| COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 |
| | | VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY |
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | (x$1000) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
| 2U INC COM USD0.001 | COM | 90214J101 | 127,331 | 3,210,563 | SH | | DFND | | 780,157 | 0 | 2,430,406 |
| ABIOMED INC | COM | 003654100 | 1,866 | 14,901 | SH | | DFND | | 3,562 | 0 | 11,339 |
| ABRAXAS PETE CORP | COM | 003830106 | 838 | 415,071 | SH | | DFND | | 48,644 | 0 | 366,427 |
| ACACIA COMMUNICATIONS INC COM | COM | 00401C108 | 69,263 | 1,181,565 | SH | | DFND | | 238,248 | 0 | 943,317 |
| ACADIA HEALTHCARE COMPANY INC COM | COM | 00404A109 | 6,280 | 144,027 | SH | | DFND | | 4,136 | 0 | 139,891 |
| ACADIA PHARMACEUTICALS INC COM | COM | 004225108 | 308 | 8,946 | SH | | DFND | | 1,700 | 0 | 7,246 |
| ACCENTURE PLC CLS A USD0.0000225 | COM | G1151C101 | 786 | 6,553 | SH | | DFND | | 1,118 | 0 | 5,435 |
| ACTIVISION BLIZZARD INC COM | COM | 00507V109 | 89,258 | 1,790,171 | SH | | DFND | | 347,306 | 0 | 1,442,865 |
| ADESTO TECHNOLOGIES CORP COM | COM | 00687D101 | 6,943 | 1,673,088 | SH | | DFND | | 97,291 | 0 | 1,575,797 |
| ADIDAS AG NPV (REGD) ISIN #DE000A1EWWW0 SEDOL #4031976 | COM | D0066B185 | 26,735 | 140,247 | SH | | DFND | | 52,095 | 0 | 88,152 |
| ADOBE SYS INC | COM | 00724F101 | 66,822 | 513,499 | SH | | DFND | | 173,034 | 0 | 340,465 |
| ADVANCED DRAINAGE SYSTEM COM USD0.01 | COM | 00790R104 | 365 | 16,672 | SH | | DFND | | 494 | 0 | 16,178 |
| ADVERUM BIOTECHNOLOGIES INC COM | COM | 00773U108 | 123 | 45,425 | SH | | DFND | | 20,510 | 0 | 24,915 |
| ALIBABA GROUP HLDG LTD SPONSORED ADS | COM | 01609W102 | 36,117 | 334,945 | SH | | DFND | | 130,071 | 0 | 204,874 |
| ALIGN TECHNOLOGY INC COM | COM | 016255101 | 80,247 | 699,560 | SH | | DFND | | 86,147 | 0 | 613,413 |
| ALLEGIANT TRAVEL CO COM | COM | 01748X102 | 18,293 | 114,150 | SH | | DFND | | 8,119 | 0 | 106,031 |
| ALLERGAN PLC. COM USD0.0001 | COM | G0177J108 | 396 | 1,657 | SH | | DFND | | 46 | 0 | 1,611 |
| ALMOST FAMILY INC | COM | 020409108 | 18,095 | 372,329 | SH | | DFND | | 55,660 | 0 | 316,669 |
| ALNYLAM PHARMACEUTICALS INC | COM | 02043Q107 | 61,810 | 1,206,049 | SH | | DFND | | 292,798 | 0 | 913,251 |
| ALPHABET INC CAP STK CL A | COM | 02079K305 | 41,061 | 48,432 | SH | | DFND | | 4,790 | 0 | 43,642 |
| ALPHABET INC CAP STK CL C | COM | 02079K107 | 86,076 | 103,761 | SH | | DFND | | 19,408 | 0 | 84,353 |
| ALTERYX INC COM CL A | COM | 02156B103 | 66 | 4,229 | SH | | DFND | | 0 | 0 | 4,229 |
| AMAZON.COM INC | COM | 023135106 | 472,812 | 533,323 | SH | | DFND | | 198,513 | 0 | 334,810 |
| AMBER ROAD INC COM USD0.001 | COM | 02318Y108 | 568 | 73,562 | SH | | DFND | | 7,099 | 0 | 66,463 |
| AMEDISYS INC COM | COM | 023436108 | 42,492 | 831,707 | SH | | DFND | | 405,281 | 0 | 426,426 |
| AMERICAN INTL GROUP INC COM NEW | COM | 026874784 | 206 | 3,303 | SH | | DFND | | 91 | 0 | 3,212 |
| AMERICAN TOWER CORPORATION | COM | 03027X100 | 11,007 | 90,564 | SH | | DFND | | 8,593 | 0 | 81,971 |
| APACHE CORP | COM | 037411105 | 70,745 | 1,376,630 | SH | | DFND | | 153,457 | 0 | 1,223,173 |
| APPLE INC | COM | 037833100 | 3,826 | 26,630 | SH | | DFND | | 6,177 | 0 | 20,453 |
| APPLIED OPTOELECTRONICS INC COM | COM | 03823U102 | 15,142 | 269,673 | SH | | DFND | | 28,948 | 0 | 240,725 |
| ARISTA NETWORKS INC COM USD0.0001 | COM | 040413106 | 92,434 | 698,830 | SH | | DFND | | 36,231 | 0 | 662,599 |
| AT HOME GROUP INC COM | COM | 04650Y100 | 1,372 | 90,521 | SH | | DFND | | 7,172 | 0 | 83,349 |
| ATHENAHEALTH INC DELAWARE | COM | 04685W103 | 1,225 | 10,870 | SH | | DFND | | 2,194 | 0 | 8,676 |
| ATKORE INTL GROUP INC COM | COM | 047649108 | 6,551 | 249,266 | SH | | DFND | | 48,229 | 0 | 201,037 |
| ATLASSIAN CORPORATION PLC COM USD0.1 CL A | COM | G06242104 | 15,131 | 505,197 | SH | | DFND | | 65,068 | 0 | 440,129 |
| AUTO TRADER GROUP PLC ORD GBP0.01 ISIN #GB00BVYVFW23 SEDOL #BVYV | COM | G06708104 | 8,819 | 1,797,807 | SH | | DFND | | 239,579 | 0 | 1,558,228 |
| AUTODESK INC COM | COM | 052769106 | 70,063 | 810,263 | SH | | DFND | | 133,391 | 0 | 676,872 |
| AXIS BANK GDR EACH REPR 1 INR10 REG S ISIN #US05462W1099 SEDOL # | COM | 05462W109 | 640 | 16,871 | SH | | DFND | | 16,275 | 0 | 596 |
| AXOGEN INC COM | COM | 05463X106 | 5,847 | 559,516 | SH | | DFND | | 120,867 | 0 | 438,649 |
| BAIDU INC SPONS ADR REPR 0.10 ORD CLS A | COM | 056752108 | 8,944 | 51,841 | SH | | DFND | | 11,641 | 0 | 40,200 |
| BANK OF THE OZARKS INC COM | COM | 063904106 | 1,778 | 34,178 | SH | | DFND | | 2,683 | 0 | 31,495 |
| BASIC ENERGY SVCS INC NEW COM NEW | COM | 06985P209 | 7,119 | 213,403 | SH | | DFND | | 13,681 | 0 | 199,722 |
| BELLATRIX EXPLORATION LTD COM ISIN #CA0783141017 SEDOL #B580BW5 | COM | 078314101 | 509 | 640,749 | SH | | DFND | | 109,351 | 0 | 531,398 |
| BERKLEY W R CORP | COM | 084423102 | 4,778 | 67,655 | SH | | DFND | | 17,947 | 0 | 49,708 |
| BERKSHIRE HATHAWAY INC DEL CL B NEW | COM | 084670702 | 33 | 200 | SH | | DFND | | 0 | 0 | 200 |
| BIOSCRIP INC | COM | 09069N108 | 7,422 | 4,365,726 | SH | | DFND | | 853,321 | 0 | 3,512,405 |
| BLACKLINE INC COM | COM | 09239B109 | 183 | 6,154 | SH | | DFND | | 3,285 | 0 | 2,869 |
| BMC STK HLDGS INC COM | COM | 05591B109 | 27,994 | 1,238,673 | SH | | DFND | | 144,780 | 0 | 1,093,893 |
| BOINGO WIRELESS INC COM USD0.0001 | COM | 09739C102 | 26,363 | 2,029,475 | SH | | DFND | | 316,992 | 0 | 1,712,483 |
| BOSTON SCIENTIFIC CORP | COM | 101137107 | 1,171 | 47,076 | SH | | DFND | | 20,722 | 0 | 26,354 |
| BOX INC CL A | COM | 10316T104 | 266 | 16,315 | SH | | DFND | | 2,161 | 0 | 14,154 |
| BRIGHTCOVE INC COM USD0.001 | COM | 10921T101 | 4,665 | 524,204 | SH | | DFND | | 99,361 | 0 | 424,843 |
| C S X CORP | COM | 126408103 | 3,058 | 65,700 | SH | | DFND | | 11,931 | 0 | 53,769 |
| C&J ENERGY SVCS INC NEW COM | COM | 12674R100 | 7,779 | 228,468 | SH | | DFND | | 42,317 | 0 | 186,151 |
| CAESARS ENTMT CORP COM | COM | 127686103 | 2,754 | 288,385 | SH | | DFND | | 47,710 | 0 | 240,675 |
| CANADA GOOSE HOLDINGS INC COM NPV SUB VTNG SHS ISIN #CA135086106 | COM | 135086106 | 650 | 40,755 | SH | | DFND | | 481 | 0 | 40,274 |
| CARDIOVASCULAR SYS INC DEL COM | COM | 141619106 | 1,828 | 64,664 | SH | | DFND | | 13,801 | 0 | 50,863 |
| CARROLS RESTAURANT GROUP INC COM | COM | 14574X104 | 12,201 | 862,233 | SH | | DFND | | 80,358 | 0 | 781,875 |
| CATAPULT GROUP INTL LTD ISIN #AU000000CAT9 SEDOL #BTL0Y76 | COM | Q2159P101 | 18,168 | 10,584,823 | SH | | DFND | | 2,499,895 | 0 | 8,084,928 |
| CAVIUM INC COM | COM | 14964U108 | 45,004 | 628,020 | SH | | DFND | | 37,968 | 0 | 590,052 |
| CBS CORP NEW CL B | COM | 124857202 | 1,942 | 27,994 | SH | | DFND | | 5,616 | 0 | 22,378 |
| CHARTER COMMUNICATIONS INC NEW CL A | COM | 16119P108 | 195 | 596 | SH | | DFND | | 26 | 0 | 570 |
| CHIPOTLE MEXICAN GRILL INC COM | COM | 169656105 | 17 | 39 | SH | | DFND | | 11 | 0 | 28 |
| CITIGROUP INC COM NEW | COM | 172967424 | 4,011 | 67,053 | SH | | DFND | | 11,376 | 0 | 55,677 |
| COGENT COMMUNICATION HLDGS INC COM NEW | COM | 19239V302 | 308 | 7,148 | SH | | DFND | | 667 | 0 | 6,481 |
| COGNEX CORP COM | COM | 192422103 | 25,794 | 307,255 | SH | | DFND | | 85,699 | 0 | 221,556 |
| CONSTELLATION BRANDS INC CL A | COM | 21036P108 | 8,384 | 51,729 | SH | | DFND | | 4,650 | 0 | 47,079 |
| COSTAR GROUP INC COM | COM | 22160N109 | 14,566 | 70,292 | SH | | DFND | | 10,207 | 0 | 60,085 |
| COSTCO WHOLESALE CORP | COM | 22160K105 | 163 | 972 | SH | | DFND | | 26 | 0 | 946 |
| CRIMSON WINE GROUP COM USD0.01 | COM | 22662X100 | 203 | 20,297 | SH | | DFND | | 525 | 0 | 19,772 |
| CTRIP.COM INTERNATIONAL LTD ADS EACH REP 0.125 ORD USD0.01 | COM | 22943F100 | 41 | 835 | SH | | DFND | | 145 | 0 | 690 |
| DECKERS OUTDOOR CORP COM | COM | 243537107 | 505 | 8,447 | SH | | DFND | | 3,994 | 0 | 4,453 |
| DEERE & COMPANY | COM | 244199105 | 11 | 100 | SH | | DFND | | 0 | 0 | 100 |
| DELTA AIR LINES INC DEL COM NEW | COM | 247361702 | 7,134 | 155,225 | SH | | DFND | | 4,627 | 0 | 150,598 |
| DEXCOM INC | COM | 252131107 | 38,379 | 452,955 | SH | | DFND | | 143,864 | 0 | 309,091 |
| DIRTT ENVIRONMENTAL SOLUT LTD COM ISIN #CA25490H1064 SEDOL #BH13 | COM | 25490H106 | 52,311 | 9,980,713 | SH | | DFND | | 604,663 | 0 | 9,376,050 |
| DOMINOS PIZZA ENTERPRISES LIMITED NPV ISIN #AU000000DMP0 SEDOL # | COM | Q32503106 | 36,512 | 823,512 | SH | | DFND | | 246,146 | 0 | 577,366 |
| DXP ENTERPRISES INC NEW | COM | 233377407 | 903 | 23,848 | SH | | DFND | | 21,962 | 0 | 1,886 |
| E L F BEAUTY INC COM | COM | 26856L103 | 22,503 | 781,366 | SH | | DFND | | 282,096 | 0 | 499,270 |
| ECO STIM ENERGY SOLUTIONS INC COM | COM | 27888D101 | 992 | 847,670 | SH | | DFND | | 70,475 | 0 | 777,195 |
| ECOSYNTHETIX INC COM ISIN #CA27923D1087 SEDOL #B4XBZ35 | COM | 27923D108 | 110 | 62,312 | SH | | DFND | | 4,804 | 0 | 57,508 |
| ELBIT SYSTEMS LTD ISIN #IL0010811243 SEDOL #6308913 | COM | M3760D101 | 31,500 | 277,165 | SH | | DFND | | 120,364 | 0 | 156,801 |
| ELECTRONIC ARTS | COM | 285512109 | 29,529 | 329,858 | SH | | DFND | | 61,210 | 0 | 268,648 |
| ENPHASE ENERGY INC COM USD0.00001 | COM | 29355A107 | 1,231 | 898,485 | SH | | DFND | | 41,929 | 0 | 856,556 |
| ENZO BIOCHEM INC | COM | 294100102 | 6,958 | 831,354 | SH | | DFND | | 215,317 | 0 | 616,037 |
| EPAM SYS INC COM USD0.001 | COM | 29414B104 | 46,699 | 618,362 | SH | | DFND | | 35,128 | 0 | 583,234 |
| ESPERION THERAPEUTICS INC COM USD0.001 | COM | 29664W105 | 61 | 1,740 | SH | | DFND | | 204 | 0 | 1,536 |
| ETSY INC COM | COM | 29786A106 | 175 | 16,442 | SH | | DFND | | 4,210 | 0 | 12,232 |
| EVERBRIDGE INC COM | COM | 29978A104 | 12,912 | 628,926 | SH | | DFND | | 100,023 | 0 | 528,903 |
| EVOLENT HEALTH INC CL A | COM | 30050B101 | 5,833 | 261,566 | SH | | DFND | | 51,738 | 0 | 209,828 |
| EXACT SCIENCES CORP | COM | 30063P105 | 75,296 | 3,187,795 | SH | | DFND | | 632,528 | 0 | 2,555,267 |
| EXTRACTION OIL AND GAS INC COM | COM | 30227M105 | 11,101 | 598,425 | SH | | DFND | | 79,644 | 0 | 518,781 |
| FACEBOOK INC COM USD0.000006 CL A | COM | 30303M102 | 300,523 | 2,115,617 | SH | | DFND | | 580,171 | 0 | 1,535,446 |
| FAIRFAX INDIA HOLDINGS CORPORATION COM SUB VTG SHS ISIN #CA30389 | COM | 303897102 | 532 | 40,285 | SH | | DFND | | 31,340 | 0 | 8,945 |
| FARMER BROS CO COM | COM | 307675108 | 3,271 | 92,540 | SH | | DFND | | 21,645 | 0 | 70,895 |
| FB FINL CORP COM | COM | 30257X104 | 349 | 9,877 | SH | | DFND | | 4,239 | 0 | 5,638 |
| FEVERTREE DRINKS PLC ORD GBP0.0025 ISIN #GB00BRJ9BJ26 SEDOL #BRJ | COM | G33929103 | 1,023 | 54,380 | SH | | DFND | | 29,742 | 0 | 24,638 |
| FIRST REP BK SAN FRANCISCO CAL COM | COM | 33616C100 | 33,212 | 354,036 | SH | | DFND | | 49,122 | 0 | 304,914 |
| FLEXION THERAPEUTICS INC COM | COM | 33938J106 | 115,294 | 4,284,412 | SH | | DFND | | 784,340 | 0 | 3,500,072 |
| FLIR SYS INC | COM | 302445101 | 23,825 | 656,698 | SH | | DFND | | 257,438 | 0 | 399,260 |
| FORTUNE BRANDS HOME & SECURITY INC USD0.01 | COM | 34964C106 | 72 | 1,180 | SH | | DFND | | 23 | 0 | 1,157 |
| FOUNDATION MEDICINE INC USD0.0001 | COM | 350465100 | 51,950 | 1,610,865 | SH | | DFND | | 496,053 | 0 | 1,114,812 |
| FRANCO NEVADA CORP COM ISIN #CA3518581051 SEDOL #B29NF31 | COM | 351858105 | 5,958 | 90,954 | SH | | DFND | | 2,715 | 0 | 88,239 |
| FULGENT GENETICS INC COM | COM | 359664109 | 42 | 3,851 | SH | | DFND | | 0 | 0 | 3,851 |
| GALAPAGOS NV NPV ISIN #BE0003818359 SEDOL #B07Q2V5 | COM | B44170106 | 27,830 | 318,950 | SH | | DFND | | 101,795 | 0 | 217,155 |
| GEOPARK LIMITED COM USD0.001 | COM | G38327105 | 1,907 | 265,573 | SH | | DFND | | 6,403 | 0 | 259,170 |
| GIGAMON INC COM USD0.0001 | COM | 37518B102 | 33,777 | 950,113 | SH | | DFND | | 85,415 | 0 | 864,698 |
| GILDAN ACTIVEWEAR INC COM ISIN #CA3759161035 SEDOL #2254645 | COM | 375916103 | 9,560 | 353,541 | SH | | DFND | | 38,295 | 0 | 315,246 |
| GILEAD SCIENCES INC | COM | 375558103 | 288 | 4,240 | SH | | DFND | | 817 | 0 | 3,423 |
| GLAUKOS CORP COM | COM | 377322102 | 76,761 | 1,496,311 | SH | | DFND | | 336,826 | 0 | 1,159,485 |
| GLOBAL BLOOD THERAPEUTICS INC COM | COM | 37890U108 | 345 | 9,350 | SH | | DFND | | 3,527 | 0 | 5,823 |
| GLOBANT SA USD1.20 | COM | L44385109 | 824 | 22,650 | SH | | DFND | | 14,769 | 0 | 7,881 |
| GODADDY INC CL A | COM | 380237107 | 5,562 | 146,751 | SH | | DFND | | 24,157 | 0 | 122,594 |
| GOLAR LNG LIMITED COM STK USD1.00 | COM | G9456A100 | 9,112 | 326,246 | SH | | DFND | | 26,955 | 0 | 299,291 |
| GOLD STD VENTURES CORP COM ISIN #CA3807381049 SEDOL #B05J9S2 | COM | 380738104 | 2,271 | 1,051,478 | SH | | DFND | | 104,900 | 0 | 946,578 |
| GOLDEN MINERALS CO COM ISIN #US3811191069 SEDOL #B3K4M51 | COM | 381119106 | 31 | 49,704 | SH | | DFND | | 5,744 | 0 | 43,960 |
| GRACE W R & CO DEL NEW | COM | 38388F108 | 16,622 | 238,447 | SH | | DFND | | 39,293 | 0 | 199,154 |
| GREEN BRICK PARTNERS INC | COM | 392709101 | 3,219 | 323,532 | SH | | DFND | | 4,082 | 0 | 319,450 |
| GRUPO FINANCIERO GALICIA SA ADR EACH REPR 10 CLASS B ARS1 LVL11 | COM | 399909100 | 107 | 2,819 | SH | | DFND | | 540 | 0 | 2,279 |
| GTT COMMUNICATIONS INC COM USD0.0001 | COM | 362393100 | 46,920 | 1,926,918 | SH | | DFND | | 350,925 | 0 | 1,575,993 |
| GUIDEWIRE SOFTWARE INC COM USD0.0001 | COM | 40171V100 | 2,033 | 36,099 | SH | | DFND | | 8,071 | 0 | 28,028 |
| H &E EQUIPMENT SERVICES INC COM | COM | 404030108 | 2,258 | 92,092 | SH | | DFND | | 13,483 | 0 | 78,609 |
| HDFC BANK LTD ADS EACH REPR 3 INR10(MGT) | COM | 40415F101 | 43,133 | 573,429 | SH | | DFND | | 167,801 | 0 | 405,628 |
| HEALTHEQUITY INC COM | COM | 42226A107 | 3,642 | 85,789 | SH | | DFND | | 6,628 | 0 | 79,161 |
| HERC HLDGS INC COM | COM | 42704L104 | 414 | 8,460 | SH | | DFND | | 5,010 | 0 | 3,450 |
| HUBSPOT INC COM | COM | 443573100 | 87,752 | 1,449,245 | SH | | DFND | | 238,130 | 0 | 1,211,115 |
| ICICI BANK LIMITED ADR EACH REPR 2 ORD INR10(SPON) | COM | 45104G104 | 120 | 13,956 | SH | | DFND | | 9,047 | 0 | 4,909 |
| ILLUMINA INC COM | COM | 452327109 | 455 | 2,666 | SH | | DFND | | 530 | 0 | 2,136 |
| IMPINJ INC COM | COM | 453204109 | 59,380 | 1,961,678 | SH | | DFND | | 259,794 | 0 | 1,701,884 |
| INCYTE CORP COM | COM | 45337C102 | 73,509 | 549,928 | SH | | DFND | | 229,098 | 0 | 320,830 |
| INFINERA CORPORATION COM | COM | 45667G103 | 86 | 8,395 | SH | | DFND | | 1,024 | 0 | 7,371 |
| INPHI CORPORATION COM USD0.001 | COM | 45772F107 | 8,145 | 166,845 | SH | | DFND | | 29,198 | 0 | 137,647 |
| INSULET CORP COM | COM | 45784P101 | 644 | 14,937 | SH | | DFND | | 6,046 | 0 | 8,891 |
| INTUITIVE SURGICAL INC COM NEW | COM | 46120E602 | 55,860 | 72,880 | SH | | DFND | | 5,109 | 0 | 67,771 |
| IRHYTHM TECHNOLOGIES INC COM | COM | 450056106 | 3,659 | 97,305 | SH | | DFND | | 11,493 | 0 | 85,812 |
| ITAU UNIBANCO HOLDINGS S.A. ADR EACH REPR 1 PRF NPV | COM | 465562106 | 3,756 | 311,195 | SH | | DFND | | 51,871 | 0 | 259,324 |
| J JILL INC COM | COM | 46620W102 | 845 | 59,909 | SH | | DFND | | 3,498 | 0 | 56,411 |
| JD COM INC SPONSORED ADR REPSTG COM CL A | COM | 47215P106 | 352 | 11,329 | SH | | DFND | | 2,958 | 0 | 8,371 |
| JELD-WEN HLDG INC COM | COM | 47580P103 | 2,330 | 70,943 | SH | | DFND | | 4,220 | 0 | 66,723 |
| KANSAS CITY SOUTHERN COM | COM | 485170302 | 6,827 | 79,603 | SH | | DFND | | 7,720 | 0 | 71,883 |
| KB HOME COM | COM | 48666K109 | 14,605 | 734,681 | SH | | DFND | | 83,212 | 0 | 651,469 |
| KITE PHARMA INC COM | COM | 49803L109 | 810 | 10,316 | SH | | DFND | | 3,724 | 0 | 6,592 |
| KORNIT DIGITAL LTD ORD ILS0.01 | COM | M6372Q113 | 31,859 | 1,668,032 | SH | | DFND | | 425,396 | 0 | 1,242,636 |
| KRAFT HEINZ CO COM | COM | 500754106 | 90 | 993 | SH | | DFND | | 27 | 0 | 966 |
| LGI HOMES INC COM | COM | 50187T106 | 70,730 | 2,085,828 | SH | | DFND | | 379,651 | 0 | 1,706,177 |
| LHC GROUP INC COM | COM | 50187A107 | 1,565 | 29,043 | SH | | DFND | | 8,625 | 0 | 20,418 |
| LIBERTY MEDIA CORP DELAWARE COM A BRAVES GRP | COM | 531229706 | 4,877 | 203,713 | SH | | DFND | | 5,605 | 0 | 198,108 |
| LIBERTY MEDIA CORP DELAWARE COM C BRAVES GRP | COM | 531229888 | 6,399 | 270,560 | SH | | DFND | | 7,181 | 0 | 263,379 |
| LIBERTY MEDIA CORP DELAWARE COM SER C FRMLA | COM | 531229854 | 110 | 3,231 | SH | | DFND | | 87 | 0 | 3,144 |
| LIVEPERSON INC | COM | 538146101 | 8,043 | 1,174,111 | SH | | DFND | | 34,927 | 0 | 1,139,184 |
| LUMBER LIQUIDATORS HLDGS INC COM | COM | 55003T107 | 38,643 | 1,841,021 | SH | | DFND | | 659,980 | 0 | 1,181,041 |
| LUMENTUM HLDGS INC COM | COM | 55024U109 | 90,809 | 1,702,138 | SH | | DFND | | 325,935 | 0 | 1,376,203 |
| MADISON SQUARE GARDEN CO NEW CL A | COM | 55825T103 | 3,444 | 17,246 | SH | | DFND | | 3,030 | 0 | 14,216 |
| MAKEMYTRIP LTD USD0.0005 | COM | V5633W109 | 4,213 | 121,757 | SH | | DFND | | 25,269 | 0 | 96,488 |
| MARTIN MARIETTA MATLS INC | COM | 573284106 | 63,567 | 291,260 | SH | | DFND | | 32,760 | 0 | 258,500 |
| MASONITE INTERNATIONAL CORP COM NPV | COM | 575385109 | 17,146 | 216,352 | SH | | DFND | | 37,474 | 0 | 178,878 |
| MASTERCARD INCORPORATED CL A | COM | 57636Q104 | 12,475 | 110,916 | SH | | DFND | | 21,147 | 0 | 89,769 |
| MCDONALDS CORP | COM | 580135101 | 47,943 | 369,901 | SH | | DFND | | 25,808 | 0 | 344,093 |
| MEG ENERGY CORP COM ISIN #CA5527041084 SEDOL #B4XF9J1 | COM | 552704108 | 72 | 14,200 | SH | | DFND | | 3,600 | 0 | 10,600 |
| MERCADOLIBRE INC | COM | 58733R102 | 4,783 | 22,617 | SH | | DFND | | 2,751 | 0 | 19,866 |
| MERCURY SYS INC COM | COM | 589378108 | 35,579 | 911,118 | SH | | DFND | | 267,005 | 0 | 644,113 |
| METRO BANK PLC ORD GBP0.000001 ISIN #GB00BZ6STL67 SEDOL #BZ6STL6 | COM | G60640102 | 125,472 | 3,083,631 | SH | | DFND | | 607,895 | 0 | 2,475,736 |
| MICRON TECHNOLOGY | COM | 595112103 | 793 | 27,433 | SH | | DFND | | 11,112 | 0 | 16,321 |
| MICROSOFT CORP | COM | 594918104 | 10,212 | 155,059 | SH | | DFND | | 32,008 | 0 | 123,051 |
| MOBILEYE NV EUR0.01 | COM | N51488117 | 5,797 | 94,420 | SH | | DFND | | 8,496 | 0 | 85,924 |
| MOLSON COORS BREWING CO CL B | COM | 60871R209 | 241 | 2,513 | SH | | DFND | | 64 | 0 | 2,449 |
| MONOLITHIC PWR SYS INC COM | COM | 609839105 | 10,025 | 108,847 | SH | | DFND | | 10,624 | 0 | 98,223 |
| MORRISON(WM.)SUPERMA KETS ORD GBP0.10 ISIN #GB0006043169 SEDOL # | COM | G62748119 | 299 | 99,739 | SH | | DFND | | 23,334 | 0 | 76,405 |
| MULESOFT INC CL A | COM | 625207105 | 30,691 | 1,261,452 | SH | | DFND | | 367,788 | 0 | 893,664 |
| NETFLIX COM INC COM | COM | 64110L106 | 391,156 | 2,646,345 | SH | | DFND | | 611,431 | 0 | 2,034,914 |
| NEVRO CORP COM USD0.001 | COM | 64157F103 | 14,931 | 159,354 | SH | | DFND | | 4,769 | 0 | 154,585 |
| NEW HOME CO INC COM | COM | 645370107 | 332 | 31,707 | SH | | DFND | | 2,500 | 0 | 29,207 |
| NEW RELIC INC COM | COM | 64829B100 | 5,349 | 144,282 | SH | | DFND | | 24,732 | 0 | 119,550 |
| NINTENDO CO LTD ADR(8 CNV INTO 1 ORD)NPV | COM | 654445303 | 23,070 | 796,035 | SH | | DFND | | 75,582 | 0 | 720,453 |
| NINTENDO CO LTD NPV ISIN #JP3756600007 SEDOL #6639550 | COM | J51699106 | 672 | 2,897 | SH | | DFND | | 648 | 0 | 2,249 |
| NOBLE MIDSTREAM PARTNERS LP COM UNIT REPST | COM | 65506L105 | 69 | 1,331 | SH | | DFND | | 0 | 0 | 1,331 |
| NORTHERN DYNASTY MINS COM NPV ISIN #CA66510M2040 SEDOL #2637848 | COM | 66510M204 | 1,464 | 1,024,013 | SH | | DFND | | 52,042 | 0 | 971,971 |
| NOVELION THERAPEUTICS INC COM NPV(POST REV SPLT) ISIN #CA67001K2 | COM | 67001K202 | 3,561 | 331,599 | SH | | DFND | | 66,226 | 0 | 265,373 |
| NUTANIX INC CL A | COM | 67059N108 | 781 | 41,598 | SH | | DFND | | 9,412 | 0 | 32,186 |
| NUTRI SYS INC NEW COM | COM | 67069D108 | 11,076 | 199,564 | SH | | DFND | | 34,019 | 0 | 165,545 |
| NUVASIVE INC COM | COM | 670704105 | 2,155 | 28,863 | SH | | DFND | | 5,436 | 0 | 23,427 |
| NUVECTRA CORP COM | COM | 67075N108 | 5,791 | 847,851 | SH | | DFND | | 139,814 | 0 | 708,037 |
| NV5 GLOBAL INC COM | COM | 62945V109 | 6,766 | 179,943 | SH | | DFND | | 8,060 | 0 | 171,883 |
| NVIDIA CORP | COM | 67066G104 | 7,329 | 67,284 | SH | | DFND | | 29,866 | 0 | 37,418 |
| NXSTAGE MED INC COM | COM | 67072V103 | 132,960 | 4,955,630 | SH | | DFND | | 893,621 | 0 | 4,062,009 |
| OCADO GROUP PLC ORD GBP0.02 ISIN #GB00B3MBS747 SEDOL #B3MBS74 | COM | G6718L106 | 56,728 | 18,824,246 | SH | | DFND | | 3,508,358 | 0 | 15,315,888 |
| OCEANAGOLD CORPORATION COM ISIN #CA6752221037 SEDOL #B1Z7L21 | COM | 675222103 | 2,790 | 944,550 | SH | | DFND | | 27,045 | 0 | 917,505 |
| OCLARO INC COM NEW | COM | 67555N206 | 7,029 | 715,779 | SH | | DFND | | 130,366 | 0 | 585,413 |
| OOMA INC COM | COM | 683416101 | 3,510 | 352,798 | SH | | DFND | | 55,084 | 0 | 297,714 |
| ORBITAL ATK INC COM | COM | 68557N103 | 102 | 1,037 | SH | | DFND | | 204 | 0 | 833 |
| PACIFIC BIOSCIENCES CALIFORNIA INC COM USD0.0001 | COM | 69404D108 | 18,710 | 3,618,977 | SH | | DFND | | 911,603 | 0 | 2,707,374 |
| PACIFIC ETHANOL INC COM PAR $.001 | COM | 69423U305 | 15 | 2,218 | SH | | DFND | | 646 | 0 | 1,572 |
| PACIRA PHARMACEUTICALS INC COM USD0.001 | COM | 695127100 | 55,852 | 1,224,814 | SH | | DFND | | 448,776 | 0 | 776,038 |
| PANDORA MEDIA INC COM | COM | 698354107 | 160 | 13,525 | SH | | DFND | | 1,219 | 0 | 12,306 |
| PDF SOLUTIONS INC | COM | 693282105 | 36,824 | 1,627,953 | SH | | DFND | | 166,169 | 0 | 1,461,784 |
| PENSKE AUTOMOTIVE GROUP INC | COM | 70959W103 | 3,757 | 80,269 | SH | | DFND | | 18,724 | 0 | 61,545 |
| POOL CORP COM | COM | 73278L105 | 52,176 | 437,245 | SH | | DFND | | 65,235 | 0 | 372,010 |
| PROOFPOINT INC COM USD0.0001 | COM | 743424103 | 6,883 | 92,564 | SH | | DFND | | 6,048 | 0 | 86,516 |
| PTC INC COM | COM | 69370C100 | 132 | 2,519 | SH | | DFND | | 1,560 | 0 | 959 |
| PURE STORAGE INC CL A | COM | 74624M102 | 1,922 | 195,524 | SH | | DFND | | 20,043 | 0 | 175,481 |
| PURPLEBRICKS GROUP PLC ORD GBP0.01 ISIN #GB00BYV2MV74 SEDOL #BYV | COM | G7S98A108 | 24,850 | 6,997,531 | SH | | DFND | | 2,234,657 | 0 | 4,762,874 |
| Q2 HLDGS INC COM | COM | 74736L109 | 45,602 | 1,308,518 | SH | | DFND | | 236,401 | 0 | 1,072,117 |
| RENAISSANCERE HOLDINGS LTD COM STK USD1 | COM | G7496G103 | 24 | 167 | SH | | DFND | | 0 | 0 | 167 |
| REPUBLIC FIRST BANCORP INC COM | COM | 760416107 | 1,540 | 185,552 | SH | | DFND | | 4,553 | 0 | 180,999 |
| RIGHTMOVE PLC WINTERHILL SHS ISIN #GB00B2987V85 SEDOL #B2987V8 | COM | G75657109 | 18,859 | 378,185 | SH | | DFND | | 51,660 | 0 | 326,525 |
| RINGCENTRAL INC-CLASS A | COM | 76680R206 | 97,311 | 3,438,541 | SH | | DFND | | 565,347 | 0 | 2,873,194 |
| SAFETY INS GROUP INC | COM | 78648T100 | 442 | 6,312 | SH | | DFND | | 1,170 | 0 | 5,142 |
| SALESFORCE COM INC | COM | 79466L302 | 20,781 | 251,919 | SH | | DFND | | 49,872 | 0 | 202,047 |
| SANGAMO THERAPEUTICS INC COM | COM | 800677106 | 154 | 29,576 | SH | | DFND | | 0 | 0 | 29,576 |
| SAREPTA THERAPEUTICS INC COM | COM | 803607100 | 434 | 14,659 | SH | | DFND | | 5,806 | 0 | 8,853 |
| SCIENTIFIC GAMES CRP CL A | COM | 80874P109 | 1,564 | 66,148 | SH | | DFND | | 15,345 | 0 | 50,803 |
| SCOUT24 AG NPV 144A ISIN #DE000A12DM80 SEDOL #BYT9340 | COM | D345XT105 | 72 | 2,187 | SH | | DFND | | 422 | 0 | 1,765 |
| SECTOR SPDR TR SHS BEN INT TECHNOLOGY | COM | 81369Y803 | 1,690 | 31,695 | SH | | DFND | | 6,296 | 0 | 25,399 |
| SENESTECH INC COM | COM | 81720R109 | 8,304 | 1,049,790 | SH | | DFND | | 112,054 | 0 | 937,736 |
| SEQUANS COMMUNICATIONS SPON ADR EA REPR 1 ORD SHS | COM | 817323108 | 191 | 69,277 | SH | | DFND | | 5,920 | 0 | 63,357 |
| SERVICENOW INC COM USD0.001 | COM | 81762P102 | 12,525 | 143,193 | SH | | DFND | | 24,662 | 0 | 118,531 |
| SHAKE SHACK INC CL A | COM | 819047101 | 73,173 | 2,190,807 | SH | | DFND | | 501,301 | 0 | 1,689,506 |
| SHERWIN WILLIAMS CO | COM | 824348106 | 819 | 2,640 | SH | | DFND | | 75 | 0 | 2,565 |
| SHOPIFY INC NPV SUBORDINATED A ISIN #CA82509L1076 SEDOL #BX865C7 | COM | 82509L107 | 17,674 | 259,564 | SH | | DFND | | 46,871 | 0 | 212,693 |
| SIENTRA INC COM USD0.01 | COM | 82621J105 | 6,884 | 817,609 | SH | | DFND | | 113,671 | 0 | 703,938 |
| SIGNATURE BK NEW YORK N Y COM | COM | 82669G104 | 3,825 | 25,774 | SH | | DFND | | 4,692 | 0 | 21,082 |
| SILVER WHEATON CORPORATION COM NPV ISIN #CA8283361076 SEDOL #B05 | COM | 828336107 | 1,935 | 92,867 | SH | | DFND | | 635 | 0 | 92,232 |
| SILVERCREST METALS INC COM NPV ISIN #CA8283631015 SEDOL #BYVY3D2 | COM | 828363101 | 1,101 | 712,761 | SH | | DFND | | 105,682 | 0 | 607,079 |
| SIRIUS XM HLDGS INC COM | COM | 82968B103 | 155 | 30,140 | SH | | DFND | | 5,808 | 0 | 24,332 |
| SITEONE LANDSCAPE SUPPLY INC COM | COM | 82982L103 | 15,779 | 325,951 | SH | | DFND | | 36,089 | 0 | 289,862 |
| SIX FLAGS ENTMT CORP NEW COM | COM | 83001A102 | 9,439 | 158,661 | SH | | DFND | | 51,370 | 0 | 107,291 |
| SMART SAND INC COM | COM | 83191H107 | 6,227 | 383,190 | SH | | DFND | | 70,381 | 0 | 312,809 |
| SNAP INC CL A | COM | 83304A106 | 48,425 | 2,149,349 | SH | | DFND | | 430,664 | 0 | 1,718,685 |
| SPARK THERAPEUTICS INC COM | COM | 84652J103 | 367 | 6,887 | SH | | DFND | | 3,206 | 0 | 3,681 |
| SPIRIT AIRLS INC COM | COM | 848577102 | 31,667 | 596,711 | SH | | DFND | | 63,252 | 0 | 533,459 |
| SPLUNK INC COM USD0.001 | COM | 848637104 | 8,640 | 138,708 | SH | | DFND | | 22,067 | 0 | 116,641 |
| SQUARE INC CL A | COM | 852234103 | 7,513 | 434,779 | SH | | DFND | | 54,899 | 0 | 379,880 |
| SS&C TECHNOLOGIES HLDGS INC COM | COM | 78467J100 | 26,050 | 735,887 | SH | | DFND | | 119,833 | 0 | 616,054 |
| STARBUCKS CORP COM USD0.001 | COM | 855244109 | 1,850 | 31,681 | SH | | DFND | | 4,752 | 0 | 26,929 |
| STRAIGHT PATH COMMUNICATIONS INC COM USD0.01 CL B | COM | 862578101 | 26,784 | 744,617 | SH | | DFND | | 120,107 | 0 | 624,510 |
| SUMMIT MATLS INC CL A | COM | 86614U100 | 8,478 | 343,092 | SH | | DFND | | 6,334 | 0 | 336,758 |
| SUNRUN INC COM | COM | 86771W105 | 329 | 60,884 | SH | | DFND | | 6,332 | 0 | 54,552 |
| SVB FINL GROUP | COM | 78486Q101 | 3,874 | 20,816 | SH | | DFND | | 3,749 | 0 | 17,067 |
| T MOBILE US INC COM | COM | 872590104 | 322 | 4,992 | SH | | DFND | | 474 | 0 | 4,518 |
| TAKE-TWO INTERACTIVE SOFTWARE COM | COM | 874054109 | 680 | 11,468 | SH | | DFND | | 6,272 | 0 | 5,196 |
| TAL EDUCATION GROUP ADS EA REPR 2 CL A ORD SHS | COM | 874080104 | 81 | 756 | SH | | DFND | | 479 | 0 | 277 |
| TALEND SA ADR EACH REP 1 ORD SHS | COM | 874224207 | 1,240 | 41,648 | SH | | DFND | | 7,387 | 0 | 34,261 |
| TELADOC INC COM | COM | 87918A105 | 28 | 1,126 | SH | | DFND | | 193 | 0 | 933 |
| TENCENT HOLDINGS LIMITED HKD0.00002 ISIN #KYG875721634 SEDOL #BM | COM | G87572163 | 50,351 | 1,756,297 | SH | | DFND | | 506,139 | 0 | 1,250,158 |
| TESLA INC COM | COM | 88160R101 | 192,038 | 690,038 | SH | | DFND | | 242,193 | 0 | 447,845 |
| THERAPEUTICSMD INC COM | COM | 88338N107 | 22,030 | 3,059,690 | SH | | DFND | | 1,083,355 | 0 | 1,976,335 |
| TIME INC NEW COM | COM | 887228104 | 37 | 1,927 | SH | | DFND | | 0 | 0 | 1,927 |
| TRACTOR SUPPLY CO | COM | 892356106 | 1,933 | 28,033 | SH | | DFND | | 6,049 | 0 | 21,984 |
| TRANSDIGM GROUP INC COM | COM | 893641100 | 6,517 | 29,603 | SH | | DFND | | 786 | 0 | 28,817 |
| TRIPADVISOR INC COM | COM | 896945201 | 135 | 3,133 | SH | | DFND | | 97 | 0 | 3,036 |
| TSO3 INC COM ISIN #CA8730151013 SEDOL #2798518 | COM | 873015101 | 12,766 | 5,370,685 | SH | | DFND | | 478,396 | 0 | 4,892,289 |
| TWILIO INC CL A | COM | 90138F102 | 2,430 | 84,158 | SH | | DFND | | 13,731 | 0 | 70,427 |
| TWITTER INC COM USD0.000005 | COM | 90184L102 | 62 | 4,136 | SH | | DFND | | 4,136 | 0 | 0 |
| ULTA BEAUTY INC COM | COM | 90384S303 | 82,486 | 289,190 | SH | | DFND | | 40,033 | 0 | 249,157 |
| ULTIMATE SOFTWARE GROUP INC | COM | 90385D107 | 3,477 | 17,810 | SH | | DFND | | 2,693 | 0 | 15,117 |
| UNDER ARMOUR INC COM STK USD0.000333 CLASS A | COM | 904311107 | 31 | 1,556 | SH | | DFND | | 1,500 | 0 | 56 |
| UNIVERSAL DISPLAY CORP | COM | 91347P105 | 312 | 3,618 | SH | | DFND | | 2,734 | 0 | 884 |
| VALIDUS HOLDING LTD COM STK USD0.175 | COM | G9319H102 | 6,064 | 107,531 | SH | | DFND | | 27,428 | 0 | 80,103 |
| VANECK VECTORS ETF TR GOLD MINERS ETF | COM | 92189F106 | 11,842 | 519,158 | SH | | DFND | | 17,175 | 0 | 501,983 |
| VEEVA SYS INC CL A COM | COM | 922475108 | 46,482 | 906,439 | SH | | DFND | | 294,292 | 0 | 612,147 |
| VIVENDI SA EUR5.50 ISIN #FR0000127771 SEDOL #4834777 | COM | F97982106 | 21,386 | 1,097,119 | SH | | DFND | | 75,418 | 0 | 1,021,701 |
| VOCERA COMMUNICATIONS INC COM | COM | 92857F107 | 5,901 | 237,658 | SH | | DFND | | 43,998 | 0 | 193,660 |
| VULCAN MATERIALS CO | COM | 929160109 | 105 | 869 | SH | | DFND | | 28 | 0 | 841 |
| WAGEWORKS INC COM USD0.001 | COM | 930427109 | 47 | 656 | SH | | DFND | | 126 | 0 | 530 |
| WEIBO CORP SPONSORED ADR | COM | 948596101 | 3,690 | 70,725 | SH | | DFND | | 10,511 | 0 | 60,214 |
| WELLS FARGO &COMPANY COM USD1.666 | COM | 949746101 | 1,568 | 28,178 | SH | | DFND | | 2,770 | 0 | 25,408 |
| WORKDAY INC CL A | COM | 98138H101 | 8,926 | 107,180 | SH | | DFND | | 20,085 | 0 | 87,095 |
| XILINX INC | COM | 983919101 | 41,277 | 713,023 | SH | | DFND | | 51,460 | 0 | 661,563 |
| XTREME DRILLING CORP ISIN #CA98419V1004 SEDOL #B7J8QB6 | COM | 98419V100 | 2,362 | 1,471,901 | SH | | DFND | | 158,429 | 0 | 1,313,472 |
| YOOX NET-A-PORTER GROUP NPV ISIN #IT0003540470 SEDOL #B4YC9W4 | COM | T9846S106 | 308 | 12,892 | SH | | DFND | | 3,035 | 0 | 9,857 |
| ZALANDO SE NPV ISIN #DE000ZAL1111 SEDOL #BQV0SV7 | COM | D98423102 | 415 | 10,327 | SH | | DFND | | 4,049 | 0 | 6,278 |
| ZAYO GROUP HLDGS INC COM | COM | 98919V105 | 241 | 7,312 | SH | | DFND | | 617 | 0 | 6,695 |
| ZENDESK INC COM USD0.01 | COM | 98936J101 | 6,465 | 230,572 | SH | | DFND | | 38,675 | 0 | 191,897 |
| ZILLOW GROUP INC CL A | COM | 98954M101 | 22,497 | 665,409 | SH | | DFND | | 49,540 | 0 | 615,869 |
| ZILLOW GROUP INC CL C CAP STK | COM | 98954M200 | 38,778 | 1,151,707 | SH | | DFND | | 90,754 | 0 | 1,060,953 |
| ZOETIS INC COM USD0.01 CL A | COM | 98978V103 | 411 | 7,695 | SH | | DFND | | 237 | 0 | 7,458 |
