Morgan Stanley Institutional Fund, Inc.
522 Fifth Avenue
New York, New York 10036
November 25, 2014
VIA EDGAR
Securities and Exchange Commission
Judiciary Plaza
100 F Street, NE
Washington, D.C. 20549
Attn: Asen Parachkevov, Division of Investment Management
Re: Morgan Stanley Institutional Fund, Inc.
Securities Act File No. 033-23166
Registration Statement on Form N-1A
Dear Mr. Scott:
In accordance with Rule 461 of the General Rules and Regulations under the Securities Act of 1933, as amended (the “Securities Act”), Morgan Stanley Institutional Fund, Inc. (the “Fund”), on behalf of Emerging Markets Leaders Portfolio, a series of the Fund, hereby requests that the effectiveness for the above-referenced Registration Statement on Form N-1A be accelerated so that it will become effective as soon as practicable on December 10, 2014. The Fund hereby confirms that it is aware of its obligations under the Securities Act and the Securities Exchange Act of 1934, as amended.
| Very truly yours, | |
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| /s/ Mary E. Mullin | |
| Name: | Mary E. Mullin |
| Title: | Secretary |
