Exhibit 16.1
January 30, 2025
Securities and Exchange Commission
100 F Street, N.E.
Washington, DC 20549
Commissioners:
We have read the statements made by Applied DNA Sciences, Inc. under Item 4.01 of its Form 8-K dated January 30, 2025. We agree with the statements concerning our Firm in such Form 8-K; we are not in a position to agree or disagree with other statements of Applied DNA Sciences, Inc. contained therein.
Very truly yours,
/s/ Marcum LLP
Marcum LLP
