Incyte (INCY) 10-K 2009 FY Annual report

Exhibit 23.1

Consent of Independent Registered Public Accounting Firm

        We consent to the incorporation by reference in the Registration Statements (Form S-8 Nos. 33-93668, 333-91556, 333-125995, and 333-160006) pertaining to the 1993 Directors' Stock Option Plan of Incyte Corporation, (Form S-8 Nos. 333-47178, 333-63069, 333-67598, 333-83291, 333-91542, 333-143753, 333-151716, and 333-160005) pertaining to the 1991 Stock Plan of Incyte Corporation, (Form S-8 Nos. 333-108013, 333-134472, 333-151715, and 333-160007) pertaining to the 1997 Employee Stock Purchase Plan of Incyte Corporation, and (Form S-3 Nos. 333-152611, 333-157751 and Form S-3 MEF No. 333-162056) pertaining to registration of its Debt Securities, Preferred Stock, Common Stock, Depositary Shares and Warrants, as applicable, of our reports dated March 5, 2010, with respect to the consolidated financial statements of Incyte Corporation and the effectiveness of internal control over financial reporting of Incyte Corporation, included in this Annual Report (Form 10-K) for the year ended December 31, 2009.

/s/ ERNST & YOUNG LLP

Philadelphia, Pennsylvania
March 5, 2010