OG&A expenses, as a percentage of sales, were 16.34% in the third quarter of 2022 and 16.25% in the third quarter of 2021. The increase in the third quarter of 2022, compared to the third quarter of 2021, resulted primarily from investments in our associates, increased incentive plan costs, costs related to strategic investments in various margin expansion initiatives that will drive future growth and the 2022 Third Quarter OG&A Adjusted Items, partially offset by the effect of sales leverage across fuel and supermarkets, which decreases our OG&A rate, as a percentage of sales, decreased healthcare costs, the 2021 Third Quarter OG&A Adjusted Items and broad-based improvement from cost savings initiatives that drive administrative efficiencies, store productivity and sourcing cost reductions.
OG&A expenses, as a percentage of sales, were 15.87% in the first three quarters of 2022 and 16.88% in the first three quarters of 2021. The decrease in the first three quarters of 2022, compared to the first three quarters of 2021, resulted primarily from the effect of sales leverage across fuel and supermarkets, which decreases our OG&A rate, as a percentage of sales, lower contributions to multi-employer pension plans, decreased healthcare costs, the 2021 OG&A Adjusted Items and broad-based improvement from cost savings initiatives that drive administrative efficiencies, store productivity and sourcing cost reductions, partially offset by investments in our associates, costs related to strategic investments in various margin expansion initiatives that will drive future growth and the 2022 OG&A Adjusted Items.
Our fuel sales lower our OG&A rate, as a percentage of sales, due to the very low OG&A rate, as a percentage of sales, of fuel sales compared to non-fuel sales. Excluding the effect of fuel, the 2022 Third Quarter OG&A Adjusted Items and the 2021 Third Quarter OG&A Adjusted Items, our OG&A rate decreased 3 basis points in the third quarter of 2022, compared to the third quarter of 2021. This decrease resulted primarily from the effect of supermarket sales leverage, which decreases our OG&A rate, as a percentage of sales, decreased healthcare costs and broad-based improvement from cost savings initiatives that drive administrative efficiencies, store productivity and sourcing cost reductions, partially offset by investments in our associates, increased incentive plan costs and costs related to strategic investments in various margin expansion initiatives that will drive future growth.
Excluding the effect of fuel, the 2022 OG&A Adjusted Items and the 2021 OG&A Adjusted Items, our OG&A rate decreased 8 basis points in the first three quarters of 2022, compared to the first three quarters of 2021. This decrease resulted primarily from the effect of supermarket sales leverage, which decreases our OG&A rate, as a percentage of sales, lower contributions to multi-employer pension plans, decreased healthcare costs and broad-based improvement from cost savings initiatives that drive administrative efficiencies, store productivity and sourcing cost reductions, partially offset by investments in our associates and costs related to strategic investments in various margin expansion initiatives that will drive future growth.
Rent Expense
Rent expense decreased, as a percentage of sales, for the third quarter of 2022, compared to the third quarter of 2021, primarily due to sales leverage. Rent expense decreased in total and as a percentage of sales for the first three quarters of 2022, compared to the first three quarters of 2021. This decrease was primarily due to sales leverage and the completion of a property transaction during the first quarter of 2021 related to 28 previously leased properties that we are now accounting for as owned locations and therefore recognizing depreciation and amortization expense over their useful life.
Depreciation and Amortization Expense
Depreciation and amortization expense decreased, as a percentage of sales, in the third quarter and first three quarters of 2022, compared to the same periods in 2021, primarily due to sales leverage.
Operating Profit and FIFO Operating Profit
Operating profit was $841 million, or 2.5% of sales, for the third quarter of 2022, compared to $868 million, or 2.7% of sales, for the third quarter of 2021. Operating profit, as a percentage of sales, decreased 26 basis points in the third quarter of 2022, compared to the third quarter of 2021, due to an increased LIFO charge, a lower FIFO gross margin rate and increased OG&A expense, as a percentage of sales. Fuel earnings contributed to our operating profit growth for the third quarter of 2022, compared to the third quarter of 2021.