IMS Health HQ Limited
7, Harewood Avenue
London NW1 6JB
AstraZeneca PLC
Legal & Secretary’s Department
2 Kingdom Street
London
W2 6BD
For the attention of Adrian Kemp
By fax 020 7604 8151 & by post
21 December 2010
Dear Ladies and Gentlemen
In connection with the filing of the accompanying Registration Statement on Form F-3 (the “Form F-3”) of AstraZeneca PLC (“AstraZeneca”), IMS Health hereby authorises AstraZeneca to refer to IMS Health and certain pharmaceutical industry data derived by IMS Health, as identified on the pages included in Exhibit 15.4 to AstraZeneca’s Annual Report and Form 20-F Information for the fiscal year ended December 31, 2009 (the “Annual Report”), which Annual Report is incorporated by reference in the accompanying Form F-3 of AstraZeneca, subject to the same acknowledgements and agreements as set forth in our letter from IMS Health HQ Limited to AstraZeneca PLC, dated 23 March 2010 and included in Exhibit 15.4 to the Annual Report.
Please indicate your agreement to the foregoing by signing in the space indicated below. Our authorisation will not become effective until accepted and agreed by AstraZeneca.
Very truly yours,
/s/ James E. Salitan
James E. Salitan
Vice President and Associate General Counsel, EMEA Region
For and on behalf of IMS Health HQ Limited
ACCEPTED AND AGREED
this 21st day of December 2010
AstraZeneca PLC
By: /s/ Adrian Kemp
Name: Adrian Kemp
Title: Company Secretary
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