Exhibit 23.1
KPMG LLP
100 New Park Place, Suite 1400
Vaughan, ON L4K 0J3
Tel 905-265 5900
Fax 905-265 6390
www.kpmg.ca
Consent of Independent Registered Public Accounting Firm
The Board of Directors
Aptose Biosciences Inc.
We, consent to use of our report dated March 23, 2023, on the consolidated financial statements of Aptose Biosciences Inc., which comprise the consolidated statements of financial position as at December 31, 2022 and December 31, 2021, the related consolidated statements of loss and comprehensive loss, changes in shareholders’ equity and cash flows for the years then ended, and the related notes, which is incorporated by reference, and to the reference to our firm under the heading “Experts”, in the prospectus included in the registration statement (No. 333-[ ]) dated December 1, 2023 on Form S-1 of Aptose Biosciences Inc..
/s/ KPMG LLP
Chartered Professional Accountants, Licensed Public Accountants
December 1, 2023
Vaughan, Canada
KPMG LLP, an Ontario limited liability partnership and member firm of the KPMG global organization of independent member firms affiliated with KPMG International Limited, a private English company limited by guarantee. KPMG Canada provides services to KPMG LLP. Document classification: KPMG Confidential