31 patents
Page 2 of 2
Utility
Ciprofloxacin Polymorph and Its Use
5 Aug 20
The present disclosure relates to ciprofloxacin polymorphs and their use in treating infections.
Mark WILLIAMS, Jacob SITTENAUER, Shelby CLARK, Joseph FARTHING, Michael BALTEZOR, Matthew MCCLOREY
Filed: 27 Sep 18
Utility
Methods for Solid Tumor Treatment
17 Jun 20
Disclosed herein are methods for treating solid tumors by direct injection into the tumors of chemotherapeutic particles, methods for inhibiting tumor metastasis by administering chemotherapeutic particles to a subject having a tumor, and compositions that include chemotherapeutic particles, small amounts of a polysorbate, and a carrier.
Mike Baltezor, Gere diZerega, Charles Decedue, Sam Campbell, Matt McClorey
Filed: 12 Dec 19
Utility
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17 Jun 20
Disclosed herein are methods for treating solid tumors by direct injection into the tumors of chemotherapeutic particles, methods for inhibiting tumor metastasis by administering chemotherapeutic particles to a subject having a tumor, and compositions that include chemotherapeutic particles, small amounts of a polysorbate, and a carrier.
Mike Baltezor, Gere diZerega, Charles Decedue, Sam Campbell, Matt McClorey
Filed: 12 Dec 19
Utility
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27 May 20
Compositions are provided that include having at least 95% by weight of a taxane, or a pharmaceutically acceptable salt thereof, where the particles have a mean bulk density between about 0.050 g/cm3 and about 0.15 g/cm3, and/or a specific surface area (SSA) of at least 18 m2/g, 20 m2/g, 25 m2/g, 30 m2/g, 32 m2/g, 34 m2/g, or 35 m2/g.
Michael BALTEZOR, Joseph FARTHING, Jake SITTENAUER, Jahna ESPINOSA, Samuel CAMPBELL, Matthew MCCLOREY, Julia K. FISCHER, Mark D. WILLIAMS, Gary E. CLAPP
Filed: 29 Jan 20
Utility
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1 Apr 20
Compositions are provided that include having at least 95% by weight of a taxane, or a pharmaceutically acceptable salt thereof, where the particles have a mean bulk density between about 0.050 g/cm3 and about 0.15 g/cm3, and/or a specific surface area (SSA) of at least 18 m2/g, 20 m2/g, 25 m2/g, 30 m2/g, 32 m2/g, 34 m2/g, or 35 m2/g.
Michael BALTEZOR, Joseph FARTHING, Jake SITTENAUER, Jahna ESPINOSA, Samuel CAMPBELL, Matthew MCCLOREY, Julia K. FISCHER, Mark D. WILLIAMS, Gary E. CLAPP
Filed: 29 Oct 19
Utility
37u8q30rj9io5worgtotwhzp5la0 8abbcy1eulinoh06lg9vcc
26 Feb 20
Disclosed herein are compositions and methods for treating lung disorders including lung tumors by pulmonary administration of compositions comprising taxane particles such as docetaxel or paclitaxel particles.
Michael Baltezor, Matthew McClorey, William Johnston, Gere S. diZerega, James Verco
Filed: 30 Oct 19
Utility
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4 Dec 19
Disclosed are methods useful for the therapeutic treatment of cancerous solid tumors by the administration of an antineoplastic agent, wherein the antineoplastic agent resides at the tumor site exposing the tumor to the antineoplastic agent for a sustained amount of time sufficient to stimulate the endogenous immune system of the subject resulting in the production of tumoricidal cells and infiltration of the tumoricidal cells in and around the tumor site at a level sufficient to treat the tumor.
Michael BALTEZOR, Sam CAMPBELL, Charles J. DECEDUE, Gere S. DIZEREGA, William JOHNSTON, Matthew MCCLOREY, James VERCO
Filed: 3 Jan 19
Utility
rqft7fguw5fycpi8vna82igmhrg hxacgjo8a11dqe4gg77a5oslug
4 Dec 19
Disclosed herein are compositions and methods for treating kidney tumors by intratumoral injection administration of compositions comprising taxane particles such as docetaxel particles or paclitaxel particles.
Michael BALTEZOR, Gere DIZEREGA, Charles J. DECEDUE, Sam CAMPBELL, Matthew MCCLOREY, Holly MAULHARDT
Filed: 3 Jan 19
Utility
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4 Dec 19
Disclosed are methods for the isolation of tumor-specific immune cells from subjects that have a malignant tumor and have received local administration of a composition comprising taxane particles to the malignant tumor, and use of such isolated immune cells in compositions for adoptive cell therapy and cancer vaccines.
Gere S. Dizerega, Holly Maulhardt, Michael Baltezor, Sam Campbell, Charles J. Decedue, William Johnston, Matthew McClorey, James Verco
Filed: 11 Apr 19
Utility
h4uvvejjn8nb6czw34a19l6memplg
13 Nov 19
Disclosed herein are methods for treating solid tumors by direct injection into the tumors of chemotherapeutic particles, methods for inhibiting tumor metastasis by administering chemotherapeutic particles to a subject having a tumor, and compositions that include chemotherapeutic particles, small amounts of a polysorbate, and a carrier.
Mike Baltezor, Gere diZerega, Charles Decedue, Sam Campbell, Matt McClorey
Filed: 14 Jul 19
Utility
k3c1a9av70zmzv280p99c3zxw34cyoka00cjbef388hi
16 Oct 19
Disclosed herein are compositions and methods for treating lung disorders including lung tumors by pulmonary administration of compositions comprising taxane particles such as docetaxel or paclitaxel particles.
Michael Baltezor, Matthew McClorey, William Johnston, Gere S. diZerega, James Verco
Filed: 17 Jun 19