April 23, 2019
| Via EDGAR |
Securities and Exchange Commission 100 F Street N.E. Washington, D.C. 20549-7010 USA
|
| Re: | Aptose Biosciences Inc. Registration Statement on Form S-3 Filed March 12, 2019, as amended File No. 333-230218 |
Pursuant to Rule 461(a) under the Securities Act of 1933, as amended (the “Securities Act”), Aptose Biosciences Inc. (the “Company”) hereby respectfully requests that the Securities and Exchange Commission (the “Commission”) accelerate the effective date of the above-referenced Registration Statement (the “Registration Statement”) to April 25, 2019 at 4:00 p.m. (Eastern) or as soon thereafter as is practicable.
The Company also requests the Commission confirm the effective date and time of the Registration Statement in writing.
| APTOSE BIOSCIENCES INC. | |||
| By | /s/ Gregory K. Chow | ||
| Name: | Gregory K. Chow | ||
| Title: | Senior Vice President & Chief Financial Officer | ||