| | | EXHIBIT 99.03 |
| | | |
| | Hampshire International Business Park
Chineham Basingstoke
Hampshire RG24 8EP
United Kingdom
Tel +44 (0)1256 894000
Fax +44 (0)1256 894708
www.shire.com |  |
| | | |
| | Press Release | |
| | | |
Notification of major interests in shares
28 February 2007
1. Identity of the issuer or the underlying issuer of existing shares to which voting rights are attached:
Shire plc
| 2. Reason for the notification | State
Yes/No |
| An acquisition or disposal of voting rights | |
An acquisition or disposal of financial instruments which may result in the
acquisition of shares already issued to which voting rights are attached | |
| An event changing the breakdown of voting rights | Yes |
| Other (please specify): | |
| 3. Full name of person(s) subject to the notification obligation: | Fidelity
International
Limited (FIL) |
| 4. Full name of shareholder(s) (if different from 3.): | See attached |
| | schedule |
5. Date of the transaction (and date on which the threshold is crossed
or reached if different): | Revised due to
DTR rules |
| 6. Date on which issuer notified: | 27 February
2007 |
| 7. Threshold(s) that is/are crossed or reached: | |
| 8. Notified details: | |
A: Voting rights attached to shares
Class/type of shares
if possible using the ISIN CODE | Situation previous to
the Triggering
transaction | Resulting situation after the triggering
transaction |
| | Number of
Shares | Numberof
Voting Rights | Number of
shares | Number of voting
rights | % of voting rights |
Registered in England 2883758 Registered Office as above
| | | | Direct | Direct | Indirect | Direct | Indirect |
| GB00B0KQX869 | 26,759,374 | 26,759,374 | | | 26,759,374 | | 5.23% |
B: Financial Instruments
Resulting situation after the triggering transaction
Type of
financial
instrument | Expiration
date | Exercise/Conversion
Period/ Date | Number of voting
rights that may be
acquired if the instrument
is exercised/converted | % of voting
rights |
| | | | | |
| Total (A+B) | |
| Number of voting rights | % of voting rights |
| 26,759,374 | 5.23% |
9. Chain of controlled undertakings through which the voting rights and/or the financial instruments are effectively held, if applicable:
Proxy Voting:
| 10. Name of the proxy holder: | Fidelity International
Limited (FIL) |
| 11. Number of voting rights proxy holder will cease to hold: | N/A |
| 12. Date on which proxy holder will cease to hold voting rights: | N/A |
| 13. Additional information: | As discussed with the FSA, prior to the implementation of the EU Transparency Directive, we aggregated the interests in the shares of FMR Corp (FMR) and Fidelity International Limited (FIL) together for the purposes of shareholder reporting. According to the new DTR rules we are now reporting the indirect holdings of FMR and FIL separately. A separate notification is being submitted for FILFMR Corp. Please note these holdings are correct as of close of business 26 February 2007. |
| 14. Contact name: | Sophie Hughes |
| 15. Contact telephone number: | 01737 836713 |
(Contact at Shire plc: Vivienne Hemming, Deputy Company Secretary, 01256 894276)
Registered in England 2883758 Registered Office as above
Schedule:
| Shares Held | Nominee | Management Company |
| 23,500 | TRUST&CUST SVCS BK LTD, TOKO | FIJ |
| 27,200 | STATE STREET HONG KONG | FIA(K)L |
| 372,030 | STATE STR BK AND TR CO LNDN (S | FPM |
| 46,700 | STATE STR BK AND TR CO LNDN (S | FIL |
| 977,197 | NORTHERN TRUST LONDON | FPM |
| 170,500 | NORTHERN TRUST LONDON | FIL |
| 52,800 | NORTHERN TRUST CO | FIL |
| 18,200 | NORDDEUTSCHE LANDERSBANK | FIL |
| 46,100 | NOMURA TEST AND BANKING | FIJ |
| 119,300 | MIDLAND SECURITIES SERVICES | FPM |
| 472,900 | MELLON BANK | FPM |
| 88,700 | MASTER TRUST BANK OF JAPAN | FIJ |
| 279,800 | JPMORGAN, BOURNEMOUTH | FIL |
| 922,028 | JPMORGAN, BOURNEMOUTH | FPM |
| 10,770,619 | JPMORGAN, BOURNEMOUTH | FISL |
| 3,417,582 | JPMORGAN, BOURNEMOUTH | FIL |
| 987,772 | JPMORGAN, BOURNEMOUTH | FII |
| 12,200 | DEXIA PRIVATBANK | FPM |
| 23,300 | CHASE MANHTTN BK AG FRNKFRT (S | FPM |
| 65,400 | BROWN BROTHERS HARRIMAN AND CO | FIL |
| 5,471,451 | BROWN BROS HARRIMN LTD LUX | FIL |
| 702,230 | BNP PARIBAS, PARIS | FIGEST |
| 110,300 | BNP PARIBAS, PARIS (C) | FIL |
| 266,500 | BERMUDA TRUST FAR EAST HK | FIM HK |
| 686,800 | BANK OF NEW YORK EUROPE LDN | FII |
| 628,265 | BANK OF NEW YORK BRUSSELS | FPM |
Fidelity International Limited (FIL) is the parent holding company for various direct and indirect subsidiaries, including Fidelity Fund Management Limited (FFML), Fidelity Fund Management Limited (FFML), Fidelity Investment Services Ltd (FISL), Fidelity Gestion (FIGEST), Fidelity Investments Advisory (Korea) Limited (FIAKL), Fidelity Investments Management (Hong Kong) Limited (FIMHK), Fidelity Pension Management (FPM), Fidelity Investments Japan (FLJ) and Fidelity Investments International (FII), investment managers for various non-US investment companies and institutional clients.
For further information please contact:
| Investor Relations | Cléa Rosenfeld (Rest of the World) | +44 1256 894 160 |
| | Eric Rojas (North America) | +1 484 595 8252 |
Notes to editors
SHIRE PLC
Shire’s strategic goal is to become the leading specialty pharmaceutical company that focuses on meeting the needs of the specialist physician. Shire focuses its business on attention deficit and hyperactivity disorder (ADHD), human genetic therapies (HGT), gastrointestinal (GI) and renal diseases. The structure is sufficiently flexible to allow Shire to target new therapeutic areas to the extent opportunities arise through acquisitions. Shire believes that a carefully selected portfolio of products with a strategically aligned and relatively small-scale sales force will deliver strong results.
Registered in England 2883758 Registered Office as above
Shire’s focused strategy is to develop and market products for specialty physicians. Shire’s in-licensing, merger and acquisition efforts are focused on products in niche markets with strong intellectual property protection either in the US or Europe.
For further information on Shire, please visit the Company’s website:www.shire.com.
Registered in England 2883758 Registered Office as above
