Gilder Gagnon Howe & Co 13F-HR Quarterly holdings report by institutional manager

The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE

OMB APPROVAL

OMB Number:		3235-0006
Expires:	Oct 31, 2018
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COLUMN 1	COLUMN 2	COLUMN 3	COLUMN 4	COLUMN 5			COLUMN 6	COLUMN 7	COLUMN 8
			VALUE	SHRS OR	SH/	PUT/	INVESTMENT	OTHER	VOTING AUTHORITY
NAME OF ISSUER	TITLE OF CLASS	CUSIP	(x$1000)	PRN AMT	PRN	CALL	DISCRETION	MANAGER	SOLE	SHARED	NONE
2U INC COM USD0.001	COM	90214J101	37,230	989,096	SH		DFND		0	0	989,096
ABIOMED INC COM USD0.01	COM	003654100	44,045	169,084	SH		DFND		0	0	169,084
ACACIA COMMUNICATIONS INC COM	COM	00401C108	819	17,377	SH		DFND		0	0	17,377
ACTIVISION BLIZZARD INC COM USD0.000001	COM	00507V109	3,475	73,623	SH		DFND		0	0	73,623
ADAPTIVE BIOTECHNOLOGIES CORP COM	COM	00650F109	28,581	591,749	SH		DFND		0	0	591,749
ADESTO TECHNOLOGIES CORP COM	COM	00687D101	12,608	1,547,003	SH		DFND		0	0	1,547,003
ADOBE INC COM	COM	00724F101	49,153	166,817	SH		DFND		0	0	166,817
ADYEN NV 144A	COM	N3501V104	83,091	107,521	SH		DFND		0	0	107,521
AEROJET ROCKETDYNE HLDGS INC COM	COM	007800105	30,871	689,542	SH		DFND		0	0	689,542
AFTERPAY TOUCH GROUP LTD ISIN #AU000000APT1 SEDOL #BF5L8B9	COM	Q3583G105	3,295	187,284	SH		DFND		0	0	187,284
ALASKA COMM SYS GRP INC	COM	01167P101	3,055	1,786,765	SH		DFND		0	0	1,786,765
ALDEYRA THERAPEUTICS USD0.001	COM	01438T106	1,308	218,042	SH		DFND		0	0	218,042
ALIBABA GROUP HOLDING LTD SPON ADS EACH REP ONE ORD SHS	COM	01609W102	68,759	405,776	SH		DFND		0	0	405,776
ALLAKOS INC COM	COM	01671P100	1,401	32,335	SH		DFND		0	0	32,335
ALLEGIANT TRAVEL COMPANY COM USD0.001	COM	01748X102	13,401	93,390	SH		DFND		0	0	93,390
ALLOGENE THERAPEUTICS INC COM	COM	019770106	59	2,182	SH		DFND		0	0	2,182
ALNYLAM PHARMACEUTICALS INC	COM	02043Q107	70,951	977,819	SH		DFND		0	0	977,819
ALPHABET INC CAP STK CL A	COM	02079K305	48,933	45,191	SH		DFND		0	0	45,191
ALPHABET INC CAP STK CL C	COM	02079K107	55,235	51,100	SH		DFND		0	0	51,100
ALTIUS MINERALS CORP COM ISIN #CA0209361009 SEDOL #2122355	COM	020936100	7,103	729,672	SH		DFND		0	0	729,672
ALTUS MIDSTREAM CO CL A	COM	02215L100	7,823	2,103,019	SH		DFND		0	0	2,103,019
AMAZON.COM INC	COM	023135106	418,959	221,247	SH		DFND		0	0	221,247
AMERICAN EAGLE OUTFITTERS INC COM	COM	02553E106	53,602	3,171,727	SH		DFND		0	0	3,171,727
AMERICAN TOWER CORP COM USD0.01	COM	03027X100	16,875	82,537	SH		DFND		0	0	82,537
AMICUS THERAPEUTICS INC	COM	03152W109	187	15,000	SH		DFND		0	0	15,000
AMYRIS INC COM NEW	COM	03236M200	194	54,586	SH		DFND		0	0	54,586
ANAPLAN INC COM	COM	03272L108	11,718	232,182	SH		DFND		0	0	232,182
APACHE CORP COM USD0.625	COM	037411105	5,972	206,159	SH		DFND		0	0	206,159
APPFOLIO INC COM CL A	COM	03783C100	23,600	230,766	SH		DFND		0	0	230,766
APPIAN CORP CL A	COM	03782L101	2,357	65,352	SH		DFND		0	0	65,352
APPLIED OPTOELECTRONICS INC COM	COM	03823U102	78	7,560	SH		DFND		0	0	7,560
AQUANTIA CORP COM	COM	03842Q108	7,955	610,546	SH		DFND		0	0	610,546
ARCO PLATFORM LTD COM USD0.00005 CL A	COM	G04553106	17,618	402,427	SH		DFND		0	0	402,427
ARCUS BIOSCIENCES INC COM	COM	03969F109	163	20,443	SH		DFND		0	0	20,443
ARENA PHARMACEUTICALS INC COM NEW	COM	040047607	643	10,971	SH		DFND		0	0	10,971
ARISTA NETWORKS INC COM USD0.0001	COM	040413106	110,067	423,955	SH		DFND		0	0	423,955
ASV HLDGS INC COM	COM	00215L104	4,754	694,070	SH		DFND		0	0	694,070
ATLASSIAN CORPORATION PLC COM USD0.1 CL A	COM	G06242104	24,988	190,978	SH		DFND		0	0	190,978
AUDENTES THERAPEUTICS INC COM	COM	05070R104	66,632	1,759,958	SH		DFND		0	0	1,759,958
AUTO TRADER GROUP PLC ORD GBP0.01 ISIN #GB00BVYVFW23 SEDOL #BVYV	COM	G06708104	5,955	854,080	SH		DFND		0	0	854,080
AUTODESK INC COM	COM	052769106	143,073	878,286	SH		DFND		0	0	878,286
AVEDRO INC COM	COM	05355N109	335	17,035	SH		DFND		0	0	17,035
AXIS BANK GDR EACH REPR 1 INR10 REG S ISIN #US05462W1099 SEDOL #	COM	05462W109	878	15,085	SH		DFND		0	0	15,085
AXOGEN INC COM	COM	05463X106	11,174	564,342	SH		DFND		0	0	564,342
AZUL SA SPON ADR EACH REP 3 PFD SHS	COM	05501U106	117,629	3,517,620	SH		DFND		0	0	3,517,620
AZURRX BIOPHARMA INC COM	COM	05502L105	926	544,606	SH		DFND		0	0	544,606
BANDWIDTH INC COM CL A	COM	05988J103	40,460	539,328	SH		DFND		0	0	539,328
BARCLAYS BANK PLC IPATH B SHRT TERM	COM	06746P621	5,926	227,938	SH		DFND		0	0	227,938
BERKLEY W R CORP COM	COM	084423102	5,880	89,189	SH		DFND		0	0	89,189
BERKSHIRE HATHAWAY INC COM USD0.0033 CLASS B	COM	084670702	288	1,351	SH		DFND		0	0	1,351
BEYOND MEAT INC COM	COM	08862E109	7,929	49,345	SH		DFND		0	0	49,345
BIOSCRIP INC	COM	09069N108	40,910	15,734,496	SH		DFND		0	0	15,734,496
BLACK KNIGHT INC COM	COM	09215C105	5,448	90,576	SH		DFND		0	0	90,576
BLUEBIRD BIO INC COM	COM	09609G100	5,024	39,500	SH		DFND		0	0	39,500
BOSTON SCIENTIFIC CORP	COM	101137107	1,810	42,120	SH		DFND		0	0	42,120
BRIGHTCOVE INC COM USD0.001	COM	10921T101	308	29,834	SH		DFND		0	0	29,834
CALIX INC COM	COM	13100M509	854	130,177	SH		DFND		0	0	130,177
CALYXT INC COM	COM	13173L107	122	9,783	SH		DFND		0	0	9,783
CAREDX INC COM	COM	14167L103	2,991	83,112	SH		DFND		0	0	83,112
CARL ZEISS MEDITEC AG NPV ISIN #DE0005313704 SEDOL #5922961	COM	D14895102	1,739	17,569	SH		DFND		0	0	17,569
CARVANA CO CL A	COM	146869102	18,044	288,296	SH		DFND		0	0	288,296
CATAPULT GROUP INTERNATIONAL ISIN #AU000000CAT9 SEDOL #BTL0Y76	COM	Q2159P101	160	208,773	SH		DFND		0	0	208,773
CHARLOTTES WEB HOLDINGS INC COM NPV	COM	16106R109	1,088	74,331	SH		DFND		0	0	74,331
CHART INDUSTRIES INC COM USD0.01	COM	16115Q308	9,403	122,302	SH		DFND		0	0	122,302
CHEGG INC COM USD0.001	COM	163092109	178,153	4,616,555	SH		DFND		0	0	4,616,555
CHEWY INC CL A	COM	16679L109	419	11,963	SH		DFND		0	0	11,963
CHIPOTLE MEXICAN GRILL INC COM	COM	169656105	23	32	SH		DFND		0	0	32
CODEXIS INC COM USD0.0001	COM	192005106	46,221	2,507,900	SH		DFND		0	0	2,507,900
CONSTRUCTION PARTNERS INC COM CL A	COM	21044C107	110	7,306	SH		DFND		0	0	7,306
COUPA SOFTWARE INC COM	COM	22266L106	34,145	269,690	SH		DFND		0	0	269,690
COVANTA HLDG CORP COM	COM	22282E102	8,483	473,660	SH		DFND		0	0	473,660
CRIMSON WINE GROUP COM USD0.01	COM	22662X100	662	82,773	SH		DFND		0	0	82,773
CROWDSTRIKE HLDGS INC CL A WHEN DISTRIBUTED	COM	22788C105	6,761	99,006	SH		DFND		0	0	99,006
DEERE & COMPANY	COM	244199105	17	100	SH		DFND		0	0	100
DEXCOM INC	COM	252131107	113,320	756,275	SH		DFND		0	0	756,275
DIGI INTL INC COM	COM	253798102	820	64,640	SH		DFND		0	0	64,640
DISNEY WALT CO	COM	254687106	13,753	98,490	SH		DFND		0	0	98,490
DOCUSIGN INC COM	COM	256163106	1,496	30,088	SH		DFND		0	0	30,088
EHEALTH INC COM	COM	28238P109	47,329	549,700	SH		DFND		0	0	549,700
ELASTIC N V COM EUR0.01	COM	N14506104	8,786	117,676	SH		DFND		0	0	117,676
ELECTRONIC ARTS	COM	285512109	196	1,931	SH		DFND		0	0	1,931
ENPHASE ENERGY INC COM USD0.00001	COM	29355A107	71,568	3,925,840	SH		DFND		0	0	3,925,840
ENTERCOM COMMUNICATIONS CORP CL A	COM	293639100	5,884	1,014,407	SH		DFND		0	0	1,014,407
EPAM SYS INC COM USD0.001	COM	29414B104	98,016	566,242	SH		DFND		0	0	566,242
EROS INTERNATIONAL COM GBP0.30	COM	G3788M114	1,154	855,016	SH		DFND		0	0	855,016
ESPERION THERAPEUTICS INC COM USD0.001	COM	29664W105	53	1,132	SH		DFND		0	0	1,132
ETSY INC COM	COM	29786A106	219,625	3,578,703	SH		DFND		0	0	3,578,703
EVERBRIDGE INC COM	COM	29978A104	16,470	184,184	SH		DFND		0	0	184,184
EXACT SCIENCES CORP	COM	30063P105	222,893	1,888,287	SH		DFND		0	0	1,888,287
EXTRACTION OIL AND GAS INC COM	COM	30227M105	504	116,355	SH		DFND		0	0	116,355
FACEBOOK INC-CLASS A	COM	30303M102	73,212	379,339	SH		DFND		0	0	379,339
FARFETCH LTD COM USD0.04 CLASS A	COM	30744W107	28,608	1,375,363	SH		DFND		0	0	1,375,363
FASTLY INC CL A	COM	31188V100	6,068	299,197	SH		DFND		0	0	299,197
FIVE BELOW INC COM	COM	33829M101	83,173	692,996	SH		DFND		0	0	692,996
FLEX LNG LTD (BM) USD0.10 ISIN #BMG359472021 SEDOL #BJJMGB2	COM	ZZCKKNHC2	5,647	478,588	SH		DFND		0	0	478,588
FLEXION THERAPEUTICS INC COM	COM	33938J106	10,340	840,650	SH		DFND		0	0	840,650
FLIR SYS INC	COM	302445101	18,014	332,983	SH		DFND		0	0	332,983
FLOOR &DECOR HLDGS INC CL A	COM	339750101	17,062	407,204	SH		DFND		0	0	407,204
FORESCOUT TECHNOLOGIES INC COM	COM	34553D101	14,415	425,733	SH		DFND		0	0	425,733
FORTESCUE METALS GROUP LTD NPV ISIN #AU000000FMG4 SEDOL #6086253	COM	Q39360104	4,916	776,659	SH		DFND		0	0	776,659
FRANCO NEVADA CORP COM ISIN #CA3518581051 SEDOL #B29NF31	COM	351858105	6,538	77,030	SH		DFND		0	0	77,030
FRESHPET INC COM	COM	358039105	115,940	2,547,572	SH		DFND		0	0	2,547,572
FUNKO INC COM CL A	COM	361008105	3,184	131,460	SH		DFND		0	0	131,460
GALAPAGOS NV NPV ISIN #BE0003818359 SEDOL #B07Q2V5	COM	B44170106	97,789	756,902	SH		DFND		0	0	756,902
GASLOG LTD COM USD0.01	COM	G37585109	2,571	178,563	SH		DFND		0	0	178,563
GEOPARK LIMITED COM USD0.001	COM	G38327105	4,101	221,194	SH		DFND		0	0	221,194
GLAUKOS CORP COM	COM	377322102	108,724	1,441,959	SH		DFND		0	0	1,441,959
GLOBANT SA USD1.20	COM	L44385109	77,960	771,497	SH		DFND		0	0	771,497
GOGO INC COM	COM	38046C109	280	70,448	SH		DFND		0	0	70,448
GOL LINHAS AEREAS INTELIGENTES SA PFD	COM	38045R206	6,993	414,267	SH		DFND		0	0	414,267
GOLAR LNG LIMITED COM STK USD1.00	COM	G9456A100	3,241	175,394	SH		DFND		0	0	175,394
GOLDMAN SACHS GROUP INC COM USD0.01	COM	38141G104	88,764	433,841	SH		DFND		0	0	433,841
GOOSEHEAD INS INC COM CL A	COM	38267D109	26,502	554,428	SH		DFND		0	0	554,428
GRACE(W.R.)&CO COM USD0.01	COM	38388F108	15,303	201,068	SH		DFND		0	0	201,068
GROCERY OUTLET HLDG CORP COM	COM	39874R101	658	20,000	SH		DFND		0	0	20,000
GRUPO FINANCIERO GALICIA SA SPON ADR EACH REP 10 CL B SHS	COM	399909100	2,147	60,479	SH		DFND		0	0	60,479
GTT COMMUNICATIONS INC COM USD0.0001	COM	362393100	25,583	1,453,563	SH		DFND		0	0	1,453,563
GUARDANT HEALTH INC COM	COM	40131M109	59	685	SH		DFND		0	0	685
GUIDEWIRE SOFTWARE INC COM USD0.0001	COM	40171V100	509	5,021	SH		DFND		0	0	5,021
GW PHARMACEUTICALS PLC ADS	COM	36197T103	494	2,864	SH		DFND		0	0	2,864
HDFC BANK LTD SPON ADS EACH REP 3 ORD SHS	COM	40415F101	54,844	421,745	SH		DFND		0	0	421,745
HEALTH INS INNOVATIONS INC COM CL A	COM	42225K106	361	13,940	SH		DFND		0	0	13,940
HEALTHEQUITY INC COM	COM	42226A107	4,449	68,034	SH		DFND		0	0	68,034
HEICO CORP	COM	422806109	177	1,322	SH		DFND		0	0	1,322
HEICO CORP COM USD0.01	COM	422806208	6,957	67,298	SH		DFND		0	0	67,298
HOWARD HUGHES CORP COM	COM	44267D107	276	2,229	SH		DFND		0	0	2,229
HUBSPOT INC COM	COM	443573100	131,983	774,003	SH		DFND		0	0	774,003
ICICI BANK LIMITED SPON ADR EACH REPR 2 ORD SHS	COM	45104G104	5,954	472,935	SH		DFND		0	0	472,935
ILLUMINA INC COM USD0.01	COM	452327109	38,661	105,014	SH		DFND		0	0	105,014
IMPINJ INC COM	COM	453204109	1,346	47,036	SH		DFND		0	0	47,036
INSPIRE MED SYS INC COM	COM	457730109	16,906	278,755	SH		DFND		0	0	278,755
INSULET CORP COM	COM	45784P101	2,729	22,857	SH		DFND		0	0	22,857
INTUITIVE SURGICAL INC COM NEW	COM	46120E602	105,315	200,772	SH		DFND		0	0	200,772
INVITAE CORP COM	COM	46185L103	122,516	5,213,466	SH		DFND		0	0	5,213,466
IOVANCE BIOTHERAPEUTICS INC COM	COM	462260100	3,410	139,080	SH		DFND		0	0	139,080
IQIYI INC SPON EACH ADS REP 7 ORD SHS CLASS A	COM	46267X108	7,827	379,054	SH		DFND		0	0	379,054
IRHYTHM TECHNOLOGIES INC COM	COM	450056106	8,795	111,222	SH		DFND		0	0	111,222
IROBOT CORP COM	COM	462726100	77,166	842,056	SH		DFND		0	0	842,056
JPMORGAN CHASE &CO. COM USD1.00	COM	46625H100	8,351	74,692	SH		DFND		0	0	74,692
KB HOME COM	COM	48666K109	203	7,908	SH		DFND		0	0	7,908
KIRKLAND LAKE GOLD COM NPV ISIN #CA49741E1007 SEDOL #BD4G349	COM	49741E100	17,352	404,297	SH		DFND		0	0	404,297
KORNIT DIGITAL LTD ORD ILS0.01	COM	M6372Q113	33,541	1,059,419	SH		DFND		0	0	1,059,419
LENDINGTREE INC NEW COM	COM	52603B107	400	953	SH		DFND		0	0	953
LGI HOMES INC COM	COM	50187T106	100,320	1,404,450	SH		DFND		0	0	1,404,450
LHC GROUP INC COM	COM	50187A107	7,036	58,841	SH		DFND		0	0	58,841
LIBERTY MEDIA CORP DELAWARE COM A BRAVES GRP	COM	531229706	4,491	161,556	SH		DFND		0	0	161,556
LIBERTY MEDIA CORP DELAWARE COM C BRAVES GRP	COM	531229888	16,992	607,493	SH		DFND		0	0	607,493
LIBERTY MEDIA CORP DELAWARE COM SER C FRMLA	COM	531229854	4,569	122,121	SH		DFND		0	0	122,121
LIVEPERSON INC COM USD0.001	COM	538146101	85,332	3,043,221	SH		DFND		0	0	3,043,221
LONZA GROUP AG-REG ISIN #CH0013841017 SEDOL #7333378	COM	H50524133	37,206	110,128	SH		DFND		0	0	110,128
LOVESAC COMPANY COM	COM	54738L109	9,064	291,731	SH		DFND		0	0	291,731
LULULEMON ATHLETICA INC COM USD0.005	COM	550021109	6,895	38,263	SH		DFND		0	0	38,263
LUMENTUM HLDGS INC COM	COM	55024U109	1,043	19,525	SH		DFND		0	0	19,525
LYFT INC CL A COM	COM	55087P104	57,690	877,954	SH		DFND		0	0	877,954
MADISON SQUARE GARDEN CO NEW CL A	COM	55825T103	6,930	24,757	SH		DFND		0	0	24,757
MAG SILVER CORP COM NPV ISIN #CA55903Q1046 SEDOL #2581332	COM	55903Q104	16,720	1,586,357	SH		DFND		0	0	1,586,357
MAGENTA THERAPEUTICS INC COM	COM	55910K108	61,552	4,172,988	SH		DFND		0	0	4,172,988
MAGNOLIA OIL &GAS CORP CL A	COM	559663109	7,247	625,835	SH		DFND		0	0	625,835
MAKEMYTRIP LTD USD0.0005	COM	V5633W109	2,448	98,698	SH		DFND		0	0	98,698
MARTIN MARIETTA MATERIALS INC COM USD0.01	COM	573284106	108,984	473,617	SH		DFND		0	0	473,617
MASTERCARD INC CL A	COM	57636Q104	24,864	93,994	SH		DFND		0	0	93,994
MATCH GROUP INC COM	COM	57665R106	72,893	1,083,594	SH		DFND		0	0	1,083,594
MAYVILLE ENGINEERING CO INC COM	COM	578605107	7,774	563,332	SH		DFND		0	0	563,332
MERCADOLIBRE INC COM USD0.001	COM	58733R102	97,610	159,553	SH		DFND		0	0	159,553
MERCURY SYS INC COM	COM	589378108	247	3,518	SH		DFND		0	0	3,518
MESA AIR GROUP INC COM NEW	COM	590479135	6,897	754,620	SH		DFND		0	0	754,620
MICROSOFT CORP	COM	594918104	77,386	577,676	SH		DFND		0	0	577,676
MIMECAST LIMITED COM USD0.012	COM	G14838109	1,329	28,461	SH		DFND		0	0	28,461
MISONIX INC	COM	604871103	4,788	188,352	SH		DFND		0	0	188,352
MOLECULAR TEMPLATES INC COM	COM	608550109	8,174	978,916	SH		DFND		0	0	978,916
MONGODB INC CL A	COM	60937P106	193,571	1,272,738	SH		DFND		0	0	1,272,738
MONOLITHIC PWR SYS INC COM	COM	609839105	13,558	99,854	SH		DFND		0	0	99,854
NEOPHOTONICS CORP COM	COM	64051T100	568	135,814	SH		DFND		0	0	135,814
NETFLIX COM INC COM	COM	64110L106	522,246	1,421,773	SH		DFND		0	0	1,421,773
NEW PACIFIC METALS CORP COM NPV ISIN #CA6478241012 SEDOL #BF4CP8	COM	647824101	2,295	1,249,546	SH		DFND		0	0	1,249,546
NEW RELIC INC COM	COM	64829B100	8,972	103,708	SH		DFND		0	0	103,708
NEW YORK TIMES CO CL A	COM	650111107	169,091	5,183,649	SH		DFND		0	0	5,183,649
NINTENDO CO LTD ADR(8 CNV INTO 1 ORD)NPV	COM	654445303	2,855	62,309	SH		DFND		0	0	62,309
NOBLE MIDSTREAM PARTNERS LP COM UNIT REPST	COM	65506L105	34	1,014	SH		DFND		0	0	1,014
NUVECTRA CORP COM	COM	67075N108	2,668	796,325	SH		DFND		0	0	796,325
NV5 GLOBAL INC COM	COM	62945V109	7,753	95,240	SH		DFND		0	0	95,240
NVIDIA CORP	COM	67066G104	30,047	182,959	SH		DFND		0	0	182,959
OCADO GROUP PLC ORD GBP0.02 ISIN #GB00B3MBS747 SEDOL #B3MBS74	COM	G6718L106	189,221	12,740,079	SH		DFND		0	0	12,740,079
OKTA INC CL A	COM	679295105	257,531	2,085,099	SH		DFND		0	0	2,085,099
PAGERDUTY INC COM	COM	69553P100	6,983	148,427	SH		DFND		0	0	148,427
PALO ALTO NETWORKS INC COM USD0.0001	COM	697435105	17,492	85,845	SH		DFND		0	0	85,845
PALOMAR HLDGS INC COM	COM	69753M105	2,389	99,366	SH		DFND		0	0	99,366
PARAMOUNT RESOURCES LIMITED COM NPV CLASS A ISIN #CA6993202069 S	COM	699320206	824	164,918	SH		DFND		0	0	164,918
PAYPAL HLDGS INC COM	COM	70450Y103	24,910	217,631	SH		DFND		0	0	217,631
PDF SOLUTIONS INC	COM	693282105	728	55,477	SH		DFND		0	0	55,477
PDVWIRELESS INC COM	COM	69290R104	360	7,663	SH		DFND		0	0	7,663
PENSKE AUTOMOTIVE GROUP INC	COM	70959W103	3,373	71,313	SH		DFND		0	0	71,313
PENUMBRA INC COM	COM	70975L107	780	4,876	SH		DFND		0	0	4,876
PINDUODUO INC SPON ADS EACH REP 4 ORD SHS	COM	722304102	219	10,600	SH		DFND		0	0	10,600
PINTEREST INC CL A	COM	72352L106	35,616	1,308,459	SH		DFND		0	0	1,308,459
PIVOTAL SOFTWARE INC COM CL A	COM	72582H107	3,118	295,247	SH		DFND		0	0	295,247
PLANET FITNESS INC CL A	COM	72703H101	3,272	45,168	SH		DFND		0	0	45,168
PLURALSIGHT INC COM CL A	COM	72941B106	4,479	147,737	SH		DFND		0	0	147,737
POOL CORP COM	COM	73278L105	74,114	388,030	SH		DFND		0	0	388,030
PREVAIL THERAPEUTICS INC COM	COM	74140Y101	389	29,480	SH		DFND		0	0	29,480
PROOFPOINT INC COM USD0.0001	COM	743424103	5,918	49,217	SH		DFND		0	0	49,217
Q2 HLDGS INC COM	COM	74736L109	84,945	1,112,431	SH		DFND		0	0	1,112,431
QUANTERIX CORP COM	COM	74766Q101	103,673	3,068,168	SH		DFND		0	0	3,068,168
QUOTIENT LTD COM NPV	COM	G73268107	4,183	447,361	SH		DFND		0	0	447,361
R1 RCM INC COM	COM	749397105	6,865	545,696	SH		DFND		0	0	545,696
REECE LIMITED NPV ISIN #AU000000REH4 SEDOL #6728801	COM	Q80528138	5,239	764,850	SH		DFND		0	0	764,850
RELIANCE INDUSTRIES SPON GDR EACH REP 2 ORD SHS 144A ISIN #US759	COM	ZZC27DZQ8	263	7,287	SH		DFND		0	0	7,287
REVOLVE GROUP INC CL A	COM	76156B107	698	20,229	SH		DFND		0	0	20,229
RIGHTMOVE ORD GBP0.001 ISIN #GB00BGDT3G23 SEDOL #BGDT3G2	COM	G7565D106	15,990	2,349,655	SH		DFND		0	0	2,349,655
RINGCENTRAL INC-CLASS A	COM	76680R206	207,866	1,808,792	SH		DFND		0	0	1,808,792
ROKU INC COM CL A	COM	77543R102	319,298	3,525,035	SH		DFND		0	0	3,525,035
ROYAL GOLD INC COM ISIN #US7802871084 SEDOL #2430553	COM	780287108	20	198	SH		DFND		0	0	198
SAFETY INS GROUP INC	COM	78648T100	449	4,720	SH		DFND		0	0	4,720
SALESFORCE.COM INC COM USD0.001	COM	79466L302	94,365	621,928	SH		DFND		0	0	621,928
SAREPTA THERAPEUTICS INC COM	COM	803607100	150,735	992,007	SH		DFND		0	0	992,007
SCORPIO TANKERS INC COM USD0.01 (POST REV SPLIT)	COM	Y7542C130	383	12,961	SH		DFND		0	0	12,961
SEASPINE HLDGS CORP COM	COM	81255T108	317	23,940	SH		DFND		0	0	23,940
SEMLER SCIENTIFIC INC COM USD0.001	COM	81684M104	4,150	94,970	SH		DFND		0	0	94,970
SENESTECH INC COM	COM	81720R109	2,215	1,230,790	SH		DFND		0	0	1,230,790
SENSEONICS HLDGS INC COM	COM	81727U105	34,699	17,009,227	SH		DFND		0	0	17,009,227
SERVICENOW INC COM USD0.001	COM	81762P102	38,553	140,414	SH		DFND		0	0	140,414
SHAKE SHACK INC CL A	COM	819047101	168,990	2,340,584	SH		DFND		0	0	2,340,584
SHERWIN WILLIAMS CO	COM	824348106	959	2,092	SH		DFND		0	0	2,092
SHOCKWAVE MED INC COM	COM	82489T104	82,632	1,447,401	SH		DFND		0	0	1,447,401
SHOPIFY INC COM NPV CL A ISIN #CA82509L1076 SEDOL #BX865C7	COM	82509L107	113,063	376,687	SH		DFND		0	0	376,687
SHOTSPOTTER INC COM	COM	82536T107	97,153	2,198,021	SH		DFND		0	0	2,198,021
SI BONE INC COM	COM	825704109	8,718	428,633	SH		DFND		0	0	428,633
SILK ROAD MEDICAL INC COM	COM	82710M100	2,923	60,320	SH		DFND		0	0	60,320
SILVERCREST METALS INC COM NPV ISIN #CA8283631015 SEDOL #BYVY3D2	COM	828363101	20,558	5,063,551	SH		DFND		0	0	5,063,551
SITEONE LANDSCAPE SUPPLY INC COM	COM	82982L103	21,453	309,561	SH		DFND		0	0	309,561
SIX FLAGS ENTMT CORP NEW COM	COM	83001A102	3,811	76,721	SH		DFND		0	0	76,721
SLACK TECHNOLOGIES INC COM CL A	COM	83088V102	97,048	2,587,944	SH		DFND		0	0	2,587,944
SNAP INC CL A	COM	83304A106	9,414	658,321	SH		DFND		0	0	658,321
SOCIAL CAP HEDOSOPHIA HLDGS CORP UNIT 1 CL A & 1/3 WT EXP ISIN #	COM	G8250R111	1,839	172,210	SH		DFND		0	0	172,210
SOLARIS OILFIELD INFRSTR INC COM CL A	COM	83418M103	8,136	543,126	SH		DFND		0	0	543,126
SPLUNK INC COM USD0.001	COM	848637104	6,121	48,673	SH		DFND		0	0	48,673
SPOTIFY TECHNOLOGY S.A. COM EUR0.000625	COM	L8681T102	390	2,669	SH		DFND		0	0	2,669
SQUARE INC CL A	COM	852234103	122,371	1,687,184	SH		DFND		0	0	1,687,184
SS&C TECHNOLOGIES HLDGS INC COM	COM	78467J100	59,519	1,033,139	SH		DFND		0	0	1,033,139
STAAR SURGICAL CO COM NEW PAR $0.01	COM	852312305	2,865	97,513	SH		DFND		0	0	97,513
STAR BULK CARRIERS CORP COM USD0.01(POST REV SPLIT)	COM	Y8162K204	606	62,773	SH		DFND		0	0	62,773
STARS GROUP INC(THE) COM NPV ISIN #CA85570W1005 SEDOL #BDG1MJ0	COM	85570W100	356	20,854	SH		DFND		0	0	20,854
STITCH FIX INC COM CL A	COM	860897107	17,065	533,457	SH		DFND		0	0	533,457
STOKE THERAPEUTICS INC COM	COM	86150R107	54,304	1,861,623	SH		DFND		0	0	1,861,623
STONECO LTD COM USD0.000079365 CLASS A	COM	G85158106	43,949	1,485,764	SH		DFND		0	0	1,485,764
SUNRUN INC COM	COM	86771W105	1,535	81,813	SH		DFND		0	0	81,813
SVB FINL GROUP	COM	78486Q101	13,424	59,770	SH		DFND		0	0	59,770
T MOBILE US INC COM USD0.00001	COM	872590104	95,516	1,288,324	SH		DFND		0	0	1,288,324
TACTILE SYS TECHNOLOGY INC COM	COM	87357P100	4,504	79,131	SH		DFND		0	0	79,131
TAKEAWAY.COM N.V. EUR0.04 144A ISIN #NL0012015705 SEDOL #BYQ7HZ6	COM	N84437107	206	2,194	SH		DFND		0	0	2,194
TAL EDUCATION GROUP SPON ADS EACH REP 0.3333 CL A ORD SHS	COM	874080104	46,348	1,216,486	SH		DFND		0	0	1,216,486
TANDEM DIABETES CARE INC COM NEW	COM	875372203	40,975	635,079	SH		DFND		0	0	635,079
TELADOC HEALTH INC COM	COM	87918A105	88,767	1,336,647	SH		DFND		0	0	1,336,647
TENCENT HOLDINGS LIMITED HKD0.00002 ISIN #KYG875721634 SEDOL #BM	COM	G87572163	63,492	1,406,778	SH		DFND		0	0	1,406,778
TESLA INC COM	COM	88160R101	108,342	484,837	SH		DFND		0	0	484,837
THE A2 MILK COMPANY LTD NPV ISIN #NZATME0002S8 SEDOL #BWSRTS7	COM	ZZCXTSUT2	18,365	1,889,515	SH		DFND		0	0	1,889,515
THE REALREAL INC COM	COM	88339P101	1,445	50,000	SH		DFND		0	0	50,000
THOR INDS INC	COM	885160101	2,743	46,929	SH		DFND		0	0	46,929
TRANSDIGM GROUP INC COM	COM	893641100	7,750	16,020	SH		DFND		0	0	16,020
TRUPANION INC COM USD0.00001	COM	898202106	6,262	173,327	SH		DFND		0	0	173,327
TWILIO INC CL A	COM	90138F102	14,472	106,140	SH		DFND		0	0	106,140
TWIST BIOSCIENCE CORP COM	COM	90184D100	8,098	279,141	SH		DFND		0	0	279,141
TWITTER INC COM USD0.000005	COM	90184L102	104,859	3,004,564	SH		DFND		0	0	3,004,564
UBER TECHNOLOGIES INC COM	COM	90353T100	117,077	2,524,305	SH		DFND		0	0	2,524,305
UBIQUITI NETWORKS INC COM USD0.001	COM	90347A100	200	1,522	SH		DFND		0	0	1,522
UNDER ARMOUR INC COM STK USD0.000333 CLASS A	COM	904311107	261	10,308	SH		DFND		0	0	10,308
VANECK VECTORS ETF TR GOLD MINERS ETF	COM	92189F106	11,201	438,223	SH		DFND		0	0	438,223
VAPOTHERM INC COM	COM	922107107	3,310	143,903	SH		DFND		0	0	143,903
VEEVA SYS INC CL A COM	COM	922475108	22,470	138,611	SH		DFND		0	0	138,611
VERACYTE INC COM	COM	92337F107	110,375	3,871,451	SH		DFND		0	0	3,871,451
VERIZON COMMUNICATIONS	COM	92343V104	12,240	214,244	SH		DFND		0	0	214,244
VIEWRAY INC COM	COM	92672L107	3,718	422,061	SH		DFND		0	0	422,061
VULCAN MATERIALS CO	COM	929160109	5,117	37,264	SH		DFND		0	0	37,264
WHEATON PRECIOUS METALS CORP COM NPV ISIN #CA9628791027 SEDOL #B	COM	962879102	1,946	80,478	SH		DFND		0	0	80,478
WILLSCOT CORP COM	COM	971375126	875	58,174	SH		DFND		0	0	58,174
WORKDAY INC COM USD0.001 CL A	COM	98138H101	43,066	209,484	SH		DFND		0	0	209,484
WORLD WRESTLING ENTERTAINMENT INC CL A	COM	98156Q108	72,448	1,003,298	SH		DFND		0	0	1,003,298
WUXI BIOLOGICS (CAYMAN) INC USD0.000025 144A REG S ISIN #KYG9700	COM	G97008109	13,742	1,530,449	SH		DFND		0	0	1,530,449
YETI HLDGS INC COM	COM	98585X104	2,064	71,302	SH		DFND		0	0	71,302
ZAI LAB LIMITED ADS EACH REP 1 ORD SHS	COM	98887Q104	40,585	1,163,886	SH		DFND		0	0	1,163,886
ZENDESK INC COM USD0.01	COM	98936J101	12,462	139,975	SH		DFND		0	0	139,975
ZILLOW GROUP INC CL A	COM	98954M101	387	8,455	SH		DFND		0	0	8,455
ZOOM VIDEO COMMUNICATIONS INC CL A	COM	98980L101	5,651	63,650	SH		DFND		0	0	63,650
ZUORA INC COM CL A	COM	98983V106	3,134	204,565	SH		DFND		0	0	204,565