EXHIBIT 21
List of World-wide subsidiaries of Boston Scientific as of February 19, 2010
Structure of ownership and control:
Boston Scientific wholly owns or has a majority interest in all of the below mentioned entities.
| Arter Re Insurance Company, Ltd. (Bermuda) |
| Boston Scientific (2001) Ltd. (Israel) |
| Boston Scientific (Malaysia) Sdn. Bhd. (Malaysia) |
| Boston Scientific (South Africa) (Proprietary) Limited (South Africa) |
| Boston Scientific (Thailand) Ltd. (Thailand) |
| Boston Scientific (UK) Limited (England) |
| Boston Scientific AG (Switzerland) |
| Boston Scientific Argentina S.A. (Argentina) |
| Boston Scientific Asia Pacific Pte. Ltd. (Singapore) |
| Boston Scientific Benelux NV (Belgium) |
| Boston Scientific Capital Japan Nin-I Kumiai (Japan) |
| Boston Scientific Ceska repulika s.r.o. (Czech Republic) |
| Boston Scientific Clonmel Limited (Ireland) |
| Boston Scientific Colombia Limitada (Colombia) |
| Boston Scientific Cork Limited (Ireland) |
| Boston Scientific Corporation Northwest Technology Center, Inc. (Washington) |
| Boston Scientific Danmark ApS (Denmark) |
| Boston Scientific de Costa Rica S.R.L. (Costa Rica) |
| Boston Scientific de Mexico, S.A. de C.V. (Mexico) |
| Boston Scientific de Venezuela, C.A. (Venezuela) |
| Boston Scientific del Caribe, Inc. (Puerto Rico) |
| Boston Scientific Distribution Ireland Limited (Ireland) |
| Boston Scientific do Brasil Ltda. (Brazil) |
| Boston Scientific Eastern Europe B.V. (The Netherlands) |
| Boston Scientific Europe S.P.R.L. (Belgium) |
| Boston Scientific Far East B.V. (The Netherlands) |
| Boston Scientific Foundation, Inc. (Massachusetts) |
| Boston Scientific Funding LLC (Delaware) |
| Boston Scientific Gesellschaft m.b.H. (Austria) |
| Boston Scientific Hellas S.A. — (Greece) |
| Boston Scientific Hong Kong Limited (Hong Kong) |
| Boston Scientific Hungary Trading Limited Liability Company (Hungary) |
| Boston Scientific Iberica, S.A. (Spain) |
| Boston Scientific International B.V. (The Netherlands) |
| Boston Scientific International Finance Limited (Ireland) |
| Boston Scientific International Holding Limited (Ireland) |
| Boston Scientific International Limited (Ireland) |
| Boston Scientific International S.A. (France) |
| Boston Scientific Ireland Limited (Ireland) |
| Boston Scientific Israel Limited (Israel) |
| Boston Scientific Japan K.K. (Japan) |
| Boston Scientific Korea Co., Ltd. (Korea) |
| Boston Scientific Latin America B.V. (Chile) Limitada (Chile) |
| Boston Scientific Latin America B.V. (The Netherlands) |
| Boston Scientific Lebanon SAL (Lebanon) |
| Boston Scientific Limited (England) |
| Boston Scientific Limited (Ireland) |
| Boston Scientific Ltd./Boston Scientifique LTEE (Canada) |
| Boston Scientific Medizintechnik GmbH (Germany) |
| Boston Scientific Miami Corporation (Florida) |
| Boston Scientific Middle East SAL (Offshore) (Lebanon) |
| Boston Scientific Mountain View Corp. (Delaware) |
| Boston Scientific Nederland B.V. (The Netherlands) incorporated |
| Boston Scientific Neuromodulation Corporation (Delaware) |
| Boston Scientific New Zealand Limited (New Zealand) |
| Boston Scientific Norge AS (Norway) |
| Boston Scientific Philippines, Inc. (Philippines) |
| Boston Scientific Polska Sp. Z o.o. (Poland) |
| Boston Scientific Portugal — Dispositivos Medicos, Lda |
| Boston Scientific Pty. Ltd. (Australia) |
| Boston Scientific S.A.S. (France) |
| Boston Scientific S.p.A. (Italy) |
| Boston Scientific Scimed, Inc. (Minnesota) |
| Boston Scientific Suomi Oy (Finland) |
| Boston Scientific Sverige AB (Sweden) |
| Boston Scientific Technologie Zentrum GmbH (Germany) |
| Boston Scientific TIP Gerecleri Limited Sirketi (Turkey) |
| Boston Scientific Tullamore Limited (Ireland) |
| Boston Scientific Uruguay S.A. (Uruguay) |
| Boston Scientific Wayne Corporation (New Jersey) |
| BSC Capital S.à r.l. (Luxembourg) |
| BSC International Holding Limited (Ireland) |
| BSC International Medical Trading (Shanghai) Co., Ltd. (China) |
| BSM Tip Gerecleri Limited Sirketi (Turkey) |
| CAM Acquisition Corp. (Delaware) |
| Cardiac Pacemakers, Inc. (Minnesota) |
| Corvita Corporation (Florida) |
| Corvita Europe S.A. (Belgium) |
| Cryocor, Inc. (Delaware) |
| DCI Merger Corp. (Delaware) |
| EndoVascular Technologies, Inc. (Delaware) |
| Enteric Medical Technologies, Inc. (Delaware) |
| EP Technologies, Inc. (Delaware) |
| ET Acquisition Corp. (California) |
| GCI Acquisition Corp. (Delaware) |
| Guidant (England) |
| Guidant (Thailand) Ltd. (Thailand) |
| Guidant Australia Pty. Ltd. (Australia) |
| Guidant Corporation (Indiana) |
| Guidant do Brasil Ltda.(in dormancy) (Brazil) |
| Guidant Europe NV (Belgium) |
| Guidant Foundation (Indiana) |
| Guidant Group B.V. (Netherlands) |
| Guidant Holdings B.V. (Netherlands) |
| Guidant Holdings, Inc. (Indiana) |
| Guidant Hong Kong Ltd. (Hong Kong) |
| Guidant India Private Limited (India) |
| Guidant Intercontinental Corporation (Indiana) |
| Guidant Investment Corporation (California) |
| Guidant Puerto Rico B.V. (Netherlands) |
| Guidant Sales Corporation (Indiana) |
| Guidant Singapore Pte. Ltd. (Singapore) |
| Intermedics, Inc. (Delaware) |
| InterVentional Technologies Europe Limited (Ireland) |
| Interventional Technologies, LLC (Delaware) |
| Labcoat Limited (Ireland) |
| Precision Vascular Systems, Inc. (Utah) |
| Remon Medical Technologies, Inc. (Delaware) |
| Remon Medical Technologies, Inc. (Israel) |
| RMI Acquisition Corp. (California) |
| Schneider (Europe) GmbH (Switzerland) |
| Stream Enterprises LLC (Delaware) |
| Target Therapeutics, Inc. (Delaware) |