8 patents
Utility
Antiviral benzyl-amine phosphodiamide compounds
21 Sep 21
Manuel de Lera Ruiz, Timothy J. Hartingh, Izzat Raheem, John Schreier, Jean-Laurent Paparin
Filed: 19 Dec 17
Utility
Carbocyclic nucleoside reverse transcriptase inhibitors
22 Jun 21
Francois-Rene Alexandre, Rachid Rahali, Izzat Raheem, Christophe Parsy
Filed: 6 Dec 18
Utility
2′-branched nucleosides and flaviviridae mutation
6 Jan 20
The present invention discloses a method for the treatment of Flaviviridae infection that includes the administration of a 2′-branched nucleoside, or a pharmaceutically acceptable prodrug and/or salt thereof, to a human in need of therapy in combination or alternation with a drug that directly or indirectly induces a mutation in the viral genome at a location other than a mutation of a nucleotide that results in a change from serine to a different amino acid in the highly conserved consensus sequence, XRXSGXXXT (SEQ ID NO: 63), of domain B of the RNA polymerase region, or is associated with such a mutation.
Jean-Pierre Sommadossi, Paolo La Colla, David N. Standring, Vadim Bichko, Lin Qu
Filed: 15 Dec 15
Utility
Antiviral aliphatic ester prodrugs of tenofovir
30 Dec 19
Jean-Laurent Paparin, Izzat Raheem, Houcine Rahali, Daniel Da Costa, David Dukhan
Filed: 19 Dec 17
Utility
2′-chloro nucleoside analogs for HCV infection
23 Dec 19
Gilles Gosselin, Christophe Claude Parsy, Francois-Rene Alexandre, Houcine Rahali, Jean-Francois Griffon, Dominique Surleraux, Cyril B. Dousson, Claire Pierra, Adel M. Moussa, Benjamin Alexander Mayes, Alistair James Stewart
Filed: 6 Oct 13
Utility
Cyclic Phosphate Substituted Nucleoside Derivatives for the Treatment of Liver Diseases
4 Dec 19
Cyril Dousson, David Dukhan, Christophe C. Parsy, Stephane L. Bogen
Filed: 14 Nov 17
Utility
Antiviral Benzyl-amine Phosphodiamide Compounds
23 Oct 19
Manuel de Lera Ruiz, Timothy J. Hartingh, Izzat Raheem, John Schreier, Jean-Laurent Paparin
Filed: 18 Dec 17
Utility
Antiviral prodrugs of tenofovir
21 Oct 19
Compounds of Formula I: and pharmaceutically acceptable salts and co-crystals thereof are useful for the inhibition of HIV reverse transcriptase.
Daniel Da Costa, Cyril B. Dousson, David Dukhan, Jean-Laurent Paparin, Houcine Rahali, Izzat Raheem
Filed: 21 Aug 17
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