| Document and Entity Information | May 03, 2021 |
| Cover [Abstract] | |
| Document Type | 8-K |
| Amendment Flag | false |
| Entity Registrant Name | Sarepta Therapeutics, Inc. |
| Entity Central Index Key | 0000873303 |
| Document Period End Date | May 3, 2021 |
| Entity Emerging Growth Company | false |
| Entity File Number | 001-14895 |
| Entity Incorporation, State or Country Code | DE |
| Entity Tax Identification Number | 93-0797222 |
| Entity Address, Address Line One | 215 First Street |
| Entity Address, Address Line Two | Suite 415 |
| Entity Address, City or Town | Cambridge |
| Entity Address, State or Province | MA |
| Entity Address, Postal Zip Code | 02142 |
| City Area Code | 617 |
| Local Phone Number | 274-4000 |
| Written Communications | false |
| Soliciting Material | false |
| Pre-commencement Tender Offer | false |
| Pre-commencement Issuer Tender Offer | false |
| Title of each class | Common Stock, Par Value $0.0001 per share |
| Trading Symbol | SRPT |
| Name of each exchange on which registered | NASDAQ |
