Gilder Gagnon Howe & Co 13F-HR Quarterly holdings report by institutional manager

The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE

OMB APPROVAL

OMB Number:		3235-0006
Expires:	Oct 31, 2018
Estimated average burden
hours per response:		23.8

COLUMN 1	COLUMN 2	COLUMN 3	COLUMN 4	COLUMN 5			COLUMN 6	COLUMN 7	COLUMN 8
			VALUE	SHRS OR	SH/	PUT/	INVESTMENT	OTHER	VOTING AUTHORITY
NAME OF ISSUER	TITLE OF CLASS	CUSIP	(x$1000)	PRN AMT	PRN	CALL	DISCRETION	MANAGER	SOLE	SHARED	NONE
2U INC COM USD0.001	COM	90214J101	144,933	2,045,635	SH		DFND		0	0	2,045,635
ABIOMED INC COM USD0.01	COM	003654100	62,420	218,564	SH		DFND		0	0	218,564
ACACIA COMMUNICATIONS INC COM	COM	00401C108	997	17,385	SH		DFND		0	0	17,385
ACTIVISION BLIZZARD INC COM USD0.000001	COM	00507V109	3,976	87,329	SH		DFND		0	0	87,329
ADESTO TECHNOLOGIES CORP COM	COM	00687D101	9,487	1,568,132	SH		DFND		0	0	1,568,132
ADOBE INC COM	COM	00724F101	45,076	169,148	SH		DFND		0	0	169,148
ADVANCED MICRO DEVICES INC COM	COM	007903107	526	20,595	SH		DFND		0	0	20,595
ADYEN NV 144A	COM	N3501V104	84,527	107,850	SH		DFND		0	0	107,850
AEROJET ROCKETDYNE HLDGS INC COM	COM	007800105	20,446	575,460	SH		DFND		0	0	575,460
ALASKA COMM SYS GRP INC	COM	01167P101	3,722	1,938,300	SH		DFND		0	0	1,938,300
ALDEYRA THERAPEUTICS USD0.001	COM	01438T106	1,974	218,636	SH		DFND		0	0	218,636
ALECTOR INC COM	COM	014442107	4,088	218,385	SH		DFND		0	0	218,385
ALIBABA GROUP HOLDING LTD SPON ADS EACH REP ONE ORD SHS	COM	01609W102	74,343	407,469	SH		DFND		0	0	407,469
ALLAKOS INC COM	COM	01671P100	1,313	32,417	SH		DFND		0	0	32,417
ALLEGIANT TRAVEL COMPANY COM USD0.001	COM	01748X102	12,243	94,561	SH		DFND		0	0	94,561
ALLOGENE THERAPEUTICS INC COM	COM	019770106	63	2,182	SH		DFND		0	0	2,182
ALNYLAM PHARMACEUTICALS INC	COM	02043Q107	92,307	987,770	SH		DFND		0	0	987,770
ALPHABET INC CAP STK CL A	COM	02079K305	53,639	45,577	SH		DFND		0	0	45,577
ALPHABET INC CAP STK CL C	COM	02079K107	60,142	51,258	SH		DFND		0	0	51,258
ALTIUS MINERALS CORP COM ISIN #CA0209361009 SEDOL #2122355	COM	020936100	7,022	732,928	SH		DFND		0	0	732,928
ALTUS MIDSTREAM CO CL A	COM	02215L100	3,221	545,938	SH		DFND		0	0	545,938
AMAZON.COM INC	COM	023135106	443,595	249,106	SH		DFND		0	0	249,106
AMBER ROAD INC COM USD0.001	COM	02318Y108	625	72,030	SH		DFND		0	0	72,030
AMERICAN EAGLE OUTFITTERS INC COM	COM	02553E106	65,214	2,941,559	SH		DFND		0	0	2,941,559
AMERICAN TOWER CORP COM USD0.01	COM	03027X100	16,414	83,294	SH		DFND		0	0	83,294
AMYRIS INC COM NEW	COM	03236M200	113	54,044	SH		DFND		0	0	54,044
ANAPLAN INC COM	COM	03272L108	191	4,849	SH		DFND		0	0	4,849
APACHE CORP COM USD0.0001 CL A	COM	037411105	7,188	207,381	SH		DFND		0	0	207,381
APPFOLIO INC COM CL A	COM	03783C100	147	1,852	SH		DFND		0	0	1,852
APPIAN CORP CL A	COM	03782L101	5,535	160,771	SH		DFND		0	0	160,771
APPLE INC COM USD0.00001	COM	037833100	5,279	27,792	SH		DFND		0	0	27,792
APPLIED OPTOELECTRONICS INC COM	COM	03823U102	93	7,637	SH		DFND		0	0	7,637
AQUANTIA CORP COM	COM	03842Q108	13,890	1,533,167	SH		DFND		0	0	1,533,167
ARCO PLATFORM LTD COM USD0.00005 CL A	COM	G04553106	11,167	345,835	SH		DFND		0	0	345,835
ARISTA NETWORKS INC COM USD0.0001	COM	040413106	134,392	427,373	SH		DFND		0	0	427,373
ARRAY BIOPHARMA INC	COM	04269X105	29,776	1,221,310	SH		DFND		0	0	1,221,310
ASV HLDGS INC COM	COM	00215L104	2,117	769,914	SH		DFND		0	0	769,914
AT HOME GROUP INC COM	COM	04650Y100	8,268	462,943	SH		DFND		0	0	462,943
ATLASSIAN CORPORATION PLC COM USD0.1 CL A	COM	G06242104	21,542	191,676	SH		DFND		0	0	191,676
AUDENTES THERAPEUTICS INC COM	COM	05070R104	63,206	1,619,831	SH		DFND		0	0	1,619,831
AUTO TRADER GROUP PLC ORD GBP0.01 144A REG S ISIN #GB00BVYVFW23	COM	G06708104	6,008	883,905	SH		DFND		0	0	883,905
AUTODESK INC COM	COM	052769106	122,854	788,435	SH		DFND		0	0	788,435
AVEDRO INC COM	COM	05355N109	209	17,058	SH		DFND		0	0	17,058
AXIS BANK GDR EACH REPR 1 INR10 REG S ISIN #US05462W1099 SEDOL #	COM	05462W109	843	15,085	SH		DFND		0	0	15,085
AXOGEN INC COM	COM	05463X106	9,305	441,851	SH		DFND		0	0	441,851
AZUL SA SPON ADR EACH REP 3 PFD SHS	COM	05501U106	104,364	3,572,880	SH		DFND		0	0	3,572,880
AZURRX BIOPHARMA INC COM	COM	05502L105	1,311	541,536	SH		DFND		0	0	541,536
BANDWIDTH INC COM CL A	COM	05988J103	36,939	551,652	SH		DFND		0	0	551,652
BARCLAYS BANK PLC IPATH B SHRT TERM	COM	06746P621	4,234	144,691	SH		DFND		0	0	144,691
BERKLEY W R CORP COM	COM	084423102	5,073	59,876	SH		DFND		0	0	59,876
BERKSHIRE HATHAWAY INC COM USD0.0033 CLASS B	COM	084670702	271	1,351	SH		DFND		0	0	1,351
BIOSCRIP INC	COM	09069N108	27,224	13,611,958	SH		DFND		0	0	13,611,958
BLACK KNIGHT INC COM	COM	09215C105	5,231	95,975	SH		DFND		0	0	95,975
BLUEBIRD BIO INC COM	COM	09609G100	6,125	38,929	SH		DFND		0	0	38,929
BOSTON SCIENTIFIC CORP	COM	101137107	1,607	41,861	SH		DFND		0	0	41,861
BRIGHTCOVE INC COM USD0.001	COM	10921T101	251	29,834	SH		DFND		0	0	29,834
CALIX INC COM	COM	13100M509	981	127,409	SH		DFND		0	0	127,409
CALYXT INC COM	COM	13173L107	172	9,783	SH		DFND		0	0	9,783
CAREDX INC COM	COM	14167L103	3,769	119,565	SH		DFND		0	0	119,565
CARL ZEISS MEDITEC AG NPV ISIN #DE0005313704 SEDOL #5922961	COM	D14895102	1,446	17,359	SH		DFND		0	0	17,359
CARROLS RESTAURANT GROUP INC COM	COM	14574X104	3,869	388,058	SH		DFND		0	0	388,058
CARVANA CO CL A	COM	146869102	25,741	443,358	SH		DFND		0	0	443,358
CASA SYS INC COM	COM	14713L102	387	46,577	SH		DFND		0	0	46,577
CATAPULT GROUP INTERNATIONAL ISIN #AU000000CAT9 SEDOL #BTL0Y76	COM	Q2159P101	141	211,309	SH		DFND		0	0	211,309
CHARLOTTES WEB HOLDINGS INC COM NPV	COM	16106R109	1,444	72,376	SH		DFND		0	0	72,376
CHART INDUSTRIES INC COM USD0.01	COM	16115Q308	11,780	130,142	SH		DFND		0	0	130,142
CHEGG INC COM USD0.001	COM	163092109	187,739	4,924,952	SH		DFND		0	0	4,924,952
CHIPOTLE MEXICAN GRILL INC COM	COM	169656105	31	43	SH		DFND		0	0	43
CODEXIS INC COM USD0.0001	COM	192005106	51,107	2,489,389	SH		DFND		0	0	2,489,389
CONSTRUCTION PARTNERS INC COM CL A	COM	21044C107	729	57,055	SH		DFND		0	0	57,055
COUPA SOFTWARE INC COM	COM	22266L106	24,872	273,376	SH		DFND		0	0	273,376
COVANTA HLDG CORP COM	COM	22282E102	8,102	468,071	SH		DFND		0	0	468,071
CRIMSON WINE GROUP COM USD0.01	COM	22662X100	658	79,997	SH		DFND		0	0	79,997
DEERE & COMPANY	COM	244199105	16	100	SH		DFND		0	0	100
DENALI THERAPEUTICS INC COM	COM	24823R105	14	596	SH		DFND		0	0	596
DEXCOM INC	COM	252131107	80,960	679,765	SH		DFND		0	0	679,765
DIGI INTL INC COM	COM	253798102	5,926	467,720	SH		DFND		0	0	467,720
DISNEY WALT CO	COM	254687106	131	1,176	SH		DFND		0	0	1,176
DOCUSIGN INC COM	COM	256163106	3,041	58,670	SH		DFND		0	0	58,670
EHEALTH INC COM	COM	28238P109	34,493	553,298	SH		DFND		0	0	553,298
ELASTIC N V COM EUR0.01	COM	N14506104	9,459	118,428	SH		DFND		0	0	118,428
ELECTRONIC ARTS	COM	285512109	187	1,838	SH		DFND		0	0	1,838
ENPHASE ENERGY INC COM USD0.00001	COM	29355A107	41,667	4,514,342	SH		DFND		0	0	4,514,342
ENTERCOM COMMUNICATIONS CORP CL A	COM	293639100	5,909	1,125,574	SH		DFND		0	0	1,125,574
EPAM SYS INC COM USD0.001	COM	29414B104	97,568	576,883	SH		DFND		0	0	576,883
EROS INTERNATIONAL COM GBP0.30	COM	G3788M114	19,226	2,103,464	SH		DFND		0	0	2,103,464
ESPERION THERAPEUTICS INC COM USD0.001	COM	29664W105	45	1,132	SH		DFND		0	0	1,132
ETSY INC COM	COM	29786A106	242,827	3,612,418	SH		DFND		0	0	3,612,418
EVERBRIDGE INC COM	COM	29978A104	35,823	477,570	SH		DFND		0	0	477,570
EXACT SCIENCES CORP	COM	30063P105	173,707	2,005,394	SH		DFND		0	0	2,005,394
EXTRACTION OIL AND GAS INC COM	COM	30227M105	633	149,568	SH		DFND		0	0	149,568
FACEBOOK INC-CLASS A	COM	30303M102	179,493	1,076,808	SH		DFND		0	0	1,076,808
FARFETCH LTD COM USD0.04 CLASS A	COM	30744W107	93,882	3,488,749	SH		DFND		0	0	3,488,749
FIVE BELOW INC COM	COM	33829M101	87,677	705,650	SH		DFND		0	0	705,650
FLEX LNG LTD (BM) USD0.10 ISIN #BMG359472021 SEDOL #BJJMGB2	COM	G35947202	6,604	510,490	SH		DFND		0	0	510,490
FLEXION THERAPEUTICS INC COM	COM	33938J106	17,003	1,362,386	SH		DFND		0	0	1,362,386
FLOOR &DECOR HLDGS INC CL A	COM	339750101	25,050	607,711	SH		DFND		0	0	607,711
FORESCOUT TECHNOLOGIES INC COM	COM	34553D101	17,935	427,929	SH		DFND		0	0	427,929
FRANCO NEVADA CORP COM ISIN #CA3518581051 SEDOL #B29NF31	COM	351858105	5,817	77,503	SH		DFND		0	0	77,503
FRESHPET INC COM	COM	358039105	108,750	2,571,525	SH		DFND		0	0	2,571,525
FUSION CONNECT INC COM	COM	36116X102	46	35,000	SH		DFND		0	0	35,000
GALAPAGOS NV NPV ISIN #BE0003818359 SEDOL #B07Q2V5	COM	B44170106	47,633	408,289	SH		DFND		0	0	408,289
GASLOG LTD COM USD0.01	COM	G37585109	3,121	178,767	SH		DFND		0	0	178,767
GEOPARK LIMITED COM USD0.001	COM	G38327105	3,834	221,722	SH		DFND		0	0	221,722
GLAUKOS CORP COM	COM	377322102	97,653	1,246,053	SH		DFND		0	0	1,246,053
GLOBANT SA USD1.20	COM	L44385109	55,364	775,413	SH		DFND		0	0	775,413
GOGO INC COM	COM	38046C109	316	70,320	SH		DFND		0	0	70,320
GOL LINHAS AEREAS INTELIGENTES SA PFD	COM	38045R206	5,584	427,916	SH		DFND		0	0	427,916
GOLAR LNG LIMITED COM STK USD1.00	COM	G9456A100	10,026	475,405	SH		DFND		0	0	475,405
GOLDMAN SACHS GROUP INC COM USD0.01	COM	38141G104	74,519	388,142	SH		DFND		0	0	388,142
GOOSEHEAD INS INC COM CL A	COM	38267D109	43,801	1,571,037	SH		DFND		0	0	1,571,037
GRACE(W.R.)&CO COM USD0.01	COM	38388F108	17,232	220,806	SH		DFND		0	0	220,806
GRUPO FINANCIERO GALICIA SA SPON ADR EACH REP 10 CL B SHS	COM	399909100	1,972	77,268	SH		DFND		0	0	77,268
GTT COMMUNICATIONS INC COM USD0.0001	COM	362393100	68,837	1,983,779	SH		DFND		0	0	1,983,779
GUARDANT HEALTH INC COM	COM	40131M109	53	686	SH		DFND		0	0	686
GUIDEWIRE SOFTWARE INC COM USD0.0001	COM	40171V100	488	5,021	SH		DFND		0	0	5,021
HDFC BANK LTD SPON ADS EACH REP 3 ORD SHS	COM	40415F101	49,005	422,789	SH		DFND		0	0	422,789
HEALTHEQUITY INC COM	COM	42226A107	5,545	74,949	SH		DFND		0	0	74,949
HEICO CORP	COM	422806109	125	1,322	SH		DFND		0	0	1,322
HEICO CORP COM USD0.01	COM	422806208	210	2,500	SH		DFND		0	0	2,500
HOWARD HUGHES CORP COM	COM	44267D107	246	2,239	SH		DFND		0	0	2,239
HUBSPOT INC COM	COM	443573100	130,197	783,329	SH		DFND		0	0	783,329
ICICI BANK LIMITED SPON ADR EACH REPR 2 ORD SHS	COM	45104G104	4,246	370,539	SH		DFND		0	0	370,539
ILLUMINA INC COM USD0.001	COM	452327109	32,772	105,480	SH		DFND		0	0	105,480
IMPINJ INC COM	COM	453204109	778	46,410	SH		DFND		0	0	46,410
INFINERA CORPORATION COM	COM	45667G103	472	108,682	SH		DFND		0	0	108,682
INSPIRE MED SYS INC COM	COM	457730109	8,495	149,612	SH		DFND		0	0	149,612
INSULET CORP COM	COM	45784P101	2,159	22,709	SH		DFND		0	0	22,709
INTUITIVE SURGICAL INC COM NEW	COM	46120E602	116,201	203,655	SH		DFND		0	0	203,655
INVITAE CORP COM	COM	46185L103	129,513	5,530,037	SH		DFND		0	0	5,530,037
IQIYI INC SPON EACH ADS REP 7 ORD SHS CLASS A	COM	46267X108	50	2,097	SH		DFND		0	0	2,097
IRHYTHM TECHNOLOGIES INC COM	COM	450056106	8,378	111,761	SH		DFND		0	0	111,761
IROBOT CORP COM	COM	462726100	99,376	844,390	SH		DFND		0	0	844,390
JD.COM INC SPON ADS EACH REPR 2 ORD SHS CLASS A	COM	47215P106	24,815	823,060	SH		DFND		0	0	823,060
JPMORGAN CHASE &CO. COM USD1.00	COM	46625H100	7,608	75,152	SH		DFND		0	0	75,152
KANSAS CITY SOUTHERN COM	COM	485170302	4,640	40,005	SH		DFND		0	0	40,005
KB HOME COM	COM	48666K109	191	7,908	SH		DFND		0	0	7,908
KIRKLAND LAKE GOLD COM NPV ISIN #CA49741E1007 SEDOL #BD4G349	COM	49741E100	12,330	405,465	SH		DFND		0	0	405,465
KORNIT DIGITAL LTD ORD ILS0.01	COM	M6372Q113	24,737	1,039,382	SH		DFND		0	0	1,039,382
LGI HOMES INC COM	COM	50187T106	86,056	1,428,557	SH		DFND		0	0	1,428,557
LHC GROUP INC COM	COM	50187A107	10,799	97,407	SH		DFND		0	0	97,407
LIBERTY MEDIA CORP DELAWARE COM A BRAVES GRP	COM	531229706	4,679	167,471	SH		DFND		0	0	167,471
LIBERTY MEDIA CORP DELAWARE COM C BRAVES GRP	COM	531229888	17,273	622,017	SH		DFND		0	0	622,017
LIBERTY MEDIA CORP DELAWARE COM SER C FRMLA	COM	531229854	4,967	141,698	SH		DFND		0	0	141,698
LILIS ENERGY INC COM NEW	COM	532403201	94	80,000	SH		DFND		0	0	80,000
LIVEPERSON INC COM USD0.001	COM	538146101	98,138	3,381,722	SH		DFND		0	0	3,381,722
LONZA GROUP AG-REG ISIN #CH0013841017 SEDOL #7333378	COM	H50524133	34,312	110,660	SH		DFND		0	0	110,660
LOVESAC COMPANY COM	COM	54738L109	16,298	586,049	SH		DFND		0	0	586,049
LULULEMON ATHLETICA INC COM USD0.005	COM	550021109	5,184	31,632	SH		DFND		0	0	31,632
LUMENTUM HLDGS INC COM	COM	55024U109	1,202	21,254	SH		DFND		0	0	21,254
LYFT INC CL A COM	COM	55087P104	42,175	538,707	SH		DFND		0	0	538,707
MADISON SQUARE GARDEN CO NEW CL A	COM	55825T103	7,314	24,950	SH		DFND		0	0	24,950
MAG SILVER CORP COM NPV ISIN #CA55903Q1046 SEDOL #2581332	COM	55903Q104	17,145	1,608,390	SH		DFND		0	0	1,608,390
MAGENTA THERAPEUTICS INC COM	COM	55910K108	30,127	1,829,228	SH		DFND		0	0	1,829,228
MAGNOLIA OIL &GAS CORP CL A	COM	559663109	7,546	628,872	SH		DFND		0	0	628,872
MAKEMYTRIP LTD USD0.0005	COM	V5633W109	2,770	100,378	SH		DFND		0	0	100,378
MARTIN MARIETTA MATERIALS INC COM USD0.01	COM	573284106	92,039	457,498	SH		DFND		0	0	457,498
MASTERCARD INC CL A	COM	57636Q104	22,268	94,578	SH		DFND		0	0	94,578
MATCH GROUP INC COM	COM	57665R106	62,917	1,111,407	SH		DFND		0	0	1,111,407
MERCADOLIBRE INC COM USD0.001	COM	58733R102	81,931	161,368	SH		DFND		0	0	161,368
MERCURY SYS INC COM	COM	589378108	215	3,350	SH		DFND		0	0	3,350
MESA AIR GROUP INC COM NEW	COM	590479135	7,718	925,438	SH		DFND		0	0	925,438
MICROSOFT CORP	COM	594918104	68,497	580,778	SH		DFND		0	0	580,778
MIMECAST LIMITED COM USD0.012	COM	G14838109	1,584	33,456	SH		DFND		0	0	33,456
MISONIX INC	COM	604871103	3,960	205,906	SH		DFND		0	0	205,906
MOLECULAR TEMPLATES INC COM	COM	608550109	5,691	979,502	SH		DFND		0	0	979,502
MONGODB INC CL A	COM	60937P106	199,641	1,357,916	SH		DFND		0	0	1,357,916
MONOLITHIC PWR SYS INC COM	COM	609839105	13,705	101,152	SH		DFND		0	0	101,152
NETFLIX COM INC COM	COM	64110L106	561,517	1,574,818	SH		DFND		0	0	1,574,818
NEW PACIFIC METALS CORP COM NPV ISIN #CA6478241012 SEDOL #BF4CP8	COM	647824101	2,225	1,254,245	SH		DFND		0	0	1,254,245
NEW RELIC INC COM	COM	64829B100	10,355	104,916	SH		DFND		0	0	104,916
NEW YORK TIMES CO CL A	COM	650111107	171,241	5,212,809	SH		DFND		0	0	5,212,809
NINTENDO CO LTD ADR(8 CNV INTO 1 ORD)NPV	COM	654445303	16,902	474,214	SH		DFND		0	0	474,214
NIU TECHNOLOGIES SPON ADS EACH REP 2 ORD SHS CL A	COM	65481N100	24	2,910	SH		DFND		0	0	2,910
NOBLE MIDSTREAM PARTNERS LP COM UNIT REPST	COM	65506L105	37	1,014	SH		DFND		0	0	1,014
NRG ENERGY INC COM NEW	COM	629377508	624	14,698	SH		DFND		0	0	14,698
NUVECTRA CORP COM	COM	67075N108	11,266	1,023,223	SH		DFND		0	0	1,023,223
NV5 GLOBAL INC COM	COM	62945V109	8,502	143,233	SH		DFND		0	0	143,233
NVIDIA CORP	COM	67066G104	32,912	183,292	SH		DFND		0	0	183,292
OCADO GROUP PLC ORD GBP0.02 ISIN #GB00B3MBS747 SEDOL #B3MBS74	COM	G6718L106	253,430	14,191,164	SH		DFND		0	0	14,191,164
OKTA INC CL A	COM	679295105	173,003	2,091,177	SH		DFND		0	0	2,091,177
OVERSTOCK COM INC DEL COM	COM	690370101	27	1,623	SH		DFND		0	0	1,623
PALO ALTO NETWORKS INC COM USD0.0001	COM	697435105	18,187	74,879	SH		DFND		0	0	74,879
PARAMOUNT RESOURCES LIMITED COM NPV CLASS A ISIN #CA6993202069 S	COM	699320206	909	170,502	SH		DFND		0	0	170,502
PAYPAL HLDGS INC COM	COM	70450Y103	23,140	222,845	SH		DFND		0	0	222,845
PDF SOLUTIONS INC	COM	693282105	659	53,354	SH		DFND		0	0	53,354
PDVWIRELESS INC COM	COM	69290R104	312	8,865	SH		DFND		0	0	8,865
PENSKE AUTOMOTIVE GROUP INC	COM	70959W103	3,175	71,109	SH		DFND		0	0	71,109
PENUMBRA INC COM	COM	70975L107	6,776	46,094	SH		DFND		0	0	46,094
PINDUODUO INC SPON ADS EACH REP 4 ORD SHS	COM	722304102	129	5,200	SH		DFND		0	0	5,200
PIVOTAL SOFTWARE INC COM CL A	COM	72582H107	6,882	330,075	SH		DFND		0	0	330,075
PLANET FITNESS INC CL A	COM	72703H101	3,094	45,018	SH		DFND		0	0	45,018
PLURALSIGHT INC COM CL A	COM	72941B106	4,697	147,989	SH		DFND		0	0	147,989
POOL CORP COM	COM	73278L105	63,593	385,482	SH		DFND		0	0	385,482
PROOFPOINT INC COM USD0.0001	COM	743424103	6,064	49,935	SH		DFND		0	0	49,935
Q2 HLDGS INC COM	COM	74736L109	21,645	312,511	SH		DFND		0	0	312,511
QUANTERIX CORP COM	COM	74766Q101	25,484	986,587	SH		DFND		0	0	986,587
R1 RCM INC COM	COM	749397105	5,401	558,487	SH		DFND		0	0	558,487
REECE LIMITED NPV ISIN #AU000000REH4 SEDOL #6728801	COM	Q80528138	4,104	585,888	SH		DFND		0	0	585,888
RELIANCE INDUSTRIES SPON GDR EACH REP 2 ORD SHS 144A ISIN #US759	COM	ZZC27DZQ8	580	14,454	SH		DFND		0	0	14,454
RIGHTMOVE ORD GBP0.001 ISIN #GB00BGDT3G23 SEDOL #BGDT3G2	COM	G7565D106	17,326	2,607,187	SH		DFND		0	0	2,607,187
RINGCENTRAL INC-CLASS A	COM	76680R206	230,504	2,138,253	SH		DFND		0	0	2,138,253
ROKU INC COM CL A	COM	77543R102	228,477	3,541,731	SH		DFND		0	0	3,541,731
ROYAL GOLD INC COM ISIN #US7802871084 SEDOL #2430553	COM	780287108	18	198	SH		DFND		0	0	198
SAFETY INS GROUP INC	COM	78648T100	411	4,720	SH		DFND		0	0	4,720
SALESFORCE.COM INC COM USD0.001	COM	79466L302	99,374	627,482	SH		DFND		0	0	627,482
SAREPTA THERAPEUTICS INC COM	COM	803607100	118,281	992,371	SH		DFND		0	0	992,371
SEASPINE HLDGS CORP COM	COM	81255T108	361	23,940	SH		DFND		0	0	23,940
SEMLER SCIENTIFIC INC COM USD0.001	COM	81684M104	4,043	94,539	SH		DFND		0	0	94,539
SENESTECH INC COM	COM	81720R109	1,511	1,238,750	SH		DFND		0	0	1,238,750
SENSEONICS HLDGS INC COM	COM	81727U105	43,469	17,742,518	SH		DFND		0	0	17,742,518
SERVICENOW INC COM USD0.001	COM	81762P102	34,923	141,683	SH		DFND		0	0	141,683
SHAKE SHACK INC CL A	COM	819047101	119,736	2,024,283	SH		DFND		0	0	2,024,283
SHERWIN WILLIAMS CO	COM	824348106	912	2,117	SH		DFND		0	0	2,117
SHOCKWAVE MED INC COM	COM	82489T104	44,601	1,332,559	SH		DFND		0	0	1,332,559
SHOPIFY INC COM NPV CL A ISIN #CA82509L1076 SEDOL #BX865C7	COM	82509L107	59,354	287,263	SH		DFND		0	0	287,263
SHOTSPOTTER INC COM	COM	82536T107	84,019	2,176,651	SH		DFND		0	0	2,176,651
SI BONE INC COM	COM	825704109	6,682	354,663	SH		DFND		0	0	354,663
SIENTRA INC COM USD0.01	COM	82621J105	3,525	410,827	SH		DFND		0	0	410,827
SILVERCREST METALS INC COM NPV ISIN #CA8283631015 SEDOL #BYVY3D2	COM	828363101	16,648	5,083,284	SH		DFND		0	0	5,083,284
SITEONE LANDSCAPE SUPPLY INC COM	COM	82982L103	17,846	312,263	SH		DFND		0	0	312,263
SIX FLAGS ENTMT CORP NEW COM	COM	83001A102	4,136	83,816	SH		DFND		0	0	83,816
SKYLINE CHAMPION CORPORATION COM	COM	830830105	13	674	SH		DFND		0	0	674
SNAP INC CL A	COM	83304A106	1,600	145,175	SH		DFND		0	0	145,175
SOCIAL CAP HEDOSOPHIA HLDGS CORP UNIT 1 CL A & 1/3 WT EXP ISIN #	COM	G8250R111	1,812	175,605	SH		DFND		0	0	175,605
SOLARIS OILFIELD INFRSTR INC COM CL A	COM	83418M103	10,517	639,703	SH		DFND		0	0	639,703
SPLUNK INC COM USD0.001	COM	848637104	6,105	48,995	SH		DFND		0	0	48,995
SPOTIFY TECHNOLOGY S.A. COM EUR0.000625	COM	L8681T102	240	1,730	SH		DFND		0	0	1,730
SQUARE INC CL A	COM	852234103	136,213	1,818,106	SH		DFND		0	0	1,818,106
SS&C TECHNOLOGIES HLDGS INC COM	COM	78467J100	61,814	970,538	SH		DFND		0	0	970,538
STAAR SURGICAL CO COM NEW PAR $0.01	COM	852312305	4,098	119,869	SH		DFND		0	0	119,869
STAR BULK CARRIERS CORP COM USD0.01(POST REV SPLIT)	COM	Y8162K204	631	95,902	SH		DFND		0	0	95,902
STARS GROUP INC(THE) COM NPV ISIN #CA85570W1005 SEDOL #BDG1MJ0	COM	85570W100	488	27,852	SH		DFND		0	0	27,852
STITCH FIX INC COM CL A	COM	860897107	7,799	276,284	SH		DFND		0	0	276,284
STONECO LTD COM USD0.000079365 CLASS A	COM	G85158106	626	15,218	SH		DFND		0	0	15,218
SUNRUN INC COM	COM	86771W105	589	41,859	SH		DFND		0	0	41,859
SVB FINL GROUP	COM	78486Q101	13,781	61,975	SH		DFND		0	0	61,975
T MOBILE US INC COM USD0.00001	COM	872590104	89,559	1,296,081	SH		DFND		0	0	1,296,081
TACTILE SYS TECHNOLOGY INC COM	COM	87357P100	5,879	111,515	SH		DFND		0	0	111,515
TAKEAWAY.COM N.V. EUR0.04 144A ISIN #NL0012015705 SEDOL #BYQ7HZ6	COM	N84437107	226	2,973	SH		DFND		0	0	2,973
TAL EDUCATION GROUP SPON ADS EACH REP 0.3333 CL A ORD SHS	COM	874080104	44,408	1,230,829	SH		DFND		0	0	1,230,829
TALEND SA ADS EACH REP 1 ORD SHS	COM	874224207	1,753	34,669	SH		DFND		0	0	34,669
TANDEM DIABETES CARE INC COM NEW	COM	875372203	34,078	536,654	SH		DFND		0	0	536,654
TELADOC HEALTH INC COM	COM	87918A105	82,269	1,479,659	SH		DFND		0	0	1,479,659
TENCENT HOLDINGS LIMITED HKD0.00002 ISIN #KYG875721634 SEDOL #BM	COM	G87572163	64,797	1,409,006	SH		DFND		0	0	1,409,006
TESLA INC COM	COM	88160R101	154,707	552,801	SH		DFND		0	0	552,801
THE A2 MILK COMPANY LTD NPV ISIN #NZATME0002S8 SEDOL #BWSRTS7	COM	ZZCXTSUT2	18,558	1,918,118	SH		DFND		0	0	1,918,118
THOR INDS INC	COM	885160101	3,129	50,165	SH		DFND		0	0	50,165
TMAC RESOURCES INC COM NPV ISIN #CA8725771015 SEDOL #BYT0622	COM	872577101	1,077	330,611	SH		DFND		0	0	330,611
TRANSDIGM GROUP INC COM	COM	893641100	7,303	16,086	SH		DFND		0	0	16,086
TRUPANION INC COM USD0.00001	COM	898202106	5,702	174,169	SH		DFND		0	0	174,169
TWILIO INC CL A	COM	90138F102	8,359	64,710	SH		DFND		0	0	64,710
TWITTER INC COM USD0.000005	COM	90184L102	98,995	3,010,798	SH		DFND		0	0	3,010,798
UBIQUITI NETWORKS INC COM USD0.001	COM	90347A100	228	1,525	SH		DFND		0	0	1,525
UNDER ARMOUR INC COM STK USD0.000333 CLASS A	COM	904311107	210	9,920	SH		DFND		0	0	9,920
UNITY BIOTECHNOLOGY INC COM	COM	91381U101	151	18,598	SH		DFND		0	0	18,598
USA TECHNOLOGIES INC COM NO PAR	COM	90328S500	57	13,633	SH		DFND		0	0	13,633
VANECK VECTORS ETF TR GOLD MINERS ETF	COM	92189F106	10,095	450,246	SH		DFND		0	0	450,246
VAPOTHERM INC COM	COM	922107107	1,328	67,584	SH		DFND		0	0	67,584
VEEVA SYS INC CL A COM	COM	922475108	17,942	141,430	SH		DFND		0	0	141,430
VERACYTE INC COM	COM	92337F107	86,400	3,453,224	SH		DFND		0	0	3,453,224
VERIZON COMMUNICATIONS	COM	92343V104	12,743	215,501	SH		DFND		0	0	215,501
VERRICA PHARMACEUTICALS INC COM	COM	92511W108	2,531	234,116	SH		DFND		0	0	234,116
VIEWRAY INC COM	COM	92672L107	4,344	587,784	SH		DFND		0	0	587,784
VULCAN MATERIALS CO	COM	929160109	4,921	41,566	SH		DFND		0	0	41,566
WHEATON PRECIOUS METALS CORP COM NPV ISIN #CA9628791027 SEDOL #B	COM	962879102	1,926	80,843	SH		DFND		0	0	80,843
WILLSCOT CORP COM	COM	971375126	992	89,433	SH		DFND		0	0	89,433
WORKDAY INC COM USD0.001 CL A	COM	98138H101	30,828	159,855	SH		DFND		0	0	159,855
WORLD WRESTLING ENTERTAINMENT INC CL A	COM	98156Q108	114,686	1,321,573	SH		DFND		0	0	1,321,573
WUXI BIOLOGICS (CAYMAN) INC USD0.000025 144A REG S ISIN #KYG9700	COM	G97008109	14,267	1,466,856	SH		DFND		0	0	1,466,856
XILINX INC	COM	983919101	30,857	243,374	SH		DFND		0	0	243,374
ZAI LAB LIMITED ADS EACH REP 1 ORD SHS	COM	98887Q104	26,652	903,159	SH		DFND		0	0	903,159
ZAYO GROUP HLDGS INC COM	COM	98919V105	11,395	400,946	SH		DFND		0	0	400,946
ZENDESK INC COM USD0.01	COM	98936J101	12,001	141,192	SH		DFND		0	0	141,192
ZILLOW GROUP INC CL A	COM	98954M101	361	10,554	SH		DFND		0	0	10,554
ZUORA INC COM CL A	COM	98983V106	39,578	1,975,935	SH		DFND		0	0	1,975,935