Other income (expense), net, increased by $172,621 from $325,067 in 2005 to $497,688 in 2006. The majority of the increase is from increased interest income from higher interest rates and the effect of foreign exchange. Interest income increased by $101,106, or 28%, to $458,626 in 2006 from $357,520 in 2005 as a result of higher interest rates. The gain related to the valuation of warrants decreased by $4,129 to $7,624 in 2006 from $11,753 in 2005. During the quarter, the Company recorded in other income royalties of $657 compared with $8,289 in 2005 per the licensing agreement with Herbamed Ltd, a company controlled by Dr. Haim Aviv, the Company’s CEO. Six Months ended June 30, 2006 and 2005 Total operating expenses for the first half of 2006 increased marginally by $3,956 from $8,058,204 in 2005 to $8,054,248 in 2006. The Company has entered Phase II testing in pain indications with cannabinor in the second quarter of 2006. The Company’s NanoEmulsion drug delivery system is in clinical stage development for the topical application of analgesic and anti-inflammatory agents. The Company expects to commence a clinical program in the third quarter of 2006 for its NanoEmulsion drug delivery system. During the first half of 2006, the Company incurred higher compensation costs of approximately $1.2 million related to severance costs for the departure of a number of executives and the 2006 implementation of the equity based compensation of SFAS 123(R) and higher costs of $0.5 million incurred for the Company’s forthcoming shareholder meeting including an ongoing proxy contest which were offset by lower costs for clinical studies, lower litigation costs for the class action suits and lower salaries related to a reduction in workforce, as compared with the first half of 2005. Research efforts in the first half of 2006 have been focused on the completion of cannabinor toxicology, scale-up manufacturing, technology transfer to the active ingredient supplier, and clinical trial finished material at Pharmos’ facility in Rehovot, Israel, as well as continuing to identify new, potentially more potent, CB2 agonists. The Company considers major research & development projects to be those projects that have reached at least Phase II level of clinical development. At this time, there are no projects that are in Phase II. Cannabinor is in Phase II at the end of the second quarter. During the first half of 2006, the gross cost of development and review was approximately $0.7 million. Total costs since the cannabinor project entered Phase II development in 2006 through June 30, 2006 were $0.7 million, Gross expenses for other research and development projects in early stages of development for the first half of 2006 and 2005 were $1,531,316 and $904,820, respectively. Research & development (R&D) gross expenses decreased by $796,148 or 16% from $5,045,236 in 2005 to $4,249,088 in 2006, related to a reduction in clinical activities. Costs associated with clinical activities have started to be incurred late in the second quarter. The Company recorded research and development grant receivables from the Office of the Chief Scientist of Israel’s Ministry of Industry and Trade of $668,261 and $731,455 during the first half of 2006 and 2005, respectively, which reduced research and development expenses. Total research and development expenses, net of grants, decreased by $732,954 or 17% from $4,313,781 in 2005 to $3,580,827 in 2006. General and administrative expenses for the six months ended June 30, 2006 increased by $777,797, or 22%, from $3,530,746 in 2005 to $4,308,543 in total. These figures contain expenses which total $1,365,439 costs for the Company’s forthcoming shareholder meeting including an ongoing proxy contest and severance costs for some executives. Excluding this $1,365,439 in costs, general and administrative costs would have decreased by $587,642 or 17% from $3,530,746 in 2005 to $2,943,104. Excluding these costs mentioned above, decreases vs. 2005 were realized in professional fees in the amount of $422,365 from reduced litigation costs from the class action suites from meeting the insurance deductible, and a net decrease in compensation of $137,795 as a result of lower salaries related to the reduction in workforce in 2005 and the reduced amortization costs related to the 50% share of the Retention Awards which vested on December 31, 2005 offset by the cost of implementation of the equity based compensation related to the 2006 implementation of SFAS 123(R). Depreciation and amortization expenses decreased by $48,799, or 23%, from $213,677 in 2005 to $164,878 in 2006. The decrease is due to fixed assets which have become fully depreciated. |