Exhibit 23.1
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KPMG LLP
Vaughan Metropolitan Centre
100 New Park Place, Suite 1400
Vaughan, ON L4K 0J3
Canada
Tel905-265-5900
Fax905-265-6390
Consent of Independent Registered Public Accounting Firm
The Board of Directors
Aptose Biosciences Inc.
We, KPMG LLP, consent to the incorporation by reference in the registration statement (No.333-[ ]) on FormS-3 of common shares or warrants or any combination of those securities, either individually or in units, up to an aggregate initial offering price of $200,000,000 of Aptose Biosciences Inc. (the Company), of our report dated March 12, 2019, on the consolidated financial statements of the Company, which comprise the consolidated statements of financial position as at December 31, 2018 and December 31, 2017, the related consolidated statements of loss and comprehensive loss, changes in shareholders’ equity and cash flows for each of the years in thetwo-year period ended December 31, 2018, and the related notes, comprising a summary of significant accounting policies and other explanatory information (collectively, the consolidated financial statements), and to the reference to our firm under the heading “Experts” in the registration statement.
Our report dated March 12, 2019 on the consolidated financial statements referred to above contains an explanatory paragraph indicating the Company has retrospectively adopted United States generally accepted accounting principles and changed its functional and presentation currency from Canadian dollars to United States dollars.
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Chartered Professional Accountants, Licensed Public Accountants
December 27, 2019
Vaughan, Canada
KPMG LLP is a Canadian limited liability partnership and a member firm of the KPMG network of independent member firms affiliated with KPMG International Cooperative (“KPMG International”), a Swiss entity. KPMG Canada provides services to KPMG LLP.