8 patents
Utility
Compositions and Methods for Modulating Immune Responses
6 Jan 22
The present invention provides a newly identified B7 receptor, zB7R1 that functions as lymphocyte inhibitory receptor, which is a PD-1-like molecule and is expressed on T cells.
Zeren GAO, Steven D. LEVIN, Janine M. BILSBOROUGH, James W. West, Cameron S. BRANDT, Eric M. Chadwick
Filed: 23 Sep 21
Utility
Levels of Bcma Protein Expression on B Cells and Use In Diagnostic Methods of Treating Systemic Lupus Erythematosus
13 May 21
The present invention provides a method of measuring the levels of BCMA in a biological sample, specifically upon the B cell surface.
Stacey R. Dillon, Jane A. Gross
Filed: 8 Dec 20
Utility
Methods of Treating Pruritic Disease with IL-31 Monoclonal Antibodies
19 Aug 20
The invention provides humanized mouse anti-human IL-31 antibodies and antibody fragments that are capable of binding IL-31 and thereby neutralizing, inhibiting, limiting, or reducing the proinflammatory or pro-pruritic effects of IL-31.
Kent Bondensgaard, Roland Beckmann
Filed: 29 Mar 20
Utility
Methods of Treating Prurigo Nodularis Using ANTI-IL-31RA Antibody Compositions
29 Jul 20
The present invention relates to methods of treating patients suffering from Contact dermatitis, Drug induced delayed type cutaneous allergic reactions, Toxic epidermal necrolysis, Cutaneous T cell Lymphoma, Bullous pemphigoid, Alopecia aereata, Vitiligo, Acne Rosacea, Prurigo nodularis, Scleroderma, Herpes simplex virus, or combination by administering an IL-31RA antagonist.
Janine M. Bilsborough
Filed: 27 Feb 20
Utility
Treating Inflammation with Soluble Hybrid Fcgamma Receptors
29 Apr 20
Disclosed are soluble hybrid Fcγ receptor (FcγR) polypeptide compositions and related methods of using such polypeptides to treat IgG-mediated and immune complex-mediated inflammation.
Carl W. BIRKS, Brian A.. FOX, Mark W. RIXON, Jeff L. ELLSWORTH
Filed: 7 Jan 20
Utility
Use of IL-31 Monoclonal Antibodies for Treating Prurigo Nodularis
11 Dec 19
Novel compositions derived from antigen-binding sites of immunoglobulins having affinity for IL-31 are provided.
Anthony W. Siadak, Janine M. Bilsborough, Shirley A. Rene
Filed: 21 Aug 19
Utility
Compositions and Methods for Modulating Immune Responses
11 Dec 19
The present invention provides a newly identified B7 receptor, zB7R1 that functions as lymphocyte inhibitory receptor, which is a PD-1-like molecule and is expressed on T cells.
Zeren GAO, Steven D. LEVIN, Janine M. BILSBOROUGH, James W. WEST, Cameron S. BRANDT, Eric M. Chadwick
Filed: 13 Aug 19
Utility
IL-31 Antibody Compositions
6 Nov 19
The present invention relates to zcytor17lig polynucleotide, polypeptide and anti-zcytor17 antibody molecules.
Cindy A. Sprecher, Joseph L. Kuijper, Maria M. Dasovich, Francis J. Grant, Jane A. Gross, Angela K. Hammond
Filed: 26 Sep 18
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