Exhibit 16.1
February 11, 2008
U.S. Securities and Exchange Commission
Office of the Chief Accountant
100 F Street, NE
Washington, DC 20549
Re: Tapestry Pharmaceutical, Inc.
File No. 0-24320
Dear Sir or Madam:
We have read Item 4.01 of Form 8-K of Tapestry Pharmaceuticals, Inc. dated February 11, 2008, and agree with the statements concerning our Firm contained therein.
Very truly yours,
GRANT THORNTON LLP
/s/ Grant Thornton LLP