35 patents
Utility
Alkylated Cyclodextrin Compositions and Processes for Preparing and Using the Same
9 Nov 23
The present disclosure is related to processes for efficient large-scale preparation of alkylated cyclodextrins.
Vincent D. ANTLE, Andre FERNANDES, Mariana RODRIGUES, Claudio VILELA
Filed: 23 Sep 21
Utility
Sulfoalkyl ether cyclodextrin compositions
7 Nov 23
SAE-CD compositions are provided, along with methods of making and using the same.
Vincent D. Antle
Filed: 15 Sep 20
Utility
hi0yj5sb2o9bjx9u scj9ax2a093niv4dl
24 Oct 23
The present invention relates to compositions comprising fractionated alkylated cyclodextrin compositions having a single degree of substitution, and processes for preparing and using the same.
Vincent D. Antle, Charles Alan Watson, David W. Miles
Filed: 24 Nov 20
Utility
dllxbcvmobjx2f2cwfb04ss54f1bv
17 Aug 23
Pharmaceutical formulations containing busulfan and cyclodextrin are described.
James D. Pipkin
Filed: 21 Sep 22
Utility
vgc91w44533z8w23bpvnkll6 e7jo
27 Jul 23
Cosmetic and dietary supplement compositions containing silymarin and sulfoalkyl ether cyclodextrin, particularly sulfobutyl ether cyclodextrin, are described.
James D. Pipkin, Roger A. Rajewski, Beau Mainous
Filed: 29 Jun 22
Utility
thkvltejyyzw 6nnj6tezqbcvu411w0inq4jxp03dquw
5 Jan 23
The present disclosure is related to low-chloride alkylated cyclodextrin compositions, along with processes for preparing the same.
Vincent D. Antle
Filed: 16 Nov 20
Utility
u8g548qfqhekykcry0r0ndnqurvklt129d5mzkcbi6eaizptxbi0
8 Dec 22
An aqueous composition of latanoprost and SAE-CD is provided.
Naomi Esaki, James D. Pipkin
Filed: 9 Aug 22
Utility
na3tonb2d 2zzyibscf1geblcgjnqj52no5ldt5ri0dfa350
27 Oct 22
The present invention is directed to methods of treating nasal and/or ophthalmic diseases, symptoms, or disorders that are therapeutically responsive to corticosteroid therapy by delivering aqueous solution formulations comprising a corticosteroid to nasal and ophthalmic tissues.
James D. Pipkin, Rupert O. Zimmerer, John M. Siebert
Filed: 28 Jul 21
Utility
bj5s2v8g4yf5b4p49 0bz
20 Oct 22
A process and equipment assembly for reacting a substituent precursor with a cyclodextrin starting material to provide a raw product comprising a cyclodextrin derivative and 1% or less of an initial amount of the substituent precursor is provided.
Vincent D. Antle, Jose R. Matos
Filed: 17 Dec 21
Utility
fmh2to4mle1scf1abm72h6s1dp6zk93bf34fhzu2h07d7m invjvwgynnb9
11 Oct 22
An inhalable dry powder formulation containing SAE-CD and an active agent is provided.
James D. Pipkin, Gerold L. Mosher, Douglas B. Hecker
Filed: 15 May 20
Utility
f2vanu049flpl2tf84uvu9os0yt8wtk8cyjy15926vzswj2i2o
6 Sep 22
An aqueous composition of latanoprost and SAE-CD is provided.
Naomi Esaki, James D. Pipkin
Filed: 1 Nov 19
Utility
622hx ffbspbg7vb638dtktiry66gc
12 Jul 22
Cosmetic and dietary supplement compositions containing silymarin and sulfoalkyl ether cyclodextrin, particularly sulfobutyl ether cyclodextrin, are described.
James D. Pipkin, Roger A. Rajewski, Beau Mainous
Filed: 2 Jul 20
Utility
6uu4mp 3ufzte5viyd0um80i6ix3y0ewwc8i94y5lcicm2zl5
28 Dec 21
A process and equipment assembly for reacting a substituent precursor with a cyclodextrin starting material to provide a raw product comprising a cyclodextrin derivative and 1% or less of an initial amount of the substituent precursor is provided.
Vincent D. Antle, Jose R. Matos
Filed: 24 Jan 20
Utility
iuci3m9o61kowgthp9k8rgb40ps8l8r4p3fyp48203nhd0rk
9 Dec 21
The present invention is directed to pharmaceutical compositions comprising melphalan and a cyclodextrin derivative, and methods of making and using the same.
James D. Pipkin, Stephen G. Machatha
Filed: 8 Mar 21
Utility
z72sd0 pex97rf4311qpj54ug47mrkgyizeansz7cwqul
1 Jun 21
The present disclosure is directed to pharmaceutical compositions comprising a nitrogen mustard and a cyclodextrin derivative, and methods of making and using the same.
James D. Pipkin, Stephen G. Machatha
Filed: 28 Mar 14
Utility
oe16zzlh ot6j1kfxj0ggvewp9u1f3e89oiscnhltotu6yp99lpfqvms
20 May 21
The present invention relates to compositions comprising fractionated alkylated cyclodextrin compositions having a single degree of substitution, and processes for preparing and using the same.
Vincent D. Antle, Charles Alan Watson, David W. Miles
Filed: 24 Nov 20
Utility
lxi9 pc4q0jgoicvx2byt7
1 Apr 21
SAE-CD compositions are provided, along with methods of making and using the same.
Vincent D. Antle
Filed: 15 Sep 20
Utility
am3mauxs0481f4f61gmz2d0phijzq913kb41uip1i576q6
9 Mar 21
The present invention is directed to pharmaceutical compositions comprising melphalan and a cyclodextrin derivative, and methods of making and using the same.
James D. Pipkin, Stephen G. Machatha
Filed: 16 Dec 13
Utility
t0qje8yp1pdjrgk8p8lecvjsh yp4zy235g0lytq
18 Feb 21
The present disclosure is directed to pharmaceutical compositions comprising a nitrogen mustard and a cyclodextrin derivative, and methods of making and using the same.
James D. Pipkin, Stephen G. Machatha
Filed: 29 Oct 20
Utility
25ulhf1o0xibk437umgynwlkjqv7l8sh
14 Dec 20
The present disclosure is directed to pharmaceutical compositions comprising a nitrogen mustard and a cyclodextrin derivative, and methods of making and using the same.
James D. Pipkin, Stephen G. Machatha
Filed: 26 Dec 19