Exhibit 23.1
CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM
We consent to the incorporation by reference in Registration Statements on Form S-8 (Nos. 333-09168, 333-93543, 333-60952, 333-91552, 333-111579, 333-129961, 333-129960, 333-111108, 333-202302, 333-175839, 333-165137, and 333-211941) and Post-Effective Amendment No. 2 to the Registration Statement on Form S-4 (No. 333-209648) on Form S-3 of our reports dated February 23, 2016 (September 2, 2016 as to Note 2(z) and Note 29), relating to the consolidated financial statements and financial statement schedule of Shire plc and subsidiaries, and the effectiveness of Shire plc and subsidiaries’ internal control over financial reporting, appearing in this Current Report on Form 8-K of Shire plc dated September 2, 2016.
/s/ Deloitte LLP
Deloitte LLP
London, United Kingdom
September 2, 2016