| Cover | Apr. 21, 2021 |
| Cover [Abstract] | |
| Document Type | 8-K |
| Amendment Flag | false |
| Document Period End Date | Apr. 21, 2021 |
| Entity File Number | 000-13789 |
| Entity Registrant Name | Adhera Therapeutics, Inc. |
| Entity Central Index Key | 0000737207 |
| Entity Tax Identification Number | 11-2658569 |
| Entity Incorporation, State or Country Code | DE |
| Entity Address, Address Line One | 8000 Innovation Parkway |
| Entity Address, City or Town | Baton Rouge |
| Entity Address, State or Province | LA |
| Entity Address, Postal Zip Code | 70820 |
| City Area Code | 919 |
| Local Phone Number | 518-3748 |
| Written Communications | false |
| Soliciting Material | false |
| Pre-commencement Tender Offer | false |
| Pre-commencement Issuer Tender Offer | false |
| Entity Emerging Growth Company | false |
