17 patents
Utility
Treatment of cholangiopathies
4 Aug 22
Seladelpar and its salts are useful in the treatment of cholangiopathies in subjects who are intolerant of, or have an inadequate response to, obeticholic acid and/or fibrates.
Yun-Jung Choi, Charles A. McWherter, Alexandra S. Steinberg, Ke Yang
Filed: 29 Jan 22
Utility
CB-0406 tromethamine salt
18 Nov 21
CB-0406 tromethamine salt, especially in crystalline form and as an ansolvate, methods of preparing it, compositions containing it, and its pharmaceutical uses.
Stephan X.M. Boerrigter, Charles A. McWherter, Robert L. Martin, Jennifer L. Nelson, Jiangao Song
Filed: 12 May 21
Utility
CB-0406 choline salt
18 Nov 21
CB-0406 choline salt, especially in crystalline form and as an ansolvate, methods of preparing it, compositions containing it, and its pharmaceutical uses.
Stephan X.M. Boerrigter, Charles A. McWherter, Robert L. Martin, Jennifer L. Nelson, Jiangao Song
Filed: 12 May 21
Utility
Treatment of cholestatic pruritus
16 Sep 21
Treatment of cholestatic pruritus by therapy with seladelpar or a salt thereof.
Pol Boudes, Charles A. McWherter, Alexandra S. Steinberg
Filed: 21 Dec 20
Utility
Treatment of intrahepatic cholestatic diseases
22 Jul 21
Treatment of intrahepatic cholestatic diseases by therapy with seladelpar or a salt thereof.
Pol Boudes, Charles A. McWherter
Filed: 3 Apr 21
Utility
Treatment of intestinal barrier dysfunction and associated diseases
20 May 21
Treatment of intestinal barrier dysfunction and associated diseases other than alcoholic liver disease or NAFLD/NASH with seladelpar or a salt thereof.
Edward E. Cable
Filed: 12 Nov 20
Utility
Treatment of alcoholic liver disease
20 May 21
Treatment of alcoholic liver disease with seladelpar or a salt thereof.
Edward E. Cable
Filed: 12 Nov 20
Utility
Treatment of NAFLD and NASH
11 Feb 21
Treatment of NAFLD and NASH by therapy with MBX-8025 or an MBX-8025 salt.
Brian Roberts, Xueyan Wang, Yun-Jung Choi, David Karpf, Robert Martin, Charles McWherter
Filed: 19 Jun 20
Utility
Treatment of intrahepatic cholestatic diseases
28 Jan 21
Treatment of intrahepatic cholestatic diseases by therapy with MBX-8025 or an MBX-8025 salt.
Pol Boudes, Charles A. McWherter
Filed: 3 Oct 20
Utility
Treatment of intrahepatic cholestatic diseases
6 Jan 21
Treatment of intrahepatic cholestatic diseases by therapy with seladelpar or a salt thereof.
Pol Boudes, Charles A. McWherter
Filed: 17 Sep 20
Utility
Treatment of intrahepatic cholestatic diseases
6 Jan 21
Treatment of intrahepatic cholestatic diseases by therapy with seladelpar or a salt thereof.
Pol Boudes, Charles A. McWherter
Filed: 17 Sep 20
Utility
Treatment of obesity and its complications
20 May 20
Combination treatment of obesity and its complications with seladelpar or a salt thereof and a glucagon-like peptide-1 (GLP-1) receptor agonist.
Yun-Jung Choi, Charles A McWherter
Filed: 12 Nov 19
Utility
Combination treatment of NAFLD and NASH
20 May 20
Combination treatment of NAFLD, including NASH, with seladelpar or a salt thereof and a glucagon-like peptide-1 (GLP-1) receptor agonist.
Yun-Jung Choi, Charles A. McWherter
Filed: 12 Nov 19
Utility
Treatment of intrahepatic cholestatic diseases
29 Apr 20
Treatment of intrahepatic cholestatic diseases by therapy with seladelpar or a salt thereof.
Pol Boudes, Charles A. McWherter
Filed: 5 Nov 19
Utility
Treatment of intrahepatic cholestatic diseases
26 Feb 20
Treatment of intrahepatic cholestatic diseases by therapy with seladelpar or a salt thereof.
Pol Boudes, Charles A. McWherter
Filed: 8 Oct 19
Utility
Treatment of NAFLD and NASH
8 Jan 20
Treatment of NAFLD and NASH by therapy with MBX-8025 or an MBX-8025 salt.
Brian Roberts, Xueyan Wang, Yun-Jung Choi, David Karpf, Robert Martin, Charles McWherter
Filed: 22 May 19
Utility
Methods of Reducing Small, Dense LDL Particles
2 Oct 19
The present invention provides methods for increasing LDL particle size.
David Karpf, Ronald M. Krauss, Yun-Jung Choi, Xueyan Wang, Francine M. Gregoire
Filed: 30 Oct 18
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