7 patents
Utility
Composition of Novel Carbohydrate Drug for Treatment of Human Diseases
5 Jan 23
Aspects of the invention provide compositions for use in the treatment galectin-dependent diseases.
Eliezer ZOMER, Peter G. TRABER, Anatole A. KLYOSOV, Elena CHEKHOVA
Filed: 29 Jun 22
Utility
Methods for treatment of arthritis
16 Aug 22
Aspects of the invention provide compositions for use in the treatment galectin-dependent diseases.
Eliezer Zomer, Peter G. Traber, Anatole A. Klyosov, Elena Chekhova
Filed: 28 Sep 20
Utility
Composition of Novel Carbohydrate Drug for Treatment of Human Diseases
1 Apr 21
Aspects of the invention provide compositions for use in the treatment galectin-dependent diseases.
Eliezer Zomer, Peter G. Traber, Anatole A. Klyosov, Elena Chekhova
Filed: 28 Sep 20
Utility
Compositions Comprising Galactose-Pronged Polysaccharides
14 Jan 21
Methods and compositions for reducing fibrosis and cirrhosis are provided in which an effective dose of an admixture of a polysaccharide compound and, for example, a compound selected from the group consisting of antibodies specific to intracellular or cell-surface: (i) beta-PDGF receptors; (ii) synaptophysin; (iii) zvegf3; (iv) CCR1 receptors; (v) connective tissue growth factor; (vi) alpha 1-smooth muscle actin; (vii) matrix metalloproteinases MMP 2 and MMP9; (viii) matrix metalloproteinase inhibitors TIMP1 and TMP2; (ix) integrins; (x) TFG-β1; (xi) endothelin receptor antagonists; and (xii) collagen synthesis and degradation modulating compounds; (xiii) actin synthesis and degradation modulating compounds; and (xiv) tyrosine kinases is administered to an animal in order to treat fibrosis.
David Platt, Eliezer Zomer, Anatole Klyosov
Filed: 3 Aug 20
Utility
Composition of novel carbohydrate drug for treatment of human diseases
12 Oct 20
Aspects of the invention provide compositions for use in the treatment galectin-dependent diseases.
Eliezer Zomer, Peter G. Traber, Anatole A. Klyosov, Elena Chekhova
Filed: 29 Jul 19
Utility
Galactose-pronged polysaccharides in a formulation for antifibrotic therapies
17 Aug 20
Methods and compositions for reducing fibrosis and cirrhosis are provided in which an effective dose of an admixture of a polysaccharide compound and, for example, a compound selected from the group consisting of antibodies specific to intracellular or cell-surface: (i) beta-PDGF receptors; (ii) synaptophysin; (iii) zvegf3; (iv) CCR1 receptors; (v) connective tissue growth factor; (vi) alpha 1-smooth muscle actin; (vii) matrix metalloproteinases MMP 2 and MMP9; (viii) matrix metalloproteinase inhibitors TIMP1 and TMP2; (ix) integrins; (x) TFG-β1; (xi) endothelin receptor antagonists; and (xii) collagen synthesis and degradation modulating compounds; (xiii) actin synthesis and degradation modulating compounds; and (xiv) tyrosine kinases is administered to an animal in order to treat fibrosis.
David Platt, Eliezer Zomer, Anatole Klyosov
Filed: 27 Aug 17
Utility
Composition of Novel Carbohydrate Drug for Treatment of Human Diseases
11 Mar 20
Aspects of the invention provide compositions for use in the treatment galectin-dependent diseases.
Eliezer Zomer, Peter G. Traber, Anatole A. Klyosov, Elena Chekhova
Filed: 29 Jul 19
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