DC 20549

SCHEDULE 14A

Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

Filed by the Registrant x

Filed by a Party other than the Registrant o

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o Preliminary Proxy Statement

o Confidential, For Use of the Commission Only (as permitted by Rule 14a-6(e)(2))

o Definitive Proxy Statement

x Definitive Additional Materials

o Soliciting Material Under Rule 14a-12

Enzo Biochem, Inc.

(Name of Registrant as Specified in Its Charter)

(Name of Person(s) Filing Proxy Statement, if Other Than the Registrant)

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*** Exercise YourRight to Vote ***
Important Notice Regarding the Availability of Proxy Materials for the
Shareholder Meeting to Be Held on January 26, 2012

ENZO BIOCHEM, INC.	Meeting Information
	Meeting Type:Annual Meeting
	For holders as of:		December 2, 2011
	Date:  January 26, 2012         Time:  9:00 AM EST
ENZO BIOCHEM, INC. 60 EXECUTIVE BLVD. FARMINGDALE, NY 11735	Location:	Yale Club 50 Vanderbilt Avenue New York, NY 10017
	You are receiving this communication because you hold shares in the above named company. This is not a ballot. You cannot use this notice to vote these shares. This communication presents only an overview of the more complete proxy materials that are available to you on the Internet. You may view the proxy materials online atwww.proxyvote.com or easily request a paper copy (see reverse side). We encourage you to access and review all of the important information contained in the proxy materials before voting.
	See the reverse side of this notice to obtain proxy materials and voting instructions.

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	Before You Vote
How to Access the Proxy Materials

Proxy Materials Available to VIEW or RECEIVE:
1. Notice & Proxy Statement       2. Form 10-K
How to View Online:
Have the information that is printed in the box marked by the arrow					XXXX XXXX XXXX	(located on the following page) and visit:www.proxyvote.com.
How to Request and Receive a PAPER or E-MAIL Copy:
If you want to receive a paper or e-mail copy of these documents, you must request one. There is NO charge for requesting a copy. Please choose one of the following methods to make your request:
		1)	BY INTERNET:	www.proxyvote.com
		2)	BY TELEPHONE:	1-800-579-1639
		3)	BY E-MAIL*:	sendmaterial@proxyvote.com
*	If   requesting  materials  by  e-mail, please  send a  blank  e-mail with  the  information  that  is  printed in the box marked  by the  arrow						XXXX XXXX XXXX	(located  on  the
following page) in the subject line.
Requests, instructions and other inquiries sent to this e-mail address will NOT be forwarded to your investment advisor. Please make the request as instructed above on or before January 01, 2012 to facilitate timely delivery.

	How To Vote
Please Choose One of the Following Voting Methods

Vote In Person: Many shareholder meetings have attendance requirements including, but not limited to, the possession of an attendance ticket issued by the entity holding the meeting. Please check the meeting materials for any special requirements for meeting attendance. At the meeting, you will need to request a ballot to vote these shares.
Vote  By  Internet: To vote now  by  Internet, go to  www.proxyvote.com.  Have  the  information  that  is  printed in  the  box  marked by the arrow	XXXX XXXX XXXX	available  and
follow the instructions.
Vote By Mail: You can vote by mail by requesting a paper copy of the materials, which will include a proxy card.

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Voting items

The Board of Directors recommends you vote
FOR the following:

1.	Election of Directors
	Nominees
01	Dr. Elazar Rabbani

The Board of Directors recommends you vote FOR the following proposal:
2	To approve, in a nonbinding advisory vote, the compensation of the Company’s named executive officers.
The Board of Directors recommends you vote 3 YEARS on the following proposal:
3	To determine, in a nonbinding advisory vote, whether a stockholder vote to approve the compensation of the Company’s named executive officers should occur every one, two, or three years.
The Board of Directors recommends you vote FOR the following proposal:
4	To ratify the appointment of Ernst & Young LLP as the Company’s independent registered public accounting firm for the Company’s fiscal year ending July 31, 2012.
NOTE: In their discretion, the Proxies are authorized to vote upon such other business as may properly come before the Annual Meeting. This proxy when properly executed will be voted in the manner directed herein by the undersigned shareholder. If no direction is made, this proxy will be voted FOR the election of the nominee for Class III Director named in Proposal 1 in this proxy card, FOR each of Proposals 2 and 4, and 3 YEARS for Proposal 3 in this proxy card.

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