Document_And_Entity_Informatio
Document And Entity Information | 9 Months Ended | |
Sep. 30, 2013 | Nov. 01, 2013 | |
Document Information [Line Items] | ' | ' |
Document Type | '10-Q | ' |
Amendment Flag | 'false | ' |
Document Period End Date | 30-Sep-13 | ' |
Document Fiscal Year Focus | '2013 | ' |
Document Fiscal Period Focus | 'Q3 | ' |
Trading Symbol | 'RPRX | ' |
Entity Common Stock, Shares Outstanding | ' | 23,009,882 |
Entity Registrant Name | 'REPROS THERAPEUTICS INC. | ' |
Entity Central Index Key | '0000897075 | ' |
Current Fiscal Year End Date | '--12-31 | ' |
Entity Filer Category | 'Accelerated Filer | ' |
CONDENSED_CONSOLIDATED_BALANCE
CONDENSED CONSOLIDATED BALANCE SHEETS (USD $) | Sep. 30, 2013 | Dec. 31, 2012 |
In Thousands, unless otherwise specified | ||
Current Assets | ' | ' |
Cash and cash equivalents | $81,828 | $24,212 |
Prepaid expenses and other current assets | 193 | 406 |
Total current assets | 82,021 | 24,618 |
Fixed assets, net | 87 | 53 |
Other assets, net | 2,734 | 2,161 |
Total assets | 84,842 | 26,832 |
Current Liabilities | ' | ' |
Accounts payable | 2,829 | 3,240 |
Accrued expenses | 382 | 558 |
Total current liabilities | 3,211 | 3,798 |
Commitments and contingencies (note 5) | ' | ' |
Stockholders' Equity | ' | ' |
Undesignated Preferred Stock, $.001 par value, 5,000,000 shares authorized, none issued and outstanding | 0 | 0 |
Common Stock, $.001 par value, 75,000,000 shares authorized, 23,121,959and 17,272,505 shares issued, respectively and 23,009,609 and 17,160,155 shares outstanding, respectively | 23 | 17 |
Additional paid-in capital | 313,469 | 234,299 |
Cost of treasury stock, 112,350 shares | -1,380 | -1,380 |
Deficit accumulated during the development stage | -230,481 | -209,902 |
Total stockholders' equity | 81,631 | 23,034 |
Total liabilities and stockholders' equity | $84,842 | $26,832 |
CONDENSED_CONSOLIDATED_BALANCE1
CONDENSED CONSOLIDATED BALANCE SHEETS (Parenthetical) (USD $) | Sep. 30, 2013 | Dec. 31, 2012 |
Preferred Stock, par value | $0.00 | $0.00 |
Preferred Stock, shares authorized | 5,000,000 | 5,000,000 |
Preferred Stock, issued | 0 | 0 |
Preferred Stock, outstanding | 0 | 0 |
Common Stock, par value | $0.00 | $0.00 |
Common Stock, shares authorized | 75,000,000 | 75,000,000 |
Common Stock, shares issued | 23,121,959 | 17,272,505 |
Common Stock, shares outstanding | 23,009,609 | 17,160,155 |
Treasury stock, shares | 112,350 | 112,350 |
CONDENSED_CONSOLIDATED_STATEME
CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS (USD $) | 3 Months Ended | 9 Months Ended | 313 Months Ended | ||
In Thousands, except Share data, unless otherwise specified | Sep. 30, 2013 | Sep. 30, 2012 | Sep. 30, 2013 | Sep. 30, 2012 | Sep. 30, 2013 |
Revenues | ' | ' | ' | ' | ' |
Licensing fees | $0 | $0 | $0 | $0 | $28,755 |
Product royalties | 0 | 0 | 0 | 0 | 627 |
Research and development grants | 0 | 0 | 0 | 0 | 1,219 |
Interest income | 3 | 1 | 6 | 1 | 16,308 |
Gain on disposal of fixed assets | 0 | 0 | 0 | 0 | 102 |
Other Income | 0 | 0 | 0 | 0 | 1,003 |
Total revenues and other income | 3 | 1 | 6 | 1 | 48,014 |
Expenses | ' | ' | ' | ' | ' |
Research and development | 4,786 | 3,131 | 17,132 | 6,776 | 212,391 |
General and administrative | 1,215 | 1,453 | 3,453 | 3,348 | 56,373 |
Other Expense | 0 | 0 | 0 | 0 | 388 |
Total expenses | 6,001 | 4,584 | 20,585 | 10,124 | 269,152 |
Loss from continuing operations | -5,998 | -4,583 | -20,579 | -10,123 | -221,138 |
Loss from discontinued operations | 0 | 0 | 0 | 0 | -1,828 |
Gain on disposal of discontinued operation | 0 | 0 | 0 | 0 | 939 |
Net loss before cumulative effect of change in accounting principle | -5,998 | -4,583 | -20,579 | -10,123 | -222,027 |
Cumulative effect of change in accounting principle | 0 | 0 | 0 | 0 | -8,454 |
Net loss | ($5,998) | ($4,583) | ($20,579) | ($10,123) | ($230,481) |
Loss per share - basic and diluted: | ($0.26) | ($0.30) | ($1.03) | ($0.69) | ' |
Weighted average shares used in loss per share calculation: | ' | ' | ' | ' | ' |
Basic | 23,006 | 15,422 | 20,066 | 14,746 | ' |
Diluted | 23,006 | 15,422 | 20,066 | 14,746 | ' |
CONSOLIDATED_STATEMENTS_OF_STO
CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY (USD $) | Total | Common Stock | Additional Paid-in Capital | Treasury Stock | Deficit Accumulated During the Development Stage |
In Thousands, except Share data | |||||
Beginning Balance at Dec. 31, 2011 | $4,666 | $12 | $197,769 | ($1,380) | ($191,735) |
Beginning Balance (in shares) at Dec. 31, 2011 | ' | 12,470,694 | ' | 112,350 | ' |
Stock based option compensation | 1,902 | 0 | 1,902 | 0 | 0 |
Issuance of 100 shares of common stock at a share price of $5.07 (in shares) | ' | 100 | ' | 0 | ' |
Issuance of shares of common stock, net of offering costs (in shares) | ' | 2,463,537 | ' | 0 | ' |
Exercise of stock options to purchase common stock for cash | 121 | 0 | 121 | 0 | 0 |
Exercise of stock options to purchase common stock for cash (in shares) | ' | 16,488 | ' | 0 | ' |
Issuance of shares of common stock for the cashless exercise of stock options (in shares) | ' | 11,173 | ' | 0 | ' |
Exercise of Series B Warrants to purchase common stock for cash @ $2.49 per share | 301 | 0 | 301 | 0 | 0 |
Exercise of Series B Warrants to purchase common stock for cash @ $2.49 per share (in shares) | ' | 121,079 | ' | 0 | ' |
Issuance of shares of common stock, net of offering costs 1 | 23,018 | 2 | 23,016 | 0 | 0 |
Issuance of shares of common stock, net of offering costs 1 (in shares) | ' | 2,145,636 | ' | 0 | ' |
Issuance of shares of common stock, net of offering costs | 10,310 | 3 | 10,307 | 0 | 0 |
Net loss | -10,123 | 0 | 0 | 0 | -10,123 |
Ending Balance at Sep. 30, 2012 | 30,195 | 17 | 233,416 | -1,380 | -201,858 |
Ending Balance (in shares) at Sep. 30, 2012 | ' | 17,228,707 | ' | 112,350 | ' |
Beginning Balance at Dec. 31, 2012 | 23,034 | 17 | 234,299 | -1,380 | -209,902 |
Beginning Balance (in shares) at Dec. 31, 2012 | ' | 17,272,505 | ' | 112,350 | ' |
Stock based option compensation | 2,258 | 0 | 2,258 | 0 | 0 |
Issuance of shares of common stock, net of offering costs (in shares) | ' | 4,312,500 | ' | 0 | ' |
Issuance of 871,634 shares of common stock for the cashless exercise of 872,133 Series A Warrants | 0 | 1 | -1 | 0 | 0 |
Issuance of 871,634 shares of common stock for the cashless exercise of 872,133 Series A Warrants (in shares) | ' | 871,634 | ' | 0 | ' |
Issuance of 614,564 shares of common stock for the cashless exercise of 716,463 Series B Warrants | 0 | 1 | -1 | 0 | 0 |
Issuance of 614,564 shares of common stock for the cashless exercise of 716,463 Series B Warrants (in shares) | ' | 614,564 | ' | 0 | ' |
Exercise of stock options to purchase common stock for cash | 47 | 0 | 47 | 0 | 0 |
Exercise of stock options to purchase common stock for cash (in shares) | ' | 2,500 | ' | 0 | ' |
Issuance of shares of common stock for the cashless exercise of stock options (in shares) | ' | 5,407 | ' | 0 | ' |
Exercise of Series B Warrants to purchase common stock for cash @ $2.49 per share | 107 | 0 | 107 | 0 | 0 |
Exercise of Series B Warrants to purchase common stock for cash @ $2.49 per share (in shares) | ' | 42,849 | ' | 0 | ' |
Issuance of shares of common stock, net of offering costs | 76,764 | 4 | 76,760 | 0 | 0 |
Net loss | -20,579 | 0 | 0 | 0 | -20,579 |
Ending Balance at Sep. 30, 2013 | $81,631 | $23 | $313,469 | ($1,380) | ($230,481) |
Ending Balance (in shares) at Sep. 30, 2013 | ' | 23,121,959 | ' | 112,350 | ' |
CONSOLIDATED_STATEMENTS_OF_STO1
CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY (Parenthetical) (USD $) | 9 Months Ended | |
Sep. 30, 2013 | Sep. 30, 2012 | |
Issuance of 871,634 shares of common stock for the cashless exercise of Series A Warrants | 872,133 | ' |
Issuance of shares of common stock for the cashless exercise of Series B Warrants stock options | 716,463 | ' |
Exercise of Series B Warrants to purchase common stock for cash, share price | $2.49 | $2.49 |
Issuance of shares of common stock for the cashless exercise of stock options | 8,332 | 27,915 |
Issuance of shares of common stock, offering costs | $5,200,000 | $777 |
Issuance of 100 shares of common stock at a share price | ' | $5.07 |
Exercise of stock option to purchase common stock for cash, share price | $18.74 | ' |
Sale Of Stock Price Per Shares | ' | $4.50 |
Sale Of Stock Price Per Shares 1 | ' | $11 |
Issuance of shares of common stock, offering costs 1 | ' | $586 |
Maximum [Member] | ' | ' |
Exercise of stock option to purchase common stock for cash, share price | ' | $10.88 |
Minimum [Member] | ' | ' |
Exercise of stock option to purchase common stock for cash, share price | ' | $1.33 |
CONDENSED_CONSOLIDATED_STATEME1
CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS (USD $) | 9 Months Ended | 313 Months Ended | |
In Thousands, unless otherwise specified | Sep. 30, 2013 | Sep. 30, 2012 | Sep. 30, 2013 |
Cash Flows from Operating Activities | ' | ' | ' |
Net loss | ($20,579) | ($10,123) | ($230,481) |
Gain on disposal of discontinued operations | 0 | 0 | -939 |
Gain on disposal of fixed assets | 0 | 0 | -102 |
Adjustments to reconcile net loss to net cash used in operating activities: | ' | ' | ' |
Noncash financing costs | 0 | 0 | 316 |
Noncash inventory impairment | 0 | 0 | 4,417 |
Noncash patent impairment | 0 | 0 | 2,614 |
Noncash other income | 0 | 0 | -709 |
Noncash decrease in accounts payable | 0 | 0 | -1,308 |
Depreciation and amortization | 177 | 106 | 4,478 |
Noncash stock-based compensation | 2,258 | 1,902 | 14,576 |
Common stock issued for agreement not to compete | 0 | 0 | 200 |
Series B Preferred Stock issued for consulting services | 0 | 0 | 18 |
Changes in operating assets and liabilities (net effects of purchase of businesses in 1988 and 1994): | ' | ' | ' |
Increase in receivables | 0 | 0 | -199 |
Increase in inventory | 0 | 0 | -4,447 |
(Increase) decrease in prepaid expenses and other current assets | 213 | -352 | 110 |
Increase (decrease) in accounts payable and accrued expenses | -532 | 367 | 11,087 |
Net cash used in operating activities | -18,463 | -8,100 | -200,369 |
Cash Flows from Investing Activities | ' | ' | ' |
Change in trading marketable securities | 0 | 0 | -191 |
Capital expenditures | -63 | -54 | -2,486 |
Purchase of other assets | -776 | -578 | -6,310 |
Proceeds from sale of PP&E | 0 | 0 | 225 |
Cash acquired in purchase of FTI | 0 | 0 | 3 |
Proceeds from sale of subsidiary, less $12,345 for operating losses during 1990 phase-out period | 0 | 0 | 138 |
Proceeds from sale of the assets of FTI | 0 | 0 | 2,250 |
Increase in net assets held for disposal | 0 | 0 | -213 |
Net cash used in investing activities | -839 | -632 | -6,584 |
Cash Flows from Financing Activities | ' | ' | ' |
Proceeds from issuance of common stock, net of offering costs | 76,764 | 33,328 | 284,195 |
Exercise of stock options & warrants | 154 | 422 | 951 |
Proceeds from a shareholder transaction | 0 | 0 | 327 |
Proceeds from issuance of preferred stock | 0 | 0 | 23,688 |
Purchase of treasury stock | 0 | 0 | -21,487 |
Proceeds from issuance of notes payable | 0 | 0 | 2,839 |
Principal payments on notes payable | 0 | 0 | -1,732 |
Net cash provided by financing activities | 76,918 | 33,750 | 288,781 |
Net increase in cash and cash equivalents | 57,616 | 25,018 | 81,828 |
Cash and cash equivalents at beginning of period | 24,212 | 4,565 | 0 |
Cash and cash equivalents at end of period | $81,828 | $29,583 | $81,828 |
CONDENSED_CONSOLIDATED_STATEME2
CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS (Parenthetical) (USD $) | 313 Months Ended |
In Thousands, unless otherwise specified | Sep. 30, 2013 |
Proceeds from sale of subsidiary, operating losses during 1990 phase-out period | $12,345 |
Organization_Operations_and_Li
Organization, Operations and Liquidity | 9 Months Ended | ||
Sep. 30, 2013 | |||
Organization, Consolidation and Presentation of Financial Statements [Abstract] | ' | ||
Organization, Operations and Liquidity | ' | ||
NOTE 1 — Organization, Operations and Liquidity | |||
Repros Therapeutics Inc. (the “Company”, “RPRX,” “Repros,” or “we,” “us” or “our”) was organized on August 20, 1987. We are a development stage biopharmaceutical company focused on the development of new drugs to treat hormonal and reproductive system disorders. | |||
Our primary product candidate, Androxal®, is a single isomer of clomiphene citrate and is an orally active proprietary small molecule compound. We are developing Androxal® for men of reproductive age with low testosterone levels. Androxal® treats the underlying mechanism that causes secondary hypogonadism and restores normal testicular function. We have completed two pivotal efficacy Phase 3 studies for Androxal® conducted under a Special Protocol Assessment (“SPA”). | |||
Proellex®, our product candidate for female reproductive health, is a new chemical entity that acts as a selective blocker of the progesterone receptor and is being developed for the treatment of symptoms associated with uterine fibroids and endometriosis. We completed a low dose study in late 2011 to demonstrate both safety and signals of efficacy in low oral doses of Proellex® and in November 2012 we initiated a Phase 2 study in the treatment of endometriosis. Additionally, we have completed a Phase 1/2 vaginal administration study for uterine fibroids in the first quarter of 2013. | |||
Our product development pipeline is summarized in the table below: | |||
Product Candidate (Indication) | Status | Next Expected Milestone(s) | |
Androxal® | |||
Secondary Hypogonadism | Phase 3 | Complete DEXA study (Q4 2014) pending FDA guidance | |
Proellex® | |||
Uterine Fibroids | Phase 2B (vaginal) | Initiate a Phase 2B study (vaginal delivery) (Q1 2014) | |
Phase 2 (oral) | Lift full clinical hold and initiate efficacy study (low dose oral) (Q1 2014) | ||
Endometriosis | Phase 2 | Complete Phase 2 study (oral delivery) (Q3 2014) | |
We also continue to maintain our patent portfolio of our phentolamine-based products for the treatment of sexual dysfunction. | |||
On June 25, 2013, we completed a public offering of 4,312,500 shares of our common stock at a price per share of $19.00. Net proceeds to us, after deducting underwriter’s fees and offering expenses, were approximately $76.8 million. | |||
As of September 30, 2013, we had accumulated losses of $230.5 million, approximately $81.8 million in cash and cash equivalents, and our accounts payable and accrued expenses were approximately $3.2 million. We anticipate that our current liquidity will be sufficient to continue the development of our product candidates through the NDA filing of both products. We continue to explore potential corporate partnering opportunities for assistance in the clinical development funding and commercialization of our products, as appropriate; however, there can be no assurance that an acceptable corporate partnering opportunity will be successfully completed or that our current liquidity will be sufficient to fund all of our product development needs. | |||
Patents_and_Patent_Application
Patents and Patent Applications | 9 Months Ended |
Sep. 30, 2013 | |
Goodwill and Intangible Assets Disclosure [Abstract] | ' |
Patents and Patent Applications | ' |
NOTE 2 — Patents and Patent Applications | |
As of September 30, 2013, we had approximately $2,734,000 in capitalized patent and patent application costs reflected on its balance sheet. Of this amount, $1,726,000 relates to patent and patent application costs for Androxal® and $1,008,000 relates to patent and patent application costs for Proellex®. | |
Should we not continue development of either drug candidate or should we not continue as a going concern, the remaining capitalized patent and patent application costs may not be recoverable, which would result in charges to operating results in future periods. | |
Accrued_Expenses
Accrued Expenses | 9 Months Ended | |||||||
Sep. 30, 2013 | ||||||||
Accrued Expenses [Abstract] | ' | |||||||
Accrued Expenses | ' | |||||||
NOTE 3 — Accrued Expenses | ||||||||
Accrued expenses consist of the following (in thousands): | ||||||||
September 30, 2013 | December 31, 2012 | |||||||
Patent costs | $ | 152 | $ | 245 | ||||
Research and development costs | 87 | 192 | ||||||
Personnel related costs | 42 | 30 | ||||||
Other | 101 | 91 | ||||||
Total | $ | 382 | $ | 558 | ||||
Loss_Per_Share
Loss Per Share | 9 Months Ended | |||||||||||||
Sep. 30, 2013 | ||||||||||||||
Earnings Per Share [Abstract] | ' | |||||||||||||
Loss Per Share | ' | |||||||||||||
NOTE 4 — Loss Per Share | ||||||||||||||
Basic loss per share is computed by dividing net loss by the weighted average number of shares of common stock outstanding during the period. Diluted loss per share is computed using the average share price for the period and applying the treasury stock method to potentially dilutive outstanding options. In all applicable periods, all potential common stock equivalents were anti-dilutive and, accordingly, were not included in the computation of diluted loss per share. | ||||||||||||||
The following table presents information necessary to calculate loss per share for the three and nine month periods ended September 30, 2013 and 2012 (in thousands, except per share amounts): | ||||||||||||||
Three Months Ended Sept. 30, | Nine Months Ended Sept. 30, | |||||||||||||
2013 | 2012 | 2013 | 2012 | |||||||||||
Net Loss | $ | -5,998 | $ | -4,583 | $ | -20,579 | $ | -10,123 | ||||||
Average common shares outstanding | 23,006 | 15,422 | 20,066 | 14,746 | ||||||||||
Basic and diluted loss per share | $ | -0.26 | $ | -0.3 | $ | -1.03 | $ | -0.69 | ||||||
Potential common stock of 3,975,430 and 5,264,207 common shares underlying stock options and warrants for the periods ended September 30, 2013 and 2012, respectively, were excluded from the above calculation of diluted loss per share because they were anti-dilutive. Other potential common stock at September 30, 2013 includes Series A Warrants to purchase 877,137 shares of our common stock at an exercise price of $0.01 and Series B Warrants to purchase 810,109 shares of our common stock at an exercise price of $2.49 issued in February 2011. Other potential common stock at September 30, 2012 includes Series A Warrants to purchase 1,749,270 shares of our common stock at an exercise price of $0.01 and Series B Warrants to purchase 1,569,421 shares of our common stock at an exercise price of $2.49 issued in February, 2011. | ||||||||||||||
Commitments_and_Contingencies
Commitments and Contingencies | 9 Months Ended |
Sep. 30, 2013 | |
Commitments and Contingencies Disclosure [Abstract] | ' |
Commitments and Contingencies | ' |
NOTE 5 — Commitments and Contingencies | |
Therapeutic uses of our Androxal product candidate are covered in the United States by eight issued U.S. patents and four pending patent applications. Foreign coverage of therapeutic uses of our Androxal product candidate includes 61 issued foreign patents and 52 foreign pending patent applications. The issued patents and pending applications relate to methods for treating certain conditions including the treatment of testosterone deficiency in men, the treatment of diabetes mellitus Type 2, the treatment of metabolic syndrome and conditions associated therewith, and the treatment of infertility in hypogonadal men. Androxal (the trans-isomer of clomiphene) is purified from clomiphene citrate. A third party individual holds two issued patents related to the use of an anti-estrogen such as clomiphene citrate and others for use in the treatment of androgen deficiency and disorders related thereto. We requested re-examination of one of these patents by the U.S. Patent and Trademark Office (“PTO”) based on prior art. The patent holder amended the claims in the re-examination proceedings, which led the PTO to determine that the amended claims were patentable in view of those publications under consideration and a re-examination certificate was issued. We subsequently filed a second request for re-examination by the PTO in light of a number of additional publications. The request was granted and all of the claims were finally rejected by the PTO in the re-examination. The patent holder appealed the rejections to the PTO Board of Patent Appeals and Interferences (the “PTO Board”) which ultimately reversed the rejections of several dependent claims in view of those publications under consideration. The patent holder filed a Notice of Appeal to the Federal Circuit on September 28, 2010 contesting the rejections maintained by the PTO Board. A decision was rendered by the Federal Circuit on December 12, 2011, affirming the rejection of the appealed claims. The PTO issued an Ex Parte Reexamination Certificate on April 29, 2013, cancelling the rejected claims and confirming patentability of the remaining claims. Nevertheless, we believe that our development of Androxal does not infringe any of the remaining claims and that all of the remaining claims are invalid on various grounds including additional prior art publications. We also believe that the second of these two patents is invalid in view of published prior art not considered by the PTO. If necessary, we intend to vigorously defend any and all claims against the holder of such patents in a court of competent jurisdiction in order to develop Androxal further. Adverse determinations in litigation proceedings could require us to seek licenses from patent holders which may not be available on commercially reasonable terms, or at all, or may subject us to significant liabilities, in which case we may not be able to successfully commercialize or out-license Androxal until such patents expire or are otherwise no longer in force. | |
On July 19, 2013, we received a letter from Dr. Harry Fisch threatening to file a lawsuit against us and two of our executive officers (Joseph S. Podolski, President and Chief Executive Officer and Ron Wiehle, Executive Vice President), seeking addition of Dr. Harry Fisch as an inventor on three of our patents, U.S. Patent Nos. 7,173,064, 7,737,185 and 7,759,360, covering therapeutic uses of Androxal®. We believe that these allegations are without merit and on August 2, 2013, we commenced a lawsuit against Dr. Fisch in the U.S. District Court for the Southern District of Texas seeking a declaratory judgment that he should not be added as inventor to any of these patents. On October 2, 2013, Dr. Fisch filed his answer and counterclaims to our complaint. Dr. Fisch asserted counterclaims seeking correction of inventorship of the three patents at issue to name Dr. Fisch as a co-inventor of the applications leading these patents. Dr. Fisch also seeks reasonable attorney’s fees. Due to the preliminary status of the lawsuit and uncertainties related to litigation, we are unable to evaluate the likelihood of either a favorable or unfavorable outcome. | |
Organization_Operations_and_Li1
Organization, Operations and Liquidity (Tables) | 9 Months Ended | ||
Sep. 30, 2013 | |||
Organization, Consolidation and Presentation of Financial Statements [Abstract] | ' | ||
Product Development Pipeline | ' | ||
Our product development pipeline is summarized in the table below: | |||
Product Candidate (Indication) | Status | Next Expected Milestone(s) | |
Androxal® | |||
Secondary Hypogonadism | Phase 3 | Complete DEXA study (Q4 2014) pending FDA guidance | |
Proellex® | |||
Uterine Fibroids | Phase 2B (vaginal) | Initiate a Phase 2B study (vaginal delivery) (Q1 2014) | |
Phase 2 (oral) | Lift full clinical hold and initiate efficacy study (low dose oral) (Q1 2014) | ||
Endometriosis | Phase 2 | Complete Phase 2 study (oral delivery) (Q3 2014) | |
Accrued_Expenses_Tables
Accrued Expenses (Tables) | 9 Months Ended | |||||||
Sep. 30, 2013 | ||||||||
Accrued Expenses [Abstract] | ' | |||||||
Accrued Expenses | ' | |||||||
Accrued expenses consist of the following (in thousands): | ||||||||
September 30, 2013 | December 31, 2012 | |||||||
Patent costs | $ | 152 | $ | 245 | ||||
Research and development costs | 87 | 192 | ||||||
Personnel related costs | 42 | 30 | ||||||
Other | 101 | 91 | ||||||
Total | $ | 382 | $ | 558 | ||||
Loss_Per_Share_Tables
Loss Per Share (Tables) | 9 Months Ended | |||||||||||||
Sep. 30, 2013 | ||||||||||||||
Earnings Per Share [Abstract] | ' | |||||||||||||
Calculation of Loss Per Share | ' | |||||||||||||
The following table presents information necessary to calculate loss per share for the three and nine month periods ended September 30, 2013 and 2012 (in thousands, except per share amounts): | ||||||||||||||
Three Months Ended Sept. 30, | Nine Months Ended Sept. 30, | |||||||||||||
2013 | 2012 | 2013 | 2012 | |||||||||||
Net Loss | $ | -5,998 | $ | -4,583 | $ | -20,579 | $ | -10,123 | ||||||
Average common shares outstanding | 23,006 | 15,422 | 20,066 | 14,746 | ||||||||||
Basic and diluted loss per share | $ | -0.26 | $ | -0.3 | $ | -1.03 | $ | -0.69 | ||||||
Organization_Operations_and_Li2
Organization, Operations and Liquidity (Product Development Pipeline) (Details) | 9 Months Ended |
Sep. 30, 2013 | |
Androxal [Member] | Secondary Hypogonadism [Member] | ' |
Product Information [Line Items] | ' |
Status | 'Phase 3 |
Next Expected Milestone(s) | 'Complete DEXA study (Q4 2014) pending FDA guidance |
Proellex [Member] | Uterine Fibroids 1 [Member] | ' |
Product Information [Line Items] | ' |
Status | 'Phase 2B (vaginal) |
Next Expected Milestone(s) | 'Initiate a Phase 2B study (vaginal delivery) (Q1 2014) |
Proellex [Member] | Uterine Fibroids 2 [Member] | ' |
Product Information [Line Items] | ' |
Status | 'Phase 2 (oral) |
Next Expected Milestone(s) | 'Lift full clinical hold and initiate efficacy study (low dose oral) (Q1 2014) |
Proellex [Member] | Endometriosis [Member] | ' |
Product Information [Line Items] | ' |
Status | 'Phase 2 |
Next Expected Milestone(s) | 'Complete Phase 2 study (oral delivery) (Q3 2014) |
Organization_Operations_and_Li3
Organization, Operations and Liquidity (Additional Information) (Details) (USD $) | Sep. 30, 2013 | Dec. 31, 2012 | Sep. 30, 2012 | Dec. 31, 2011 | Aug. 19, 1987 | Jun. 25, 2013 |
IPO [Member] | ||||||
Product Information [Line Items] | ' | ' | ' | ' | ' | ' |
Deficit accumulated during the development stage | ($230,481,000) | ($209,902,000) | ' | ' | ' | ' |
Cash and cash equivalents | 81,828,000 | 24,212,000 | 29,583,000 | 4,565,000 | 0 | ' |
Accounts payable and accrued expenses | 3,200,000 | ' | ' | ' | ' | ' |
Common stock issued during the period | ' | ' | ' | ' | ' | 4,312,500 |
Price per share | ' | ' | $5.07 | ' | ' | $19 |
Public Offering Net Proceeds | ' | ' | ' | ' | ' | $76,800,000 |
Patents_and_Patent_Application1
Patents and Patent Applications (Additional Information) (Details) (USD $) | Sep. 30, 2013 | Dec. 31, 2012 |
Finite-Lived Intangible Assets [Line Items] | ' | ' |
Capitalized patent and patent application costs | $2,734,000 | $2,161,000 |
Androxal [Member] | ' | ' |
Finite-Lived Intangible Assets [Line Items] | ' | ' |
Capitalized patent and patent application costs | 1,726,000 | ' |
Proellex [Member] | ' | ' |
Finite-Lived Intangible Assets [Line Items] | ' | ' |
Capitalized patent and patent application costs | $1,008,000 | ' |
Accrued_Expenses_Details
Accrued Expenses (Details) (USD $) | Sep. 30, 2013 | Dec. 31, 2012 |
In Thousands, unless otherwise specified | ||
Schedule Of Accrued Liabilities [Line Items] | ' | ' |
Patent costs | $152 | $245 |
Research and development costs | 87 | 192 |
Personnel related costs | 42 | 30 |
Other | 101 | 91 |
Total | $382 | $558 |
Loss_Per_Share_Calculation_of_
Loss Per Share (Calculation of Loss Per Share) (Details) (USD $) | 3 Months Ended | 9 Months Ended | 313 Months Ended | ||
In Thousands, except Share data, unless otherwise specified | Sep. 30, 2013 | Sep. 30, 2012 | Sep. 30, 2013 | Sep. 30, 2012 | Sep. 30, 2013 |
Net loss | ($5,998) | ($4,583) | ($20,579) | ($10,123) | ($230,481) |
Average common shares outstanding | 23,006 | 15,422 | 20,066 | 14,746 | ' |
Basic and diluted loss per share | ($0.26) | ($0.30) | ($1.03) | ($0.69) | ' |
Loss_Per_Share_Additional_Info
Loss Per Share (Additional Information) (Details) (USD $) | 9 Months Ended | |
Sep. 30, 2013 | Sep. 30, 2012 | |
Earnings Per Share Disclosure [Line Items] | ' | ' |
Anti-dilutive shares of common stock excluded from computation of earning per share | 3,975,430 | 5,264,207 |
Series A Warrants [Member] | ' | ' |
Earnings Per Share Disclosure [Line Items] | ' | ' |
Anti-dilutive shares of common stock excluded from computation of earning per share | 877,137 | 1,749,270 |
Warrants, exercise price per share | 0.01 | 0.01 |
Series B Warrants [Member] | ' | ' |
Earnings Per Share Disclosure [Line Items] | ' | ' |
Anti-dilutive shares of common stock excluded from computation of earning per share | 810,109 | 1,569,421 |
Warrants, exercise price per share | 2.49 | 2.49 |
Commitments_and_Contingencies_
Commitments and Contingencies (Additional Information) (Details) | Sep. 30, 2013 |
Domestic [Member] | ' |
Commitments and Contingencies [Line Items] | ' |
Number of patents | 8 |
Number of pending patent applications | 4 |
Foreign [Member] | ' |
Commitments and Contingencies [Line Items] | ' |
Number of patents | 61 |
Number of pending patent applications | 52 |
Third Party [Member] | ' |
Commitments and Contingencies [Line Items] | ' |
Number of patents | 2 |