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Exhibit 23.1
CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM
We consent to the incorporation by reference in Registration Statement No. 333-163670 on Form S-8 of our report dated March 25, 2013, which includes an explanatory paragraph related to the uncertainty of the Company’s ability to continue as a going concern, relating to the consolidated financial statements of Sorrento Therapeutics, Inc. and Subsidiary for the year ended December 31, 2012, appearing in this Annual Report on Form 10-K of Sorrento Therapeutics, Inc. and Subsidiary.
/s/ Mayer Hoffman McCann P.C.
San Diego, California
March 25, 2013