14 patents
Utility
Methods for preparing substituted 5,6-dihydro-6-phenylbenzo[f]isoquinolin-2-amine
22 Mar 22
Craig Bates, Jianmin Mao, David P. Reed
Filed: 3 Oct 19
Utility
Amino-pyrrolopyrimidinone compounds and methods of use thereof
1 Jun 21
Craig Bates, Sudharshan Eathiraj, Hiroaki Inagaki, Jean-Marc Lapierre, Takayuki Momose, Kiyoshi Nakayama, Takashi Odagiri, Masahiro Ota, Yusuke Ota, Yoshihiro Shibata, Manish Tandon, Tomoyuki Tsunemi
Filed: 23 Aug 17
Utility
Tetrahydropyranyl amino-pyrrolopyrimidinone and methods of use thereof
1 Jun 21
Jean-Marc Lapierre, Sudharshan Eathiraj, Nivedita Namdev, Brian Schwartz, Yusuke Ota, Takayuki Momose, Tomoyuki Tsunemi, Hiroaki Inagaki, Kiyoshi Nakayama
Filed: 4 Nov 19
Utility
Tetrahydropyranyl Amino-pyrrolopyrimidinone and Methods of Use Thereof
20 May 21
Jean-Marc Lapierre, Sudharshan Eathiraj, Nivedita Namdev, Brian Schwartz, Yusuke Ota, Takayuki Momose, Tomoyuki Tsunemi, Hiroaki Inagaki, Kiyoshi Nakayama
Filed: 27 Jan 21
Utility
Solid forms of tetrahydropyranyl amino-pyrrolopyrimidinone compounds
13 Apr 21
The present application provides solid forms of (2-chloro-4-phenoxyphenyl)(4-(((3R,6S)-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)amino)-7H-pyrrolo[2,3-d]pyrimidin-5-yl)methanone free base, and methods of preparing and using the same.
Craig Bates, Erika Volckova
Filed: 13 Aug 19
Utility
Tetrahydropyranyl amino-pyrrolopyrimidinone and methods of use thereof
2 Mar 21
Jean-Marc Lapierre, Sudharshan Eathiraj, Nivedita Namdev, Brian Schwartz, Yusuke Ota, Takayuki Momose, Tomoyuki Tsunemi, Hiroaki Inagaki, Kiyoshi Nakayama
Filed: 4 Mar 19
Utility
Methods for preparing substituted 5,6-dihydro-6-phenylbenzo[f]isoquinolin-2-amine
7 Sep 20
Craig Bates, Jianmin Mao, David P. Reed
Filed: 21 Apr 19
Utility
Solid forms of substituted 5,6-dihydro-6-phenylbenzo[F]isoquinolin-2-amine compounds
20 Jul 20
The present application provides solid forms of (R)-6-(2-fluorophenyl)-N-(3-(2-(2-methoxyethylamino)ethyl)phenyl)-5,6-dihydrobenzo[h]quinazolin-2-amine dihydrochloride, and methods of preparing and using same.
Craig Bates, David P. Reed
Filed: 29 Jan 19
Utility
Pharmaceutical Combination for Treatment of Cancer
20 May 20
The present application is drawn to methods of treating a cell proliferative disorder, such as a cancer, comprising administering to a subject in need thereof a therapeutically effective amount of a composition comprising at least one of Compound 1, Compound 2, and Compound 3, or a pharmaceutically acceptable salt, solvate, hydrate, or prodrug thereof, and at least one second therapeutic agent or a pharmaceutically acceptable salt, solvate, hydrate, or prodrug thereof, wherein the cell proliferative disorder is treated.
Brian SCHWARTZ, Yi YU
Filed: 17 Nov 19
Utility
Solid Forms of Tetrahydropyranyl Amino-pyrrolopyrimidinone Compounds
6 May 20
The present application provides solid forms of (2-chloro-4-phenoxyphenyl)(4-(((3R,6S)-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)amino)-7H-pyrrolo[2,3-d]pyrimidin-5-yl)methanone free base, and methods of preparing and using the same.
Craig BATES, Erika VOLCKOVA
Filed: 12 Aug 19
Utility
Methods for Preparing Substituted 5,6-DIHYDRO-6-PHENYLBENZO[F]ISOQUINOLIN-2-AMINE
1 Apr 20
Craig BATES, Jianmin MAO, David P. REED
Filed: 2 Oct 19
Utility
Tetrahydropyranyl Amino-pyrrolopyrimidinone and Methods of Use Thereof
26 Feb 20
Jean-Marc LAPIERRE, Sudharshan EATHIRAJ, Nivedita NAMDEV, Brian SCHWARTZ, Yusuke OTA, Takayuki MOMOSE, Tomoyuki TSUNEMI, Hiroaki INAGAKI, Kiyoshi NAKAYAMA
Filed: 3 Nov 19
Utility
Solid Forms of Substituted 5,6-DIHYDRO-6-PHENYLBENZO[F]ISOQUINOLIN-2-AMINE Compounds
1 Jan 20
The present application provides solid forms of (R)-6-(2-fluorophenyl)-N-(3-(2-(2-methoxyethylamino)ethyl)phenyl)-5,6-dihydrobenzo[h]quinazolin-2-amine dihydrochloride, and methods of preparing and using same.
Craig BATES, David P. REED
Filed: 29 Jan 19
Utility
Amino-pyrrolopyrimidinone Compounds and Methods of Use Thereof
27 Nov 19
Craig BATES, Sudharshan Eathiraj, Hiroaki Inagaki, Jean-Marc Lapierre, Takayuki Momose, Kiyoshi Nakayama, Takashi Odagiri, Masahiro Ota, Yusuke Ota, Yoshihiro Shibata, Manish Tandon, Tomoyuki Tsunemi
Filed: 4 Aug 19
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