Gilder Gagnon Howe & Co 13F-HR Quarterly holdings report by institutional manager

The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE

OMB APPROVAL

OMB Number:		3235-0006
Expires:	Oct 31, 2018
Estimated average burden
hours per response:		23.8

COLUMN 1	COLUMN 2	COLUMN 3	COLUMN 4	COLUMN 5			COLUMN 6	COLUMN 7	COLUMN 8
			VALUE	SHRS OR	SH/	PUT/	INVESTMENT	OTHER	VOTING AUTHORITY
NAME OF ISSUER	TITLE OF CLASS	CUSIP	(x$1000)	PRN AMT	PRN	CALL	DISCRETION	MANAGER	SOLE	SHARED	NONE
10X GENOMICS INC	CL A COM	88025U109	114,167	766,428	SH		DFND		0	0	766,428
1LIFE HEALTHCARE INC	COM	68269G107	89,873	5,115,128	SH		DFND		0	0	5,115,128
2U INC	COM	90214J101	1,721	85,744	SH		DFND		0	0	85,744
ABIOMED INC	COM	003654100	59,971	166,972	SH		DFND		0	0	166,972
ACCEL ENTERTAINMENT INC	COM CL A1	00436Q106	31	2,400	SH		DFND		0	0	2,400
ACTIVISION BLIZZARD INC	COM	00507V109	1,498	22,514	SH		DFND		0	0	22,514
ADAPTIVE BIOTECHNOLOGIES COR	COM	00650F109	26,451	942,666	SH		DFND		0	0	942,666
ADOBE SYSTEMS INCORPORATED	COM	00724F101	62,758	110,672	SH		DFND		0	0	110,672
ADYEN NV REG S	COMMONSTOCK	N3501V104	69,659	26,500	SH		DFND		0	0	26,500
AFFIRM HLDGS INC	COM CL A	00827B106	230,834	2,295,487	SH		DFND		0	0	2,295,487
AFYA LTD	CL A COM	G01125106	29	1,847	SH		DFND		0	0	1,847
AIRBNB INC	COM CL A	009066101	39,705	238,483	SH		DFND		0	0	238,483
AIRSCULPT TECHNOLOGIES INC	COM	009496100	4,022	233,961	SH		DFND		0	0	233,961
AIRSPAN NETWORKS HOLDINGS IN	COM	00951K104	169	44,720	SH		DFND		0	0	44,720
ALAMOS GOLD INC NEW	COM CL A	011532108	3,911	508,609	SH		DFND		0	0	508,609
ALECTOR INC	COM	014442107	13,360	646,963	SH		DFND		0	0	646,963
ALIBABA GROUP HLDG LTD	SPONSORED ADS	01609W102	1	7	SH		DFND		0	0	7
ALLAKOS INC	COM	01671P100	165	16,859	SH		DFND		0	0	16,859
ALLBIRDS INC	COM CL A	01675A109	2,922	193,786	SH		DFND		0	0	193,786
ALLOGENE THERAPEUTICS INC	COM	019770106	0	29	SH		DFND		0	0	29
ALNYLAM PHARMACEUTICALS INC	COM	02043Q107	142,374	839,568	SH		DFND		0	0	839,568
ALPHABET INC	CAP STK CL A	02079K305	110,639	38,190	SH		DFND		0	0	38,190
ALPHABET INC	CAP STK CL C	02079K107	151,810	52,464	SH		DFND		0	0	52,464
ALTERYX INC	COM CL A	02156B103	2	30	SH		DFND		0	0	30
AMAZON COM INC	COM	023135106	497,191	149,112	SH		DFND		0	0	149,112
AMBARELLA INC	SHS	G037AX101	15,521	76,501	SH		DFND		0	0	76,501
AMC ENTMT HLDGS INC	CL A COM	00165C104	6	203	SH		DFND		0	0	203
AMERICAN TOWER CORP NEW	COM	03027X100	22,043	75,362	SH		DFND		0	0	75,362
ANAPLAN INC	COM	03272L108	2	41	SH		DFND		0	0	41
ANTERIX INC	COM	03676C100	551	9,375	SH		DFND		0	0	9,375
APA CORPORATION	COM	03743Q108	3,937	146,410	SH		DFND		0	0	146,410
APOLLO ENDOSURGERY INC	COM	03767D108	4,454	528,359	SH		DFND		0	0	528,359
APPFOLIO INC	COM CL A	03783C100	48,490	400,549	SH		DFND		0	0	400,549
APPLE INC	COM	037833100	28,048	157,957	SH		DFND		0	0	157,957
APPLIED MATLS INC	COM	038222105	26	168	SH		DFND		0	0	168
ARCHAEA ENERGY INC	COM CL A	03940F103	30,965	1,693,945	SH		DFND		0	0	1,693,945
ARCTOS NORTHSTAR ACQUIS CORP	SHS CL A	G0477L100	1,708	175,699	SH		DFND		0	0	175,699
ARCUS BIOSCIENCES INC	COM	03969F109	11,844	292,668	SH		DFND		0	0	292,668
ARENA PHARMACEUTICALS INC	COM NEW	040047607	1,628	17,519	SH		DFND		0	0	17,519
ARGENX SE	SPONSORED ADR	04016X101	3,866	11,040	SH		DFND		0	0	11,040
ARGO GROUP INTL HLDGS LTD	COM	G0464B107	366	6,302	SH		DFND		0	0	6,302
ARISTA NETWORKS INC	COM	040413106	15,655	108,906	SH		DFND		0	0	108,906
ARITZIA INC SUB VTG SHS ISIN CA04045U1021 SEDOL BDCG2C2	COMMONSTOCK	04045U102	31,707	765,054	SH		DFND		0	0	765,054
ARLO TECHNOLOGIES INC	COM	04206A101	1,873	178,595	SH		DFND		0	0	178,595
ARTERIS INC	COM	04302A104	16,658	789,126	SH		DFND		0	0	789,126
ARVINAS INC	COM	04335A105	126,110	1,535,300	SH		DFND		0	0	1,535,300
ASANA INC	CL A	04342Y104	109,519	1,469,063	SH		DFND		0	0	1,469,063
ASHTEAD GROUP ORD GBP010 ISIN GB0000536739 SEDOL 0053673	COMMONSTOCK	G05320109	7	85	SH		DFND		0	0	85
ASPEN AEROGELS INC	COM	04523Y105	4,236	85,085	SH		DFND		0	0	85,085
AST SPACEMOBILE INC	COM CL A	00217D100	389	49,050	SH		DFND		0	0	49,050
ATAI LIFE SCIENCES NV	SHS	N0731H103	1,976	259,040	SH		DFND		0	0	259,040
ATLASSIAN CORP PLC	CL A	G06242104	74,000	194,077	SH		DFND		0	0	194,077
ATRICURE INC	COM	04963C209	3	42	SH		DFND		0	0	42
AURINIA PHARMACEUTICALS INC	COM	05156V102	4,466	195,283	SH		DFND		0	0	195,283
AUSTERLITZ ACQUISITION CORP	COM CL A	G0633U101	6,854	705,101	SH		DFND		0	0	705,101
AUSTERLITZ ACQUISITION CORP	SHS CL A	G0633D109	5,153	530,695	SH		DFND		0	0	530,695
AUTODESK INC	COM	052769106	1,423	5,060	SH		DFND		0	0	5,060
AUTOSTORE HOLDINGS LTD USD001 144A REG S ISIN BMG0670A1099 SED	COMMONSTOCK	G0670A109	4,040	1,022,794	SH		DFND		0	0	1,022,794
AVID TECHNOLOGY INC	COM	05367P100	63,919	1,962,521	SH		DFND		0	0	1,962,521
AVIDITY BIOSCIENCES INC	COM	05370A108	736	30,983	SH		DFND		0	0	30,983
AXIS BANK GDR REG S ISIN US05462W1099 SEDOL B06CDW2	COMMONSTOCK	05462W109	2,951	63,874	SH		DFND		0	0	63,874
AZEK CO INC	CL A	05478C105	56,612	1,224,305	SH		DFND		0	0	1,224,305
AZUL S A	SPONSR ADR PFD	05501U106	13,232	1,002,434	SH		DFND		0	0	1,002,434
BAMBUSER AB NPV ISIN SE0009663834 SEDOL BD8Z3Y2	COMMONSTOCK	W1R91S102	13,438	7,486,157	SH		DFND		0	0	7,486,157
BASICFIT NV 144A REG S ISIN NL0011872650 SEDOL BD9Y9B7	COMMONSTOCK	N10058100	29	599	SH		DFND		0	0	599
BEACON ROOFING SUPPLY INC	COM	073685109	11,164	194,663	SH		DFND		0	0	194,663
BEAM THERAPEUTICS INC	COM	07373V105	12,442	156,131	SH		DFND		0	0	156,131
BERKLEY W R CORP	COM	084423102	6,664	80,884	SH		DFND		0	0	80,884
BERKSHIRE HATHAWAY INC DEL	CL B NEW	084670702	1,548	5,176	SH		DFND		0	0	5,176
BIOCRYST PHARMACEUTICALS INC	COM	09058V103	4,720	340,779	SH		DFND		0	0	340,779
BIOHAVEN PHARMACTL HLDG CO L	COM	G11196105	35,623	258,497	SH		DFND		0	0	258,497
BIONTECH SE	SPONSORED ADS	09075V102	92,054	357,074	SH		DFND		0	0	357,074
BLOCK INC	CL A	852234103	186,353	1,153,819	SH		DFND		0	0	1,153,819
BOOT BARN HLDGS INC	COM	099406100	10	81	SH		DFND		0	0	81
BRAZE INC	COM CL A	10576N102	4,555	59,029	SH		DFND		0	0	59,029
BRIDGEBIO PHARMA INC	COM	10806X102	14,099	845,260	SH		DFND		0	0	845,260
BRP GROUP INC	COM CL A	05589G102	7,153	198,077	SH		DFND		0	0	198,077
BYRNA TECHNOLOGIES INC	COM NEW	12448X201	708	53,035	SH		DFND		0	0	53,035
CALIX INC	COM	13100M509	239,894	2,999,795	SH		DFND		0	0	2,999,795
CANADIAN PAC RY LTD	COM	13645T100	697	9,686	SH		DFND		0	0	9,686
CARL ZEISS MEDITEC AG NPV ISIN DE0005313704 SEDOL 5922961	COMMONSTOCK	D14895102	2,427	11,924	SH		DFND		0	0	11,924
CARPARTS COM INC	COM	14427M107	26,317	2,349,730	SH		DFND		0	0	2,349,730
CARVANA CO	CL A	146869102	150,972	651,331	SH		DFND		0	0	651,331
CATAPULT GROUP INTERNATIONAL ISIN AU000000CAT9 SEDOL BTL0Y76	COMMONSTOCK	Q2159P101	183	161,974	SH		DFND		0	0	161,974
CCC INTELLIGENT SOLUTIONS HL	COM	12510Q100	665	58,376	SH		DFND		0	0	58,376
CELLNEX TELECOM SAU EUR025 144A REG S ISIN ES0105066007 SEDOL	COMMONSTOCK	E2R41M104	4,752	81,945	SH		DFND		0	0	81,945
CHARLES RIV LABS INTL INC	COM	159864107	8,223	21,824	SH		DFND		0	0	21,824
CHART INDS INC	COM	16115Q308	87	545	SH		DFND		0	0	545
CHEGG INC	COM	163092109	44,101	1,436,529	SH		DFND		0	0	1,436,529
CHEWY INC	CL A	16679L109	23,447	397,602	SH		DFND		0	0	397,602
CHIPOTLE MEXICAN GRILL INC	COM	169656105	40	23	SH		DFND		0	0	23
CHUBB LIMITED	COM	H1467J104	23,242	120,232	SH		DFND		0	0	120,232
CITIGROUP INC	COM NEW	172967424	2	35	SH		DFND		0	0	35
CLASS ACCELERATION CORP	COM	18274B106	8,903	916,862	SH		DFND		0	0	916,862
CLEAR SECURE INC	COM CL A	18467V109	6	191	SH		DFND		0	0	191
CLEARFIELD INC	COM	18482P103	7,131	84,469	SH		DFND		0	0	84,469
CLOUDFLARE INC	CL A COM	18915M107	552,667	4,202,789	SH		DFND		0	0	4,202,789
CODEXIS INC	COM	192005106	93,664	2,995,317	SH		DFND		0	0	2,995,317
COINBASE GLOBAL INC	COM CL A	19260Q107	186,060	737,249	SH		DFND		0	0	737,249
COMMSCOPE HLDG CO INC	COM	20337X109	7,412	671,374	SH		DFND		0	0	671,374
COMPASS INC	CL A	20464U100	446	49,041	SH		DFND		0	0	49,041
CONFLUENT INC	CLASS A COM	20717M103	413,123	5,418,720	SH		DFND		0	0	5,418,720
CONTROLADORA VUELA COMP DE A	SPON ADR RP 10	21240E105	89,915	5,003,593	SH		DFND		0	0	5,003,593
CORECIVIC INC	COM	21871N101	81	8,079	SH		DFND		0	0	8,079
COUCHBASE INC	COM	22207T101	25,498	1,021,569	SH		DFND		0	0	1,021,569
COUPA SOFTWARE INC	COM	22266L106	8,071	51,063	SH		DFND		0	0	51,063
COVETRUS INC	COM	22304C100	0	8	SH		DFND		0	0	8
CROCS INC	COM	227046109	36	277	SH		DFND		0	0	277
CROWDSTRIKE HLDGS INC	CL A	22788C105	29,158	142,410	SH		DFND		0	0	142,410
CS DISCO INC	COM	126327105	3,736	104,510	SH		DFND		0	0	104,510
CURALEAF HOLDINGS INC SUB VTG SHS ISIN CA23126M1023 SEDOL BGY4	COMMONSTOCK	23126M102	20	2,203	SH		DFND		0	0	2,203
CUSTOM TRUCK ONE SOURCE INC	COM CL A	23204X103	32,449	4,056,096	SH		DFND		0	0	4,056,096
D R HORTON INC	COM	23331A109	3,721	34,311	SH		DFND		0	0	34,311
DATADOG INC	CL A COM	23804L103	19,277	108,233	SH		DFND		0	0	108,233
DEERE & CO	COM	244199105	43,866	127,930	SH		DFND		0	0	127,930
DENALI THERAPEUTICS INC	COM	24823R105	129,345	2,900,114	SH		DFND		0	0	2,900,114
DENBURY INC	COM	24790A101	47,369	618,481	SH		DFND		0	0	618,481
DEXCOM INC	COM	252131107	111,968	208,527	SH		DFND		0	0	208,527
DICKS SPORTING GOODS INC	COM	253393102	154,491	1,343,513	SH		DFND		0	0	1,343,513
DIGITAL WORLD ACQUISITION CO	CLASS A COM	25400Q105	1,807	35,129	SH		DFND		0	0	35,129
DISH NETWORK CORPORATION	CL A	25470M109	30,524	940,944	SH		DFND		0	0	940,944
DISNEY WALT CO	COM	254687106	13,904	89,767	SH		DFND		0	0	89,767
DIVERSIFIED ENERGY COMPANY PLC ORD GBP001 ISIN GB00BYX7JT74 SE	COMMONSTOCK	G2891G105	13,650	9,653,441	SH		DFND		0	0	9,653,441
DOCUSIGN INC	COM	256163106	203,098	1,333,451	SH		DFND		0	0	1,333,451
DOLLAR TREE INC	COM	256746108	457	3,252	SH		DFND		0	0	3,252
DOWNEY FINL CORP	COMMONSTOCK	261018105	0	200	SH		DFND		0	0	200
DRAFTKINGS INC	COM CL A	26142R104	349	12,721	SH		DFND		0	0	12,721
DUOLINGO INC	CL A COM	26603R106	103,900	979,168	SH		DFND		0	0	979,168
DUTCH BROS INC	CL A	26701L100	160	3,138	SH		DFND		0	0	3,138
ENDAVA PLC	ADS	29260V105	774	4,611	SH		DFND		0	0	4,611
ENDEAVOUR MINING PLC ORD USD001 ISIN GB00BL6K5J42 SEDOL BN7KJ	COMMONSTOCK	G3042J105	7,239	329,751	SH		DFND		0	0	329,751
ENOVIX CORPORATION	COM	293594107	117,606	4,311,083	SH		DFND		0	0	4,311,083
ENPHASE ENERGY INC	COM	29355A107	216,426	1,183,044	SH		DFND		0	0	1,183,044
EPAM SYS INC	COM	29414B104	164,500	246,092	SH		DFND		0	0	246,092
EQRX INC	COM	26886C107	4,830	708,208	SH		DFND		0	0	708,208
EQUATOR EXPLORATION COM STK NPV	COMMONSTOCK	G3084F128	0	215,000	SH		DFND		0	0	215,000
ETSY INC	COM	29786A106	78,086	356,653	SH		DFND		0	0	356,653
EUROPEAN WAX CTR INC	CLASS A COM	29882P106	335	11,042	SH		DFND		0	0	11,042
EVENTBRITE INC	COM CL A	29975E109	1,091	62,534	SH		DFND		0	0	62,534
EVERI HLDGS INC	COM	30034T103	46,221	2,164,899	SH		DFND		0	0	2,164,899
EXACT SCIENCES CORP	COM	30063P105	109,637	1,408,672	SH		DFND		0	0	1,408,672
FASTLY INC	CL A	31188V100	30,503	860,455	SH		DFND		0	0	860,455
FATHOM HOLDINGS INC	COM	31189V109	8,259	403,671	SH		DFND		0	0	403,671
FERGUSON PLC ORD GBP010 ISIN JE00BJVNSS43 SEDOL BJVNSS4	COMMONSTOCK	ZZDKWOTT6	18,934	106,670	SH		DFND		0	0	106,670
FIGS INC	CL A	30260D103	12,556	455,586	SH		DFND		0	0	455,586
FINWISE BANCORP	COM	31813A109	5,300	384,323	SH		DFND		0	0	384,323
FLOOR & DECOR HLDGS INC	CL A	339750101	148,497	1,142,195	SH		DFND		0	0	1,142,195
FLUIDRA SA EUR1 ISIN ES0137650018 SEDOL B28V440	COMMONSTOCK	E52619108	29,985	785,987	SH		DFND		0	0	785,987
FLYWIRE CORPORATION	COM VTG	302492103	3,139	82,471	SH		DFND		0	0	82,471
FORD MTR CO DEL	COM	345370860	20	969	SH		DFND		0	0	969
FOREST ROAD ACQUISITION COR	CL A	34619V103	4,421	454,358	SH		DFND		0	0	454,358
FRANCO NEV CORP	COM	351858105	9,864	71,325	SH		DFND		0	0	71,325
FRANKLIN COVEY CO	COM	353469109	17	376	SH		DFND		0	0	376
FRESHPET INC	COM	358039105	150,757	1,582,418	SH		DFND		0	0	1,582,418
FRESHWORKS INC	CLASS A COM	358054104	104,875	3,993,709	SH		DFND		0	0	3,993,709
FRIENDLY ENERGY EXPLORATION COM NPV	COMMONSTOCK	35846A200	0	690	SH		DFND		0	0	690
FRONTIER GROUP HLDGS INC	COM	35909R108	3,827	282,046	SH		DFND		0	0	282,046
GAIA INC NEW	CL A	36269P104	14	1,590	SH		DFND		0	0	1,590
GALAPAGOS NV NPV ISIN BE0003818359 SEDOL B07Q2V5	COMMONSTOCK	B44170106	336	6,009	SH		DFND		0	0	6,009
GALWAY METALS INC COM NPV ISIN CA3645852086 SEDOL BDXGDC8	COMMONSTOCK	364585208	837	1,732,619	SH		DFND		0	0	1,732,619
GANNETT CO INC	COM	36472T109	7	1,324	SH		DFND		0	0	1,324
GARRETT MOTION INC	COM	366505105	8,808	1,096,860	SH		DFND		0	0	1,096,860
GENERAC HLDGS INC	COM	368736104	12	34	SH		DFND		0	0	34
GEOPARK LTD	USD SHS	G38327105	4,101	358,159	SH		DFND		0	0	358,159
GINKGO BIOWORKS HOLDINGS INC	CL A SHS	37611X100	6,292	757,196	SH		DFND		0	0	757,196
GLADSTONE LD CORP	COM	376549101	11	335	SH		DFND		0	0	335
GLOBAL E ONLINE LTD	SHS	M5216V106	11,642	183,650	SH		DFND		0	0	183,650
GLOBANT S A	COM	L44385109	108,965	346,923	SH		DFND		0	0	346,923
GOGOLD RES INC COM ISIN CA38045Y1025 SEDOL B60BNP0	COMMONSTOCK	38045Y102	2,320	967,126	SH		DFND		0	0	967,126
GOLDEN MINERALS CO	COM	381119106	16	46,847	SH		DFND		0	0	46,847
GOLDMAN SACHS GROUP INC	COM	38141G104	123	322	SH		DFND		0	0	322
GORES HLDGS VIII INC	CL A	382863108	394	38,606	SH		DFND		0	0	38,606
GRID DYNAMICS HLDGS INC	CL A	39813G109	910	23,972	SH		DFND		0	0	23,972
GROCERY OUTLET HLDG CORP	COM	39874R101	8	270	SH		DFND		0	0	270
GUARDANT HEALTH INC	COM	40131M109	417	4,167	SH		DFND		0	0	4,167
GUIDEWIRE SOFTWARE INC	COM	40171V100	651	5,737	SH		DFND		0	0	5,737
H & E EQUIPMENT SERVICES INC	COM	404030108	5,713	129,052	SH		DFND		0	0	129,052
HASHICORP INC	COM CL A	418100103	41,877	459,985	SH		DFND		0	0	459,985
HDFC BANK LTD	SPONSORED ADS	40415F101	10,643	163,560	SH		DFND		0	0	163,560
HEARUSA INC NEW	COMMONSTOCK	422360305	0	375	SH		DFND		0	0	375
HEICO CORP NEW	CL A	422806208	8,329	64,809	SH		DFND		0	0	64,809
HEICO CORP NEW	COM	422806109	2,309	16,007	SH		DFND		0	0	16,007
HELLOFRESH SE ISIN DE000A161408 SEDOL BYWH8S0	COMMONSTOCK	D3R2MA100	45,274	603,335	SH		DFND		0	0	603,335
HONEST CO INC	COM	438333106	35,389	4,374,464	SH		DFND		0	0	4,374,464
HOUGHTON MIFFLIN HARCOURT CO	COM	44157R109	1,661	103,167	SH		DFND		0	0	103,167
HUBSPOT INC	COM	443573100	307,980	467,238	SH		DFND		0	0	467,238
ICICI BANK LIMITED	ADR	45104G104	10,559	533,562	SH		DFND		0	0	533,562
IDEX BIOMETRICS ASA NOK015 ISIN NO0003070609 SEDOL 5374216	COMMONSTOCK	R33736100	1,071	2,804,285	SH		DFND		0	0	2,804,285
II-VI INC	COM	902104108	2,171	31,774	SH		DFND		0	0	31,774
ILLUMINA INC	COM	452327109	2,533	6,658	SH		DFND		0	0	6,658
IMPINJ INC	COM	453204109	138,462	1,561,018	SH		DFND		0	0	1,561,018
INARI MED INC	COM	45332Y109	10,179	111,524	SH		DFND		0	0	111,524
INFINERA CORP	COM	45667G103	62,909	6,559,821	SH		DFND		0	0	6,559,821
INSPIRE MED SYS INC	COM	457730109	181,230	787,749	SH		DFND		0	0	787,749
INSULET CORP	COM	45784P101	4,558	17,131	SH		DFND		0	0	17,131
INTERBREW PLC GDREACH REPR 1 A SH REG S	COMMONSTOCK	45845T308	0	200	SH		DFND		0	0	200
INTL GNRL INSURANCE HLDNGS L	SHS	G4809J106	16,820	2,076,592	SH		DFND		0	0	2,076,592
INTUITIVE SURGICAL INC	COM NEW	46120E602	174,028	484,354	SH		DFND		0	0	484,354
INVITAE CORP	COM	46185L103	58,025	3,799,919	SH		DFND		0	0	3,799,919
IRHYTHM TECHNOLOGIES INC	COM	450056106	2,105	17,889	SH		DFND		0	0	17,889
IVERIC BIO INC	COM	46583P102	3,086	184,557	SH		DFND		0	0	184,557
JPMORGAN CHASE & CO	COM	46625H100	2,507	15,834	SH		DFND		0	0	15,834
KAMBI GROUP PLC EUR0003 ISIN MT0000780107 SEDOL BMNQDC1	COMMONSTOCK	X4170A107	38	1,386	SH		DFND		0	0	1,386
KB HOME	COM	48666K109	421	9,411	SH		DFND		0	0	9,411
KINSALE CAP GROUP INC	COM	49714P108	486	2,042	SH		DFND		0	0	2,042
KIRKLAND LAKE GOLD LTD	COM	49741E100	5,543	132,145	SH		DFND		0	0	132,145
KORN FERRY	COM NEW	500643200	16	211	SH		DFND		0	0	211
KORNIT DIGITAL LTD	SHS	M6372Q113	225,467	1,480,903	SH		DFND		0	0	1,480,903
KRATOS DEFENSE & SEC SOLUTIO	COM NEW	50077B207	329	16,975	SH		DFND		0	0	16,975
KYMERA THERAPEUTICS INC	COM	501575104	7,616	119,953	SH		DFND		0	0	119,953
LEMONADE INC	COM	52567D107	4,103	97,441	SH		DFND		0	0	97,441
LESLIES INC	COM	527064109	17,230	728,218	SH		DFND		0	0	728,218
LGI HOMES INC	COM	50187T106	51,211	331,505	SH		DFND		0	0	331,505
LI NING CO LTD HKD01 ISIN KYG5496K1242 SEDOL B01JCK9	COMMONSTOCK	G5496K124	31	2,866	SH		DFND		0	0	2,866
LIBERTY MEDIA CORP DEL	COM C BRAVES GRP	531229888	5,311	189,009	SH		DFND		0	0	189,009
LIBERTY MEDIA CORP DEL	COM SER C FRMLA	531229854	2,518	39,823	SH		DFND		0	0	39,823
LIFE TIME GROUP HOLDINGS INC	COMMON STOCK	53190C102	12,529	727,988	SH		DFND		0	0	727,988
LINDBLAD EXPEDITIONS HLDGS I	COM	535219109	36,004	2,307,933	SH		DFND		0	0	2,307,933
LIVE NATION ENTERTAINMENT IN	COM	538034109	44	364	SH		DFND		0	0	364
LIVE OAK BANCSHARES INC	COM	53803X105	393	4,498	SH		DFND		0	0	4,498
LOVESAC COMPANY	COM	54738L109	1,836	27,714	SH		DFND		0	0	27,714
LULULEMON ATHLETICA INC	COM	550021109	8,424	21,521	SH		DFND		0	0	21,521
LYFT INC	CL A COM	55087P104	2,282	53,414	SH		DFND		0	0	53,414
MAG SILVER CORP	COM	55903Q104	23,421	1,494,662	SH		DFND		0	0	1,494,662
MAGENTA THERAPEUTICS INC	COM	55910K108	16,283	3,675,608	SH		DFND		0	0	3,675,608
MAGNOLIA OIL & GAS CORP	CL A	559663109	37,604	1,992,782	SH		DFND		0	0	1,992,782
MAKO MINING CORP COM NPV ISIN CA56089A1030 SEDOL BFXPTG5	COMMONSTOCK	56089A103	737	2,584,957	SH		DFND		0	0	2,584,957
MARTIN MARIETTA MATLS INC	COM	573284106	38,251	86,831	SH		DFND		0	0	86,831
MASTERCARD INCORPORATED	CL A	57636Q104	27,444	76,378	SH		DFND		0	0	76,378
MAXAR TECHNOLOGIES INC	COM	57778K105	42,855	1,451,239	SH		DFND		0	0	1,451,239
MEDTECH ACQUISITION CORP	COM CL A	58507N105	6,978	706,233	SH		DFND		0	0	706,233
MEDTECH ACQUISITION CORP	UNIT 12/18/2025	58507N204	3,112	310,224	SH		DFND		0	0	310,224
MERCADOLIBRE INC	COM	58733R102	228,176	169,220	SH		DFND		0	0	169,220
META PLATFORMS INC	CL A	30303M102	34,927	103,842	SH		DFND		0	0	103,842
MGP INGREDIENTS INC NEW	COM	55303J106	2,112	24,849	SH		DFND		0	0	24,849
MICROSOFT CORP	COM	594918104	109,594	325,862	SH		DFND		0	0	325,862
MONDAY COM LTD	SHS	M7S64H106	5,345	17,314	SH		DFND		0	0	17,314
MONEYGRAM INTL INC	COM NEW	60935Y208	4,549	576,536	SH		DFND		0	0	576,536
MONGODB INC	CL A	60937P106	347,996	657,402	SH		DFND		0	0	657,402
MONOLITHIC PWR SYS INC	COM	609839105	21,098	42,766	SH		DFND		0	0	42,766
NAKED WINES PLC ORD GBP0075 ISIN GB00B021F836 SEDOL B021F83	COMMONSTOCK	G6361W102	9,265	1,050,788	SH		DFND		0	0	1,050,788
NATERA INC	COM	632307104	140,769	1,507,324	SH		DFND		0	0	1,507,324
NATIONAL VISION HLDGS INC	COM	63845R107	36	742	SH		DFND		0	0	742
NETCOMPANY GROUP AS DKK1 144A ISIN DK0060952919 SEDOL BFYDWS1	COMMONSTOCK	K7020C102	103,075	960,197	SH		DFND		0	0	960,197
NETFLIX INC	COM	64110L106	565,166	938,129	SH		DFND		0	0	938,129
NEW PAC METALS CORP	COM	64782A107	5,421	1,843,892	SH		DFND		0	0	1,843,892
NEW VISTA ACQUISITION CORP	CL A SHS	G6529L105	5,375	552,389	SH		DFND		0	0	552,389
NEW VISTA ACQUISITION CORP	UNIT 02/01/2026	G6529L113	11,842	1,184,161	SH		DFND		0	0	1,184,161
NEW YORK TIMES CO	CL A	650111107	127,269	2,634,960	SH		DFND		0	0	2,634,960
NEXTDOOR HOLDINGS INC	COM CL A	65345M108	1,012	128,241	SH		DFND		0	0	128,241
NIKE INC	CL B	654106103	24,813	148,875	SH		DFND		0	0	148,875
NU HLDGS LTD	ORD SHS CL A	G6683N103	394	41,967	SH		DFND		0	0	41,967
NV5 GLOBAL INC	COM	62945V109	89	644	SH		DFND		0	0	644
NVIDIA CORPORATION	COM	67066G104	235,063	799,234	SH		DFND		0	0	799,234
NYXOAH S A	SHS	B6S7WD106	1,078	46,872	SH		DFND		0	0	46,872
OCADO GROUP PLC ORD GBP002 ISIN GB00B3MBS747 SEDOL B3MBS74	COMMONSTOCK	G6718L106	217,628	9,575,443	SH		DFND		0	0	9,575,443
OKTA INC	CL A	679295105	249,710	1,113,931	SH		DFND		0	0	1,113,931
OLAPLEX HLDGS INC	COM	679369108	1,867	64,084	SH		DFND		0	0	64,084
OLINK HLDG AB	SPONSORED ADS	680710100	932	51,227	SH		DFND		0	0	51,227
ON HLDG AG	NAMEN AKT A	H5919C104	39,029	1,032,248	SH		DFND		0	0	1,032,248
ONEWATER MARINE INC	CL A COM	68280L101	60,305	989,098	SH		DFND		0	0	989,098
OPENDOOR TECHNOLOGIES INC	COM	683712103	853	58,369	SH		DFND		0	0	58,369
OPPFI INC	COM CL A	68386H103	996	219,487	SH		DFND		0	0	219,487
OPTION CARE HEALTH INC	COM NEW	68404L201	52,032	1,829,537	SH		DFND		0	0	1,829,537
OSCAR HEALTH INC	CL A	687793109	790	100,629	SH		DFND		0	0	100,629
OUTSET MED INC	COM	690145107	2,388	51,812	SH		DFND		0	0	51,812
OXFORD NANOPORE TECHNOLOGIES PLC ORD GBP00001 ISIN GB00BP6S8Z3	COMMONSTOCK	G6840E103	1,562	165,247	SH		DFND		0	0	165,247
PALOMAR HLDGS INC	COM	69753M105	4,400	67,934	SH		DFND		0	0	67,934
PAYPAL HLDGS INC	COM	70450Y103	5,415	28,715	SH		DFND		0	0	28,715
PELOTON INTERACTIVE INC	CL A COM	70614W100	110,669	3,094,777	SH		DFND		0	0	3,094,777
PENN TREATY AMERN CORP COM NEW	COMMONSTOCK	707874400	0	125	SH		DFND		0	0	125
PENSKE AUTOMOTIVE GRP INC	COM	70959W103	6,135	57,221	SH		DFND		0	0	57,221
PHATHOM PHARMACEUTICALS INC	COM	71722W107	10,741	546,055	SH		DFND		0	0	546,055
PINTEREST INC	CL A	72352L106	3,235	88,994	SH		DFND		0	0	88,994
PONTEM CORPORATION	SHS CL A	G71707106	2,648	270,201	SH		DFND		0	0	270,201
POOL CORP	COM	73278L105	177,101	312,900	SH		DFND		0	0	312,900
PROCORE TECHNOLOGIES INC	COM	74275K108	196,569	2,458,035	SH		DFND		0	0	2,458,035
PROFOUND MED CORP	COM NEW	74319B502	1,814	161,521	SH		DFND		0	0	161,521
PROQR THRAPEUTICS N V	SHS EURO	N71542109	11,047	1,379,123	SH		DFND		0	0	1,379,123
Q2 HLDGS INC	COM	74736L109	15,134	190,513	SH		DFND		0	0	190,513
QORVO INC	COM	74736K101	5,536	35,400	SH		DFND		0	0	35,400
QUANTA SVCS INC	COM	74762E102	23,222	202,526	SH		DFND		0	0	202,526
QUANTERIX CORP	COM	74766Q101	120,246	2,835,999	SH		DFND		0	0	2,835,999
REDFIN CORP	COM	75737F108	2,887	75,192	SH		DFND		0	0	75,192
RELAY THERAPEUTICS INC	COM	75943R102	24,468	796,747	SH		DFND		0	0	796,747
REMITLY GLOBAL INC	COM	75960P104	21,163	1,026,339	SH		DFND		0	0	1,026,339
RENALYTIX PLC	ADS	75973T101	48,936	3,077,726	SH		DFND		0	0	3,077,726
RENALYTIX PLC ORDINARY SHARES ISIN GB00BYWL4Y04 SEDOL BYWL4Y0	COMMONSTOCK	G7489R108	401	47,725	SH		DFND		0	0	47,725
RENT THE RUNWAY INC	COM CL A	76010Y103	41,874	5,137,916	SH		DFND		0	0	5,137,916
REPARE THERAPEUTICS INC	COM	760273102	0	17	SH		DFND		0	0	17
REPLIGEN CORP	COM	759916109	116,679	440,565	SH		DFND		0	0	440,565
REYNA SILVER CORP COM NPV ISIN CA76170Q1063 SEDOL BMG11D0	COMMONSTOCK	76170Q106	1,206	2,030,883	SH		DFND		0	0	2,030,883
RIGHTMOVE ORD GBP0001 ISIN GB00BGDT3G23 SEDOL BGDT3G2	COMMONSTOCK	G7565D106	8,995	835,356	SH		DFND		0	0	835,356
RINGCENTRAL INC	CL A	76680R206	82,446	440,063	SH		DFND		0	0	440,063
RIVIAN AUTOMOTIVE INC	COM CL A	76954A103	18,075	174,322	SH		DFND		0	0	174,322
ROBLOX CORP	CL A	771049103	215,475	2,088,747	SH		DFND		0	0	2,088,747
ROKU INC	COM CL A	77543R102	364,664	1,598,003	SH		DFND		0	0	1,598,003
ROYALTY PHARMA PLC	SHS CLASS A	G7709Q104	8	200	SH		DFND		0	0	200
SAFARICOM PLC KES005 ISIN KE1000001402 SEDOL B2QN3J6	COMMONSTOCK	V74587102	29,555	88,120,923	SH		DFND		0	0	88,120,923
SAFETY INS GROUP INC	COM	78648T100	108	1,269	SH		DFND		0	0	1,269
SALESFORCE COM INC	COM	79466L302	35,985	141,600	SH		DFND		0	0	141,600
SAREPTA THERAPEUTICS INC	COM	803607100	703	7,808	SH		DFND		0	0	7,808
SEA LTD	SPONSORD ADS	81141R100	10	46	SH		DFND		0	0	46
SEAGEN INC	COM	81181C104	1,920	12,421	SH		DFND		0	0	12,421
SEMLER SCIENTIFIC INC	COM	81684M104	5,115	55,811	SH		DFND		0	0	55,811
SENESTECH INC	COM NEW	81720R208	27	28,045	SH		DFND		0	0	28,045
SENTINELONE INC	CL A	81730H109	1,381	27,358	SH		DFND		0	0	27,358
SERVICENOW INC	COM	81762P102	55,493	85,492	SH		DFND		0	0	85,492
SHAKE SHACK INC	CL A	819047101	191,253	2,650,404	SH		DFND		0	0	2,650,404
SHENANDOAH TELECOMMUNICATION	COM	82312B106	343	13,449	SH		DFND		0	0	13,449
SHERWIN WILLIAMS CO	COM	824348106	1,555	4,417	SH		DFND		0	0	4,417
SHOALS TECHNOLOGIES GROUP IN	CL A	82489W107	3,008	123,768	SH		DFND		0	0	123,768
SHOCKWAVE MED INC	COM	82489T104	246,873	1,384,358	SH		DFND		0	0	1,384,358
SHOP APOTHEKE EUROPE NV NPV ISIN NL0012044747 SEDOL BYYH7G9	COMMONSTOCK	N7975Z103	27,258	219,469	SH		DFND		0	0	219,469
SHOPIFY INC	CL A	82509L107	511,434	371,307	SH		DFND		0	0	371,307
SHOTSPOTTER INC	COM	82536T107	41,937	1,420,623	SH		DFND		0	0	1,420,623
SI-BONE INC	COM	825704109	27,071	1,218,875	SH		DFND		0	0	1,218,875
SIGHT SCIENCES INC	COM	82657M105	595	33,849	SH		DFND		0	0	33,849
SILVERBOX ENGAGED MERGER CO	COM CL A	82836L101	175	17,211	SH		DFND		0	0	17,211
SILVERCREST METALS INC	COM	828363101	62,943	7,957,451	SH		DFND		0	0	7,957,451
SILVERGATE CAP CORP	CL A	82837P408	31,476	212,387	SH		DFND		0	0	212,387
SINTX TECHNOLOGIES INC	COM NEW	829392307	0	71	SH		DFND		0	0	71
SITEONE LANDSCAPE SUPPLY INC	COM	82982L103	52,451	216,488	SH		DFND		0	0	216,488
SITIME CORP	COM	82982T106	55,643	190,207	SH		DFND		0	0	190,207
SKEENA RES LTD NEW	COM	83056P715	10,003	959,057	SH		DFND		0	0	959,057
SMARTSHEET INC	COM CL A	83200N103	873	11,278	SH		DFND		0	0	11,278
SNAP INC	CL A	83304A106	160,125	3,404,741	SH		DFND		0	0	3,404,741
SNOWFLAKE INC	CL A	833445109	147,714	436,056	SH		DFND		0	0	436,056
SOLID POWER INC	CLASS A COM	83422N105	1,518	173,638	SH		DFND		0	0	173,638
SOMALOGIC INC	CLASS A COM	83444K105	820	70,446	SH		DFND		0	0	70,446
SONENDO INC	COM	835431107	397	68,956	SH		DFND		0	0	68,956
SONOS INC	COM	83570H108	1,715	57,562	SH		DFND		0	0	57,562
SPOTIFY TECHNOLOGY S A	SHS	L8681T102	149,813	640,146	SH		DFND		0	0	640,146
SPROUT SOCIAL INC	COM CL A	85209W109	23,124	254,973	SH		DFND		0	0	254,973
SS&C TECHNOLOGIES HLDGS INC	COM	78467J100	47,389	578,057	SH		DFND		0	0	578,057
STAAR SURGICAL CO	COM PAR $0.01	852312305	24	266	SH		DFND		0	0	266
STARBUCKS CORP	COM	855244109	18,465	157,857	SH		DFND		0	0	157,857
STEM INC	COM	85859N102	20,996	1,106,782	SH		DFND		0	0	1,106,782
STOKE THERAPEUTICS INC	COM	86150R107	25,728	1,072,440	SH		DFND		0	0	1,072,440
STRIDE INC	COM	86333M108	15	462	SH		DFND		0	0	462
SUNNOVA ENERGY INTL INC.	COM	86745K104	663	23,749	SH		DFND		0	0	23,749
SUNRUN INC	COM	86771W105	29,555	861,674	SH		DFND		0	0	861,674
SUNTIMES MEDIA GROUP INC CLASS A COM USD001 NO STOCKHOLDER EQU	COMMONSTOCK	86688Q100	0	650	SH		DFND		0	0	650
SVB FINANCIAL GROUP	COM	78486Q101	15,534	22,904	SH		DFND		0	0	22,904
SVF INVESTMENT CORP 2	CL A SHS	G8601M100	3,563	359,855	SH		DFND		0	0	359,855
SVF INVESTMENT CORP 3	CL A SHS	G8601N108	3,575	357,489	SH		DFND		0	0	357,489
SWEETGREEN INC	COM CL A	87043Q108	752	23,494	SH		DFND		0	0	23,494
TAL EDUCATION GROUP	SPONSORED ADS	874080104	0	29	SH		DFND		0	0	29
TALON THERAPEUTICS CVR NEW	COMMONSTOCK	874CNT108	0	125	SH		DFND		0	0	125
TANDEM DIABETES CARE INC	COM NEW	875372203	115,736	768,906	SH		DFND		0	0	768,906
TELADOC HEALTH INC	COM	87918A105	86,378	940,729	SH		DFND		0	0	940,729
TELESAT CORP	CL A & CL B SHS	879512309	17,359	605,475	SH		DFND		0	0	605,475
TENCENT HOLDINGS LIMITED HKD000002 ISIN KYG875721634 SEDOL BM	COMMONSTOCK	G87572163	11,707	199,805	SH		DFND		0	0	199,805
TESLA INC	COM	88160R101	1,323,135	1,252,044	SH		DFND		0	0	1,252,044
THE BEAUTY HEALTH COMPANY	COM CL A	88331L108	175	7,232	SH		DFND		0	0	7,232
THOR INDS INC	COM	885160101	4,798	46,235	SH		DFND		0	0	46,235
T-MOBILE US INC	COM	872590104	6,826	58,852	SH		DFND		0	0	58,852
TOAST INC	CL A	888787108	133,370	3,842,421	SH		DFND		0	0	3,842,421
TORRID HLDGS INC	COM	89142B107	3,679	372,376	SH		DFND		0	0	372,376
TRACTOR SUPPLY CO	COM	892356106	16	68	SH		DFND		0	0	68
TRANSDIGM GROUP INC	COM	893641100	10,265	16,133	SH		DFND		0	0	16,133
TRUPANION INC	COM	898202106	74,748	566,141	SH		DFND		0	0	566,141
TWILIO INC	CL A	90138F102	96,396	366,053	SH		DFND		0	0	366,053
TWIST BIOSCIENCE CORP	COM	90184D100	3,958	51,140	SH		DFND		0	0	51,140
TWITTER INC	COM	90184L102	5,341	123,587	SH		DFND		0	0	123,587
UBER TECHNOLOGIES INC	COM	90353T100	1,045	24,930	SH		DFND		0	0	24,930
UIPATH INC	CL A	90364P105	5,332	123,625	SH		DFND		0	0	123,625
ULTRAGENYX PHARMACEUTICAL IN	COM	90400D108	1,180	14,034	SH		DFND		0	0	14,034
UNITY SOFTWARE INC	COM	91332U101	84,995	594,410	SH		DFND		0	0	594,410
UPSTART HLDGS INC	COM	91680M107	798	5,276	SH		DFND		0	0	5,276
USERTESTING INC	COM	91734E101	1,056	125,412	SH		DFND		0	0	125,412
USHG ACQUISITION CORP	COM CL A	91748P100	8,201	790,814	SH		DFND		0	0	790,814
VANECK ETF TRUST	GOLD MINERS ETF	92189F106	11,203	349,757	SH		DFND		0	0	349,757
VEEVA SYS INC	CL A COM	922475108	10,983	42,990	SH		DFND		0	0	42,990
VERACYTE INC	COM	92337F107	3,046	73,920	SH		DFND		0	0	73,920
VERIZON COMMUNICATIONS INC	COM	92343V104	7,223	139,019	SH		DFND		0	0	139,019
VIRACTA THERAPEUTICS INC	COM	92765F108	783	214,566	SH		DFND		0	0	214,566
VITAL FARMS INC	COM	92847W103	16,804	930,428	SH		DFND		0	0	930,428
VIZSLA SILVER CORP COM NPV ISIN CA92859G2027 SEDOL BM8VBZ0	COMMONSTOCK	92859G202	3,630	1,518,440	SH		DFND		0	0	1,518,440
VOR BIOPHARMA INC	COM	929033108	734	63,178	SH		DFND		0	0	63,178
VULCAN MATLS CO	COM	929160109	5,528	26,633	SH		DFND		0	0	26,633
WALKME LTD	ORD SHS	M97628107	278	14,171	SH		DFND		0	0	14,171
WHEATON PRECIOUS METALS CORP	COM	962879102	3,304	76,973	SH		DFND		0	0	76,973
WHITING PETE CORP NEW	COM NEW	966387508	27	420	SH		DFND		0	0	420
WILLIAMS SONOMA INC	COM	969904101	7	43	SH		DFND		0	0	43
WILLOW BIOSCIENCES INC COM NPV POST REV SPLIT ISIN CA97111B40	COMMONSTOCK	97111B404	159	447,712	SH		DFND		0	0	447,712
WILLSCOT MOBIL MINI HLDNG CO	COM CL A	971378104	23,784	582,371	SH		DFND		0	0	582,371
WOLFSPEED INC	COM	977852102	1,844	16,502	SH		DFND		0	0	16,502
WORKDAY INC	CL A	98138H101	11,606	42,484	SH		DFND		0	0	42,484
WUXI BIOLOGICS CAYMAN INC USD00000083 144A REG S	COMMONSTOCK	G97008117	98,446	8,292,994	SH		DFND		0	0	8,292,994
XOMETRY INC	CLASS A COM	98423F109	48,806	952,308	SH		DFND		0	0	952,308
XP INC	CL A	G98239109	18,977	660,309	SH		DFND		0	0	660,309
YETI HLDGS INC	COM	98585X104	430	5,191	SH		DFND		0	0	5,191
ZAI LAB LTD	ADR	98887Q104	68,350	1,087,517	SH		DFND		0	0	1,087,517
ZILLOW GROUP INC	CL C CAP STK	98954M200	1,283	20,094	SH		DFND		0	0	20,094
ZIM INTEGRATED SHIPPING SERV	SHS	M9T951109	20	333	SH		DFND		0	0	333
ZOOM VIDEO COMMUNICATIONS IN	CL A	98980L101	157,428	856,004	SH		DFND		0	0	856,004
ZOOMINFO TECHNOLOGIES INC	COM CL A	98980F104	18,637	290,300	SH		DFND		0	0	290,300
ZSCALER INC	COM	98980G102	6,882	21,417	SH		DFND		0	0	21,417
ZUR ROSE GROUP AG CHF3000 ISIN CH0042615283 SEDOL B92M6T7	COMMONSTOCK	H9875C108	29,189	116,872	SH		DFND		0	0	116,872
ZYNGA INC	CL A	98986T108	59	9,295	SH		DFND		0	0	9,295