Exhibit 23.1
KPMG LLP
100 New Park Place, Suite 1400
Vaughan, ON L4K 0J3
Tel 905-265 5900
Fax 905-265 6390
www.kpmg.ca
Consent of Independent Registered Public Accounting Firm
The Board of Directors
Aptose Biosciences Inc.
We consent to use of our report dated March 26, 2024, on the consolidated financial statements of Aptose Biosciences Inc., which comprise the consolidated statements of financial position as at December 31, 2023 and December 31, 2022, the related consolidated statements of loss and comprehensive loss, changes in shareholders’ equity and cash flows for the years then ended, and the related notes, which are incorporated by reference in the registration statement (No. 333-281201) dated October 30, 2024 on Form S-1 of Aptose Biosciences Inc. and to the reference to our firm under the heading “Experts” in the preliminary prospectus included in the registration statement (No. 333-281201) dated October 30, 2024 of Aptose Biosciences Inc.
/s/ KPMG LLP
Chartered Professional Accountants, Licensed Public Accountants
October 30, 2024
Vaughan, Canada
KPMG LLP, an Ontario limited liability partnership and member firm of the KPMG global organization of independent member firms affiliated with KPMG International Limited, a private English company limited by guarantee. KPMG Canada provides services to KPMG LLP. Document classification: KPMG Confidential
