| COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 |
| | | VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY |
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | (x$1000) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
| 2U INC COM USD0.001 | COM | 90214J101 | 107,123 | 3,553,012 | SH | | DFND | | 876,694 | 0 | 2,676,318 |
| ABIOMED INC | COM | 003654100 | 1,760 | 15,623 | SH | | DFND | | 4,112 | 0 | 11,511 |
| ABRAXAS PETE CORP | COM | 003830106 | 1,192 | 463,713 | SH | | DFND | | 48,644 | 0 | 415,069 |
| ACACIA COMMUNICATIONS INC COM | COM | 00401C108 | 58,547 | 948,131 | SH | | DFND | | 175,123 | 0 | 773,008 |
| ACADIA HEALTHCARE COMPANY INC COM | COM | 00404A109 | 249 | 7,531 | SH | | DFND | | 212 | 0 | 7,319 |
| ACADIA PHARMACEUTICALS INC COM | COM | 004225108 | 28 | 971 | SH | | DFND | | 170 | 0 | 801 |
| ACCENTURE PLC CLS A USD0.0000225 | COM | G1151C101 | 822 | 7,020 | SH | | DFND | | 1,598 | 0 | 5,422 |
| ACTIVISION BLIZZARD INC COM | COM | 00507V109 | 65,934 | 1,825,927 | SH | | DFND | | 349,305 | 0 | 1,476,622 |
| ADESTO TECHNOLOGIES CORP COM | COM | 00687D101 | 2,395 | 1,294,855 | SH | | DFND | | 132,281 | 0 | 1,162,574 |
| ADIDAS AG NPV (REGD) ISIN #DE000A1EWWW0 SEDOL #4031976 | COM | D0066B185 | 18,771 | 118,802 | SH | | DFND | | 50,798 | 0 | 68,004 |
| ADOBE SYS INC | COM | 00724F101 | 48,398 | 470,116 | SH | | DFND | | 130,999 | 0 | 339,117 |
| ADVANCE AUTO PARTS INC COM | COM | 00751Y106 | 80 | 472 | SH | | DFND | | 13 | 0 | 459 |
| ADVANCED DRAINAGE SYSTEM COM USD0.01 | COM | 00790R104 | 103 | 4,997 | SH | | DFND | | 0 | 0 | 4,997 |
| ADVERUM BIOTECHNOLOGIES INC COM | COM | 00773U108 | 148 | 50,876 | SH | | DFND | | 20,510 | 0 | 30,366 |
| ALIBABA GROUP HLDG LTD | COM | 01609W102 | 24,015 | 273,486 | SH | | DFND | | 100,274 | 0 | 173,212 |
| ALIGN TECHNOLOGY INC COM | COM | 016255101 | 57,433 | 597,451 | SH | | DFND | | 53,706 | 0 | 543,745 |
| ALLEGIANT TRAVEL CO COM | COM | 01748X102 | 20,205 | 121,424 | SH | | DFND | | 8,169 | 0 | 113,255 |
| ALLERGAN PLC. COM USD0.0001 | COM | G0177J108 | 348 | 1,658 | SH | | DFND | | 46 | 0 | 1,612 |
| ALMOST FAMILY INC | COM | 020409108 | 5,535 | 125,520 | SH | | DFND | | 21,597 | 0 | 103,923 |
| ALNYLAM PHARMACEUTICALS INC | COM | 02043Q107 | 46,081 | 1,230,794 | SH | | DFND | | 293,532 | 0 | 937,262 |
| ALPHABET INC CAP STK CL A | COM | 02079K305 | 39,323 | 49,622 | SH | | DFND | | 4,965 | 0 | 44,657 |
| ALPHABET INC CAP STK CL C | COM | 02079K107 | 81,037 | 104,995 | SH | | DFND | | 19,424 | 0 | 85,571 |
| AMAZON.COM INC | COM | 023135106 | 438,551 | 584,836 | SH | | DFND | | 210,921 | 0 | 373,915 |
| AMBER ROAD INC COM USD0.001 | COM | 02318Y108 | 677 | 74,549 | SH | | DFND | | 7,099 | 0 | 67,450 |
| AMEDISYS INC COM | COM | 023436108 | 35,136 | 824,202 | SH | | DFND | | 405,281 | 0 | 418,921 |
| AMERICAN INTL GROUP INC COM NEW | COM | 026874784 | 216 | 3,303 | SH | | DFND | | 91 | 0 | 3,212 |
| AMERICAN TOWER CORPORATION | COM | 03027X100 | 9,549 | 90,359 | SH | | DFND | | 7,562 | 0 | 82,797 |
| APACHE CORP | COM | 037411105 | 109,308 | 1,722,204 | SH | | DFND | | 193,469 | 0 | 1,528,735 |
| APPLE INC | COM | 037833100 | 3,583 | 30,933 | SH | | DFND | | 8,322 | 0 | 22,611 |
| APPLIED OPTOELECTRONICS INC COM | COM | 03823U102 | 9,826 | 419,184 | SH | | DFND | | 57,118 | 0 | 362,066 |
| ARCH COAL INC CL A | COM | 039380407 | 287 | 3,673 | SH | | DFND | | 703 | 0 | 2,970 |
| ARISTA NETWORKS INC COM USD0.0001 | COM | 040413106 | 68,772 | 710,670 | SH | | DFND | | 36,233 | 0 | 674,437 |
| ASHTEAD GROUP ORD GBP0.10 ISIN #GB0000536739 SEDOL #0053673 | COM | G05320109 | 160 | 8,218 | SH | | DFND | | 4,590 | 0 | 3,628 |
| AT HOME GROUP INC COM | COM | 04650Y100 | 1,516 | 103,652 | SH | | DFND | | 9,951 | 0 | 93,701 |
| ATHENAHEALTH INC DELAWARE | COM | 04685W103 | 1,255 | 11,933 | SH | | DFND | | 2,719 | 0 | 9,214 |
| ATKORE INTL GROUP INC COM | COM | 047649108 | 4,213 | 176,219 | SH | | DFND | | 44,711 | 0 | 131,508 |
| ATLASSIAN CORPORATION PLC COM USD0.1 CL A | COM | G06242104 | 12,087 | 501,941 | SH | | DFND | | 72,780 | 0 | 429,161 |
| AUTO TRADER GROUP PLC ORD GBP0.01 ISIN #GB00BVYVFW23 SEDOL #BVYV | COM | G06708104 | 9,867 | 1,952,363 | SH | | DFND | | 254,254 | 0 | 1,698,109 |
| AUTODESK INC COM | COM | 052769106 | 25,551 | 345,231 | SH | | DFND | | 20,214 | 0 | 325,017 |
| AXIS BANK GDR EACH REPR 1 INR10 REG S ISIN #US05462W1099 SEDOL # | COM | 05462W109 | 766 | 23,366 | SH | | DFND | | 22,275 | 0 | 1,091 |
| AXOGEN INC COM | COM | 05463X106 | 3,981 | 442,338 | SH | | DFND | | 84,917 | 0 | 357,421 |
| BAIDU INC SPONS ADR REPR 0.10 ORD CLS A | COM | 056752108 | 8,660 | 52,671 | SH | | DFND | | 11,876 | 0 | 40,795 |
| BANK OF THE OZARKS INC COM | COM | 063904106 | 2,381 | 45,271 | SH | | DFND | | 4,119 | 0 | 41,152 |
| BARNES &NOBLE INC COM | COM | 067774109 | 31 | 2,819 | SH | | DFND | | 540 | 0 | 2,279 |
| BELLATRIX EXPLORATION LTD COM ISIN #CA0783141017 SEDOL #B580BW5 | COM | 078314101 | 697 | 738,620 | SH | | DFND | | 109,351 | 0 | 629,269 |
| BERKLEY W R CORP | COM | 084423102 | 4,475 | 67,276 | SH | | DFND | | 16,957 | 0 | 50,319 |
| BERKSHIRE HATHAWAY INC DEL CL B NEW | COM | 084670702 | 33 | 200 | SH | | DFND | | 0 | 0 | 200 |
| BIOMARIN PHARMACEUTICAL INC | COM | 09061G101 | 20,199 | 243,836 | SH | | DFND | | 101,715 | 0 | 142,121 |
| BLACKLINE INC COM | COM | 09239B109 | 172 | 6,211 | SH | | DFND | | 3,285 | 0 | 2,926 |
| BMC STK HLDGS INC COM | COM | 05591B109 | 29,633 | 1,519,662 | SH | | DFND | | 181,882 | 0 | 1,337,780 |
| BOINGO WIRELESS INC COM USD0.0001 | COM | 09739C102 | 26,046 | 2,136,658 | SH | | DFND | | 328,482 | 0 | 1,808,176 |
| BOSTON SCIENTIFIC CORP | COM | 101137107 | 1,021 | 47,194 | SH | | DFND | | 20,722 | 0 | 26,472 |
| BOX INC CL A | COM | 10316T104 | 226 | 16,297 | SH | | DFND | | 2,161 | 0 | 14,136 |
| BRIGHTCOVE INC COM USD0.001 | COM | 10921T101 | 4,275 | 531,075 | SH | | DFND | | 99,361 | 0 | 431,714 |
| CARROLS RESTAURANT GROUP INC COM | COM | 14574X104 | 13,422 | 880,157 | SH | | DFND | | 80,358 | 0 | 799,799 |
| CATABASIS PHARMACEUTICALS INC COM | COM | 14875P107 | 81 | 22,445 | SH | | DFND | | 5,534 | 0 | 16,911 |
| CATAPULT GROUP INTL LTD ISIN #AU000000CAT9 SEDOL #BTL0Y76 | COM | Q2159P101 | 21,889 | 12,288,067 | SH | | DFND | | 2,746,676 | 0 | 9,541,391 |
| CAVIUM INC COM | COM | 14964U108 | 22,586 | 361,720 | SH | | DFND | | 25,907 | 0 | 335,813 |
| CBS CORP NEW CL B | COM | 124857202 | 1,881 | 29,560 | SH | | DFND | | 7,236 | 0 | 22,324 |
| CHARTER COMMUNICATIONS INC NEW CL A | COM | 16119P108 | 172 | 596 | SH | | DFND | | 26 | 0 | 570 |
| CHEGG INC COM USD0.001 | COM | 163092109 | 62 | 8,447 | SH | | DFND | | 4,402 | 0 | 4,045 |
| CHIPOTLE MEXICAN GRILL INC COM | COM | 169656105 | 74 | 195 | SH | | DFND | | 16 | 0 | 179 |
| CITIGROUP INC COM NEW | COM | 172967424 | 1,199 | 20,171 | SH | | DFND | | 5,263 | 0 | 14,908 |
| COGENT COMMUNICATION HLDGS INC COM NEW | COM | 19239V302 | 293 | 7,090 | SH | | DFND | | 667 | 0 | 6,423 |
| COMERICA INC | COM | 200340107 | 2,127 | 31,225 | SH | | DFND | | 66 | 0 | 31,159 |
| CONSTELLATION BRANDS INC CL A | COM | 21036P108 | 5,100 | 33,267 | SH | | DFND | | 836 | 0 | 32,431 |
| COSTAR GROUP INC COM | COM | 22160N109 | 15,122 | 80,227 | SH | | DFND | | 10,257 | 0 | 69,970 |
| COSTCO WHOLESALE CORP | COM | 22160K105 | 152 | 950 | SH | | DFND | | 26 | 0 | 924 |
| CTRIP.COM INTERNATIONAL LTD ADS EACH REP 0.125 ORD USD0.01 | COM | 22943F100 | 33 | 835 | SH | | DFND | | 145 | 0 | 690 |
| DEERE & COMPANY | COM | 244199105 | 10 | 100 | SH | | DFND | | 0 | 0 | 100 |
| DELTA AIR LINES INC DEL COM NEW | COM | 247361702 | 7,886 | 160,309 | SH | | DFND | | 4,618 | 0 | 155,691 |
| DEPOMED INC | COM | 249908104 | 814 | 45,162 | SH | | DFND | | 14,400 | 0 | 30,762 |
| DEXCOM INC | COM | 252131107 | 31,327 | 524,744 | SH | | DFND | | 144,353 | 0 | 380,391 |
| DIRTT ENVIRONMENTAL SOLUT LTD COM ISIN #CA25490H1064 SEDOL #BH13 | COM | 25490H106 | 49,056 | 10,492,255 | SH | | DFND | | 604,246 | 0 | 9,888,009 |
| DOMINOS PIZZA ENTERPRISES LIMITED NPV ISIN #AU000000DMP0 SEDOL # | COM | Q32503106 | 39,238 | 833,809 | SH | | DFND | | 243,681 | 0 | 590,128 |
| DXP ENTERPRISES INC NEW | COM | 233377407 | 1,783 | 51,330 | SH | | DFND | | 22,155 | 0 | 29,175 |
| E L F BEAUTY INC COM | COM | 26856L103 | 17,579 | 607,420 | SH | | DFND | | 226,235 | 0 | 381,185 |
| EBAY INC | COM | 278642103 | 161 | 5,408 | SH | | DFND | | 149 | 0 | 5,259 |
| ECO STIM ENERGY SOLUTIONS INC COM | COM | 27888D101 | 909 | 947,312 | SH | | DFND | | 70,475 | 0 | 876,837 |
| ECOSYNTHETIX INC COM ISIN #CA27923D1087 SEDOL #B4XBZ35 | COM | 27923D108 | 96 | 56,858 | SH | | DFND | | 4,804 | 0 | 52,054 |
| EDWARDS LIFESCIENCES CORP | COM | 28176E108 | 1,867 | 19,922 | SH | | DFND | | 4,376 | 0 | 15,546 |
| ELECTRONIC ARTS | COM | 285512109 | 26,513 | 336,624 | SH | | DFND | | 61,210 | 0 | 275,414 |
| ENPHASE ENERGY INC COM USD0.00001 | COM | 29355A107 | 38 | 37,723 | SH | | DFND | | 7,029 | 0 | 30,694 |
| ENZO BIOCHEM INC | COM | 294100102 | 5,718 | 823,953 | SH | | DFND | | 215,362 | 0 | 608,591 |
| EPAM SYS INC COM USD0.001 | COM | 29414B104 | 40,618 | 631,598 | SH | | DFND | | 35,059 | 0 | 596,539 |
| ESPERION THERAPEUTICS INC COM USD0.001 | COM | 29664W105 | 22 | 1,753 | SH | | DFND | | 204 | 0 | 1,549 |
| ETSY INC COM | COM | 29786A106 | 241 | 20,477 | SH | | DFND | | 4,980 | 0 | 15,497 |
| EVERBRIDGE INC COM | COM | 29978A104 | 9,278 | 502,870 | SH | | DFND | | 90,713 | 0 | 412,157 |
| EVOLENT HEALTH INC CL A | COM | 30050B101 | 4,873 | 329,234 | SH | | DFND | | 57,113 | 0 | 272,121 |
| EXACT SCIENCES CORP | COM | 30063P105 | 49,604 | 3,712,851 | SH | | DFND | | 830,945 | 0 | 2,881,906 |
| EXTRACTION OIL AND GAS INC COM | COM | 30227M105 | 12,362 | 616,843 | SH | | DFND | | 79,644 | 0 | 537,199 |
| FACEBOOK INC COM USD0.000006 CL A | COM | 30303M102 | 253,577 | 2,204,059 | SH | | DFND | | 588,514 | 0 | 1,615,545 |
| FAIRFAX INDIA HOLDINGS CORPORATION COM SUB VTG SHS ISIN #CA30389 | COM | 303897102 | 946 | 81,917 | SH | | DFND | | 31,660 | 0 | 50,257 |
| FARMER BROS CO COM | COM | 307675108 | 3,420 | 93,187 | SH | | DFND | | 21,645 | 0 | 71,542 |
| FEDERAL NATL MTG ASSN | COM | 313586109 | 246 | 63,147 | SH | | DFND | | 7,604 | 0 | 55,543 |
| FEVERTREE DRINKS PLC ORD GBP0.0025 ISIN #GB00BRJ9BJ26 SEDOL #BRJ | COM | G33929103 | 1,593 | 113,181 | SH | | DFND | | 74,199 | 0 | 38,982 |
| FIRST REP BK SAN FRANCISCO CAL COM | COM | 33616C100 | 42,682 | 463,232 | SH | | DFND | | 57,105 | 0 | 406,127 |
| FLEETCOR TECHNOLOGIES INC COM STK USD0.001 | COM | 339041105 | 10,874 | 76,835 | SH | | DFND | | 8,126 | 0 | 68,709 |
| FLEXION THERAPEUTICS INC COM | COM | 33938J106 | 83,289 | 4,379,002 | SH | | DFND | | 785,483 | 0 | 3,593,519 |
| FLIR SYS INC | COM | 302445101 | 23,582 | 651,609 | SH | | DFND | | 251,713 | 0 | 399,896 |
| FORTUNE BRANDS HOME & SECURITY INC USD0.01 | COM | 34964C106 | 63 | 1,180 | SH | | DFND | | 23 | 0 | 1,157 |
| FOSSIL GROUP INC COM | COM | 34988V106 | 720 | 27,843 | SH | | DFND | | 6,315 | 0 | 21,528 |
| FOUNDATION MEDICINE INC USD0.0001 | COM | 350465100 | 28,382 | 1,603,518 | SH | | DFND | | 495,906 | 0 | 1,107,612 |
| FOUR SEAS MERCANTILE HLDGS HKD0.10 ISIN #KYG365451049 SEDOL #634 | COM | G36545104 | 336 | 660,875 | SH | | DFND | | 506,000 | 0 | 154,875 |
| FRANCO NEVADA CORP COM ISIN #CA3518581051 SEDOL #B29NF31 | COM | 351858105 | 5,651 | 94,561 | SH | | DFND | | 2,715 | 0 | 91,846 |
| FREDDIE MAC | COM | 313400301 | 125 | 33,467 | SH | | DFND | | 6,768 | 0 | 26,699 |
| FULGENT GENETICS INC COM | COM | 359664109 | 96 | 8,334 | SH | | DFND | | 0 | 0 | 8,334 |
| GALAPAGOS NV NPV ISIN #BE0003818359 SEDOL #B07Q2V5 | COM | B44170106 | 20,458 | 318,283 | SH | | DFND | | 101,795 | 0 | 216,488 |
| GIGAMON INC COM USD0.0001 | COM | 37518B102 | 58,243 | 1,278,667 | SH | | DFND | | 139,288 | 0 | 1,139,379 |
| GILDAN ACTIVEWEAR INC COM ISIN #CA3759161035 SEDOL #2254645 | COM | 375916103 | 9,842 | 387,950 | SH | | DFND | | 38,399 | 0 | 349,551 |
| GILEAD SCIENCES INC | COM | 375558103 | 305 | 4,257 | SH | | DFND | | 817 | 0 | 3,440 |
| GLAUKOS CORP COM | COM | 377322102 | 52,621 | 1,534,129 | SH | | DFND | | 344,376 | 0 | 1,189,753 |
| GLOBANT SA USD1.20 | COM | L44385109 | 787 | 23,594 | SH | | DFND | | 14,769 | 0 | 8,825 |
| GODADDY INC CL A | COM | 380237107 | 8,409 | 240,595 | SH | | DFND | | 40,332 | 0 | 200,263 |
| GOLD STD VENTURES CORP COM ISIN #CA3807381049 SEDOL #B05J9S2 | COM | 380738104 | 2,444 | 1,147,444 | SH | | DFND | | 104,900 | 0 | 1,042,544 |
| GOLDEN MINERALS CO COM ISIN #US3811191069 SEDOL #B3K4M51 | COM | 381119106 | 29 | 49,784 | SH | | DFND | | 5,744 | 0 | 44,040 |
| GRACE W R & CO DEL NEW | COM | 38388F108 | 16,280 | 240,679 | SH | | DFND | | 37,758 | 0 | 202,921 |
| GREEN BRICK PARTNERS INC | COM | 392709101 | 3,488 | 347,032 | SH | | DFND | | 4,082 | 0 | 342,950 |
| GRUPO SUPERVIELLE S A SPONSORED ADR | COM | 40054A108 | 21,887 | 1,665,641 | SH | | DFND | | 162,141 | 0 | 1,503,500 |
| GTT COMMUNICATIONS INC COM USD0.0001 | COM | 362393100 | 55,825 | 1,941,730 | SH | | DFND | | 350,106 | 0 | 1,591,624 |
| GUIDEWIRE SOFTWARE INC COM USD0.0001 | COM | 40171V100 | 1,824 | 36,982 | SH | | DFND | | 8,071 | 0 | 28,911 |
| H &E EQUIPMENT SERVICES INC COM | COM | 404030108 | 2,848 | 122,509 | SH | | DFND | | 35,251 | 0 | 87,258 |
| HDFC BANK LTD ADS EACH REPR 3 INR10(MGT) | COM | 40415F101 | 35,261 | 581,090 | SH | | DFND | | 167,547 | 0 | 413,543 |
| HEALTHEQUITY INC COM | COM | 42226A107 | 3,567 | 88,033 | SH | | DFND | | 6,744 | 0 | 81,289 |
| HERC HLDGS INC COM | COM | 42704L104 | 110 | 2,742 | SH | | DFND | | 1,288 | 0 | 1,454 |
| HUBSPOT INC COM | COM | 443573100 | 71,833 | 1,528,352 | SH | | DFND | | 244,809 | 0 | 1,283,543 |
| HYPOPORT FINANCE AG NPV (REGD) ISIN #DE0005493365 SEDOL #B28XLF6 | COM | ZZC39YMG4 | 65 | 796 | SH | | DFND | | 158 | 0 | 638 |
| ICICI BANK LIMITED ADR EACH REPR 2 ORD INR10(SPON) | COM | 45104G104 | 99 | 13,257 | SH | | DFND | | 6,940 | 0 | 6,317 |
| IMPINJ INC COM | COM | 453204109 | 70,713 | 2,000,946 | SH | | DFND | | 262,153 | 0 | 1,738,793 |
| INCYTE CORP COM | COM | 45337C102 | 55,379 | 552,302 | SH | | DFND | | 229,113 | 0 | 323,189 |
| INFINERA CORPORATION COM | COM | 45667G103 | 72 | 8,437 | SH | | DFND | | 1,024 | 0 | 7,413 |
| INPHI CORPORATION COM USD0.001 | COM | 45772F107 | 8,424 | 188,794 | SH | | DFND | | 31,973 | 0 | 156,821 |
| INSULET CORP COM | COM | 45784P101 | 564 | 14,970 | SH | | DFND | | 6,046 | 0 | 8,924 |
| INTUITIVE SURGICAL INC COM NEW | COM | 46120E602 | 332 | 524 | SH | | DFND | | 110 | 0 | 414 |
| IRHYTHM TECHNOLOGIES INC COM | COM | 450056106 | 2,928 | 97,605 | SH | | DFND | | 11,493 | 0 | 86,112 |
| ITAU UNIBANCO HOLDINGS S.A. ADR EACH REPR 1 PRF NPV | COM | 465562106 | 3,289 | 319,894 | SH | | DFND | | 51,871 | 0 | 268,023 |
| JD COM INC SPONSORED ADR REPSTG COM CL A | COM | 47215P106 | 417 | 16,379 | SH | | DFND | | 3,087 | 0 | 13,292 |
| KANSAS CITY SOUTHERN COM | COM | 485170302 | 21,560 | 254,092 | SH | | DFND | | 23,333 | 0 | 230,759 |
| KB HOME COM | COM | 48666K109 | 7,134 | 451,235 | SH | | DFND | | 80,897 | 0 | 370,338 |
| KORNIT DIGITAL LTD ORD ILS0.01 | COM | M6372Q113 | 7,679 | 607,029 | SH | | DFND | | 44,819 | 0 | 562,210 |
| KRAFT HEINZ CO COM | COM | 500754106 | 87 | 993 | SH | | DFND | | 27 | 0 | 966 |
| LGI HOMES INC COM | COM | 50187T106 | 61,561 | 2,142,756 | SH | | DFND | | 391,959 | 0 | 1,750,797 |
| LHC GROUP INC COM | COM | 50187A107 | 1,006 | 22,008 | SH | | DFND | | 6,780 | 0 | 15,228 |
| LIBERTY MEDIA CORP DELAWARE COM A BRAVES GRP | COM | 531229706 | 4,406 | 215,038 | SH | | DFND | | 5,605 | 0 | 209,433 |
| LIBERTY MEDIA CORP DELAWARE COM C BRAVES GRP | COM | 531229888 | 5,560 | 270,027 | SH | | DFND | | 6,987 | 0 | 263,040 |
| LIVEPERSON INC | COM | 538146101 | 3,747 | 496,319 | SH | | DFND | | 13,895 | 0 | 482,424 |
| LULULEMON ATHLETICA INC COM | COM | 550021109 | 68 | 1,040 | SH | | DFND | | 227 | 0 | 813 |
| LUMBER LIQUIDATORS HLDGS INC COM | COM | 55003T107 | 9,528 | 605,314 | SH | | DFND | | 115,041 | 0 | 490,273 |
| LUMENTUM HLDGS INC COM | COM | 55024U109 | 65,854 | 1,703,849 | SH | | DFND | | 278,372 | 0 | 1,425,477 |
| MARTIN MARIETTA MATLS INC | COM | 573284106 | 66,725 | 301,202 | SH | | DFND | | 30,439 | 0 | 270,763 |
| MASONITE INTERNATIONAL CORP COM NPV | COM | 575385109 | 16,610 | 252,437 | SH | | DFND | | 42,469 | 0 | 209,968 |
| MASTERCARD INCORPORATED CL A | COM | 57636Q104 | 11,743 | 113,731 | SH | | DFND | | 23,097 | 0 | 90,634 |
| MCDONALDS CORP | COM | 580135101 | 46,236 | 379,857 | SH | | DFND | | 27,096 | 0 | 352,761 |
| MEG ENERGY CORP COM ISIN #CA5527041084 SEDOL #B4XF9J1 | COM | 552704108 | 100 | 14,580 | SH | | DFND | | 3,600 | 0 | 10,980 |
| MERCADOLIBRE INC | COM | 58733R102 | 3,693 | 23,650 | SH | | DFND | | 2,877 | 0 | 20,773 |
| METRO BANK PLC ORD GBP0.000001 ISIN #GB00BZ6STL67 SEDOL #BZ6STL6 | COM | G60640102 | 105,657 | 2,923,319 | SH | | DFND | | 547,886 | 0 | 2,375,433 |
| MICRON TECHNOLOGY | COM | 595112103 | 602 | 27,472 | SH | | DFND | | 11,112 | 0 | 16,360 |
| MICROSOFT CORP | COM | 594918104 | 7,785 | 125,284 | SH | | DFND | | 23,024 | 0 | 102,260 |
| MOBILEYE NV EUR0.01 | COM | N51488117 | 3,888 | 101,991 | SH | | DFND | | 9,250 | 0 | 92,741 |
| MOLSON COORS BREWING CO CL B | COM | 60871R209 | 174 | 1,787 | SH | | DFND | | 49 | 0 | 1,738 |
| MORRISON(WM.)SUPERMA KETS ORD GBP0.10 ISIN #GB0006043169 SEDOL # | COM | G62748119 | 285 | 100,031 | SH | | DFND | | 23,334 | 0 | 76,697 |
| NATERA INC COM | COM | 632307104 | 374 | 31,933 | SH | | DFND | | 13,808 | 0 | 18,125 |
| NETFLIX COM INC COM | COM | 64110L106 | 379,244 | 3,063,362 | SH | | DFND | | 674,842 | 0 | 2,388,520 |
| NEVRO CORP COM USD0.001 | COM | 64157F103 | 47 | 640 | SH | | DFND | | 105 | 0 | 535 |
| NEW HOME CO INC COM | COM | 645370107 | 378 | 32,241 | SH | | DFND | | 2,500 | 0 | 29,741 |
| NEW RELIC INC COM | COM | 64829B100 | 860 | 30,425 | SH | | DFND | | 5,494 | 0 | 24,931 |
| NINTENDO CO LTD ADR(8 CNV INTO 1 ORD)NPV | COM | 654445303 | 41,266 | 1,569,040 | SH | | DFND | | 321,952 | 0 | 1,247,088 |
| NINTENDO CO LTD NPV ISIN #JP3756600007 SEDOL #6639550 | COM | J51699106 | 608 | 2,892 | SH | | DFND | | 648 | 0 | 2,244 |
| NOBLE MIDSTREAM PARTNERS LP COM UNIT REPST | COM | 65506L105 | 50 | 1,376 | SH | | DFND | | 0 | 0 | 1,376 |
| NORTHERN DYNASTY MINS COM NPV ISIN #CA66510M2040 SEDOL #2637848 | COM | 66510M204 | 2,434 | 1,175,972 | SH | | DFND | | 52,042 | 0 | 1,123,930 |
| NOVELION THERAPEUTICS INC COM NPV(POST REV SPLT) ISIN #CA67001K2 | COM | 67001K202 | 2,191 | 260,190 | SH | | DFND | | 44,030 | 0 | 216,160 |
| NUTANIX INC CL A | COM | 67059N108 | 1,381 | 52,000 | SH | | DFND | | 9,412 | 0 | 42,588 |
| NUTRI SYS INC NEW COM | COM | 67069D108 | 4,472 | 129,050 | SH | | DFND | | 22,544 | 0 | 106,506 |
| NUVASIVE INC COM | COM | 670704105 | 2,037 | 30,247 | SH | | DFND | | 6,876 | 0 | 23,371 |
| NUVECTRA CORP COM | COM | 67075N108 | 4,095 | 814,055 | SH | | DFND | | 129,794 | 0 | 684,261 |
| NV5 GLOBAL INC COM | COM | 62945V109 | 6,201 | 185,644 | SH | | DFND | | 8,060 | 0 | 177,584 |
| NVIDIA CORP | COM | 67066G104 | 3,200 | 29,979 | SH | | DFND | | 3,179 | 0 | 26,800 |
| NXSTAGE MED INC COM | COM | 67072V103 | 150,701 | 5,749,761 | SH | | DFND | | 913,836 | 0 | 4,835,925 |
| OCADO GROUP PLC ORD GBP0.02 ISIN #GB00B3MBS747 SEDOL #B3MBS74 | COM | G6718L106 | 60,475 | 18,531,629 | SH | | DFND | | 3,361,508 | 0 | 15,170,121 |
| OCLARO INC COM NEW | COM | 67555N206 | 8,128 | 908,198 | SH | | DFND | | 158,545 | 0 | 749,653 |
| ORBITAL ATK INC COM | COM | 68557N103 | 88 | 1,002 | SH | | DFND | | 204 | 0 | 798 |
| PACIFIC BIOSCIENCES CALIFORNIA INC COM USD0.0001 | COM | 69404D108 | 4,520 | 1,189,449 | SH | | DFND | | 882,099 | 0 | 307,350 |
| PACIFIC ETHANOL INC COM PAR $.001 | COM | 69423U305 | 21 | 2,218 | SH | | DFND | | 646 | 0 | 1,572 |
| PACIRA PHARMACEUTICALS INC COM USD0.001 | COM | 695127100 | 39,609 | 1,226,278 | SH | | DFND | | 445,816 | 0 | 780,462 |
| PALO ALTO NETWORKS INC COM USD0.0001 | COM | 697435105 | 6,294 | 50,331 | SH | | DFND | | 9,892 | 0 | 40,439 |
| PANDORA MEDIA INC COM | COM | 698354107 | 179 | 13,764 | SH | | DFND | | 1,219 | 0 | 12,545 |
| PAYCOM SOFTWARE INC COM USD0.01 | COM | 70432V102 | 806 | 17,710 | SH | | DFND | | 6,825 | 0 | 10,885 |
| PDF SOLUTIONS INC | COM | 693282105 | 34,524 | 1,530,989 | SH | | DFND | | 136,819 | 0 | 1,394,170 |
| PENSKE AUTOMOTIVE GROUP INC | COM | 70959W103 | 4,213 | 81,260 | SH | | DFND | | 18,759 | 0 | 62,501 |
| POOL CORP COM | COM | 73278L105 | 46,175 | 442,548 | SH | | DFND | | 62,349 | 0 | 380,199 |
| PROOFPOINT INC COM USD0.0001 | COM | 743424103 | 6,719 | 95,101 | SH | | DFND | | 6,620 | 0 | 88,481 |
| PURE STORAGE INC CL A | COM | 74624M102 | 2,526 | 223,369 | SH | | DFND | | 31,212 | 0 | 192,157 |
| PURPLEBRICKS GROUP PLC ORD GBP0.01 ISIN #GB00BYV2MV74 SEDOL #BYV | COM | G7S98A108 | 14,461 | 8,300,108 | SH | | DFND | | 2,769,260 | 0 | 5,530,848 |
| Q2 HLDGS INC COM | COM | 74736L109 | 41,354 | 1,433,413 | SH | | DFND | | 321,348 | 0 | 1,112,065 |
| REAL IND INC COM | COM | 75601W104 | 87 | 14,193 | SH | | DFND | | 2,100 | 0 | 12,093 |
| RENAISSANCERE HOLDINGS LTD COM STK USD1 | COM | G7496G103 | 23 | 167 | SH | | DFND | | 0 | 0 | 167 |
| REPUBLIC FIRST BANCORP INC COM | COM | 760416107 | 58 | 6,977 | SH | | DFND | | 1,328 | 0 | 5,649 |
| RIGHTMOVE PLC WINTERHILL SHS ISIN #GB00B2987V85 SEDOL #B2987V8 | COM | G75657109 | 18,657 | 386,860 | SH | | DFND | | 49,003 | 0 | 337,857 |
| RINGCENTRAL INC-CLASS A | COM | 76680R206 | 71,969 | 3,493,641 | SH | | DFND | | 566,076 | 0 | 2,927,565 |
| SABRE CORP COM | COM | 78573M104 | 85 | 3,401 | SH | | DFND | | 51 | 0 | 3,350 |
| SAFETY INS GROUP INC | COM | 78648T100 | 1,007 | 13,670 | SH | | DFND | | 1,170 | 0 | 12,500 |
| SALESFORCE COM INC | COM | 79466L302 | 14,416 | 210,576 | SH | | DFND | | 42,429 | 0 | 168,147 |
| SAREPTA THERAPEUTICS INC COM | COM | 803607100 | 299 | 10,885 | SH | | DFND | | 3,459 | 0 | 7,426 |
| SCOUT24 AG NPV 144A ISIN #DE000A12DM80 SEDOL #BYT9340 | COM | D345XT105 | 79 | 2,170 | SH | | DFND | | 422 | 0 | 1,748 |
| SECTOR SPDR TR SHS BEN INT TECHNOLOGY | COM | 81369Y803 | 1,619 | 33,475 | SH | | DFND | | 8,106 | 0 | 25,369 |
| SENESTECH INC COM | COM | 81720R109 | 7,384 | 905,963 | SH | | DFND | | 26,261 | 0 | 879,702 |
| SERVICENOW INC COM USD0.001 | COM | 81762P102 | 10,896 | 146,573 | SH | | DFND | | 24,668 | 0 | 121,905 |
| SHAKE SHACK INC CL A | COM | 819047101 | 69,864 | 1,952,043 | SH | | DFND | | 479,784 | 0 | 1,472,259 |
| SHERWIN WILLIAMS CO | COM | 824348106 | 679 | 2,527 | SH | | DFND | | 75 | 0 | 2,452 |
| SHOPIFY INC NPV SUBORDINATED A ISIN #CA82509L1076 SEDOL #BX865C7 | COM | 82509L107 | 11,437 | 266,788 | SH | | DFND | | 51,696 | 0 | 215,092 |
| SIENTRA INC COM USD0.01 | COM | 82621J105 | 5,942 | 697,383 | SH | | DFND | | 99,476 | 0 | 597,907 |
| SIGNATURE BK NEW YORK N Y COM | COM | 82669G104 | 3,945 | 26,265 | SH | | DFND | | 4,692 | 0 | 21,573 |
| SILVER SPRING NETWORKS INC COM USD0.001 | COM | 82817Q103 | 5,472 | 411,126 | SH | | DFND | | 67,274 | 0 | 343,852 |
| SILVER WHEATON CORPORATION COM NPV ISIN #CA8283361076 SEDOL #B05 | COM | 828336107 | 1,896 | 98,148 | SH | | DFND | | 910 | 0 | 97,238 |
| SILVERCREST METALS INC COM NPV ISIN #CA8283631015 SEDOL #BYVY3D2 | COM | 828363101 | 1,366 | 776,249 | SH | | DFND | | 105,682 | 0 | 670,567 |
| SIRIUS XM HLDGS INC COM | COM | 82968B103 | 2,516 | 565,475 | SH | | DFND | | 79,803 | 0 | 485,672 |
| SITEONE LANDSCAPE SUPPLY INC COM | COM | 82982L103 | 11,553 | 332,655 | SH | | DFND | | 36,089 | 0 | 296,566 |
| SIX FLAGS ENTMT CORP NEW COM | COM | 83001A102 | 11,989 | 199,942 | SH | | DFND | | 64,280 | 0 | 135,662 |
| SPARK THERAPEUTICS INC COM | COM | 84652J103 | 345 | 6,908 | SH | | DFND | | 3,206 | 0 | 3,702 |
| SPIRIT AIRLS INC COM | COM | 848577102 | 39,999 | 691,309 | SH | | DFND | | 73,649 | 0 | 617,660 |
| SPLUNK INC COM USD0.001 | COM | 848637104 | 9,473 | 185,205 | SH | | DFND | | 35,328 | 0 | 149,877 |
| SQUARE INC CL A | COM | 852234103 | 2,275 | 166,928 | SH | | DFND | | 46,498 | 0 | 120,430 |
| SS&C TECHNOLOGIES HLDGS INC COM | COM | 78467J100 | 21,312 | 745,192 | SH | | DFND | | 119,814 | 0 | 625,378 |
| STARBUCKS CORP COM USD0.001 | COM | 855244109 | 2,606 | 46,942 | SH | | DFND | | 9,454 | 0 | 37,488 |
| STRAIGHT PATH COMMUNICATIONS INC COM USD0.01 CL B | COM | 862578101 | 20,843 | 614,662 | SH | | DFND | | 111,061 | 0 | 503,601 |
| SUMMIT MATLS INC CL A | COM | 86614U100 | 7,137 | 300,015 | SH | | DFND | | 5,691 | 0 | 294,324 |
| SUNRUN INC COM | COM | 86771W105 | 358 | 67,376 | SH | | DFND | | 6,332 | 0 | 61,044 |
| SVB FINL GROUP | COM | 78486Q101 | 2,980 | 17,362 | SH | | DFND | | 2,866 | 0 | 14,496 |
| T MOBILE US INC COM | COM | 872590104 | 285 | 4,959 | SH | | DFND | | 474 | 0 | 4,485 |
| TALEND SA ADR EACH REP 1 ORD SHS | COM | 874224207 | 957 | 43,113 | SH | | DFND | | 10,262 | 0 | 32,851 |
| TELADOC INC COM | COM | 87918A105 | 19 | 1,126 | SH | | DFND | | 193 | 0 | 933 |
| TENCENT HOLDINGS LIMITED HKD0.00002 ISIN #KYG875721634 SEDOL #BM | COM | G87572163 | 37,164 | 1,518,930 | SH | | DFND | | 410,443 | 0 | 1,108,487 |
| TESLA MOTORS INC COM USD0.001 | COM | 88160R101 | 151,360 | 708,316 | SH | | DFND | | 242,631 | 0 | 465,685 |
| THE TRADE DESK INC COM CL A | COM | 88339J105 | 414 | 14,961 | SH | | DFND | | 1 | 0 | 14,960 |
| THERAPEUTICSMD INC COM | COM | 88338N107 | 19,682 | 3,411,162 | SH | | DFND | | 1,187,880 | 0 | 2,223,282 |
| TIME INC NEW COM | COM | 887228104 | 37 | 2,055 | SH | | DFND | | 0 | 0 | 2,055 |
| TRACTOR SUPPLY CO | COM | 892356106 | 2,240 | 29,541 | SH | | DFND | | 7,608 | 0 | 21,933 |
| TRANSDIGM GROUP INC COM | COM | 893641100 | 10,466 | 42,037 | SH | | DFND | | 3,205 | 0 | 38,832 |
| TRIPADVISOR INC COM | COM | 896945201 | 45,259 | 976,039 | SH | | DFND | | 238,418 | 0 | 737,621 |
| TSO3 INC COM ISIN #CA8730151013 SEDOL #2798518 | COM | 873015101 | 11,618 | 5,505,503 | SH | | DFND | | 477,922 | 0 | 5,027,581 |
| TWITTER INC COM USD0.000005 | COM | 90184L102 | 109 | 6,673 | SH | | DFND | | 6,673 | 0 | 0 |
| ULTA SALON COSMETCS &FRAG INC COM | COM | 90384S303 | 75,188 | 294,924 | SH | | DFND | | 40,031 | 0 | 254,893 |
| UNDER ARMOUR INC CL C | COM | 904311206 | 13,529 | 537,502 | SH | | DFND | | 250,200 | 0 | 287,302 |
| UNDER ARMOUR INC COM STK USD0.000333 CLASS A | COM | 904311107 | 15,556 | 535,494 | SH | | DFND | | 248,842 | 0 | 286,652 |
| UNIVERSAL DISPLAY CORP | COM | 91347P105 | 186 | 3,299 | SH | | DFND | | 2,101 | 0 | 1,198 |
| VALIDUS HOLDING LTD COM STK USD0.175 | COM | G9319H102 | 5,959 | 108,332 | SH | | DFND | | 27,438 | 0 | 80,894 |
| VANECK VECTORS ETF TR GOLD MINERS ETF | COM | 92189F106 | 11,201 | 535,437 | SH | | DFND | | 17,175 | 0 | 518,262 |
| VCA INC COM STK | COM | 918194101 | 2,927 | 42,642 | SH | | DFND | | 8,298 | 0 | 34,344 |
| VEEVA SYS INC CL A COM | COM | 922475108 | 34,637 | 851,044 | SH | | DFND | | 238,094 | 0 | 612,950 |
| VIVENDI SA EUR5.50 ISIN #FR0000127771 SEDOL #4834777 | COM | F97982106 | 21,351 | 1,121,153 | SH | | DFND | | 75,423 | 0 | 1,045,730 |
| WEATHERFORD INTL PLC ORD SHS | COM | G48833100 | 551 | 110,498 | SH | | DFND | | 3,029 | 0 | 107,469 |
| WELLS FARGO &COMPANY COM USD1.666 | COM | 949746101 | 1,576 | 28,602 | SH | | DFND | | 4,445 | 0 | 24,157 |
| WORKDAY INC CL A | COM | 98138H101 | 5,700 | 86,244 | SH | | DFND | | 15,636 | 0 | 70,608 |
| XERO LIMITED NPV ISIN #NZXROE0001S2 SEDOL #B1Y43C7 | COM | Q98665104 | 5,739 | 470,316 | SH | | DFND | | 413,967 | 0 | 56,349 |
| XTREME DRILLING CORP ISIN #CA98419V1004 SEDOL #B7J8QB6 | COM | 98419V100 | 3,529 | 1,690,284 | SH | | DFND | | 160,207 | 0 | 1,530,077 |
| YOOX NET-A-PORTER GROUP NPV ISIN #IT0003540470 SEDOL #B4YC9W4 | COM | T9846S106 | 32,363 | 1,138,930 | SH | | DFND | | 71,430 | 0 | 1,067,500 |
| ZALANDO SE NPV ISIN #DE000ZAL1111 SEDOL #BQV0SV7 | COM | D98423102 | 263 | 6,893 | SH | | DFND | | 4,418 | 0 | 2,475 |
| ZAYO GROUP HLDGS INC COM | COM | 98919V105 | 49,533 | 1,507,380 | SH | | DFND | | 102,353 | 0 | 1,405,027 |
| ZELTIQ AESTHETICS INC COM | COM | 98933Q108 | 1,946 | 44,725 | SH | | DFND | | 13,899 | 0 | 30,826 |
| ZENDESK INC COM USD0.01 | COM | 98936J101 | 3,782 | 178,403 | SH | | DFND | | 33,935 | 0 | 144,468 |
| ZILLOW GROUP INC CL A | COM | 98954M101 | 20,035 | 549,663 | SH | | DFND | | 28,814 | 0 | 520,849 |
| ZILLOW GROUP INC CL C CAP STK | COM | 98954M200 | 42,281 | 1,159,344 | SH | | DFND | | 87,846 | 0 | 1,071,498 |
| ZOETIS INC COM USD0.01 CL A | COM | 98978V103 | 399 | 7,451 | SH | | DFND | | 237 | 0 | 7,214 |
