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| Hampshire International Business Park Chineham Basingstoke Hampshire RG24 8EP United Kingdom Tel +44 (0)1256 894000 Fax +44 (0)1256 894708 www.shire.com |  |
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| Press Release | |
7 November 2005
Shire Pharmaceuticals Group plc (the "Company")
The Company announces that it was notified today, in accordance with Sections 198 to 202 of the Companies Act, that as at 2 November 2005, Barclays PLC, through its associated companies, held a notifiable interest, in aggregate, of 20,290,124 ordinary shares of £0.05p each in the capital of the Company. These holdings represent 4.10 per cent of the issued ordinary share capital of the Company.
T May
Company Secretary
For further information please contact:
Investor Relations | | Cléa Rosenfeld (Rest of the World) | + | 44 1256 894 160 |
| | Brian Piper (North America) | + | 1 484 595 8252 |
Notes to editors
Shire Pharmaceuticals Group plc
Shire Pharmaceuticals Group plc (Shire) is a global specialty pharmaceutical company with a strategic focus on meeting the needs of the specialist physician and currently focuses on developing and marketing products in the areas of central nervous system (CNS), gastrointestinal (GI), general products and human genetic therapies. Shire has operations in the world’s key pharmaceutical markets (US, Canada, UK, France, Italy, Spain and Germany) as well as a specialist drug delivery unit in the US.
For further information on Shire, please visit the Company’s website:www.shire.com.
Registered in England 2883758 Registered Office as above