Knott David M 13F-HR Quarterly holdings report by institutional manager

The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE

OMB APPROVAL

OMB Number:		3235-0006
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COLUMN 1	COLUMN 2	COLUMN 3	COLUMN 4	COLUMN 5			COLUMN 6	COLUMN 7	COLUMN 8
			VALUE	SHRS OR	SH/	PUT/	INVESTMENT	OTHER	VOTING AUTHORITY
NAME OF ISSUER	TITLE OF CLASS	CUSIP	(x$1000)	PRN AMT	PRN	CALL	DISCRETION	MANAGER	SOLE	SHARED	NONE
AbbVie Inc.	Common	00287Y109	2,117	27,953	SH		DFND	2	27,953	0	0
AbbVie Inc.	Common	00287Y109	379	5,000	SH		DFND	1	0	5,000	0
Acceleron Pharma, Inc.	Common	00434H108	859	21,749	SH		DFND	2	21,749	0	0
Aimmune Therapeutics, Inc.	Common	00900T107	1,173	55,990	SH		DFND	2	55,990	0	0
Alcon, Inc	Common	H01301128	35	600	SH		DFND	2	600	0	0
Alimera Sciences, Inc.	Common	016259103	259	458,120	SH		DFND	2	458,120	0	0
AllianceBernstein Holdings PL Unit Ltd	Common	01881G106	1,438	49,000	SH		DFND	1	0	49,000	0
AllianceBernstein Holdings PL Unit Ltd	Common	01881G106	44	1,500	SH		DFND	1	1,500	0	0
Alerian MLP	Common	00162Q866	5	600	SH		DFND	1	0	600	0
Alphabet Inc-Cl C	Common	02079K107	9,630	7,900	SH		DFND	2	7,900	0	0
American Outdoor Brands Corporation	Common	02874P103	2,282	390,000	SH		DFND	2	390,000	0	0
Apollo Global Management, Inc.	Common	03768E105	12,205	322,708	SH		DFND	2	322,708	0	0
Apple Inc.	Common	037833100	118	525	SH		DFND	1	0	525	0
Apple Inc.	Common	037833100	118	525	SH		DFND	1	525	0	0
Arena Pharmaceuticals, Inc.	Common	040047607	659	14,391	SH		DFND	2	14,391	0	0
Ascendis Pharma A/S	Common	04351P901	63	656	SH		DFND	2	656	0	0
AT&T Inc.	Common	00206R102	757	20,000	SH		DFND	1	0	20,000	0
AT&T Inc.	Common	00206R102	78	2,050	SH		DFND	1	2,050	0	0
Aurinia Pharmaceuticals Inc.	Common	05156V102	283	53,000	SH		DFND	2	53,000	0	0
Bank Nova Scotia Halifax	Common	064149107	23	400	SH		DFND	1	0	400	0
Bellicum Pharmaceuticals	Common	079481107	177	168,203	SH		DFND	2	168,203	0	0
Bellicum Pharmaceuticals @ 5 exp 11/19	Common	9EDW5GYA8	1	100	SH		DFND	2	100	0	0
Bellus Health Inc.	Common	07987C204	1,559	242,611	SH		DFND	2	242,611	0	0
BioDelivery Sciences International, Inc.	Common	09060J106	2,179	517,507	SH		DFND	2	517,507	0	0
Bristol-Myers Squibb Company	Common	110122108	1,515	29,868	SH		DFND	2	29,868	0	0
Calumet Specialty Products Partners, LP	Common	131476103	7,280	2,000,000	SH		DFND	2	2,000,000	0	0
Calumet Specialty Products Partners, LP	Common	131476103	73	20,000	SH		DFND	1	20,000	0	0
Canadian Natural Resources Inc.	Common	136385101	366	13,750	SH		DFND	1	0	13,750	0
Canadian Natural Resources Inc.	Common	136385101	487	18,285	SH		DFND	1	18,600	0	0
Capitol Federal Financial Inc.	Common	14057J101	55	4,000	SH		DFND	1	0	4,000	0
Capitol Federal Financial Inc.	Common	14057J101	80	5,800	SH		DFND	1	5,800	0	0
Catalyst Pharmaceuticals, Inc.	Common	14888U101	804	151,415	SH		DFND	2	151,415	0	0
Celgene Corporation	Common	151020104	1,574	15,847	SH		DFND	2	15,847	0	0
Centerstate Banks Corp	Common	15201P109	43	1,780	SH		DFND	1	0	1,780	0
Centerstate Banks Corp	Common	15201P109	124	5,162	SH		DFND	1	5,162	0	0
Check Cap Ltd.	Common	M2361E203	4	2,224	SH		DFND	2	2,224	0	0
Check Cap Ltd. @7.50 Exp. 2/28/20	Common	M2361E120	482	64,309	SH		DFND	2	64,309	0	0
Chemours Co.	Common	163851108	7	440	SH		DFND	1	0	440	0
Chemours Co.	Common	163851108	11	720	SH		DFND	1	720	0	0
ChemoCentryx, Inc	Common	16383L106	34	5,000	SH		DFND	2	5,000	0	0
Cidara Therapeutics, Inc.	Common	171757107	390	195,666	SH		DFND	2	195,666	0	0
Coherus Biosciences, Inc.	Common	19249H103	1,284	63,387	SH		DFND	2	63,387	0	0
Coca Cola	Common	191216100	414	7,600	SH		DFND	1	0	7,600	0
Coca Cola	Common	191216100	316	5,800	SH		DFND	1	5,800	0	0
Colony Northstar Inc.	Common	19625W104	9	1,466	SH		DFND	1	0	1,466	0
Columbia Financial, Inc.	Common	197641103	369	23,363	SH		DFND	2	23,363	0	0
Community Healthcare Trust Incorporated	Common	20369C106	2,673	60,000	SH		DFND	2	60,000	0	0
Conagra Brands	Common	205887102	307	10,000	SH		DFND	1	0	10,000	0
Corteva Inc.	Common	22052L104	309	11,051	SH		DFND	1	0	11,051	0
Corteva Inc.	Common	22052L104	42	1,494	SH		DFND	1	1,494	0	0
Cousins Properties	Common	222795106	126	3,357	SH		DFND	1	0	3,357	0
CymaBay Therapeutics, Inc.	Common	23257D103	413	80,889	SH		DFND	2	80,889	0	0
Dell Technologies Inc.	Common	24703L202	333	6,426	SH		DFND	2	6,426	0	0
Delta Air Lines, Inc.	Common	247361702	3,312	57,500	SH		DFND	2	57,500	0	0
Dow Inc.	Common	260557103	527	11,051	SH		DFND	1	0	11,051	0
Dow Inc.	Common	260557103	71	1,494	SH		DFND	1	1,494	0	0
Dupont DE Nemours Inc.	Common	26614N102	788	11,051	SH		DFND	1	0	11,051	0
Dupont DE Nemours Inc.	Common	26614N102	107	1,494	SH		DFND	1	1,494	0	0
Eagle Materials Inc.	Common	26969P108	21	228	SH		DFND	1	0	228	0
Eiger BioPharmaceuticals, Inc.	Common	28249U105	2,403	234,448	SH		DFND	2	234,448	0	0
Eli Lilly Inc.	Common	532457108	34	300	SH		DFND	1	0	300	0
Entegra Financial Corporation	Common	29363J108	90	3,000	SH		DFND	1	0	3,000	0
Entegra Financial Corporation	Common	29363J108	218	7,250	SH		DFND	1	7,250	0	0
Essential Properties Realty Trust, Inc.	Common	29670E107	1,833	80,000	SH		DFND	2	80,000	0	0
Fannie Mae 4.75 percent Series M	Common	313586836	978	43,000	SH		DFND	2	43,000	0	0
Fannie Mae 5.1 percent Series E	Common	313586604	11	500	SH		DFND	2	500	0	0
Fannie Mae 5.125 percent Series L	Common	313586844	193	8,680	SH		DFND	2	8,680	0	0
Fannie Mae 5.81 percent Series H	Common	313586885	228	10,000	SH		DFND	2	10,000	0	0
Fannie Mae 8.25 percent Series S	Common	313586752	801	60,000	SH		DFND	2	60,000	0	0
Fannie Mae 8.25 percent Series T	Common	313586737	3,043	234,236	SH		DFND	2	234,236	0	0
Fannie Mae Float Series P	Common	313586786	599	49,720	SH		DFND	2	49,720	0	0
FNB Corporation	Common	302520101	103	8,905	SH		DFND	1	0	8,905	0
Foamix Pharmaceuticals Ltd.	Common	M46135105	1,128	371,146	SH		DFND	2	371,146	0	0
Fortress Trans & Infrastructure Inv. LLC	Common	34960P101	13,461	888,509	SH		DFND	2	888,509	0	0
Freddie Mac 5 percent Series F	Common	313400863	473	21,590	SH		DFND	2	21,590	0	0
Freddie Mac 5.3 percent	Common	313400822	2,135	100,000	SH		DFND	2	100,000	0	0
Freddie Mac 5.57 percent Series V	Common	313400673	445	39,739	SH		DFND	2	39,739	0	0
Freddie Mac 6 percent Series P	Common	313400749	116	5,200	SH		DFND	2	5,200	0	0
Freddie Mac 6.02 percent Series X	Common	313400657	651	53,811	SH		DFND	2	53,811	0	0
Freddie Mac 8.375 percent Series Z	Common	313400624	1,826	139,500	SH		DFND	2	139,500	0	0
FS Bancorp Inc.	Common	30263Y104	77	1,460	SH		DFND	1	0	1,460	0
FS Bancorp Inc.	Common	30263Y104	111	2,117	SH		DFND	1	2,117	0	0
FS KKR Capital Corp.	Common	302635107	8,162	1,400,000	SH		DFND	2	1,400,000	0	0
FS KKR Capital Corp.	Common	302635107	612	105,000	SH		DFND	1	0	105,000	0
FS KKR Capital Corp.	Common	302635107	128	22,000	SH		DFND	1	22,000	0	0
General Electric	Common	369604103	11	1,200	SH		DFND	1	0	1,200	0
General Electric	Common	369604103	31	3,480	SH		DFND	1	3,480	0	0
Global Medical REIT, Inc. Ser A Cum Pfd.	Common	37957W203	930	35,000	SH		DFND	2	35,000	0	0
Globus Medical, Inc.	Common	379577208	148	2,900	SH		DFND	2	2,900	0	0
Heritage NOLA Bancorp Inc.	Common	42727P108	38	3,000	SH		DFND	1	0	3,000	0
Heritage NOLA Bancorp Inc.	Common	42727P108	114	9,000	SH		DFND	1	9,000	0	0
Horizon Therapeutics Public Ltd. Company	Common	G46188101	1,753	64,364	SH		DFND	2	64,364	0	0
International Business Machines	Common	459200101	623	4,284	SH		DFND	1	0	4,284	0
International Gaming Technologies	Common	G4863A108	107	7,500	SH		DFND	1	0	7,500	0
International Gaming Technologies	Common	G4863A108	8,526	600,000	SH		DFND	2	600,000	0	0
Johnson & Johnson	Common	478160104	285	2,200	SH		DFND	1	0	2,200	0
Johnson & Johnson	Common	478160104	657	5,080	SH		DFND	1	5,080	0	0
JP Morgan Chase	Common	46625H100	1,036	8,800	SH		DFND	1	0	8,800	0
JP Morgan Chase	Common	46625H100	1,677	14,250	SH		DFND	1	14,250	0	0
Kadmon Holdings, Inc.	Common	48283N106	264	104,700	SH		DFND	2	104,700	0	0
Kimberly Clark Corporation	Common	494368103	852	6,000	SH		DFND	1	0	6,000	0
Krystal Biotech, Inc.	Common	501147102	201	5,797	SH		DFND	2	5,797	0	0
Legacy Housing Corporation	Common	52472M101	65	4,000	SH		DFND	1	0	4,000	0
Legacy Housing Corporation	Common	52472M101	81	5,000	SH		DFND	1	5,000	0	0
Lexicon Pharmaceuticals, Inc.	Common	528872302	90	29,800	SH		DFND	2	29,800	0	0
Ligand Pharmaceuticals Incorporated	Common	53220K504	34,062	342,198	SH		DFND	2	342,198	0	0
Ligand Pharmaceuticals Incorporated	Common	53220K504	183	1,843	SH		DFND	1	0	1,843	0
Ligand Pharmaceuticals Incorporated	Common	53220K504	896	9,000	SH		DFND	1	9,000	0	0
LKQ Corporation	Common	501889208	9,435	300,000	SH		DFND	2	300,000	0	0
Macquarie Infrastructure Corporation	Common	55608B105	6,457	163,600	SH		DFND	2	163,600	0	0
Macquarie Infrastructure Corporation	Common	55608B105	355	9,000	SH		DFND	1	0	9,000	0
Macquarie Infrastructure Corporation	Common	55608B105	130	3,300	SH		DFND	1	3,300	0	0
Medtronics Inc.	Common	G5960L103	114	1,050	SH		DFND	1	0	1,050	0
MEI Pharma, Inc.	Common	55279B202	65	38,590	SH		DFND	2	38,590	0	0
Merck & Co. Inc.	Common	58993Y105	42	500	SH		DFND	1	0	500	0
Merck & Co. Inc.	Common	58993Y105	67	800	SH		DFND	1	800	0	0
Microsoft Corporation	Common	594918104	139	1,000	SH		DFND	1	0	1,000	0
Microsoft Corporation	Common	594918104	56	400	SH		DFND	1	400	0	0
Mondelez Int'l Inc.	Common	609207105	719	13,000	SH		DFND	1	0	13,000	0
Mondelez Int'l Inc.	Common	609207105	160	2,900	SH		DFND	1	2,900	0	0
MPLX LP	Common	55336V100	10,267	366,558	SH		DFND	2	366,558	0	0
Novartis AG	Common	66987V109	130	1,500	SH		DFND	2	1,500	0	0
Novelion Therapeutics, Inc.	Common	67001K202	79	109,135	SH		DFND	2	109,135	0	0
Occidental Pete Corp	Common	674599105	57	1,273	SH		DFND	1	0	1,273	0
Occidental Pete Corp	Common	674599105	76	1,700	SH		DFND	1	1,700	0	0
Oritani Financial Corp	Common	68633D103	35	2,000	SH		DFND	1	0	2,000	0
Oritani Financial Corp	Common	68633D103	103	5,800	SH		DFND	1	5,800	0	0
Orthofix Medical Inc.	Common	68752M108	106	2,000	SH		DFND	2	2,000	0	0
Peoples United Financial	Common	712704105	23	1,500	SH		DFND	1	0	1,500	0
Pfizer Inc.	Common	717081103	3,629	101,000	SH		DFND	1	0	101,000	0
Pfizer Inc.	Common	717081103	1,110	30,900	SH		DFND	1	44,000	0	0
Quotient Limited	Common	G73268107	548	70,542	SH		DFND	2	70,542	0	0
Radius Health Inc.	Common	750469207	1,887	73,269	SH		DFND	2	73,269	0	0
RMR Group Inc.	Common	74967R106	1	16	SH		DFND	1	0	16	0
Ryman Hospitality Ppty Inc.	Common	78377T107	982	12,000	SH		DFND	1	0	12,000	0
Ryman Hospitality Ppty Inc.	Common	78377T107	33	400	SH		DFND	1	400	0	0
Sculptor Cap Mgmt	Common	811246107	4	200	SH		DFND	1	200	0	0
Service Ppty Trust	Common	81761L102	26	1,000	SH		DFND	1	0	1,000	0
Starwood Ppty	Common	85571B105	10	400	SH		DFND	1	400	0	0
Stemline Therapeutics, Inc.	Common	85858C107	1,124	107,934	SH		DFND	2	107,934	0	0
Stericycle, Inc.	Common	858912108	15,996	314,083	SH		DFND	2	314,083	0	0
The Michaels Companies, Inc.	Common	59408Q106	1,469	150,000	SH		DFND	2	150,000	0	0
The Kraft Heinz Company	Common	500754106	52	1,865	SH		DFND	1	0	1,865	0
The Kraft Heinz Company	Common	500754106	85	3,035	SH		DFND	1	3,035	0	0
The Stars Group Inc.	Common	85570W100	8,176	545,800	SH		DFND	2	545,800	0	0
Total SA	Common	89151E109	26	500	SH		DFND	1	0	500	0
Total SA	Common	89151E109	123	2,360	SH		DFND	1	2,360	0	0
Upland Software, Inc.	Common	91544A109	15,269	438,000	SH		DFND	2	438,000	0	0
Verizon Communications Inc.	Common	92343V104	1,026	16,991	SH		DFND	1	0	16,991	0
Verizon Communications Inc.	Common	92343V104	80	1,320	SH		DFND	1	1,320	0	0
Verrica Pharmaceuticals, Inc.	Common	92511W108	151	10,207	SH		DFND	2	10,207	0	0
Viking Therapeutics, Inc.	Common	92686J106	1,501	218,102	SH		DFND	2	218,102	0	0
WABTEC	Common	929740108	0	6	SH		DFND	1	0	6	0
WABTEC	Common	929740108	1	17	SH		DFND	1	17	0	0
Wheeler Real Estate Investment Trust, Inc.	Common	963025606	203	14,309	SH		DFND	2	14,309	0	0
WP Carey	Common	92936U109	537	6,000	SH		DFND	1	0	6,000	0
Xenon Pharmaceuticals Inc.	Common	98420N105	1,688	187,311	SH		DFND	2	187,311	0	0