89 patents
Page 5 of 5
Utility
Antibodies and Methods of Use Thereof
22 Jan 20
Provided are antibodies that specifically bind to CTLA-4 and/or PD-1 and antagonize CTLA-4 and/or PD-1 function.
Marc VAN DIJK, Cornelia Anne MUNDT, Gerd RITTER, David SCHAER, Jedd David WOLCHOK, Taha MERGHOUB, Nicholas Stuart WILSON, David Adam SAVITSKY, Mark Arthur FINDEIS, Roberta ZAPPASODI, Rikke Bæk HOLMGAARD, Jean-Marie CUILLEROT, Igor PROSCURSHIM, Olga SHEBANOVA
Filed: 6 Jun 19
Utility
Heat Shock Protein-binding Peptide Compositions and Methods of Use Thereof
1 Jan 20
Provided are polypeptides and compositions comprising novel HSP-binding peptides.
Mark Arthur Findeis, Benjamin Maxime Morin, Bishnu Joshi
Filed: 24 Apr 19
Utility
Identification of antigen- or ligand-specific binding proteins
9 Dec 19
The present invention discloses novel methods for the generation, expression and screening of diverse collections of binding proteins such as antibodies or fragments thereof in vertebrate host cells in vitro, for the identification and isolation of ligand- or antigen-specific binding proteins.
Ulf Grawunder, Jorn Stitz
Filed: 26 Jan 17
Utility
ANTI-OX40 Antibodies, Anti-gitr Antibodies, and Methods of Use Thereof
4 Dec 19
The present disclosure provides antibodies that specifically bind to human OX40 receptor (OX40) and/or human GITR receptor (GITR), including multispecific antibodies that bind, e.g., to OX40 and GITR, and compositions comprising such antibodies.
Nicholas S. WILSON, Jeremy D. WAIGHT, Dennis J. UNDERWOOD, Ekaterina V. BREOUS-NYSTROM, Gerd RITTER, David SCHAER, Daniel HIRSCHHORN-CYMERMAN, Taha MERGHOUB, Marc VAN DIJK
Filed: 8 May 19
Utility
ANTI-CD73 Antibodies and Methods of Use Thereof
20 Nov 19
The instant disclosure provides antibodies that specifically bind to CD73 (e.g., human CD73) and antagonize CD73 function.
Nicholas Stuart Wilson, Jeremy Dale Waight, Shawn Michael Jennings, Olga Ignatovich, Emmanuel Cyrille Pascal Briend, Benjamin Maxime Morin, Oliver Schon, Spencer Campbell
Filed: 7 Mar 19
Utility
ANTI-OX40 Antibodies and Methods of Use Thereof
20 Nov 19
The present disclosure provides antibodies that specifically bind to human OX40 receptor (OX40) and compositions comprising such antibodies.
Marc VAN DIJK, Ekaterina V. BREOUS-NYSTROM, Volker SEIBERT, Gerd RITTER, David SCHAER, Daniel HIRSCHHORN-CYMERMAN, Taha MERGHOUB, Hao TANG, David A. SAVITSKY, Jeremy WAIGHT, Nicholas S. WILSON
Filed: 14 Apr 19
Utility
Anti-CTLA-4 antibodies and methods of use thereof
18 Nov 19
The instant disclosure provides antibodies that specifically bind to human CTLA-4 and antagonize CTLA-4 function.
Marc van Dijk, Cornelia Anne Mundt, Gerd Ritter, David Schaer, Jedd David Wolchok, Taha Merghoub, David Adam Savitsky, Nicholas Stuart Wilson
Filed: 18 Oct 18
Utility
Anti-PD-1 antibodies and methods of use thereof
21 Oct 19
The instant disclosure provides antibodies that specifically bind to human PD-1 and antagonize PD-1 function.
Marc Van Dijk, Cornelia Anne Mundt, Gerd Ritter, Jedd David Wolchok, Taha Merghoub, Roberta Zappasodi, Rikke Baek Holmgaard, David Schaer, David Adam Savitsky, Nicholas Stuart Wilson
Filed: 29 Apr 19
Utility
Anti-gitr Antibodies and Methods of Use Thereof
9 Oct 19
The present disclosure provides antibodies that specifically bind to human glucocorticoid-induced TNFR family related receptor (GITR) and compositions comprising such antibodies.
Volker SEIBERT, Olivier LÉGER, Marc VAN DIJK, Taha MERGHOUB, David SCHAER, Gerd RITTER, Takemasa TSUJI
Filed: 14 Mar 19