Document_And_Entity_Informatio
Document And Entity Information | 3 Months Ended | |
Mar. 31, 2014 | 2-May-14 | |
Document Information [Line Items] | ' | ' |
Document Type | '10-Q | ' |
Amendment Flag | 'false | ' |
Document Period End Date | 31-Mar-14 | ' |
Document Fiscal Year Focus | '2014 | ' |
Document Fiscal Period Focus | 'Q1 | ' |
Trading Symbol | 'RPRX | ' |
Entity Common Stock, Shares Outstanding | ' | 23,097,412 |
Entity Registrant Name | 'REPROS THERAPEUTICS INC. | ' |
Entity Central Index Key | '0000897075 | ' |
Current Fiscal Year End Date | '--12-31 | ' |
Entity Filer Category | 'Accelerated Filer | ' |
CONDENSED_CONSOLIDATED_BALANCE
CONDENSED CONSOLIDATED BALANCE SHEETS (USD $) | Mar. 31, 2014 | Dec. 31, 2013 |
In Thousands, unless otherwise specified | ||
Current Assets | ' | ' |
Cash and cash equivalents | $68,012 | $75,807 |
Prepaid expenses and other current assets | 583 | 189 |
Total current assets | 68,595 | 75,996 |
Fixed assets, net | 64 | 75 |
Other assets, net | 3,150 | 2,906 |
Total assets | 71,809 | 78,977 |
Current Liabilities | ' | ' |
Accounts payable | 3,362 | 2,966 |
Accrued expenses | 547 | 586 |
Total current liabilities | 3,909 | 3,552 |
Commitments & Contingencies (note 6) | ' | ' |
Stockholders' Equity | ' | ' |
Undesignated Preferred Stock, $.001 par value, 5,000,000 shares authorized, none issued and outstanding | 0 | 0 |
Common Stock, $.001 par value, 75,000,000 shares authorized, 23,209,762 and 23,125,565 shares issued, respectively; 23,097,412 and 23,013,215 shares outstanding, respectively | 23 | 23 |
Additional paid-in capital | 315,429 | 314,405 |
Cost of treasury stock, 112,350 shares | -1,380 | -1,380 |
Deficit accumulated during the development stage | -246,172 | -237,623 |
Total stockholders' equity | 67,900 | 75,425 |
Total liabilities and stockholders' equity | $71,809 | $78,977 |
CONDENSED_CONSOLIDATED_BALANCE1
CONDENSED CONSOLIDATED BALANCE SHEETS (Parenthetical) (USD $) | Mar. 31, 2014 | Dec. 31, 2013 |
Common Stock, par value | $0.00 | $0.00 |
Common Stock, shares authorized | 75,000,000 | 75,000,000 |
Common Stock, shares issued | 23,209,762 | 23,125,565 |
Common Stock, shares outstanding | 23,097,412 | 23,013,215 |
Treasury stock, shares | 112,350 | 112,350 |
Undesignated Preferred Stock [Member] | ' | ' |
Preferred Stock, par value | $0.00 | $0.00 |
Preferred Stock, shares authorized | 5,000,000 | 5,000,000 |
Preferred Stock, issued | 0 | 0 |
Preferred Stock, outstanding | 0 | 0 |
CONDENSED_CONSOLIDATED_STATEME
CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS (USD $) | 3 Months Ended | 319 Months Ended | |
In Thousands, except Share data, unless otherwise specified | Mar. 31, 2014 | Mar. 31, 2013 | Mar. 31, 2014 |
Revenues and other income | ' | ' | ' |
Licensing fees | $0 | $0 | $28,755 |
Product royalties | 0 | 0 | 627 |
Research and development grants | 0 | 0 | 1,219 |
Interest income | 2 | 1 | 16,313 |
Gain on disposal of fixed assets | 0 | 0 | 102 |
Other Income | 0 | 0 | 1,003 |
Total revenues and other income | 2 | 1 | 48,019 |
Expenses | ' | ' | ' |
Research and development | 7,325 | 6,308 | 225,496 |
General and administrative | 1,226 | 1,067 | 58,964 |
Other Expense | 0 | 0 | 388 |
Total expenses | 8,551 | 7,375 | 284,848 |
Loss from continuing operations | -8,549 | -7,374 | -236,829 |
Loss from discontinued operations | 0 | 0 | -1,828 |
Gain on disposal of discontinued operation | 0 | 0 | 939 |
Net loss before cumulative effect of change in accounting principle | -8,549 | -7,374 | -237,718 |
Cumulative effect of change in accounting principle | 0 | 0 | -8,454 |
Net loss | ($8,549) | ($7,374) | ($246,172) |
Basic and diluted loss per share | ($0.37) | ($0.41) | ' |
Shares used in loss per share calculation: | ' | ' | ' |
Basic | 23,033 | 18,182 | ' |
Diluted | 23,033 | 18,182 | ' |
CONSOLIDATED_STATEMENTS_OF_STO
CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY (USD $) | Total | Common Stock | Additional Paid-in Capital | Treasury Stock | Deficit Accumulated During the Development Stage |
In Thousands, except Share data | |||||
Beginning Balance at Dec. 31, 2012 | $23,034 | $17 | $234,299 | ($1,380) | ($209,902) |
Beginning Balance (in shares) at Dec. 31, 2012 | ' | 17,272,505 | ' | 112,350 | ' |
Stock based option compensation | 629 | 0 | 629 | 0 | 0 |
Issuance of 871,634 shares of common stock for the cashless exercise of 872,133 Series A Warrants | 0 | 1 | -1 | 0 | 0 |
Issuance of 871,634 shares of common stock for the cashless exercise of 872,133 Series A Warrants (in shares) | ' | 871,634 | ' | 0 | ' |
Issuance of 612,197 shares of common stock for the cashless exercise of 713,741 Series B Warrants | 0 | 1 | -1 | 0 | 0 |
Issuance of 612,197 shares of common stock for the cashless exercise of 713,741 Series B Warrants (in shares) | ' | 612,197 | ' | 0 | ' |
Net loss | -7,374 | 0 | 0 | 0 | -7,374 |
Ending Balance at Mar. 31, 2013 | 16,289 | 19 | 234,926 | -1,380 | -217,276 |
Ending Balance (in shares) at Mar. 31, 2013 | ' | 18,756,336 | ' | 112,350 | ' |
Beginning Balance at Dec. 31, 2013 | 75,425 | 23 | 314,405 | -1,380 | -237,623 |
Beginning Balance (in shares) at Dec. 31, 2013 | ' | 23,125,565 | ' | 112,350 | ' |
Stock based option compensation | 920 | 0 | 920 | 0 | 0 |
Exercise of stock options to purchase common stock stock for cash ($1.56 to $9.60 per share) | 104 | 0 | 104 | 0 | 0 |
Exercise of stock options to purchase common stock stock for cash ($1.56 to $9.60 per share) (in shares) | ' | 15,000 | ' | 0 | ' |
Issuance of 69,197 shares of common stock for the cashless exercise of 91,664 stock options | ' | 69,197 | ' | 0 | ' |
Net loss | -8,549 | 0 | 0 | 0 | -8,549 |
Ending Balance at Mar. 31, 2014 | $67,900 | $23 | $315,429 | ($1,380) | ($246,172) |
Ending Balance (in shares) at Mar. 31, 2014 | ' | 23,209,762 | ' | 112,350 | ' |
CONSOLIDATED_STATEMENTS_OF_STO1
CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY (Parenthetical) (USD $) | 3 Months Ended | |
Mar. 31, 2014 | Mar. 31, 2013 | |
Issuance of shares of common stock for the cashless exercise of Series A Warrants stock options | 872,133 | ' |
Issuance of shares of common stock for the cashless exercise of Series B Warrants stock options | ' | 713,741 |
Issuance of shares of common stock for the cashless exercise of stock options | 91,664 | ' |
Maximum [Member] | ' | ' |
Exercise of stock option to purchase common stock for cash, share price | 9.6 | ' |
Minimum [Member] | ' | ' |
Exercise of stock option to purchase common stock for cash, share price | 1.56 | ' |
CONDENSED_CONSOLIDATED_STATEME1
CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS (USD $) | 3 Months Ended | 319 Months Ended | |
In Thousands, unless otherwise specified | Mar. 31, 2014 | Mar. 31, 2013 | Mar. 31, 2014 |
Cash Flows from Operating Activities | ' | ' | ' |
Net loss | ($8,549) | ($7,374) | ($246,172) |
Gain on disposal of discontinued operations | 0 | 0 | -939 |
Gain on disposal of fixed assets | 0 | 0 | -102 |
Adjustments to reconcile net loss to net cash used in operating activities: | ' | ' | ' |
Noncash financing costs | 0 | 0 | 316 |
Noncash inventory impairment | 0 | 0 | 4,417 |
Noncash patent impairment | 0 | 0 | 2,614 |
Noncash other income | ' | ' | -709 |
Noncash decrease in accounts payable | 0 | 0 | -1,308 |
Depreciation and amortization | 58 | 53 | 4,616 |
Noncash stock-based compensation | 920 | 629 | 16,396 |
Common stock issued for agreement not to compete | 0 | 0 | 200 |
Series B Preferred Stock issued for consulting services | 0 | 0 | 18 |
Changes in operating assets and liabilities (net effects of purchase of businesses in 1988 and 1994): | ' | ' | ' |
Increase in receivables | 0 | 0 | -199 |
Increase in inventory | 0 | 0 | -4,447 |
(Increase) decrease in prepaid expenses and other current assets | -393 | 51 | -280 |
Increase (decrease) in accounts payable and accrued expenses | 350 | -121 | 11,611 |
Net cash used in operating activities | -7,614 | -6,762 | -213,968 |
Cash Flows from Investing Activities | ' | ' | ' |
Change in trading marketable securities | 0 | 0 | -191 |
Capital expenditures | 0 | -45 | -2,486 |
Purchase of other assets | -285 | -255 | -6,667 |
Proceeds from sale of fixed assets | 0 | 0 | 225 |
Cash acquired in purchase of FTI | 0 | 0 | 3 |
Proceeds from sale of subsidiary, less $12,345 for operating losses during 1990 phase-out period | 0 | 0 | 138 |
Proceeds from sale of the assets of FTI | 0 | 0 | 2,250 |
Increase in net assets held for disposal | 0 | 0 | -213 |
Net cash used in investing activities | -285 | -300 | -6,941 |
Cash Flows from Financing Activities | ' | ' | ' |
Proceeds from issuance of common stock and warrants, net of offering costs | 0 | 0 | 284,195 |
Exercise of stock options & warrants | 104 | 0 | 1,091 |
Proceeds from a shareholder transaction | 0 | 0 | 327 |
Proceeds from issuance of preferred stock | 0 | 0 | 23,688 |
Purchase of treasury stock | 0 | 0 | -21,487 |
Proceeds from issuance of notes payable | 0 | 0 | 2,839 |
Principal payments on notes payable | 0 | 0 | -1,732 |
Net cash provided by financing activities | 104 | 0 | 288,921 |
Net increase (decrease) in cash and cash equivalents | -7,795 | -7,062 | 68,012 |
Cash and cash equivalents at beginning of period | 75,807 | 24,212 | 0 |
Cash and cash equivalents at end of period | $68,012 | $17,150 | $68,012 |
CONDENSED_CONSOLIDATED_STATEME2
CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS (Parenthetical) (USD $) | 3 Months Ended |
In Thousands, unless otherwise specified | Mar. 31, 2014 |
Proceeds from sale of subsidiary, operating losses during 1990 phase-out period | $12,345 |
Organization_Operations_and_Li
Organization, Operations and Liquidity | 3 Months Ended | ||||
Mar. 31, 2014 | |||||
Organization, Consolidation and Presentation of Financial Statements [Abstract] | ' | ||||
Organization, Operations and Liquidity | ' | ||||
NOTE 1 — Organization, Operations and Liquidity | |||||
Repros Therapeutics Inc. (the “Company,” “RPRX,” “Repros,” or “we,” “us” or “our”) was organized on August 20, 1987. We are a development stage biopharmaceutical company focused on the development of new drugs to treat hormonal and reproductive system disorders. | |||||
Our primary product candidate, Androxal®, is a single isomer of clomiphene citrate and is an orally active proprietary small molecule compound. We are developing Androxal® for men of reproductive age with low testosterone levels. Androxal® treats the underlying mechanism that causes secondary hypogonadism and restores normal testicular function. We have completed two pivotal Phase 3 efficacy studies and we are currently conducting two Phase 3 studies, ZA-304 and ZA-305, against approved testosterone replacement products. | |||||
Proellex®, our product candidate for female reproductive health, is a new chemical entity that acts as a selective blocker of the progesterone receptor and is being developed for the treatment of symptoms associated with uterine fibroids and endometriosis. We completed a dose escalating study to demonstrate both safety and efficacy signals in low oral doses of Proellex® and we are conducting a Phase 2 study in the treatment of endometriosis. Additionally, the Food and Drug Administration has accepted an Investigational New Drug Application for vaginally delivered Proellex®. As a result, we completed a Phase 1/2 vaginal administration study for uterine fibroids. | |||||
Our product development pipeline, with dates as expected as of the date of this report, is summarized in the table below: | |||||
Product Candidate (Indication) | Status | Next Expected Milestone(s) | |||
Androxal® | |||||
Secondary Hypogonadism | Phase 3 | Complete DEXA study (Q4 2014) | |||
Complete ZA-304 and ZA-305 studies (Q4 2014) | |||||
Proellex® | |||||
Uterine Fibroids | Phase 2 | Initiate a Phase 2B study (vaginal delivery) (2014) | |||
Submit Phase 2 study protocol to FDA (oral delivery) (2014) | |||||
Endometriosis | Phase 2 | Fully enroll Phase 2 study (oral delivery) (2014) | |||
As of March 31, 2014, we had accumulated losses of $246.2 million, approximately $68.0 million in cash and cash equivalents, and accounts payable and accrued expenses of approximately $3.9 million, in the aggregate. We anticipate that our current liquidity will be sufficient to continue the development of our product candidates through the New Drug Application filing of both products. We continue to explore potential corporate partnering opportunities for assistance in the clinical development funding and commercialization of our products, as appropriate; however, there can be no assurance that an acceptable corporate partnering opportunity will be successfully completed or that our current liquidity will be sufficient to fund all of our product development needs. | |||||
Patents_and_Patent_Application
Patents and Patent Applications | 3 Months Ended |
Mar. 31, 2014 | |
Goodwill and Intangible Assets Disclosure [Abstract] | ' |
Patents and Patent Applications | ' |
NOTE 2 — Patents and Patent Applications | |
As of March 31, 2014, the Company had approximately $3,150,000 in capitalized patent and patent application costs reflected on its balance sheet. Of this amount, $1,844,000 relates to Androxal® and $1,306,000 relates Proellex®. | |
Should the Company not continue development of either drug candidate or should the Company not continue as a going concern, the remaining capitalized patent costs may not be recoverable, which would result in charges to operating results in future periods. | |
Accrued_Expenses
Accrued Expenses | 3 Months Ended | |||||||
Mar. 31, 2014 | ||||||||
Accrued Expenses [Abstract] | ' | |||||||
Accrued Expenses | ' | |||||||
NOTE 3 — Accrued Expenses | ||||||||
Accrued expenses consist of the following (in thousands): | ||||||||
March 31, 2014 | December 31, 2013 | |||||||
Research and development costs | $ | 234 | $ | 89 | ||||
Patent costs | 224 | 188 | ||||||
Personnel related costs | 42 | 196 | ||||||
Other | 47 | 113 | ||||||
Total | $ | 547 | $ | 586 | ||||
Loss_Per_Share
Loss Per Share | 3 Months Ended | |||||||
Mar. 31, 2014 | ||||||||
Earnings Per Share [Abstract] | ' | |||||||
Loss Per Share | ' | |||||||
NOTE 4 — Loss Per Share | ||||||||
Basic loss per share is computed by dividing net loss by the weighted average number of shares of common stock outstanding during the period. Diluted loss per share is computed using the average share price for the period and applying the treasury stock method to potentially dilutive outstanding options. In all applicable periods, all potential common stock equivalents were anti-dilutive and, accordingly, were not included in the computation of diluted loss per share. | ||||||||
The following table presents information necessary to calculate loss per share for the three month periods ended March 31, 2014 and 2013 (in thousands, except per share amounts): | ||||||||
Three Months Ended March 31, | ||||||||
2014 | 2013 | |||||||
Net loss | $ | -8,549 | $ | -7,374 | ||||
Average common shares outstanding | 23,033 | 18,182 | ||||||
Basic and diluted loss per share | $ | -0.37 | $ | -0.41 | ||||
Potential common stock of 4,086,885 and 3,968,500 common shares underlying stock options and warrants for the periods ended March 31, 2014 and 2013, respectively, were excluded from the above calculation of diluted loss per share because they were anti-dilutive. Other potential common stock at March 31, 2014 includes Series A Warrants to purchase 877,137 shares of our common stock at an exercise price of $0.01 and Series B Warrants to purchase 809,805 shares of our common stock at an exercise price of $2.49 issued in our February 8, 2011 public offering. Other potential common stock at March 31, 2013 includes Series A Warrants to purchase 877,137 shares of our common stock at an exercise price of $0.01 and Series B Warrants to purchase 855,680 shares of our common stock at an exercise price of $2.49 issued in our February 8, 2011 public offering. | ||||||||
StockBased_Compensation
Stock-Based Compensation | 3 Months Ended |
Mar. 31, 2014 | |
Disclosure of Compensation Related Costs, Share-based Payments [Abstract] | ' |
Disclosure of Compensation Related Costs, Share-based Payments [Text Block] | ' |
NOTE 5 — Stock-Based Compensation | |
During the three month period ended March 31, 2014, the Compensation Committee of the Company’s Board of Directors approved grants of options to purchase 273,000 shares of our common stock to employees under the 2011 Equity Incentive Plan. All of these options vest over a three year period. Additionally, during the three month period ended March 31, 2014, 111,244 options either expired or were forfeited. | |
Commitments_and_Contingencies
Commitments and Contingencies | 3 Months Ended |
Mar. 31, 2014 | |
Commitments and Contingencies Disclosure [Abstract] | ' |
Commitments and Contingencies | ' |
NOTE 6 — Commitments and Contingencies | |
Therapeutic uses of our Androxal® product candidate are covered in the United States by nine issued U.S. patents and five pending patent applications. Foreign coverage of therapeutic uses of our Androxal® product candidate includes 66 issued foreign patents and 65 foreign pending patent applications. The issued patents and pending applications relate to methods for treating certain conditions including the treatment of testosterone deficiency in men, the treatment of diabetes mellitus Type 2, the treatment of metabolic syndrome and conditions associated therewith, and the treatment of infertility in hypogonadal men. Androxal® (the trans-isomer of clomiphene) is purified from clomiphene citrate. A third party individual holds two issued patents related to the use of anti-estrogen such as clomiphene citrate and others for use in the treatment of disorders related to androgen deficiency. We requested re-examination of one of these patents by the U.S. Patent and Trademark Office (“PTO”) based on prior art. The patent holder amended the claims in the re-examination proceedings, which led the PTO to determine that the amended claims were patentable in view of those publications under consideration and a re-examination certificate was issued. We subsequently filed a second request for re-examination by the PTO in light of a number of additional publications. The request was granted and all of the claims were finally rejected by the PTO in the re-examination. The patent holder appealed the rejections to the PTO Board of Patent Appeals and Interferences (the “PTO Board”) which ultimately reversed the rejections of several dependent claims in view of those publications under consideration. The patent holder filed a Notice of Appeal to the Federal Circuit on September 28, 2010 contesting the rejections maintained by the PTO Board. A decision was rendered by the Court of Appeals for the Federal Circuit on December 12, 2011, affirming the rejection of the appealed claims. The PTO issued an Ex Parte Reexamination Certificate on April 29, 2013, canceling the rejected claims and confirming the patentability of the remaining claims. Nevertheless, we believe that our development of Androxal® does not infringe any of the remaining claims and that all of the remaining claims are invalid on various grounds including additional prior art publications. We also believe that the second of these two patents is invalid in view of published prior art not considered by the PTO. If necessary, we intend to vigorously defend any and all claims that may be brought by the holder of such patents in a court of competent jurisdiction in order to develop Androxal® further. Adverse determinations in litigation proceedings could require us to seek licenses which may not be available on commercially reasonable terms, or at all, or subject us to significant liabilities, in which case we may not be able to successfully commercialize or out-license Androxal® until such patents expire or are otherwise no longer in force. | |
On July 19, 2013, we received a letter from Dr. Harry Fisch threatening to file a lawsuit against us and two of our executive officers (Joseph S. Podolski, President and Chief Executive Officer and Ron Wiehle, Executive Vice President), seeking addition of Dr. Harry Fisch as an inventor on three of our patents, U.S. Patent Nos. 7,173,064, 7,737,185 and 7,759,360, covering therapeutic uses of Androxal®. We believe that these allegations are without merit and on August 2, 2013, we commenced a lawsuit against Dr. Fisch in the U.S. District Court for the Southern District of Texas seeking a declaratory judgment that he should not be added as an inventor to any of these patents. On October 2, 2013, Dr. Fisch filed his answer and counterclaims to our complaint. Dr. Fisch asserted counterclaims seeking correction of inventorship of the three patents at issue to name Dr. Fisch as a co-inventor of the applications leading these patents. Dr. Fisch subsequently stipulated that he does not claim to be a co-inventor of U.S. Patent No. 7,173,064. Dr. Fisch also seeks reasonable attorney’s fees. Due to the preliminary status of the lawsuit and uncertainties related to litigation, we are unable to evaluate the likelihood of either a favorable or unfavorable outcome. | |
Accrued_Expenses_Tables
Accrued Expenses (Tables) | 3 Months Ended | |||||||
Mar. 31, 2014 | ||||||||
Accrued Expenses [Abstract] | ' | |||||||
Accrued Expenses | ' | |||||||
Accrued expenses consist of the following (in thousands): | ||||||||
March 31, 2014 | December 31, 2013 | |||||||
Research and development costs | $ | 234 | $ | 89 | ||||
Patent costs | 224 | 188 | ||||||
Personnel related costs | 42 | 196 | ||||||
Other | 47 | 113 | ||||||
Total | $ | 547 | $ | 586 | ||||
Loss_Per_Share_Tables
Loss Per Share (Tables) | 3 Months Ended | |||||||
Mar. 31, 2014 | ||||||||
Earnings Per Share [Abstract] | ' | |||||||
Calculation of Loss Per Share | ' | |||||||
The following table presents information necessary to calculate loss per share for the three month periods ended March 31, 2014 and 2013 (in thousands, except per share amounts): | ||||||||
Three Months Ended March 31, | ||||||||
2014 | 2013 | |||||||
Net loss | $ | -8,549 | $ | -7,374 | ||||
Average common shares outstanding | 23,033 | 18,182 | ||||||
Basic and diluted loss per share | $ | -0.37 | $ | -0.41 | ||||
Organization_Operations_and_Li1
Organization, Operations and Liquidity (Product Development Pipeline) (Details) | 3 Months Ended |
Mar. 31, 2014 | |
Androxal [Member] | Secondary Hypogonadism [Member] | ' |
Product Information [Line Items] | ' |
Status | 'Phase 3 |
Next Expected Milestone(s) | 'Complete DEXA study (Q4 2014) Complete ZA-304 and ZA-305 studies (Q4 2014) |
Proellex [Member] | Uterine Fibroids 1 [Member] | ' |
Product Information [Line Items] | ' |
Status | 'Phase 2 |
Next Expected Milestone(s) | 'Initiate a Phase 2B study (vaginal delivery) (2014) Submit Phase 2 study protocol to FDA (oral delivery) (2014) |
Proellex [Member] | Endometriosis [Member] | ' |
Product Information [Line Items] | ' |
Status | 'Phase 2 |
Next Expected Milestone(s) | 'Fully enroll Phase 2 study (oral delivery) (2014) |
Organization_Operations_and_Li2
Organization, Operations and Liquidity (Additional Information) (Details) (USD $) | Mar. 31, 2014 | Dec. 31, 2013 | Mar. 31, 2013 | Dec. 31, 2012 | Aug. 19, 1987 |
Product Information [Line Items] | ' | ' | ' | ' | ' |
Deficit accumulated during the development stage | ($246,172,000) | ($237,623,000) | ' | ' | ' |
Cash and cash equivalents | 68,012,000 | 75,807,000 | 17,150,000 | 24,212,000 | 0 |
Accounts payable and accrued expenses | $3,900,000 | ' | ' | ' | ' |
Patents_and_Patent_Application1
Patents and Patent Applications (Additional Information) (Details) (USD $) | Mar. 31, 2014 | Dec. 31, 2013 |
Finite-Lived Intangible Assets [Line Items] | ' | ' |
Capitalized patent and patent application costs | $3,150,000 | $2,906,000 |
Androxal [Member] | ' | ' |
Finite-Lived Intangible Assets [Line Items] | ' | ' |
Capitalized patent and patent application costs | 1,844,000 | ' |
Proellex [Member] | ' | ' |
Finite-Lived Intangible Assets [Line Items] | ' | ' |
Capitalized patent and patent application costs | $1,306,000 | ' |
Accrued_Expenses_Details
Accrued Expenses (Details) (USD $) | Mar. 31, 2014 | Dec. 31, 2013 |
In Thousands, unless otherwise specified | ||
Schedule Of Accrued Liabilities [Line Items] | ' | ' |
Research and development costs | $234 | $89 |
Patent costs | 224 | 188 |
Personnel related costs | 42 | 196 |
Other | 47 | 113 |
Total | $547 | $586 |
Loss_Per_Share_Calculation_of_
Loss Per Share (Calculation of Loss Per Share) (Details) (USD $) | 3 Months Ended | 319 Months Ended | |
In Thousands, except Share data, unless otherwise specified | Mar. 31, 2014 | Mar. 31, 2013 | Mar. 31, 2014 |
Net loss | ($8,549) | ($7,374) | ($246,172) |
Average common shares outstanding | 23,033 | 18,182 | ' |
Basic and diluted loss per share | ($0.37) | ($0.41) | ' |
Loss_Per_Share_Additional_Info
Loss Per Share (Additional Information) (Details) (USD $) | 3 Months Ended | |
Mar. 31, 2014 | Mar. 31, 2013 | |
Earnings Per Share Disclosure [Line Items] | ' | ' |
Anti-dilutive shares of common stock excluded from computation of earning per share | 4,086,885 | 3,968,500 |
Series A Warrants [Member] | ' | ' |
Earnings Per Share Disclosure [Line Items] | ' | ' |
Anti-dilutive shares of common stock excluded from computation of earning per share | 877,137 | 877,137 |
Warrants, exercise price per share | 0.01 | 0.01 |
Series B Warrants [Member] | ' | ' |
Earnings Per Share Disclosure [Line Items] | ' | ' |
Anti-dilutive shares of common stock excluded from computation of earning per share | 809,805 | 855,680 |
Warrants, exercise price per share | 2.49 | 2.49 |
StockBased_Compensation_Additi
Stock-Based Compensation (Additional Information) (Details) (2011 Equity Incentive Plan Member) | 3 Months Ended |
Mar. 31, 2014 | |
2011 Equity Incentive Plan Member | ' |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] | ' |
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Gross | 273,000 |
Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Period | '3 years |
Share-based Compensation Arrangement by Share-based Payment Award, Options, Forfeitures in Period | 111,244 |
Commitments_and_Contingencies_
Commitments and Contingencies (Additional Information) (Details) | Mar. 31, 2014 |
Domestic [Member] | ' |
Commitments and Contingencies [Line Items] | ' |
Number of patents | 9 |
Number of pending patent applications | 5 |
Foreign [Member] | ' |
Commitments and Contingencies [Line Items] | ' |
Number of patents | 66 |
Number of pending patent applications | 65 |
Third Party [Member] | ' |
Commitments and Contingencies [Line Items] | ' |
Number of patents | 2 |