June 6, 2006
VIA ELECTRONIC SUBMISSION
Securities and Exchange Commission
Division of Corporation Finance
450 Fifth Street, N.W., Mail Stop 3-9
Judiciary Plaza
Washington, DC 20549
Attention: Jim B. Rosenberg
Senior Assistant Chief Accountant
| Re: | Trimeris, Inc. |
Form 10-K for the fiscal year ended December 31, 2005
Filed March 10, 2006
Form 10-Q for the quarter ended March 31, 2006
Filed May 10, 2006
File No. 000-23155
Dear Mr. Rosenberg
Further to our discussion with Keira Ino on May 30, 2006, we hereby request an extension of the deadline for our response to your letter dated May 24, 2006. We will provide our response as soon as practicable but no later than June 15, 2006.
Please feel free to contact us if you need any further information. Thank you.
| Sincerely, |
/s/ Robert R. Bonczek |
| Robert R. Bonczek |
| Chief Financial Officer |